MORN repeat family protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

MORN repeat, putative

Species:

Leishmania major

UniProt:

Q4Q1P3_LEIMA

TriTrypDb:

LmjF.36.1810 , LMJLV39_360024600 , LMJSD75_360024700

Length:

938

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0005930	axoneme	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4Q1P3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q1P3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	231	235	PF00656	0.441
CLV_C14_Caspase3-7	412	416	PF00656	0.410
CLV_C14_Caspase3-7	501	505	PF00656	0.342
CLV_C14_Caspase3-7	600	604	PF00656	0.405
CLV_C14_Caspase3-7	694	698	PF00656	0.240
CLV_C14_Caspase3-7	707	711	PF00656	0.248
CLV_C14_Caspase3-7	775	779	PF00656	0.379
CLV_C14_Caspase3-7	811	815	PF00656	0.498
CLV_C14_Caspase3-7	920	924	PF00656	0.320
CLV_NRD_NRD_1	459	461	PF00675	0.306
CLV_NRD_NRD_1	467	469	PF00675	0.306
CLV_NRD_NRD_1	506	508	PF00675	0.306
CLV_NRD_NRD_1	732	734	PF00675	0.371
CLV_NRD_NRD_1	823	825	PF00675	0.597
CLV_PCSK_KEX2_1	459	461	PF00082	0.306
CLV_PCSK_KEX2_1	467	469	PF00082	0.306
CLV_PCSK_KEX2_1	506	508	PF00082	0.342
CLV_PCSK_KEX2_1	648	650	PF00082	0.306
CLV_PCSK_KEX2_1	732	734	PF00082	0.371
CLV_PCSK_KEX2_1	823	825	PF00082	0.597
CLV_PCSK_PC1ET2_1	648	650	PF00082	0.297
CLV_PCSK_SKI1_1	141	145	PF00082	0.542
CLV_PCSK_SKI1_1	155	159	PF00082	0.639
CLV_PCSK_SKI1_1	182	186	PF00082	0.536
CLV_PCSK_SKI1_1	7	11	PF00082	0.576
CLV_PCSK_SKI1_1	74	78	PF00082	0.386
DEG_APCC_DBOX_1	13	21	PF00400	0.633
DEG_SPOP_SBC_1	377	381	PF00917	0.575
DEG_SPOP_SBC_1	386	390	PF00917	0.453
DEG_SPOP_SBC_1	8	12	PF00917	0.659
DOC_ANK_TNKS_1	489	496	PF00023	0.435
DOC_CDC14_PxL_1	191	199	PF14671	0.602
DOC_CYCLIN_yCln2_LP_2	56	62	PF00134	0.414
DOC_MAPK_gen_1	138	148	PF00069	0.490
DOC_PP1_RVXF_1	325	331	PF00149	0.534
DOC_USP7_MATH_1	175	179	PF00917	0.620
DOC_USP7_MATH_1	212	216	PF00917	0.608
DOC_USP7_MATH_1	219	223	PF00917	0.590
DOC_USP7_MATH_1	23	27	PF00917	0.532
DOC_USP7_MATH_1	346	350	PF00917	0.619
DOC_USP7_MATH_1	354	358	PF00917	0.603
DOC_USP7_MATH_1	377	381	PF00917	0.636
DOC_USP7_MATH_1	45	49	PF00917	0.495
DOC_USP7_MATH_1	671	675	PF00917	0.464
DOC_USP7_MATH_1	8	12	PF00917	0.678
DOC_USP7_MATH_1	815	819	PF00917	0.535
DOC_USP7_MATH_1	827	831	PF00917	0.470
DOC_USP7_MATH_1	898	902	PF00917	0.474
DOC_USP7_MATH_2	244	250	PF00917	0.609
DOC_WW_Pin1_4	171	176	PF00397	0.599
