LeishMANIAdb
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Guanylate cyclase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Guanylate cyclase
Gene product:
mitogen-activated protein kinase-like protein
Species:
Leishmania major
UniProt:
Q4Q1Y5_LEIMA
TriTrypDb:
LmjF.36.0910 , LMJLV39_360014800 * , LMJSD75_360014800 *
Length:
1562

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
Term Name Level Count
GO:0016020 membrane 2 6
GO:0110165 cellular anatomical entity 1 6

Expansion

Sequence features

Q4Q1Y5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 7
GO:0006163 purine nucleotide metabolic process 5 7
GO:0006164 purine nucleotide biosynthetic process 6 7
GO:0006171 cAMP biosynthetic process 8 7
GO:0006182 cGMP biosynthetic process 8 7
GO:0006468 protein phosphorylation 5 7
GO:0006725 cellular aromatic compound metabolic process 3 7
GO:0006753 nucleoside phosphate metabolic process 4 7
GO:0006793 phosphorus metabolic process 3 7
GO:0006796 phosphate-containing compound metabolic process 4 7
GO:0006807 nitrogen compound metabolic process 2 7
GO:0007165 signal transduction 2 2
GO:0008152 metabolic process 1 7
GO:0009058 biosynthetic process 2 7
GO:0009117 nucleotide metabolic process 5 7
GO:0009150 purine ribonucleotide metabolic process 6 7
GO:0009152 purine ribonucleotide biosynthetic process 7 7
GO:0009165 nucleotide biosynthetic process 6 7
GO:0009187 cyclic nucleotide metabolic process 6 7
GO:0009190 cyclic nucleotide biosynthetic process 7 7
GO:0009259 ribonucleotide metabolic process 5 7
GO:0009260 ribonucleotide biosynthetic process 6 7
GO:0009987 cellular process 1 7
GO:0016310 phosphorylation 5 7
GO:0018130 heterocycle biosynthetic process 4 7
GO:0019438 aromatic compound biosynthetic process 4 7
GO:0019538 protein metabolic process 3 7
GO:0019637 organophosphate metabolic process 3 7
GO:0019693 ribose phosphate metabolic process 4 7
GO:0034641 cellular nitrogen compound metabolic process 3 7
GO:0034654 nucleobase-containing compound biosynthetic process 4 7
GO:0036211 protein modification process 4 7
GO:0043170 macromolecule metabolic process 3 7
GO:0043412 macromolecule modification 4 7
GO:0044237 cellular metabolic process 2 7
GO:0044238 primary metabolic process 2 7
GO:0044249 cellular biosynthetic process 3 7
GO:0044271 cellular nitrogen compound biosynthetic process 4 7
GO:0044281 small molecule metabolic process 2 7
GO:0046058 cAMP metabolic process 7 7
GO:0046068 cGMP metabolic process 7 7
GO:0046390 ribose phosphate biosynthetic process 5 7
GO:0046483 heterocycle metabolic process 3 7
GO:0050789 regulation of biological process 2 2
GO:0050794 regulation of cellular process 3 2
GO:0052652 cyclic purine nucleotide metabolic process 6 7
GO:0055086 nucleobase-containing small molecule metabolic process 3 7
