LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q1V7_LEIMA
TriTrypDb:
LmjF.36.1190 , LMJLV39_360017700 , LMJSD75_360017800
Length:
140

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q1V7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q1V7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 122 124 PF00675 0.564
CLV_NRD_NRD_1 2 4 PF00675 0.503
CLV_NRD_NRD_1 66 68 PF00675 0.576
CLV_PCSK_KEX2_1 122 124 PF00082 0.539
CLV_PCSK_KEX2_1 2 4 PF00082 0.503
CLV_PCSK_SKI1_1 118 122 PF00082 0.653
CLV_PCSK_SKI1_1 2 6 PF00082 0.635
CLV_PCSK_SKI1_1 35 39 PF00082 0.717
DEG_Nend_UBRbox_1 1 4 PF02207 0.510
DEG_SCF_FBW7_1 19 24 PF00400 0.638
DOC_MAPK_gen_1 2 10 PF00069 0.502
DOC_WW_Pin1_4 17 22 PF00397 0.569
LIG_APCC_ABBA_1 94 99 PF00400 0.495
LIG_BRCT_BRCA1_1 128 132 PF00533 0.580
LIG_FHA_2 42 48 PF00498 0.500
LIG_LIR_Gen_1 79 86 PF02991 0.523
LIG_LIR_Nem_3 79 83 PF02991 0.529
LIG_SH2_GRB2like 40 43 PF00017 0.516
LIG_SH2_NCK_1 97 101 PF00017 0.558
LIG_SH2_SRC 80 83 PF00017 0.527
LIG_SH2_STAP1 103 107 PF00017 0.546
LIG_SH2_STAT3 109 112 PF00017 0.538
LIG_SH2_STAT5 40 43 PF00017 0.713
LIG_SH2_STAT5 82 85 PF00017 0.493
LIG_TRAF2_1 44 47 PF00917 0.464
MOD_CDK_SPxK_1 17 23 PF00069 0.637
MOD_CK2_1 41 47 PF00069 0.504
MOD_GlcNHglycan 126 131 PF01048 0.584
MOD_GSK3_1 17 24 PF00069 0.580
MOD_GSK3_1 41 48 PF00069 0.546
MOD_GSK3_1 52 59 PF00069 0.645
MOD_N-GLC_1 41 46 PF02516 0.505
MOD_PK_1 52 58 PF00069 0.456
MOD_Plk_1 41 47 PF00069 0.504
MOD_Plk_1 69 75 PF00069 0.513
MOD_ProDKin_1 17 23 PF00069 0.571
MOD_SUMO_rev_2 46 50 PF00179 0.519
TRG_DiLeu_BaEn_4 69 75 PF01217 0.513
TRG_ENDOCYTIC_2 111 114 PF00928 0.514
TRG_ENDOCYTIC_2 80 83 PF00928 0.527
TRG_ER_diArg_1 1 3 PF00400 0.517
TRG_ER_diArg_1 64 67 PF00400 0.557

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I3V3 Leptomonas seymouri 82% 100%
A0A0S4J8Z0 Bodo saltans 52% 100%
A0A1X0P9F9 Trypanosomatidae 74% 98%
A0A3Q8ING9 Leishmania donovani 94% 100%
A4HNX9 Leishmania braziliensis 89% 100%
A4ICL5 Leishmania infantum 94% 100%
D0A2U5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 81% 100%
E9ASN9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%
V5BUX9 Trypanosoma cruzi 70% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS