| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 4 |
| Forrest at al. (procyclic) | no | yes: 4 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | yes | yes: 24 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | yes | yes: 5 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 20 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 12 |
| NetGPI | no | yes: 0, no: 12 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005737 | cytoplasm | 2 | 3 |
| GO:0005829 | cytosol | 2 | 3 |
| GO:0015935 | small ribosomal subunit | 4 | 3 |
| GO:0031974 | membrane-enclosed lumen | 2 | 3 |
| GO:0031981 | nuclear lumen | 5 | 3 |
| GO:0032991 | protein-containing complex | 1 | 13 |
| GO:0043233 | organelle lumen | 3 | 3 |
| GO:0044391 | ribosomal subunit | 3 | 3 |
| GO:0070013 | intracellular organelle lumen | 4 | 3 |
| GO:0110165 | cellular anatomical entity | 1 | 13 |
| GO:1990904 | ribonucleoprotein complex | 2 | 13 |
| GO:0005840 | ribosome | 5 | 10 |
| GO:0043226 | organelle | 2 | 10 |
| GO:0043228 | non-membrane-bounded organelle | 3 | 10 |
| GO:0043229 | intracellular organelle | 3 | 10 |
| GO:0043232 | intracellular non-membrane-bounded organelle | 4 | 10 |
Related structures:
AlphaFold database: Q4Q1Y3
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0006412 | translation | 4 | 13 |
| GO:0006518 | peptide metabolic process | 4 | 13 |
| GO:0006807 | nitrogen compound metabolic process | 2 | 13 |
| GO:0008152 | metabolic process | 1 | 13 |
| GO:0009058 | biosynthetic process | 2 | 13 |
| GO:0009059 | macromolecule biosynthetic process | 4 | 13 |
| GO:0009987 | cellular process | 1 | 13 |
| GO:0019538 | protein metabolic process | 3 | 13 |
| GO:0034641 | cellular nitrogen compound metabolic process | 3 | 13 |
| GO:0034645 | obsolete cellular macromolecule biosynthetic process | 4 | 13 |
| GO:0043043 | peptide biosynthetic process | 5 | 13 |
| GO:0043170 | macromolecule metabolic process | 3 | 13 |
| GO:0043603 | amide metabolic process | 3 | 13 |
| GO:0043604 | amide biosynthetic process | 4 | 13 |
| GO:0044237 | cellular metabolic process | 2 | 13 |
| GO:0044238 | primary metabolic process | 2 | 13 |
| GO:0044249 | cellular biosynthetic process | 3 | 13 |
| GO:0044260 | obsolete cellular macromolecule metabolic process | 3 | 13 |
| GO:0044271 | cellular nitrogen compound biosynthetic process | 4 | 13 |
| GO:0071704 | organic substance metabolic process | 2 | 13 |
| GO:1901564 | organonitrogen compound metabolic process | 3 | 13 |
| GO:1901566 | organonitrogen compound biosynthetic process | 4 | 13 |
| GO:1901576 | organic substance biosynthetic process | 3 | 13 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | 3 | 13 |
| GO:0003723 | RNA binding | 4 | 13 |
| GO:0003735 | structural constituent of ribosome | 2 | 13 |
| GO:0005198 | structural molecule activity | 1 | 13 |
| GO:0005488 | binding | 1 | 13 |
| GO:0097159 | organic cyclic compound binding | 2 | 13 |
| GO:1901363 | heterocyclic compound binding | 2 | 13 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_C14_Caspase3-7 | 41 | 45 | PF00656 | 0.442 |
| CLV_NRD_NRD_1 | 120 | 122 | PF00675 | 0.317 |
| CLV_NRD_NRD_1 | 89 | 91 | PF00675 | 0.317 |
