Intraflagellar transport protein 122 homolog

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

intraflagellar transport protein 122, putative

Species:

Leishmania major

UniProt:

Q4Q1X6_LEIMA

TriTrypDb:

LmjF.36.1000 , LMJLV39_360015700 , LMJSD75_360015700

Length:

1296

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 8

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

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Cellular components
Term	Name	Level	Count
GO:0005815	microtubule organizing center	2	2
GO:0005929	cilium	4	12
GO:0030990	intraciliary transport particle	2	2
GO:0030991	intraciliary transport particle A	2	2
GO:0031514	motile cilium	5	2
GO:0032991	protein-containing complex	1	2
GO:0036064	ciliary basal body	3	2
GO:0042995	cell projection	2	12
GO:0043226	organelle	2	12
GO:0043227	membrane-bounded organelle	3	12

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Expansion

Sequence features

Q4Q1X6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

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Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	2
GO:0006996	organelle organization	4	12
GO:0007017	microtubule-based process	2	2
GO:0007018	microtubule-based movement	3	2
GO:0008104	protein localization	4	2
GO:0009987	cellular process	1	12
GO:0010970	transport along microtubule	4	2
GO:0016043	cellular component organization	3	12
GO:0022607	cellular component assembly	4	12
GO:0030030	cell projection organization	4	12

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Could not find GO molecular_function term for this entry.

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1118	1122	PF00656	0.653
CLV_C14_Caspase3-7	515	519	PF00656	0.503
CLV_C14_Caspase3-7	9	13	PF00656	0.495
CLV_NRD_NRD_1	1104	1106	PF00675	0.510
CLV_NRD_NRD_1	1203	1205	PF00675	0.367
CLV_NRD_NRD_1	308	310	PF00675	0.450
CLV_NRD_NRD_1	323	325	PF00675	0.307
CLV_NRD_NRD_1	375	377	PF00675	0.345
CLV_NRD_NRD_1	395	397	PF00675	0.148
CLV_NRD_NRD_1	407	409	PF00675	0.336

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5R4	Leptomonas seymouri	79%	100%
A0A0S4J7A2	Bodo saltans	51%	100%
A0A1X0P826	Trypanosomatidae	57%	100%
A0A3S7XAI4	Leishmania donovani	96%	100%
A0A422NTZ2	Trypanosoma rangeli	56%	100%
A4HNV9	Leishmania braziliensis	87%	100%
A4ICN4	Leishmania infantum	96%	100%
A8WGF4	Xenopus tropicalis	36%	100%
D0A2S8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	52%	100%
E9ASM0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%

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