GO:0065007 biological regulation 1 2
GO:0071704 organic substance metabolic process 2 7
GO:0072521 purine-containing compound metabolic process 4 7
GO:0072522 purine-containing compound biosynthetic process 5 7
GO:0090407 organophosphate biosynthetic process 4 7
GO:1901135 carbohydrate derivative metabolic process 3 7
GO:1901137 carbohydrate derivative biosynthetic process 4 7
GO:1901293 nucleoside phosphate biosynthetic process 5 7
GO:1901360 organic cyclic compound metabolic process 3 7
GO:1901362 organic cyclic compound biosynthetic process 4 7
GO:1901564 organonitrogen compound metabolic process 3 7
GO:1901566 organonitrogen compound biosynthetic process 4 7
GO:1901576 organic substance biosynthetic process 3 7
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 7
GO:0003824 catalytic activity 1 7
GO:0004672 protein kinase activity 3 7
GO:0005488 binding 1 7
GO:0005524 ATP binding 5 7
GO:0016301 kinase activity 4 7
GO:0016740 transferase activity 2 7
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 7
GO:0016773 phosphotransferase activity, alcohol group as acceptor 4 7
GO:0017076 purine nucleotide binding 4 7
GO:0030554 adenyl nucleotide binding 5 7
GO:0032553 ribonucleotide binding 3 7
GO:0032555 purine ribonucleotide binding 4 7
GO:0032559 adenyl ribonucleotide binding 5 7
GO:0035639 purine ribonucleoside triphosphate binding 4 7
GO:0036094 small molecule binding 2 7
GO:0043167 ion binding 2 7
GO:0043168 anion binding 3 7
GO:0097159 organic cyclic compound binding 2 7
GO:0097367 carbohydrate derivative binding 2 7
GO:0140096 catalytic activity, acting on a protein 2 7
GO:1901265 nucleoside phosphate binding 3 7
GO:1901363 heterocyclic compound binding 2 7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1143 1147 PF00656 0.684
CLV_C14_Caspase3-7 1447 1451 PF00656 0.524
CLV_C14_Caspase3-7 774 778 PF00656 0.538
CLV_MEL_PAP_1 560 566 PF00089 0.448
CLV_NRD_NRD_1 103 105 PF00675 0.352
CLV_NRD_NRD_1 1089 1091 PF00675 0.380
CLV_NRD_NRD_1 1397 1399 PF00675 0.279
CLV_NRD_NRD_1 1550 1552 PF00675 0.309
CLV_NRD_NRD_1 172 174 PF00675 0.445
CLV_NRD_NRD_1 432 434 PF00675 0.525
CLV_NRD_NRD_1 547 549 PF00675 0.456
CLV_NRD_NRD_1 63 65 PF00675 0.387
CLV_NRD_NRD_1 67 69 PF00675 0.408
CLV_NRD_NRD_1 962 964 PF00675 0.411
CLV_NRD_NRD_1 980 982 PF00675 0.274
CLV_NRD_NRD_1 998 1000 PF00675 0.240
CLV_PCSK_FUR_1 998 1002 PF00082 0.263
CLV_PCSK_KEX2_1 1027 1029 PF00082 0.440
CLV_PCSK_KEX2_1 103 105 PF00082 0.319
CLV_PCSK_KEX2_1 1089 1091 PF00082 0.391
CLV_PCSK_KEX2_1 1550 1552 PF00082 0.309
CLV_PCSK_KEX2_1 171 173 PF00082 0.465
CLV_PCSK_KEX2_1 432 434 PF00082 0.616
CLV_PCSK_KEX2_1 534 536 PF00082 0.569
CLV_PCSK_KEX2_1 547 549 PF00082 0.473
CLV_PCSK_KEX2_1 638 640 PF00082 0.385