DOC_WW_Pin1_4	318	323	PF00397	0.571
DOC_WW_Pin1_4	362	367	PF00397	0.662
DOC_WW_Pin1_4	378	383	PF00397	0.565
DOC_WW_Pin1_4	489	494	PF00397	0.482
DOC_WW_Pin1_4	669	674	PF00397	0.510
DOC_WW_Pin1_4	94	99	PF00397	0.468
LIG_14-3-3_CanoR_1	301	310	PF00244	0.548
LIG_14-3-3_CanoR_1	692	700	PF00244	0.371
LIG_14-3-3_CanoR_1	7	17	PF00244	0.637
LIG_14-3-3_CanoR_1	869	878	PF00244	0.371
LIG_BIR_II_1	1	5	PF00653	0.579
LIG_BIR_III_2	814	818	PF00653	0.554
LIG_BRCT_BRCA1_1	33	37	PF00533	0.694
LIG_BRCT_BRCA1_1	923	927	PF00533	0.297
LIG_Clathr_ClatBox_2	309	314	PF01394	0.569
LIG_CtBP_PxDLS_1	322	326	PF00389	0.537
LIG_deltaCOP1_diTrp_1	470	478	PF00928	0.306
LIG_EH_1	34	38	PF12763	0.582
LIG_FHA_1	115	121	PF00498	0.384
LIG_FHA_1	373	379	PF00498	0.616
LIG_FHA_1	741	747	PF00498	0.439
LIG_FHA_1	805	811	PF00498	0.542
LIG_FHA_2	148	154	PF00498	0.598
LIG_FHA_2	257	263	PF00498	0.577
LIG_FHA_2	27	33	PF00498	0.614
LIG_FHA_2	319	325	PF00498	0.539
LIG_FHA_2	387	393	PF00498	0.533
LIG_FHA_2	408	414	PF00498	0.400
LIG_FHA_2	558	564	PF00498	0.432
LIG_FHA_2	692	698	PF00498	0.371
LIG_FHA_2	918	924	PF00498	0.334
LIG_Integrin_RGD_1	229	231	PF01839	0.371
LIG_LIR_Apic_2	312	317	PF02991	0.582
LIG_LIR_Apic_2	603	609	PF02991	0.371
LIG_LIR_Apic_2	80	86	PF02991	0.423
LIG_LIR_Nem_3	273	277	PF02991	0.551
LIG_LIR_Nem_3	415	420	PF02991	0.529
LIG_LIR_Nem_3	48	54	PF02991	0.429
LIG_LIR_Nem_3	542	547	PF02991	0.387
LIG_LIR_Nem_3	747	751	PF02991	0.413
LIG_PDZ_Class_2	933	938	PF00595	0.420
LIG_Pex14_2	143	147	PF04695	0.549
LIG_Pex14_2	330	334	PF04695	0.579
LIG_Pex14_2	78	82	PF04695	0.401
LIG_Pex14_2	927	931	PF04695	0.388
LIG_PTB_Apo_2	930	937	PF02174	0.419
LIG_PTB_Phospho_1	930	936	PF10480	0.419
LIG_SH2_NCK_1	241	245	PF00017	0.579
LIG_SH2_PTP2	606	609	PF00017	0.306
LIG_SH2_SRC	124	127	PF00017	0.507
LIG_SH2_SRC	812	815	PF00017	0.546
LIG_SH2_STAT3	474	477	PF00017	0.306
LIG_SH2_STAT3	652	655	PF00017	0.327
LIG_SH2_STAT5	113	116	PF00017	0.482
LIG_SH2_STAT5	124	127	PF00017	0.443
LIG_SH2_STAT5	224	227	PF00017	0.306
LIG_SH2_STAT5	451	454	PF00017	0.331
LIG_SH2_STAT5	51	54	PF00017	0.435
LIG_SH2_STAT5	606	609	PF00017	0.306
LIG_SH2_STAT5	640	643	PF00017	0.306
LIG_SH2_STAT5	772	775	PF00017	0.469
LIG_SH2_STAT5	812	815	PF00017	0.546
LIG_SH2_STAT5	832	835	PF00017	0.306
LIG_SH3_1	418	424	PF00018	0.482
LIG_SH3_3	102	108	PF00018	0.424
LIG_SH3_3	189	195	PF00018	0.589
LIG_SH3_3	290	296	PF00018	0.618
LIG_SH3_3	30	36	PF00018	0.670