| CLV_PCSK_KEX2_1 | 120 | 122 | PF00082 | 0.317 |
| CLV_PCSK_KEX2_1 | 89 | 91 | PF00082 | 0.317 |
| CLV_PCSK_PC1ET2_1 | 89 | 91 | PF00082 | 0.317 |
| CLV_PCSK_SKI1_1 | 97 | 101 | PF00082 | 0.316 |
| DEG_APCC_DBOX_1 | 173 | 181 | PF00400 | 0.517 |
| DEG_APCC_DBOX_1 | 64 | 72 | PF00400 | 0.438 |
| DEG_Nend_Nbox_1 | 1 | 3 | PF02207 | 0.446 |
| DOC_CYCLIN_yClb3_PxF_3 | 7 | 13 | PF00134 | 0.434 |
| DOC_MAPK_gen_1 | 112 | 118 | PF00069 | 0.517 |
| DOC_MAPK_gen_1 | 187 | 197 | PF00069 | 0.517 |
| DOC_MAPK_gen_1 | 97 | 106 | PF00069 | 0.517 |
| DOC_MAPK_MEF2A_6 | 97 | 106 | PF00069 | 0.517 |
| DOC_PP2B_LxvP_1 | 30 | 33 | PF13499 | 0.451 |
| DOC_PP4_FxxP_1 | 143 | 146 | PF00568 | 0.535 |
| DOC_PP4_FxxP_1 | 25 | 28 | PF00568 | 0.443 |
| DOC_USP7_MATH_1 | 64 | 68 | PF00917 | 0.456 |
| DOC_WW_Pin1_4 | 7 | 12 | PF00397 | 0.432 |
| LIG_14-3-3_CanoR_1 | 12 | 16 | PF00244 | 0.447 |
| LIG_14-3-3_CanoR_1 | 207 | 213 | PF00244 | 0.578 |
| LIG_14-3-3_CanoR_1 | 65 | 71 | PF00244 | 0.445 |
| LIG_BRCT_BRCA1_1 | 9 | 13 | PF00533 | 0.437 |
| LIG_FHA_1 | 159 | 165 | PF00498 | 0.517 |
| LIG_FHA_1 | 209 | 215 | PF00498 | 0.583 |
| LIG_FHA_2 | 124 | 130 | PF00498 | 0.526 |
| LIG_FHA_2 | 18 | 24 | PF00498 | 0.445 |
| LIG_FHA_2 | 39 | 45 | PF00498 | 0.444 |
| LIG_FHA_2 | 82 | 88 | PF00498 | 0.517 |
| LIG_LIR_Apic_2 | 23 | 28 | PF02991 | 0.445 |
| LIG_LIR_Gen_1 | 10 | 21 | PF02991 | 0.441 |
| LIG_LIR_Gen_1 | 73 | 82 | PF02991 | 0.478 |
| LIG_LIR_Nem_3 | 10 | 16 | PF02991 | 0.440 |
| LIG_LIR_Nem_3 | 73 | 78 | PF02991 | 0.493 |
| LIG_LYPXL_yS_3 | 63 | 66 | PF13949 | 0.464 |
| LIG_Pex14_2 | 2 | 6 | PF04695 | 0.439 |
| LIG_SH2_STAT5 | 108 | 111 | PF00017 | 0.631 |
| LIG_SH3_3 | 2 | 8 | PF00018 | 0.435 |
| LIG_SH3_3 | 30 | 36 | PF00018 | 0.454 |
| LIG_SH3_3 | 49 | 55 | PF00018 | 0.418 |
| LIG_SUMO_SIM_anti_2 | 67 | 73 | PF11976 | 0.700 |
| LIG_TRAF2_1 | 126 | 129 | PF00917 | 0.535 |
| MOD_CDK_SPK_2 | 7 | 12 | PF00069 | 0.432 |
| MOD_CK2_1 | 123 | 129 | PF00069 | 0.517 |
| MOD_CK2_1 | 81 | 87 | PF00069 | 0.535 |
| MOD_Cter_Amidation | 87 | 90 | PF01082 | 0.317 |
| MOD_GlcNHglycan | 204 | 207 | PF01048 | 0.293 |
| MOD_GlcNHglycan | 48 | 51 | PF01048 | 0.450 |
| MOD_GSK3_1 | 158 | 165 | PF00069 | 0.517 |
| MOD_GSK3_1 | 208 | 215 | PF00069 | 0.608 |
| MOD_GSK3_1 | 7 | 14 | PF00069 | 0.436 |
| MOD_N-GLC_1 | 17 | 22 | PF02516 | 0.443 |
| MOD_NEK2_1 | 164 | 169 | PF00069 | 0.540 |
| MOD_NEK2_1 | 66 | 71 | PF00069 | 0.551 |
| MOD_NEK2_1 | 81 | 86 | PF00069 | 0.523 |
| MOD_PKA_2 | 11 | 17 | PF00069 | 0.439 |
| MOD_PKA_2 | 64 | 70 | PF00069 | 0.448 |
| MOD_Plk_1 | 17 | 23 | PF00069 | 0.444 |
| MOD_Plk_4 | 164 | 170 | PF00069 | 0.594 |
| MOD_Plk_4 | 66 | 72 | PF00069 | 0.650 |
| MOD_ProDKin_1 | 7 | 13 | PF00069 | 0.434 |
| TRG_DiLeu_BaLyEn_6 | 77 | 82 | PF01217 | 0.465 |
| TRG_ENDOCYTIC_2 | 63 | 66 | PF00928 | 0.464 |
| TRG_ER_diArg_1 | 195 | 198 | PF00400 | 0.517 |
| TRG_NLS_MonoExtC_3 | 88 | 93 | PF00514 | 0.511 |
| TRG_NLS_MonoExtN_4 | 179 | 185 | PF00514 | 0.517 |
| TRG_Pf-PMV_PEXEL_1 | 58 | 62 | PF00026 | 0.480 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0S4IKD7 | Bodo saltans | 80% | 100% |