CLV_PCSK_KEX2_1 67 69 PF00082 0.401
CLV_PCSK_KEX2_1 962 964 PF00082 0.411
CLV_PCSK_KEX2_1 980 982 PF00082 0.469
CLV_PCSK_KEX2_1 998 1000 PF00082 0.278
CLV_PCSK_PC1ET2_1 1000 1002 PF00082 0.311
CLV_PCSK_PC1ET2_1 1027 1029 PF00082 0.439
CLV_PCSK_PC1ET2_1 534 536 PF00082 0.569
CLV_PCSK_PC1ET2_1 638 640 PF00082 0.385
CLV_PCSK_SKI1_1 1151 1155 PF00082 0.490
CLV_PCSK_SKI1_1 1210 1214 PF00082 0.389
CLV_PCSK_SKI1_1 256 260 PF00082 0.503
CLV_PCSK_SKI1_1 278 282 PF00082 0.514
CLV_PCSK_SKI1_1 531 535 PF00082 0.579
CLV_PCSK_SKI1_1 641 645 PF00082 0.356
CLV_PCSK_SKI1_1 654 658 PF00082 0.300
CLV_PCSK_SKI1_1 677 681 PF00082 0.297
CLV_PCSK_SKI1_1 943 947 PF00082 0.323
DEG_APCC_DBOX_1 1088 1096 PF00400 0.681
DEG_APCC_DBOX_1 202 210 PF00400 0.521
DEG_APCC_DBOX_1 277 285 PF00400 0.311
DEG_MDM2_SWIB_1 307 315 PF02201 0.276
DEG_SCF_FBW7_1 1194 1201 PF00400 0.535
DEG_SCF_FBW7_1 1454 1461 PF00400 0.524
DEG_SCF_TRCP1_1 838 844 PF00400 0.437
DOC_CKS1_1 136 141 PF01111 0.566
DOC_CYCLIN_yClb1_LxF_4 278 284 PF00134 0.261
DOC_CYCLIN_yCln2_LP_2 1174 1177 PF00134 0.631
DOC_CYCLIN_yCln2_LP_2 32 38 PF00134 0.583
DOC_MAPK_gen_1 1398 1406 PF00069 0.483
DOC_MAPK_gen_1 208 217 PF00069 0.535
DOC_MAPK_gen_1 463 472 PF00069 0.347
DOC_MAPK_gen_1 537 545 PF00069 0.306
DOC_MAPK_gen_1 758 766 PF00069 0.500
DOC_MAPK_HePTP_8 209 221 PF00069 0.524
DOC_MAPK_MEF2A_6 210 219 PF00069 0.538
DOC_MAPK_MEF2A_6 587 595 PF00069 0.314
DOC_MAPK_MEF2A_6 760 768 PF00069 0.509
DOC_PP1_RVXF_1 998 1005 PF00149 0.533
DOC_PP2B_LxvP_1 1174 1177 PF13499 0.609
DOC_PP2B_LxvP_1 303 306 PF13499 0.330
DOC_PP2B_LxvP_1 32 35 PF13499 0.576
DOC_PP2B_LxvP_1 50 53 PF13499 0.526
DOC_PP4_FxxP_1 1460 1463 PF00568 0.487
DOC_PP4_FxxP_1 382 385 PF00568 0.263
DOC_PP4_FxxP_1 816 819 PF00568 0.502
DOC_USP7_MATH_1 102 106 PF00917 0.557
DOC_USP7_MATH_1 1034 1038 PF00917 0.579
DOC_USP7_MATH_1 1094 1098 PF00917 0.590
DOC_USP7_MATH_1 1123 1127 PF00917 0.682
DOC_USP7_MATH_1 1140 1144 PF00917 0.590
DOC_USP7_MATH_1 1235 1239 PF00917 0.595
DOC_USP7_MATH_1 1255 1259 PF00917 0.620
DOC_USP7_MATH_1 128 132 PF00917 0.648
DOC_USP7_MATH_1 140 144 PF00917 0.625
DOC_USP7_MATH_1 775 779 PF00917 0.547
DOC_USP7_UBL2_3 943 947 PF12436 0.498
DOC_WW_Pin1_4 1051 1056 PF00397 0.503
DOC_WW_Pin1_4 1119 1124 PF00397 0.756
DOC_WW_Pin1_4 1180 1185 PF00397 0.707
DOC_WW_Pin1_4 1194 1199 PF00397 0.516
DOC_WW_Pin1_4 135 140 PF00397 0.692
DOC_WW_Pin1_4 141 146 PF00397 0.696
DOC_WW_Pin1_4 1454 1459 PF00397 0.527
DOC_WW_Pin1_4 156 161 PF00397 0.579
DOC_WW_Pin1_4 314 319 PF00397 0.295
DOC_WW_Pin1_4 351 356 PF00397 0.231
DOC_WW_Pin1_4 491 496 PF00397 0.373
DOC_WW_Pin1_4 74 79 PF00397 0.613
DOC_WW_Pin1_4 933 938 PF00397 0.546
LIG_14-3-3_CanoR_1 103 111 PF00244 0.628
LIG_14-3-3_CanoR_1 1031 1037 PF00244 0.587
LIG_14-3-3_CanoR_1 1160 1169 PF00244 0.624
LIG_14-3-3_CanoR_1 1292 1297 PF00244 0.526
LIG_14-3-3_CanoR_1 1459 1463 PF00244 0.459
LIG_14-3-3_CanoR_1 1512 1516 PF00244 0.524
LIG_14-3-3_CanoR_1 203 207 PF00244 0.550
LIG_14-3-3_CanoR_1 278 284 PF00244 0.316
LIG_14-3-3_CanoR_1 369 375 PF00244 0.295
LIG_14-3-3_CanoR_1 537 545 PF00244 0.297
LIG_14-3-3_CanoR_1 639 644 PF00244 0.643
LIG_14-3-3_CanoR_1 654 662 PF00244 0.459
LIG_14-3-3_CanoR_1 67 74 PF00244 0.657
LIG_14-3-3_CanoR_1 699 707 PF00244 0.521
LIG_14-3-3_CanoR_1 735 739 PF00244 0.512
LIG_14-3-3_CanoR_1 758 766 PF00244 0.507
LIG_Actin_WH2_2 520 536 PF00022 0.291
LIG_APCC_ABBA_1 360 365 PF00400 0.331
LIG_APCC_ABBA_1 909 914 PF00400 0.483
LIG_BRCT_BRCA1_1 1096 1100 PF00533 0.571
LIG_BRCT_BRCA1_1 446 450 PF00533 0.295
LIG_BRCT_BRCA1_1 468 472 PF00533 0.310
LIG_BRCT_BRCA1_1 688 692 PF00533 0.549
LIG_CtBP_PxDLS_1 124 128 PF00389 0.554
LIG_deltaCOP1_diTrp_1 309 316 PF00928 0.295
LIG_deltaCOP1_diTrp_1 451 457 PF00928 0.351
LIG_deltaCOP1_diTrp_1 747 756 PF00928 0.534
LIG_EH1_1 89 97 PF00400 0.532
LIG_EH1_1 921 929 PF00400 0.494
LIG_eIF4E_1 1400 1406 PF01652 0.475
LIG_FHA_1 1036 1042 PF00498 0.612
LIG_FHA_1 1195 1201 PF00498 0.724
LIG_FHA_1 1302 1308 PF00498 0.612
LIG_FHA_1 1321 1327 PF00498 0.390
LIG_FHA_1 1346 1352 PF00498 0.424
LIG_FHA_1 1431 1437 PF00498 0.473
LIG_FHA_1 300 306 PF00498 0.302
LIG_FHA_1 321 327 PF00498 0.323
LIG_FHA_1 426 432 PF00498 0.341
LIG_FHA_1 496 502 PF00498 0.315
LIG_FHA_1 544 550 PF00498 0.353
LIG_FHA_1 569 575 PF00498 0.359
LIG_FHA_1 760 766 PF00498 0.487
LIG_FHA_1 890 896 PF00498 0.522
LIG_FHA_2 1052 1058 PF00498 0.508
LIG_FHA_2 1495 1501 PF00498 0.491
LIG_FHA_2 1551 1557 PF00498 0.473
LIG_FHA_2 181 187 PF00498 0.551
LIG_FHA_2 403 409 PF00498 0.388
LIG_FHA_2 520 526 PF00498 0.274
LIG_FHA_2 58 64 PF00498 0.538
LIG_FHA_2 655 661 PF00498 0.504
LIG_FHA_2 855 861 PF00498 0.530
LIG_Integrin_isoDGR_2 504 506 PF01839 0.508
LIG_Integrin_RGD_1 1225 1227 PF01839 0.348
LIG_LIR_Apic_2 1286 1290 PF02991 0.515
LIG_LIR_Apic_2 1457 1463 PF02991 0.488
LIG_LIR_Apic_2 381 385 PF02991 0.272
LIG_LIR_Apic_2 814 819 PF02991 0.504
LIG_LIR_Apic_2 97 102 PF02991 0.562
LIG_LIR_Gen_1 1315 1322 PF02991 0.589
LIG_LIR_Gen_1 325 335 PF02991 0.370
LIG_LIR_Gen_1 451 461 PF02991 0.399
LIG_LIR_Gen_1 558 564 PF02991 0.306
LIG_LIR_Gen_1 588 598 PF02991 0.291
LIG_LIR_Gen_1 665 673 PF02991 0.489
LIG_LIR_Gen_1 804 812 PF02991 0.485
LIG_LIR_LC3C_4 761 766 PF02991 0.554
LIG_LIR_LC3C_4 870 874 PF02991 0.445
LIG_LIR_Nem_3 1057 1061 PF02991 0.616
LIG_LIR_Nem_3 1103 1109 PF02991 0.555
LIG_LIR_Nem_3 1312 1316 PF02991 0.477
LIG_LIR_Nem_3 1367 1373 PF02991 0.473
LIG_LIR_Nem_3 1492 1496 PF02991 0.480
LIG_LIR_Nem_3 302 307 PF02991 0.324
LIG_LIR_Nem_3 406 412 PF02991 0.287
LIG_LIR_Nem_3 451 457 PF02991 0.391
LIG_LIR_Nem_3 558 562 PF02991 0.313