LIG_SH3_3	380	386	PF00018	0.637
LIG_SH3_3	418	424	PF00018	0.461
LIG_SH3_3	654	660	PF00018	0.515
LIG_SH3_3	663	669	PF00018	0.553
LIG_SUMO_SIM_par_1	374	381	PF11976	0.535
LIG_TRAF2_1	150	153	PF00917	0.559
LIG_TRAF2_1	243	246	PF00917	0.598
LIG_TRAF2_1	321	324	PF00917	0.525
LIG_TRAF2_1	581	584	PF00917	0.349
LIG_TYR_ITIM	49	54	PF00017	0.414
LIG_TYR_ITIM	746	751	PF00017	0.421
LIG_UBA3_1	247	255	PF00899	0.575
LIG_WW_3	659	663	PF00397	0.515
MOD_CK1_1	12	18	PF00069	0.636
MOD_CK1_1	128	134	PF00069	0.535
MOD_CK1_1	2	8	PF00069	0.645
MOD_CK1_1	249	255	PF00069	0.605
MOD_CK1_1	26	32	PF00069	0.715
MOD_CK1_1	312	318	PF00069	0.593
MOD_CK1_1	50	56	PF00069	0.481
MOD_CK1_1	638	644	PF00069	0.328
MOD_CK1_1	759	765	PF00069	0.431
MOD_CK2_1	147	153	PF00069	0.594
MOD_CK2_1	256	262	PF00069	0.581
MOD_CK2_1	318	324	PF00069	0.541
MOD_CK2_1	386	392	PF00069	0.563
MOD_CK2_1	407	413	PF00069	0.392
MOD_CK2_1	719	725	PF00069	0.459
MOD_CK2_1	850	856	PF00069	0.306
MOD_CMANNOS	311	314	PF00535	0.582
MOD_Cter_Amidation	457	460	PF01082	0.306
MOD_Cter_Amidation	504	507	PF01082	0.342
MOD_GlcNHglycan	126	130	PF01048	0.567
MOD_GlcNHglycan	177	180	PF01048	0.651
MOD_GlcNHglycan	20	23	PF01048	0.598
MOD_GlcNHglycan	203	206	PF01048	0.620
MOD_GlcNHglycan	208	211	PF01048	0.607
MOD_GlcNHglycan	214	217	PF01048	0.541
MOD_GlcNHglycan	311	314	PF01048	0.588
MOD_GlcNHglycan	356	359	PF01048	0.562
MOD_GlcNHglycan	401	404	PF01048	0.504
MOD_GlcNHglycan	509	512	PF01048	0.333
MOD_GlcNHglycan	632	635	PF01048	0.435
MOD_GlcNHglycan	649	652	PF01048	0.318
MOD_GlcNHglycan	687	690	PF01048	0.336
MOD_GlcNHglycan	740	743	PF01048	0.306
MOD_GlcNHglycan	816	820	PF01048	0.537
MOD_GlcNHglycan	873	876	PF01048	0.321
MOD_GSK3_1	147	154	PF00069	0.577
MOD_GSK3_1	164	171	PF00069	0.684
MOD_GSK3_1	208	215	PF00069	0.588
MOD_GSK3_1	312	319	PF00069	0.602
MOD_GSK3_1	344	351	PF00069	0.672
MOD_GSK3_1	364	371	PF00069	0.559
MOD_GSK3_1	372	379	PF00069	0.642
MOD_GSK3_1	50	57	PF00069	0.493
MOD_GSK3_1	507	514	PF00069	0.356
MOD_GSK3_1	557	564	PF00069	0.440
MOD_GSK3_1	715	722	PF00069	0.542
MOD_GSK3_1	740	747	PF00069	0.409
MOD_GSK3_1	755	762	PF00069	0.425
MOD_GSK3_1	8	15	PF00069	0.620
MOD_GSK3_1	917	924	PF00069	0.300
MOD_LATS_1	754	760	PF00433	0.447
MOD_N-GLC_1	18	23	PF02516	0.626
MOD_N-GLC_1	256	261	PF02516	0.540
MOD_NEK2_1	1	6	PF00069	0.687
MOD_NEK2_1	18	23	PF00069	0.565
MOD_NEK2_1	201	206	PF00069	0.652
MOD_NEK2_1	208	213	PF00069	0.557
MOD_NEK2_1	248	253	PF00069	0.652
MOD_NEK2_1	261	266	PF00069	0.571
MOD_NEK2_1	334	339	PF00069	0.579
MOD_NEK2_1	372	377	PF00069	0.653
MOD_NEK2_1	447	452	PF00069	0.373
MOD_NEK2_1	77	82	PF00069	0.385
MOD_NEK2_2	114	119	PF00069	0.397
MOD_NEK2_2	219	224	PF00069	0.634
MOD_NEK2_2	898	903	PF00069	0.400
MOD_NEK2_2	922	927	PF00069	0.334
MOD_OFUCOSY	75	81	PF10250	0.369
MOD_PIKK_1	23	29	PF00454	0.606
MOD_PIKK_1	279	285	PF00454	0.640
MOD_PIKK_1	54	60	PF00454	0.484
MOD_PIKK_1	561	567	PF00454	0.503
MOD_PIKK_1	740	746	PF00454	0.393
MOD_PIKK_1	843	849	PF00454	0.306
MOD_PK_1	756	762	PF00069	0.435
MOD_PK_1	850	856	PF00069	0.306
MOD_PKA_2	206	212	PF00069	0.619
MOD_PKA_2	691	697	PF00069	0.371
MOD_PKA_2	715	721	PF00069	0.465
MOD_PKA_2	755	761	PF00069	0.483
MOD_PKA_2	868	874	PF00069	0.306
MOD_Plk_1	261	267	PF00069	0.627
MOD_Plk_1	368	374	PF00069	0.627
MOD_Plk_1	447	453	PF00069	0.406
MOD_Plk_1	922	928	PF00069	0.335
MOD_Plk_2-3	408	414	PF00069	0.446
MOD_Plk_2-3	540	546	PF00069	0.397
MOD_Plk_4	196	202	PF00069	0.520
MOD_Plk_4	219	225	PF00069	0.589
MOD_Plk_4	26	32	PF00069	0.626
MOD_Plk_4	47	53	PF00069	0.508
MOD_Plk_4	602	608	PF00069	0.396
MOD_Plk_4	635	641	PF00069	0.403
MOD_Plk_4	719	725	PF00069	0.424
MOD_Plk_4	735	741	PF00069	0.306
MOD_Plk_4	772	778	PF00069	0.372
MOD_Plk_4	850	856	PF00069	0.306
MOD_Plk_4	898	904	PF00069	0.557
MOD_Plk_4	922	928	PF00069	0.306
MOD_ProDKin_1	171	177	PF00069	0.599
MOD_ProDKin_1	318	324	PF00069	0.564
MOD_ProDKin_1	362	368	PF00069	0.661
MOD_ProDKin_1	378	384	PF00069	0.565
MOD_ProDKin_1	489	495	PF00069	0.481
MOD_ProDKin_1	669	675	PF00069	0.500
MOD_ProDKin_1	94	100	PF00069	0.468
TRG_DiLeu_BaEn_2	460	466	PF01217	0.327
TRG_DiLeu_BaEn_4	323	329	PF01217	0.510
TRG_DiLeu_BaLyEn_6	91	96	PF01217	0.457
TRG_ENDOCYTIC_2	444	447	PF00928	0.287
TRG_ENDOCYTIC_2	51	54	PF00928	0.418
TRG_ENDOCYTIC_2	544	547	PF00928	0.392
TRG_ENDOCYTIC_2	748	751	PF00928	0.410
TRG_ER_diArg_1	14	17	PF00400	0.568
TRG_ER_diArg_1	466	468	PF00400	0.306
TRG_ER_diArg_1	532	535	PF00400	0.371
TRG_ER_diArg_1	822	824	PF00400	0.594

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I572	Leptomonas seymouri	55%	98%
A0A3S7XAW7	Leishmania donovani	91%	100%
A4HP45	Leishmania braziliensis	79%	100%
A4IDF2	Leishmania infantum	91%	100%
E9ALQ3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	76%
E9ASV3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%