Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q1U7_LEIMA

TriTrypDb:

LmjF.36.1290 , LMJLV39_360018600 , LMJSD75_360018600

Length:

344

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q1U7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q1U7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	127	129	PF00675	0.412
CLV_NRD_NRD_1	175	177	PF00675	0.365
CLV_NRD_NRD_1	181	183	PF00675	0.390
CLV_NRD_NRD_1	262	264	PF00675	0.352
CLV_NRD_NRD_1	272	274	PF00675	0.391
CLV_NRD_NRD_1	59	61	PF00675	0.352
CLV_NRD_NRD_1	73	75	PF00675	0.362
CLV_PCSK_KEX2_1	127	129	PF00082	0.412
CLV_PCSK_KEX2_1	163	165	PF00082	0.406
CLV_PCSK_KEX2_1	175	177	PF00082	0.365
CLV_PCSK_KEX2_1	181	183	PF00082	0.390
CLV_PCSK_KEX2_1	196	198	PF00082	0.360
CLV_PCSK_KEX2_1	254	256	PF00082	0.368
CLV_PCSK_KEX2_1	272	274	PF00082	0.391
CLV_PCSK_KEX2_1	308	310	PF00082	0.341
CLV_PCSK_KEX2_1	59	61	PF00082	0.352
CLV_PCSK_KEX2_1	73	75	PF00082	0.362
CLV_PCSK_PC1ET2_1	163	165	PF00082	0.406
CLV_PCSK_PC1ET2_1	196	198	PF00082	0.360
CLV_PCSK_PC1ET2_1	254	256	PF00082	0.368
CLV_PCSK_PC1ET2_1	308	310	PF00082	0.341
CLV_PCSK_SKI1_1	127	131	PF00082	0.411
CLV_PCSK_SKI1_1	163	167	PF00082	0.383
CLV_PCSK_SKI1_1	175	179	PF00082	0.357
CLV_PCSK_SKI1_1	254	258	PF00082	0.361
CLV_PCSK_SKI1_1	46	50	PF00082	0.346
DEG_ODPH_VHL_1	82	95	PF01847	0.363
DOC_CYCLIN_yCln2_LP_2	186	192	PF00134	0.396
DOC_MAPK_gen_1	127	134	PF00069	0.419
DOC_MAPK_RevD_3	149	164	PF00069	0.412
DOC_MAPK_RevD_3	290	304	PF00069	0.323
DOC_PP2B_LxvP_1	177	180	PF13499	0.357
DOC_PP4_FxxP_1	133	136	PF00568	0.429
DOC_USP7_MATH_1	112	116	PF00917	0.337
DOC_USP7_UBL2_3	304	308	PF12436	0.332
DOC_WW_Pin1_4	196	201	PF00397	0.349
DOC_WW_Pin1_4	239	244	PF00397	0.422
DOC_WW_Pin1_4	65	70	PF00397	0.372
LIG_14-3-3_CanoR_1	142	152	PF00244	0.407
LIG_14-3-3_CanoR_1	175	180	PF00244	0.359
LIG_14-3-3_CanoR_1	205	211	PF00244	0.336
LIG_14-3-3_CanoR_1	30	40	PF00244	0.429
LIG_14-3-3_CanoR_1	59	65	PF00244	0.364
LIG_AP2alpha_2	188	190	PF02296	0.393
LIG_BRCT_BRCA1_1	109	113	PF00533	0.363
LIG_BRCT_BRCA1_1	50	54	PF00533	0.286
LIG_FHA_1	193	199	PF00498	0.372
LIG_FHA_1	205	211	PF00498	0.336
LIG_FHA_1	320	326	PF00498	0.405
LIG_FHA_2	164	170	PF00498	0.359
LIG_FHA_2	264	270	PF00498	0.351
LIG_FHA_2	83	89	PF00498	0.371
LIG_LIR_Apic_2	130	136	PF02991	0.424
LIG_LIR_Apic_2	312	317	PF02991	0.343
LIG_LIR_Gen_1	88	95	PF02991	0.372
LIG_LIR_Gen_1	9	17	PF02991	0.404
LIG_LIR_Nem_3	53	58	PF02991	0.312
LIG_LIR_Nem_3	86	92	PF02991	0.385
LIG_LIR_Nem_3	9	15	PF02991	0.401