LIG_LIR_Nem_3 588 593 PF02991 0.359
LIG_LIR_Nem_3 665 669 PF02991 0.489
LIG_LIR_Nem_3 747 752 PF02991 0.542
LIG_LIR_Nem_3 804 808 PF02991 0.480
LIG_LIR_Nem_3 849 854 PF02991 0.497
LIG_LIR_Nem_3 944 949 PF02991 0.512
LIG_LYPXL_yS_3 1193 1196 PF13949 0.535
LIG_MLH1_MIPbox_1 1096 1100 PF16413 0.505
LIG_MLH1_MIPbox_1 446 450 PF16413 0.295
LIG_NRBOX 1556 1562 PF00104 0.621
LIG_NRBOX 216 222 PF00104 0.381
LIG_PCNA_yPIPBox_3 432 441 PF02747 0.343
LIG_Pex14_1 453 457 PF04695 0.306
LIG_Pex14_2 307 311 PF04695 0.275
LIG_Pex14_2 449 453 PF04695 0.268
LIG_Pex14_2 812 816 PF04695 0.505
LIG_PTB_Apo_2 236 243 PF02174 0.309
LIG_PTB_Apo_2 298 305 PF02174 0.269
LIG_PTB_Apo_2 660 667 PF02174 0.567
LIG_PTB_Phospho_1 236 242 PF10480 0.308
LIG_PTB_Phospho_1 298 304 PF10480 0.270
LIG_REV1ctd_RIR_1 447 456 PF16727 0.307
LIG_SH2_CRK 1287 1291 PF00017 0.530
LIG_SH2_CRK 242 246 PF00017 0.300
LIG_SH2_CRK 577 581 PF00017 0.289
LIG_SH2_CRK 851 855 PF00017 0.501
LIG_SH2_CRK 932 936 PF00017 0.516
LIG_SH2_NCK_1 1496 1500 PF00017 0.524
LIG_SH2_PTP2 1317 1320 PF00017 0.474
LIG_SH2_SRC 250 253 PF00017 0.300
LIG_SH2_STAP1 1360 1364 PF00017 0.482
LIG_SH2_STAP1 1400 1404 PF00017 0.473
LIG_SH2_STAT3 1410 1413 PF00017 0.499
LIG_SH2_STAT5 1099 1102 PF00017 0.491
LIG_SH2_STAT5 1317 1320 PF00017 0.473
LIG_SH2_STAT5 1376 1379 PF00017 0.608
LIG_SH2_STAT5 1410 1413 PF00017 0.503
LIG_SH2_STAT5 1496 1499 PF00017 0.505
LIG_SH2_STAT5 242 245 PF00017 0.335
LIG_SH2_STAT5 250 253 PF00017 0.299
LIG_SH2_STAT5 304 307 PF00017 0.328
LIG_SH2_STAT5 327 330 PF00017 0.411
LIG_SH2_STAT5 400 403 PF00017 0.272
LIG_SH2_STAT5 411 414 PF00017 0.327
LIG_SH2_STAT5 552 555 PF00017 0.353
LIG_SH2_STAT5 853 856 PF00017 0.528
LIG_SH2_STAT5 884 887 PF00017 0.469
LIG_SH3_2 975 980 PF14604 0.614
LIG_SH3_3 1181 1187 PF00018 0.652
LIG_SH3_3 133 139 PF00018 0.584
LIG_SH3_3 1522 1528 PF00018 0.473
LIG_SH3_3 154 160 PF00018 0.572
LIG_SH3_3 24 30 PF00018 0.572
LIG_SH3_3 286 292 PF00018 0.250
LIG_SH3_3 315 321 PF00018 0.231
LIG_SH3_3 336 342 PF00018 0.296
LIG_SH3_3 346 352 PF00018 0.244
LIG_SH3_3 4 10 PF00018 0.724
LIG_SH3_3 46 52 PF00018 0.591
LIG_SH3_3 675 681 PF00018 0.495
LIG_SH3_3 722 728 PF00018 0.663
LIG_SH3_3 739 745 PF00018 0.502
LIG_SH3_3 931 937 PF00018 0.515
LIG_SH3_3 972 978 PF00018 0.615
LIG_SUMO_SIM_anti_2 1347 1353 PF11976 0.424
LIG_SUMO_SIM_anti_2 1555 1562 PF11976 0.617
LIG_SUMO_SIM_anti_2 261 267 PF11976 0.314
LIG_SUMO_SIM_anti_2 439 445 PF11976 0.332
LIG_SUMO_SIM_anti_2 761 767 PF11976 0.555
LIG_SUMO_SIM_par_1 1042 1049 PF11976 0.532
LIG_SUMO_SIM_par_1 1151 1157 PF11976 0.675
LIG_SUMO_SIM_par_1 154 159 PF11976 0.639
LIG_SUMO_SIM_par_1 1555 1562 PF11976 0.617
LIG_SUMO_SIM_par_1 439 445 PF11976 0.298
LIG_SUMO_SIM_par_1 620 626 PF11976 0.482
