Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q1S5_LEIMA

TriTrypDb:

LmjF.36.1510 , LMJLV39_360021200 , LMJSD75_360021200

Length:

174

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q1S5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q1S5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	88	92	PF00656	0.381
CLV_NRD_NRD_1	138	140	PF00675	0.449
CLV_NRD_NRD_1	14	16	PF00675	0.551
CLV_NRD_NRD_1	38	40	PF00675	0.582
CLV_PCSK_KEX2_1	13	15	PF00082	0.545
CLV_PCSK_KEX2_1	38	40	PF00082	0.583
CLV_PCSK_KEX2_1	64	66	PF00082	0.729
CLV_PCSK_PC1ET2_1	64	66	PF00082	0.729
CLV_PCSK_SKI1_1	158	162	PF00082	0.466
CLV_PCSK_SKI1_1	78	82	PF00082	0.535
DEG_Nend_Nbox_1	1	3	PF02207	0.578
DOC_CKS1_1	72	77	PF01111	0.577
DOC_MAPK_gen_1	13	24	PF00069	0.548
DOC_MAPK_gen_1	148	157	PF00069	0.425
DOC_MAPK_MEF2A_6	13	22	PF00069	0.495
DOC_USP7_MATH_1	103	107	PF00917	0.386
DOC_USP7_MATH_1	41	45	PF00917	0.562
DOC_WW_Pin1_4	71	76	PF00397	0.602
LIG_14-3-3_CanoR_1	45	53	PF00244	0.490
LIG_14-3-3_CanoR_1	78	86	PF00244	0.412
LIG_DLG_GKlike_1	129	137	PF00625	0.419
LIG_FHA_1	121	127	PF00498	0.550
LIG_FHA_1	67	73	PF00498	0.497
LIG_FHA_2	140	146	PF00498	0.587
LIG_FHA_2	72	78	PF00498	0.542
LIG_FHA_2	79	85	PF00498	0.465
LIG_Rb_pABgroove_1	147	155	PF01858	0.429
LIG_RPA_C_Fungi	34	46	PF08784	0.480
LIG_SH2_STAP1	153	157	PF00017	0.453
LIG_SH2_STAT5	111	114	PF00017	0.432
LIG_SH2_STAT5	36	39	PF00017	0.667
LIG_SH3_3	26	32	PF00018	0.500
LIG_TRAF2_1	142	145	PF00917	0.454
LIG_WRC_WIRS_1	90	95	PF05994	0.376
MOD_CDK_SPxxK_3	71	78	PF00069	0.604
MOD_CK1_1	106	112	PF00069	0.431
MOD_CK1_1	44	50	PF00069	0.543
MOD_CK1_1	52	58	PF00069	0.497
MOD_CK2_1	139	145	PF00069	0.624
MOD_CK2_1	71	77	PF00069	0.703
MOD_CK2_1	78	84	PF00069	0.508
MOD_CK2_1	89	95	PF00069	0.314
MOD_GlcNHglycan	10	13	PF01048	0.545
MOD_GSK3_1	103	110	PF00069	0.418
MOD_GSK3_1	4	11	PF00069	0.451
MOD_GSK3_1	40	47	PF00069	0.583
MOD_GSK3_1	52	59	PF00069	0.482
MOD_GSK3_1	67	74	PF00069	0.561
MOD_N-GLC_1	4	9	PF02516	0.537
MOD_NEK2_1	89	94	PF00069	0.391
MOD_PKA_1	139	145	PF00069	0.403
MOD_PKA_2	16	22	PF00069	0.522
MOD_PKA_2	44	50	PF00069	0.549
MOD_Plk_4	107	113	PF00069	0.453
MOD_ProDKin_1	71	77	PF00069	0.605
MOD_SUMO_for_1	160	163	PF00179	0.458
MOD_SUMO_rev_2	132	142	PF00179	0.438
MOD_SUMO_rev_2	98	106	PF00179	0.449
TRG_DiLeu_BaEn_1	95	100	PF01217	0.375
TRG_ER_diArg_1	13	15	PF00400	0.556
TRG_ER_diArg_1	37	39	PF00400	0.580

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IJJ7	Leptomonas seymouri	54%	100%
A0A3Q8IQR8	Leishmania donovani	88%	100%
A4HP11	Leishmania braziliensis	69%	100%
A4IDC0	Leishmania infantum	88%	100%
E9ASS1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%