LIG_Pex14_1	116	120	PF04695	0.343
LIG_Pex14_2	48	52	PF04695	0.309
LIG_SH2_CRK	277	281	PF00017	0.421
LIG_SH2_STAP1	156	160	PF00017	0.415
LIG_SH2_STAP1	211	215	PF00017	0.330
LIG_SH2_STAP1	311	315	PF00017	0.340
LIG_SH2_STAT5	211	214	PF00017	0.332
LIG_SH2_STAT5	314	317	PF00017	0.345
LIG_SH3_1	240	246	PF00018	0.396
LIG_SH3_3	103	109	PF00018	0.413
LIG_SH3_3	240	246	PF00018	0.396
LIG_SH3_3	63	69	PF00018	0.372
LIG_SUMO_SIM_par_1	91	96	PF11976	0.359
LIG_WRC_WIRS_1	49	54	PF05994	0.290
MOD_CK1_1	10	16	PF00069	0.398
MOD_CK1_1	204	210	PF00069	0.332
MOD_CK1_1	242	248	PF00069	0.370
MOD_CK1_1	36	42	PF00069	0.370
MOD_CK1_1	50	56	PF00069	0.285
MOD_CK1_1	96	102	PF00069	0.372
MOD_CK2_1	263	269	PF00069	0.350
MOD_Cter_Amidation	161	164	PF01082	0.415
MOD_DYRK1A_RPxSP_1	65	69	PF00069	0.378
MOD_GlcNHglycan	145	148	PF01048	0.400
MOD_GlcNHglycan	35	38	PF01048	0.433
MOD_GSK3_1	192	199	PF00069	0.378
MOD_GSK3_1	29	36	PF00069	0.458
MOD_GSK3_1	3	10	PF00069	0.432
MOD_GSK3_1	315	322	PF00069	0.370
MOD_GSK3_1	50	57	PF00069	0.293
MOD_LATS_1	173	179	PF00433	0.352
MOD_N-GLC_1	281	286	PF02516	0.398
MOD_NEK2_1	310	315	PF00069	0.339
MOD_NEK2_1	33	38	PF00069	0.441
MOD_NEK2_1	337	342	PF00069	0.435
MOD_NEK2_1	48	53	PF00069	0.305
MOD_NEK2_1	54	59	PF00069	0.321
MOD_NEK2_1	91	96	PF00069	0.359
MOD_PIKK_1	209	215	PF00454	0.334
MOD_PK_1	60	66	PF00069	0.361
MOD_PKA_1	127	133	PF00069	0.418
MOD_PKA_1	163	169	PF00069	0.371
MOD_PKA_1	175	181	PF00069	0.364
MOD_PKA_1	263	269	PF00069	0.350
MOD_PKA_1	303	309	PF00069	0.335
MOD_PKA_2	127	133	PF00069	0.418
MOD_PKA_2	163	169	PF00069	0.371
MOD_PKA_2	175	181	PF00069	0.364
MOD_PKA_2	204	210	PF00069	0.332
MOD_PKA_2	234	240	PF00069	0.436
MOD_PKA_2	278	284	PF00069	0.410
MOD_PKA_2	29	35	PF00069	0.459
MOD_Plk_1	10	16	PF00069	0.398
MOD_Plk_1	156	162	PF00069	0.414
MOD_Plk_1	249	255	PF00069	0.350
MOD_Plk_4	112	118	PF00069	0.333
MOD_Plk_4	134	140	PF00069	0.423
MOD_Plk_4	234	240	PF00069	0.436
MOD_Plk_4	310	316	PF00069	0.336
MOD_ProDKin_1	196	202	PF00069	0.343
MOD_ProDKin_1	239	245	PF00069	0.410
MOD_ProDKin_1	65	71	PF00069	0.368
MOD_SUMO_rev_2	259	266	PF00179	0.341
TRG_ENDOCYTIC_2	297	300	PF00928	0.327
TRG_ER_diArg_1	126	128	PF00400	0.398
TRG_ER_diArg_1	174	176	PF00400	0.352
TRG_ER_diArg_1	180	182	PF00400	0.385
TRG_ER_diArg_1	271	273	PF00400	0.385
TRG_ER_diArg_1	58	60	PF00400	0.359
TRG_ER_diArg_1	64	67	PF00400	0.361
TRG_NES_CRM1_1	47	62	PF08389	0.326

Homologs


Protein	Taxonomy	Sequence identity	Coverage
P17960	TRYBB	34%	100%