LIG_SUMO_SIM_par_1 761 767 PF11976 0.503
LIG_SUMO_SIM_par_1 798 804 PF11976 0.534
LIG_TRAF2_1 1553 1556 PF00917 0.473
LIG_WRC_WIRS_1 1476 1481 PF05994 0.335
LIG_WRC_WIRS_1 280 285 PF05994 0.366
LIG_WRC_WIRS_1 520 525 PF05994 0.403
LIG_WRC_WIRS_1 559 564 PF05994 0.313
LIG_WRC_WIRS_1 809 814 PF05994 0.341
LIG_WRPW_2 676 679 PF00400 0.319
MOD_CDC14_SPxK_1 1183 1186 PF00782 0.449
MOD_CDK_SPK_2 1454 1459 PF00069 0.381
MOD_CDK_SPxK_1 1180 1186 PF00069 0.452
MOD_CDK_SPxxK_3 156 163 PF00069 0.431
MOD_CK1_1 1015 1021 PF00069 0.457
MOD_CK1_1 1023 1029 PF00069 0.508
MOD_CK1_1 1037 1043 PF00069 0.467
MOD_CK1_1 1083 1089 PF00069 0.498
MOD_CK1_1 1098 1104 PF00069 0.315
MOD_CK1_1 1122 1128 PF00069 0.651
MOD_CK1_1 1178 1184 PF00069 0.485
MOD_CK1_1 1202 1208 PF00069 0.496
MOD_CK1_1 1253 1259 PF00069 0.520
MOD_CK1_1 141 147 PF00069 0.551
MOD_CK1_1 1430 1436 PF00069 0.309
MOD_CK1_1 1514 1520 PF00069 0.381
MOD_CK1_1 175 181 PF00069 0.527
MOD_CK1_1 3 9 PF00069 0.660
MOD_CK1_1 319 325 PF00069 0.370
MOD_CK1_1 370 376 PF00069 0.354
MOD_CK1_1 626 632 PF00069 0.528
MOD_CK1_1 683 689 PF00069 0.335
MOD_CK1_1 69 75 PF00069 0.522
MOD_CK1_1 811 817 PF00069 0.352
MOD_CK1_1 839 845 PF00069 0.277
MOD_CK1_1 877 883 PF00069 0.393
MOD_CK2_1 1051 1057 PF00069 0.434
MOD_CK2_1 1309 1315 PF00069 0.381
MOD_CK2_1 1458 1464 PF00069 0.309
MOD_CK2_1 1550 1556 PF00069 0.309
MOD_CK2_1 188 194 PF00069 0.485
MOD_CK2_1 445 451 PF00069 0.308
MOD_CK2_1 519 525 PF00069 0.312
MOD_CK2_1 57 63 PF00069 0.477
MOD_CK2_1 854 860 PF00069 0.386
MOD_CMANNOS 311 314 PF00535 0.387
MOD_GlcNHglycan 1061 1064 PF01048 0.465
MOD_GlcNHglycan 1141 1145 PF01048 0.574
MOD_GlcNHglycan 1210 1213 PF01048 0.631
MOD_GlcNHglycan 1231 1234 PF01048 0.425
MOD_GlcNHglycan 1237 1240 PF01048 0.463
MOD_GlcNHglycan 1250 1253 PF01048 0.461
MOD_GlcNHglycan 1257 1260 PF01048 0.641
MOD_GlcNHglycan 1267 1270 PF01048 0.509
MOD_GlcNHglycan 140 143 PF01048 0.468
MOD_GlcNHglycan 1460 1463 PF01048 0.325
MOD_GlcNHglycan 1537 1540 PF01048 0.419
MOD_GlcNHglycan 252 255 PF01048 0.380
MOD_GlcNHglycan 417 420 PF01048 0.325
MOD_GlcNHglycan 657 660 PF01048 0.478
MOD_GlcNHglycan 838 841 PF01048 0.347
MOD_GlcNHglycan 848 851 PF01048 0.333
MOD_GlcNHglycan 994 997 PF01048 0.363
MOD_GSK3_1 1094 1101 PF00069 0.436
MOD_GSK3_1 1107 1114 PF00069 0.427
MOD_GSK3_1 1119 1126 PF00069 0.642
MOD_GSK3_1 1140 1147 PF00069 0.588
MOD_GSK3_1 1175 1182 PF00069 0.565
MOD_GSK3_1 1194 1201 PF00069 0.489
MOD_GSK3_1 1204 1211 PF00069 0.586
MOD_GSK3_1 1225 1232 PF00069 0.452
MOD_GSK3_1 1246 1253 PF00069 0.522
MOD_GSK3_1 1318 1325 PF00069 0.379
MOD_GSK3_1 1426 1433 PF00069 0.381
MOD_GSK3_1 1440 1447 PF00069 0.309
MOD_GSK3_1 1450 1457 PF00069 0.328
MOD_GSK3_1 1475 1482 PF00069 0.335
MOD_GSK3_1 1485 1492 PF00069 0.314
MOD_GSK3_1 279 286 PF00069 0.366