| A0A1X0P911 | Trypanosomatidae | 92% | 100% |
| A0A381MVV3 | Leishmania infantum | 98% | 100% |
| A0A3Q8IJW8 | Leishmania donovani | 98% | 100% |
| A0A3Q8IK98 | Leishmania donovani | 96% | 100% |
| A0A3R7KMU0 | Trypanosoma rangeli | 88% | 100% |
| A1RT04 | Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3) | 37% | 100% |
| A1RWT9 | Thermofilum pendens (strain DSM 2475 / Hrk 5) | 43% | 100% |
| A2BK76 | Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5) | 46% | 100% |
| A3CWH6 | Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) | 37% | 100% |
| A3MUT0 | Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1) | 37% | 100% |
| A4HNV2 | Leishmania braziliensis | 97% | 100% |
| A4ICP1 | Leishmania infantum | 96% | 100% |
| A4WM28 | Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321 / PZ6) | 38% | 100% |
| A5JST6 | Capra hircus | 58% | 100% |
| A5UN52 | Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS) | 43% | 100% |
| D0A2S1 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 88% | 100% |
| E9ASL3 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 99% | 100% |
| O26141 | Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) | 41% | 100% |
| P0CT66 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 64% | 100% |
| P0CT67 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 64% | 100% |
| P34788 | Arabidopsis thaliana | 60% | 100% |
| P41094 | Drosophila melanogaster | 58% | 100% |
| P48151 | Entamoeba histolytica | 59% | 100% |
| P49202 | Chlamydomonas reinhardtii | 59% | 100% |
| P62269 | Homo sapiens | 58% | 100% |
| P62270 | Mus musculus | 58% | 100% |
| P62271 | Rattus norvegicus | 58% | 100% |
| P62272 | Sus scrofa | 58% | 100% |
| P95986 | Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) | 42% | 100% |
| Q0W1V6 | Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50) | 38% | 97% |
| Q12ZR6 | Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M) | 40% | 100% |
| Q2NFZ3 | Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3) | 41% | 100% |
| Q3IQT9 | Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / JCM 8858 / NBRC 14720 / NCIMB 2260 / Gabara) | 36% | 100% |
| Q3T0R1 | Bos taurus | 58% | 100% |
| Q46GC7 | Methanosarcina barkeri (strain Fusaro / DSM 804) | 43% | 100% |
| Q4Q1Y2 | Leishmania major | 100% | 100% |
| Q5JJF1 | Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) | 47% | 100% |
| Q5TJE9 | Canis lupus familiaris | 58% | 100% |
| Q6KZP8 | Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828) | 38% | 100% |
| Q869U7 | Dictyostelium discoideum | 58% | 100% |
| Q8ISP0 | Branchiostoma belcheri | 59% | 100% |
| Q8IT98 | Argopecten irradians | 56% | 100% |
| Q8JGS9 | Danio rerio | 58% | 100% |
| Q8PV19 | Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) | 44% | 100% |
| Q8SRP2 | Encephalitozoon cuniculi (strain GB-M1) | 44% | 100% |
| Q8TRR2 | Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) | 45% | 100% |
| Q8TVC1 | Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938) | 41% | 100% |
| Q8ZTV0 | Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2) | 38% | 100% |
| Q90YQ5 | Ictalurus punctatus | 58% | 100% |
| Q962R1 | Spodoptera frugiperda | 62% | 100% |