MOD_GSK3_1 310 317 PF00069 0.348
MOD_GSK3_1 322 329 PF00069 0.532
MOD_GSK3_1 351 358 PF00069 0.295
MOD_GSK3_1 491 498 PF00069 0.422
MOD_GSK3_1 53 60 PF00069 0.420
MOD_GSK3_1 623 630 PF00069 0.395
MOD_GSK3_1 63 70 PF00069 0.482
MOD_GSK3_1 686 693 PF00069 0.505
MOD_GSK3_1 734 741 PF00069 0.454
MOD_GSK3_1 885 892 PF00069 0.328
MOD_N-GLC_1 1020 1025 PF02516 0.516
MOD_N-GLC_1 259 264 PF02516 0.346
MOD_N-GLC_1 367 372 PF02516 0.416
MOD_N-GLC_1 402 407 PF02516 0.299
MOD_NEK2_1 1 6 PF00069 0.585
MOD_NEK2_1 1032 1037 PF00069 0.540
MOD_NEK2_1 1085 1090 PF00069 0.617
MOD_NEK2_1 1127 1132 PF00069 0.514
MOD_NEK2_1 1203 1208 PF00069 0.508
MOD_NEK2_1 1254 1259 PF00069 0.494
MOD_NEK2_1 1283 1288 PF00069 0.536
MOD_NEK2_1 1301 1306 PF00069 0.342
MOD_NEK2_1 1444 1449 PF00069 0.309
MOD_NEK2_1 1479 1484 PF00069 0.326
MOD_NEK2_1 167 172 PF00069 0.532
MOD_NEK2_1 259 264 PF00069 0.346
MOD_NEK2_1 283 288 PF00069 0.521
MOD_NEK2_1 396 401 PF00069 0.407
MOD_NEK2_1 581 586 PF00069 0.397
MOD_NEK2_1 685 690 PF00069 0.480
MOD_NEK2_1 738 743 PF00069 0.567
MOD_NEK2_1 756 761 PF00069 0.269
MOD_NEK2_1 764 769 PF00069 0.358
MOD_NEK2_1 785 790 PF00069 0.376
MOD_NEK2_1 836 841 PF00069 0.343
MOD_NEK2_1 868 873 PF00069 0.554
MOD_NEK2_1 885 890 PF00069 0.233
MOD_NEK2_1 941 946 PF00069 0.338
MOD_NEK2_1 992 997 PF00069 0.363
MOD_NEK2_2 1107 1112 PF00069 0.486
MOD_NEK2_2 269 274 PF00069 0.361
MOD_NEK2_2 355 360 PF00069 0.278
MOD_PIKK_1 1127 1133 PF00454 0.611
MOD_PIKK_1 12 18 PF00454 0.528
MOD_PIKK_1 1302 1308 PF00454 0.381
MOD_PIKK_1 623 629 PF00454 0.377
MOD_PK_1 1292 1298 PF00069 0.386
MOD_PK_1 639 645 PF00069 0.432
MOD_PKA_1 103 109 PF00069 0.421
MOD_PKA_1 1550 1556 PF00069 0.381
MOD_PKA_1 172 178 PF00069 0.535
MOD_PKA_1 464 470 PF00069 0.420
MOD_PKA_1 67 73 PF00069 0.524
MOD_PKA_2 102 108 PF00069 0.487
MOD_PKA_2 1302 1308 PF00069 0.309
MOD_PKA_2 1309 1315 PF00069 0.309
MOD_PKA_2 1458 1464 PF00069 0.309
MOD_PKA_2 1511 1517 PF00069 0.381
MOD_PKA_2 1550 1556 PF00069 0.309
MOD_PKA_2 172 178 PF00069 0.535
MOD_PKA_2 202 208 PF00069 0.442
MOD_PKA_2 370 376 PF00069 0.345
MOD_PKA_2 63 69 PF00069 0.452
MOD_PKA_2 698 704 PF00069 0.374
MOD_PKA_2 734 740 PF00069 0.364
MOD_PKA_2 836 842 PF00069 0.318
MOD_Plk_1 1020 1026 PF00069 0.519
MOD_Plk_1 116 122 PF00069 0.447
MOD_Plk_1 259 265 PF00069 0.339
MOD_Plk_1 367 373 PF00069 0.440
MOD_Plk_1 444 450 PF00069 0.388
MOD_Plk_1 510 516 PF00069 0.343
MOD_Plk_1 581 587 PF00069 0.397
MOD_Plk_2-3 445 451 PF00069 0.271
MOD_Plk_4 1040 1046 PF00069 0.405
MOD_Plk_4 1095 1101 PF00069 0.368
MOD_Plk_4 1123 1129 PF00069 0.552
MOD_Plk_4 1199 1205 PF00069 0.606
MOD_Plk_4 1347 1353 PF00069 0.241
MOD_Plk_4 1381 1387 PF00069 0.413
MOD_Plk_4 1412 1418 PF00069 0.397
MOD_Plk_4 1556 1562 PF00069 0.468
MOD_Plk_4 259 265 PF00069 0.417
MOD_Plk_4 279 285 PF00069 0.215
MOD_Plk_4 299 305 PF00069 0.339
MOD_Plk_4 3 9 PF00069 0.543
MOD_Plk_4 310 316 PF00069 0.332
MOD_Plk_4 322 328 PF00069 0.360
MOD_Plk_4 396 402 PF00069 0.320
MOD_Plk_4 445 451 PF00069 0.327
MOD_Plk_4 466 472 PF00069 0.370
MOD_Plk_4 53 59 PF00069 0.389
MOD_Plk_4 568 574 PF00069 0.320
MOD_Plk_4 680 686 PF00069 0.346
MOD_Plk_4 759 765 PF00069 0.345
MOD_Plk_4 785 791 PF00069 0.337
MOD_Plk_4 868 874 PF00069 0.542
MOD_Plk_4 885 891 PF00069 0.204
MOD_Plk_4 941 947 PF00069 0.329
MOD_ProDKin_1 1051 1057 PF00069 0.354
MOD_ProDKin_1 1119 1125 PF00069 0.707
MOD_ProDKin_1 1180 1186 PF00069 0.634
MOD_ProDKin_1 1194 1200 PF00069 0.369
MOD_ProDKin_1 135 141 PF00069 0.621
MOD_ProDKin_1 1454 1460 PF00069 0.384
MOD_ProDKin_1 156 162 PF00069 0.482
MOD_ProDKin_1 314 320 PF00069 0.339
MOD_ProDKin_1 351 357 PF00069 0.253
MOD_ProDKin_1 491 497 PF00069 0.451
MOD_ProDKin_1 74 80 PF00069 0.499
MOD_ProDKin_1 933 939 PF00069 0.410
MOD_SUMO_for_1 1421 1424 PF00179 0.381
MOD_SUMO_rev_2 1415 1423 PF00179 0.309
MOD_SUMO_rev_2 175 181 PF00179 0.512
MOD_SUMO_rev_2 561 569 PF00179 0.322
MOD_SUMO_rev_2 61 66 PF00179 0.461
TRG_DiLeu_BaEn_1 1347 1352 PF01217 0.241
TRG_DiLeu_BaEn_1 152 157 PF01217 0.521
TRG_DiLeu_BaEn_1 1556 1561 PF01217 0.520
TRG_DiLeu_BaEn_1 185 190 PF01217 0.506
TRG_DiLeu_BaEn_1 747 752 PF01217 0.404
TRG_DiLeu_BaEn_1 987 992 PF01217 0.388
TRG_DiLeu_LyEn_5 747 752 PF01217 0.404
TRG_ENDOCYTIC_2 1193 1196 PF00928 0.396
TRG_ENDOCYTIC_2 1317 1320 PF00928 0.339
TRG_ENDOCYTIC_2 242 245 PF00928 0.405
TRG_ENDOCYTIC_2 304 307 PF00928 0.430
TRG_ENDOCYTIC_2 327 330 PF00928 0.464
TRG_ENDOCYTIC_2 393 396 PF00928 0.362
TRG_ENDOCYTIC_2 409 412 PF00928 0.381
TRG_ENDOCYTIC_2 556 559 PF00928 0.354
TRG_ENDOCYTIC_2 676 679 PF00928 0.369
TRG_ENDOCYTIC_2 851 854 PF00928 0.346
TRG_ENDOCYTIC_2 932 935 PF00928 0.435
TRG_ER_diArg_1 102 104 PF00400 0.349
TRG_ER_diArg_1 1550 1552 PF00400 0.358
TRG_ER_diArg_1 171 173 PF00400 0.557
TRG_ER_diArg_1 369 372 PF00400 0.397
TRG_ER_diArg_1 431 433 PF00400 0.391
TRG_ER_diArg_1 487 490 PF00400 0.381
TRG_ER_diArg_1 547 549 PF00400 0.288
TRG_ER_diArg_1 961 963 PF00400 0.574
TRG_ER_diArg_1 980 982 PF00400 0.417
TRG_ER_diArg_1 997 999 PF00400 0.262
TRG_NES_CRM1_1 1341 1355 PF08389 0.241
TRG_NLS_MonoExtN_4 531 538 PF00514 0.362
TRG_NLS_MonoExtN_4 998 1003 PF00514 0.302
TRG_Pf-PMV_PEXEL_1 1076 1081 PF00026 0.543
TRG_Pf-PMV_PEXEL_1 1446 1450 PF00026 0.381
TRG_Pf-PMV_PEXEL_1 547 551 PF00026 0.275

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P883 Leptomonas seymouri 49% 100%
A0A3S7XAH3 Leishmania donovani 88% 100%
A4HNV1 Leishmania braziliensis 63% 100%
A4ICP3 Leishmania infantum 88% 100%
E9ASL1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 81% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS