Putative DEAD box RNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DEAD box RNA helicase, putative

Species:

Leishmania major

UniProt:

Q4Q1P0_LEIMA

TriTrypDb:

LmjF.36.1840 , LMJLV39_360024900 , LMJSD75_360025000

Length:

657

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	2
GO:0043226	organelle	2	2
GO:0043228	non-membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043232	intracellular non-membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4Q1P0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q1P0

Function

Biological processes
Term	Name	Level	Count
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	10	2
GO:0000470	maturation of LSU-rRNA	9	2
GO:0006139	nucleobase-containing compound metabolic process	3	2
GO:0006364	rRNA processing	8	2
GO:0006396	RNA processing	6	2
GO:0006725	cellular aromatic compound metabolic process	3	2
GO:0006807	nitrogen compound metabolic process	2	2
GO:0008152	metabolic process	1	2
GO:0009987	cellular process	1	2
GO:0016070	RNA metabolic process	5	2
GO:0016072	rRNA metabolic process	7	2
GO:0034470	ncRNA processing	7	2
GO:0034641	cellular nitrogen compound metabolic process	3	2
GO:0034660	ncRNA metabolic process	6	2
GO:0043170	macromolecule metabolic process	3	2
GO:0044237	cellular metabolic process	2	2
GO:0044238	primary metabolic process	2	2
GO:0046483	heterocycle metabolic process	3	2
GO:0071704	organic substance metabolic process	2	2
GO:0090304	nucleic acid metabolic process	4	2
GO:1901360	organic cyclic compound metabolic process	3	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003723	RNA binding	4	11
GO:0003724	RNA helicase activity	3	11
GO:0003743	translation initiation factor activity	4	7
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008135	translation factor activity, RNA binding	3	7
GO:0008186	ATP-dependent activity, acting on RNA	2	11
GO:0016787	hydrolase activity	2	8
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0045182	translation regulator activity	1	7
GO:0090079	translation regulator activity, nucleic acid binding	2	7
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140098	catalytic activity, acting on RNA	3	11
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	97	101	PF00656	0.701
CLV_NRD_NRD_1	30	32	PF00675	0.603
CLV_NRD_NRD_1	638	640	PF00675	0.627
CLV_NRD_NRD_1	88	90	PF00675	0.720
CLV_PCSK_KEX2_1	115	117	PF00082	0.752
CLV_PCSK_KEX2_1	28	30	PF00082	0.600
CLV_PCSK_KEX2_1	637	639	PF00082	0.603
CLV_PCSK_KEX2_1	648	650	PF00082	0.581
CLV_PCSK_KEX2_1	82	84	PF00082	0.687
CLV_PCSK_KEX2_1	86	88	PF00082	0.675
CLV_PCSK_PC1ET2_1	115	117	PF00082	0.784
CLV_PCSK_PC1ET2_1	28	30	PF00082	0.602
CLV_PCSK_PC1ET2_1	637	639	PF00082	0.628
CLV_PCSK_PC1ET2_1	648	650	PF00082	0.571
CLV_PCSK_PC1ET2_1	82	84	PF00082	0.720
CLV_PCSK_PC1ET2_1	86	88	PF00082	0.688
CLV_PCSK_PC7_1	83	89	PF00082	0.789
CLV_PCSK_SKI1_1	184	188	PF00082	0.545
CLV_PCSK_SKI1_1	201	205	PF00082	0.186
CLV_PCSK_SKI1_1	257	261	PF00082	0.243
CLV_PCSK_SKI1_1	311	315	PF00082	0.248
CLV_PCSK_SKI1_1	408	412	PF00082	0.253
CLV_PCSK_SKI1_1	450	454	PF00082	0.259
CLV_PCSK_SKI1_1	583	587	PF00082	0.315
CLV_PCSK_SKI1_1	634	638	PF00082	0.625
DEG_APCC_KENBOX_2	544	548	PF00400	0.355
DEG_SCF_FBW7_1	186	191	PF00400	0.421
DEG_SPOP_SBC_1	103	107	PF00917	0.544
DEG_SPOP_SBC_1	5	9	PF00917	0.531
DOC_ANK_TNKS_1	115	122	PF00023	0.635
DOC_CYCLIN_RxL_1	242	252	PF00134	0.459
DOC_CYCLIN_RxL_1	308	319	PF00134	0.534
DOC_CYCLIN_yClb1_LxF_4	509	515	PF00134	0.362
DOC_MAPK_gen_1	407	418	PF00069	0.448
DOC_MAPK_gen_1	504	514	PF00069	0.510
DOC_MAPK_MEF2A_6	283	292	PF00069	0.459
DOC_MAPK_MEF2A_6	311	318	PF00069	0.448
DOC_MAPK_MEF2A_6	367	374	PF00069	0.379
DOC_MAPK_MEF2A_6	411	418	PF00069	0.445
DOC_MAPK_NFAT4_5	311	319	PF00069	0.448
DOC_PP1_RVXF_1	211	218	PF00149	0.448
DOC_PP1_RVXF_1	360	366	PF00149	0.380
DOC_PP1_RVXF_1	411	418	PF00149	0.448
DOC_PP2B_LxvP_1	475	478	PF13499	0.438
DOC_PP4_FxxP_1	217	220	PF00568	0.448
DOC_PP4_FxxP_1	486	489	PF00568	0.448
DOC_PP4_FxxP_1	514	517	PF00568	0.364
DOC_USP7_MATH_1	103	107	PF00917	0.738
DOC_USP7_MATH_1	127	131	PF00917	0.764
DOC_USP7_MATH_1	139	143	PF00917	0.629
DOC_USP7_MATH_1	188	192	PF00917	0.534
DOC_USP7_MATH_1	22	26	PF00917	0.578
DOC_USP7_MATH_1	6	10	PF00917	0.632
DOC_USP7_MATH_1	617	621	PF00917	0.579
DOC_USP7_MATH_1	73	77	PF00917	0.704
DOC_USP7_UBL2_3	152	156	PF12436	0.622
DOC_USP7_UBL2_3	407	411	PF12436	0.458
DOC_USP7_UBL2_3	644	648	PF12436	0.641
DOC_USP7_UBL2_3	82	86	PF12436	0.782
DOC_WW_Pin1_4	123	128	PF00397	0.692
DOC_WW_Pin1_4	129	134	PF00397	0.599
DOC_WW_Pin1_4	135	140	PF00397	0.765
DOC_WW_Pin1_4	184	189	PF00397	0.525
DOC_WW_Pin1_4	291	296	PF00397	0.438
DOC_WW_Pin1_4	365	370	PF00397	0.499
LIG_14-3-3_CanoR_1	344	348	PF00244	0.441
LIG_14-3-3_CanoR_1	362	366	PF00244	0.433
LIG_14-3-3_CanoR_1	421	427	PF00244	0.440
LIG_14-3-3_CanoR_1	450	455	PF00244	0.448
LIG_14-3-3_CanoR_1	563	570	PF00244	0.316
LIG_Actin_WH2_2	548	565	PF00022	0.316
LIG_BIR_II_1	1	5	PF00653	0.723
LIG_BRCT_BRCA1_1	264	268	PF00533	0.448
LIG_BRCT_BRCA1_1	422	426	PF00533	0.509
LIG_Clathr_ClatBox_1	315	319	PF01394	0.534
LIG_deltaCOP1_diTrp_1	479	486	PF00928	0.454
LIG_FHA_1	234	240	PF00498	0.442
LIG_FHA_1	242	248	PF00498	0.433
LIG_FHA_1	308	314	PF00498	0.452
LIG_FHA_1	352	358	PF00498	0.448
LIG_FHA_1	45	51	PF00498	0.523
LIG_FHA_1	465	471	PF00498	0.444
LIG_FHA_1	5	11	PF00498	0.533
LIG_FHA_2	353	359	PF00498	0.438
LIG_LIR_Apic_2	214	220	PF02991	0.438
LIG_LIR_Gen_1	429	439	PF02991	0.459
LIG_LIR_Gen_1	451	461	PF02991	0.448
LIG_LIR_Gen_1	49	59	PF02991	0.701
LIG_LIR_Nem_3	162	167	PF02991	0.408
LIG_LIR_Nem_3	180	186	PF02991	0.404
LIG_LIR_Nem_3	429	434	PF02991	0.459
LIG_LIR_Nem_3	451	457	PF02991	0.448
LIG_LIR_Nem_3	49	55	PF02991	0.700
LIG_LIR_Nem_3	519	525	PF02991	0.345
LIG_NRBOX	254	260	PF00104	0.448
LIG_PCNA_yPIPBox_3	543	556	PF02747	0.421
LIG_Pex14_1	482	486	PF04695	0.448
LIG_Rb_pABgroove_1	521	529	PF01858	0.418
LIG_REV1ctd_RIR_1	415	425	PF16727	0.448
LIG_SH2_CRK	164	168	PF00017	0.430
LIG_SH2_CRK	403	407	PF00017	0.448
LIG_SH2_PTP2	433	436	PF00017	0.448
LIG_SH2_SRC	433	436	PF00017	0.448
LIG_SH2_SRC	527	530	PF00017	0.413
LIG_SH2_STAP1	52	56	PF00017	0.706
LIG_SH2_STAT5	390	393	PF00017	0.328
LIG_SH2_STAT5	433	436	PF00017	0.448
LIG_SH2_STAT5	495	498	PF00017	0.438
LIG_SH2_STAT5	525	528	PF00017	0.380
LIG_SH2_STAT5	537	540	PF00017	0.422
LIG_SH2_STAT5	561	564	PF00017	0.316
LIG_SH2_STAT5	573	576	PF00017	0.316
LIG_SH3_2	110	115	PF14604	0.658
LIG_SH3_2	489	494	PF14604	0.459
LIG_SH3_3	107	113	PF00018	0.694
LIG_SH3_3	289	295	PF00018	0.509
LIG_SH3_3	486	492	PF00018	0.459
LIG_SUMO_SIM_anti_2	335	341	PF11976	0.448
LIG_SUMO_SIM_par_1	288	294	PF11976	0.473
LIG_SUMO_SIM_par_1	314	320	PF11976	0.448
LIG_TRAF2_1	517	520	PF00917	0.481
LIG_TRAF2_1	67	70	PF00917	0.732
LIG_TYR_ITIM	401	406	PF00017	0.439
LIG_TYR_ITIM	50	55	PF00017	0.548
LIG_UBA3_1	255	260	PF00899	0.448
LIG_UBA3_1	298	303	PF00899	0.448
LIG_UBA3_1	370	378	PF00899	0.415
LIG_UBA3_1	399	407	PF00899	0.442
LIG_UBA3_1	538	545	PF00899	0.349
MOD_CDC14_SPxK_1	294	297	PF00782	0.473
MOD_CDK_SPxK_1	291	297	PF00069	0.438
MOD_CK1_1	125	131	PF00069	0.790
MOD_CK1_1	233	239	PF00069	0.517
MOD_CK1_1	373	379	PF00069	0.578
MOD_CK1_1	420	426	PF00069	0.509
MOD_CK1_1	576	582	PF00069	0.326
MOD_CK1_1	620	626	PF00069	0.574
MOD_CK2_1	172	178	PF00069	0.407
MOD_CK2_1	352	358	PF00069	0.448
MOD_CK2_1	5	11	PF00069	0.672
MOD_CK2_1	620	626	PF00069	0.553
MOD_CK2_1	64	70	PF00069	0.745
MOD_GlcNHglycan	1	4	PF01048	0.768
MOD_GlcNHglycan	106	109	PF01048	0.788
MOD_GlcNHglycan	127	130	PF01048	0.755
MOD_GlcNHglycan	174	177	PF01048	0.483
MOD_GlcNHglycan	227	230	PF01048	0.311
MOD_GlcNHglycan	349	352	PF01048	0.238
MOD_GlcNHglycan	450	453	PF01048	0.254
MOD_GlcNHglycan	461	464	PF01048	0.236
MOD_GlcNHglycan	564	567	PF01048	0.323
MOD_GlcNHglycan	614	617	PF01048	0.523
MOD_GlcNHglycan	626	630	PF01048	0.501
MOD_GlcNHglycan	653	656	PF01048	0.594
MOD_GSK3_1	121	128	PF00069	0.772
MOD_GSK3_1	135	142	PF00069	0.547
MOD_GSK3_1	159	166	PF00069	0.500
MOD_GSK3_1	184	191	PF00069	0.385
MOD_GSK3_1	303	310	PF00069	0.474
MOD_GSK3_1	343	350	PF00069	0.438
MOD_GSK3_1	361	368	PF00069	0.377
MOD_GSK3_1	416	423	PF00069	0.509
MOD_GSK3_1	73	80	PF00069	0.745
MOD_LATS_1	301	307	PF00433	0.474
MOD_LATS_1	448	454	PF00433	0.448
MOD_N-GLC_1	139	144	PF02516	0.667
MOD_N-GLC_1	233	238	PF02516	0.266
MOD_N-GLC_1	262	267	PF02516	0.248
MOD_N-GLC_1	651	656	PF02516	0.602
MOD_NEK2_1	154	159	PF00069	0.612
MOD_NEK2_1	262	267	PF00069	0.450
MOD_NEK2_1	347	352	PF00069	0.438
MOD_NEK2_1	417	422	PF00069	0.438
MOD_NEK2_1	539	544	PF00069	0.443
MOD_NEK2_1	555	560	PF00069	0.341
MOD_NEK2_1	562	567	PF00069	0.292
MOD_NEK2_1	575	580	PF00069	0.117
MOD_NEK2_1	610	615	PF00069	0.509
MOD_NEK2_2	361	366	PF00069	0.384
MOD_PIKK_1	145	151	PF00454	0.666
MOD_PIKK_1	349	355	PF00454	0.448
MOD_PIKK_1	610	616	PF00454	0.509
MOD_PKA_2	230	236	PF00069	0.513
MOD_PKA_2	343	349	PF00069	0.438
MOD_PKA_2	361	367	PF00069	0.375
MOD_PKA_2	420	426	PF00069	0.501
MOD_PKA_2	562	568	PF00069	0.316
MOD_PKA_2	630	636	PF00069	0.698
MOD_Plk_1	625	631	PF00069	0.665
MOD_Plk_2-3	379	385	PF00069	0.430
MOD_Plk_2-3	64	70	PF00069	0.700
MOD_Plk_2-3	90	96	PF00069	0.767
MOD_Plk_4	264	270	PF00069	0.491
MOD_Plk_4	343	349	PF00069	0.464
MOD_Plk_4	450	456	PF00069	0.448
MOD_ProDKin_1	123	129	PF00069	0.690
MOD_ProDKin_1	135	141	PF00069	0.763
MOD_ProDKin_1	184	190	PF00069	0.421
MOD_ProDKin_1	291	297	PF00069	0.438
MOD_ProDKin_1	365	371	PF00069	0.499
MOD_SUMO_rev_2	157	167	PF00179	0.463
MOD_SUMO_rev_2	175	183	PF00179	0.357
MOD_SUMO_rev_2	202	209	PF00179	0.448
MOD_SUMO_rev_2	528	532	PF00179	0.488
TRG_DiLeu_BaEn_1	335	340	PF01217	0.448
TRG_DiLeu_BaEn_1	396	401	PF01217	0.352
TRG_DiLeu_BaLyEn_6	294	299	PF01217	0.448
TRG_DiLeu_BaLyEn_6	395	400	PF01217	0.338
TRG_ENDOCYTIC_2	164	167	PF00928	0.410
TRG_ENDOCYTIC_2	403	406	PF00928	0.445
TRG_ENDOCYTIC_2	433	436	PF00928	0.448
TRG_ENDOCYTIC_2	454	457	PF00928	0.448
TRG_ENDOCYTIC_2	52	55	PF00928	0.708
TRG_ER_diArg_1	29	31	PF00400	0.653
TRG_ER_diArg_1	87	89	PF00400	0.690
TRG_NES_CRM1_1	592	604	PF08389	0.311
TRG_NLS_MonoCore_2	26	31	PF00514	0.609
TRG_NLS_MonoExtC_3	26	31	PF00514	0.632
TRG_NLS_MonoExtC_3	620	626	PF00514	0.534
TRG_NLS_MonoExtN_4	27	32	PF00514	0.617
TRG_NLS_MonoExtN_4	408	415	PF00514	0.448
TRG_Pf-PMV_PEXEL_1	201	206	PF00026	0.259
TRG_Pf-PMV_PEXEL_1	245	250	PF00026	0.238

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7J1	Leptomonas seymouri	37%	73%
A0A0N0P942	Leptomonas seymouri	27%	76%
A0A0N1I6K5	Leptomonas seymouri	78%	100%
A0A0N1IKV7	Leptomonas seymouri	32%	95%
A0A0N1PCZ7	Leptomonas seymouri	24%	100%
A0A0S4IWD0	Bodo saltans	72%	100%
A0A0S4KKU4	Bodo saltans	37%	95%
A0A1D6LAB7	Zea mays	32%	88%
A0A1X0NJH3	Trypanosomatidae	26%	100%
A0A1X0NMD6	Trypanosomatidae	28%	80%
A0A1X0P5E1	Trypanosomatidae	33%	92%
A0A1X0P7S4	Trypanosomatidae	84%	100%
A0A3Q8IC45	Leishmania donovani	29%	100%
A0A3Q8ID91	Leishmania donovani	33%	100%
A0A3R7LQQ6	Trypanosoma rangeli	28%	69%
A0A3R7M1K3	Trypanosoma rangeli	35%	92%
A0A3R7NGQ1	Trypanosoma rangeli	68%	100%
A0A3S5H5G1	Leishmania donovani	31%	97%
A0A3S5H7C7	Leishmania donovani	23%	100%
A0A3S7WQ33	Leishmania donovani	27%	100%
A0A3S7X579	Leishmania donovani	29%	100%
A0A3S7X5R1	Leishmania donovani	31%	85%
A0A3S7XAN8	Leishmania donovani	95%	100%
A0A3S7XAT8	Leishmania donovani	33%	100%
A0A422NYB4	Trypanosoma rangeli	37%	78%
A1CB55	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	29%	87%
A1CIQ5	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	43%	100%
A1CKJ0	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	31%	100%
A1CL59	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	32%	100%
A1CTZ2	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	41%	80%
A1CW14	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	43%	100%
A1D699	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	32%	100%
A1DE84	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	29%	87%
A1DNF9	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	38%	81%
A2Q9T6	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	53%	100%
A2QE29	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	31%	100%
A2RA55	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	29%	85%
A3GGE9	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	36%	86%
A3LNR6	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	52%	100%
A3LWH3	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	28%	90%
A3LX02	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	30%	100%
A4HGH8	Leishmania braziliensis	38%	73%
A4HGR1	Leishmania braziliensis	31%	100%
A4HK38	Leishmania braziliensis	30%	100%
A4HKL3	Leishmania braziliensis	36%	85%
A4HP48	Leishmania braziliensis	87%	100%
A4HP49	Leishmania braziliensis	32%	100%
A4HSE3	Leishmania infantum	31%	97%
A4HT33	Leishmania infantum	35%	100%
A4HTF8	Leishmania infantum	27%	100%
A4HZF8	Leishmania infantum	27%	100%
A4I3T6	Leishmania infantum	33%	100%
A4I7M5	Leishmania infantum	29%	100%
A4I846	Leishmania infantum	32%	85%
A4IDF5	Leishmania infantum	95%	100%
A4IDF6	Leishmania infantum	33%	100%
A4R8B5	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	52%	100%
A4RGU2	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	38%	82%
A4RK80	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	30%	97%
A5DAR2	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	30%	88%
A5DGM4	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	32%	100%
A5DID7	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	49%	100%
A5DLF4	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	36%	87%
A5E2I8	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	30%	100%
A5E2Z9	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	53%	100%
A5E3K3	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	37%	85%
A6R918	Ajellomyces capsulatus (strain NAm1 / WU24)	31%	97%
A6RMZ2	Botryotinia fuckeliana (strain B05.10)	31%	100%
A6RSH5	Botryotinia fuckeliana (strain B05.10)	31%	75%
A6ZPU3	Saccharomyces cerevisiae (strain YJM789)	39%	85%
A6ZZY8	Saccharomyces cerevisiae (strain YJM789)	29%	89%
A7A237	Saccharomyces cerevisiae (strain YJM789)	32%	100%
A7ESL8	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	38%	81%
A7F2S3	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	30%	100%
A7F8V8	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	31%	75%
A7TJ71	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	39%	86%
A7TJS7	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	30%	100%
C9ZPV9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	79%
D0A331	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	76%	100%
D0A6Z3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
E9AH36	Leishmania infantum	23%	100%
E9AJG4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9AKB8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	96%
E9ASV6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
E9ASV7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9AVE1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9AWL4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9B028	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9B2I0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9B304	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	85%
O60173	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	31%	93%
O74764	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	100%
P0CQ82	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	38%	76%
P0CQ83	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	38%	76%
P0CQ84	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	49%	100%
P0CQ85	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	49%	100%
P0CR02	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	30%	100%
P0CR03	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	30%	100%
P20448	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	39%	85%
P25808	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	32%	100%
P34640	Caenorhabditis elegans	32%	100%
P36120	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	29%	89%
P57453	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	33%	100%
P96614	Bacillus subtilis (strain 168)	31%	100%
Q03532	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	52%	100%
Q09916	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	51%	100%
Q0CF43	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	31%	85%
Q0CMM5	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	41%	82%
Q0CQF3	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	32%	100%
Q0CZS8	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	47%	100%
Q0D622	Oryza sativa subsp. japonica	39%	85%
Q0D8N0	Oryza sativa subsp. japonica	31%	100%
Q0DBS1	Oryza sativa subsp. japonica	47%	100%
Q0DBU5	Oryza sativa subsp. japonica	34%	100%
Q0DLB9	Oryza sativa subsp. japonica	32%	100%
Q0U8V9	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	33%	100%
Q0UMB9	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	40%	82%
Q0UP45	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	32%	100%
Q0UR48	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	49%	100%
Q13206	Homo sapiens	40%	75%
Q1E1R7	Coccidioides immitis (strain RS)	32%	100%
Q1E2B2	Coccidioides immitis (strain RS)	31%	78%
Q1E9T9	Coccidioides immitis (strain RS)	31%	85%
Q1EA54	Coccidioides immitis (strain RS)	51%	100%
Q1EB31	Coccidioides immitis (strain RS)	38%	82%
Q2GMX1	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	52%	100%
Q2GV49	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	34%	100%
Q2GZU7	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	31%	82%
Q2H2J1	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	40%	80%
Q2NL08	Bos taurus	39%	100%
Q2UBZ5	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	32%	100%
Q2UE66	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	30%	86%
Q2UST1	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	31%	100%
Q2UUN6	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	52%	100%
Q4HVW2	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	31%	100%
Q4HZ68	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	30%	88%
Q4IAS1	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	37%	83%
Q4IEK8	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	52%	100%
Q4PEX7	Ustilago maydis (strain 521 / FGSC 9021)	29%	100%
Q4Q1N9	Leishmania major	33%	100%
Q4Q552	Leishmania major	34%	85%
Q4Q5M6	Leishmania major	30%	100%
Q4Q858	Leishmania major	31%	100%
Q4QC38	Leishmania major	29%	100%
Q4QJI9	Leishmania major	31%	97%
Q4WM60	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	38%	83%
Q4WQM4	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	50%	100%
Q4WV71	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	30%	87%
Q4WYJ7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	32%	100%
Q54EC2	Dictyostelium discoideum	34%	99%
Q54Q94	Dictyostelium discoideum	38%	75%
Q54S03	Dictyostelium discoideum	51%	100%
Q59N29	Candida albicans (strain SC5314 / ATCC MYA-2876)	30%	100%
Q59S50	Candida albicans (strain SC5314 / ATCC MYA-2876)	28%	90%
Q5AF95	Candida albicans (strain SC5314 / ATCC MYA-2876)	37%	86%
Q5AK59	Candida albicans (strain SC5314 / ATCC MYA-2876)	53%	100%
Q5APM7	Candida albicans (strain SC5314 / ATCC MYA-2876)	33%	98%
Q5B3H7	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	33%	100%
Q5B8F4	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	32%	100%
Q5BBY1	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	53%	100%
Q5BFU1	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	39%	81%
Q5BGX6	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	29%	84%
Q5VQL1	Oryza sativa subsp. japonica	30%	93%
Q5ZJF6	Gallus gallus	38%	75%
Q5ZLN8	Gallus gallus	39%	100%
Q61R02	Caenorhabditis briggsae	32%	100%
Q65N62	Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46)	31%	100%
Q6AZV7	Xenopus laevis	38%	100%
Q6BH93	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	51%	100%
Q6BKH3	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	29%	82%
Q6BSM3	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	31%	100%
Q6BXG0	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	38%	86%
Q6C193	Yarrowia lipolytica (strain CLIB 122 / E 150)	32%	100%
Q6C7D2	Yarrowia lipolytica (strain CLIB 122 / E 150)	52%	100%
Q6C835	Yarrowia lipolytica (strain CLIB 122 / E 150)	31%	82%
Q6CGD1	Yarrowia lipolytica (strain CLIB 122 / E 150)	38%	89%
Q6CK32	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	28%	89%
Q6CN92	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	32%	100%
Q6CRF4	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	38%	85%
Q6CXB7	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	52%	100%
Q6FIL3	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	53%	100%
Q6FKS8	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	31%	100%
Q6FPT7	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	37%	86%
Q6K7R9	Oryza sativa subsp. japonica	30%	81%
Q6NZQ2	Mus musculus	33%	96%
Q6ZPL9	Mus musculus	39%	100%
Q74Z73	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	51%	100%
Q750F8	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	32%	100%
Q754J2	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	28%	93%
Q75C76	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	36%	86%
Q7RYZ7	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	34%	100%
Q7RZ35	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	39%	80%
Q7S2N9	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	51%	100%
Q7S873	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	31%	81%
Q7XJN0	Arabidopsis thaliana	32%	100%
Q80Y44	Mus musculus	40%	75%
Q84T03	Oryza sativa subsp. japonica	48%	100%
Q86B47	Drosophila melanogaster	32%	67%
Q873H9	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	30%	100%
Q8GXD6	Arabidopsis thaliana	34%	100%
Q8JHJ2	Danio rerio	38%	100%
Q8K363	Mus musculus	54%	100%
Q8NHQ9	Homo sapiens	39%	100%
Q8SR49	Encephalitozoon cuniculi (strain GB-M1)	32%	100%
Q94C75	Arabidopsis thaliana	32%	100%
Q9FFQ1	Arabidopsis thaliana	32%	92%
Q9FLB0	Arabidopsis thaliana	32%	100%
Q9FNM7	Arabidopsis thaliana	33%	77%
Q9H8H2	Homo sapiens	33%	77%
Q9LIH9	Arabidopsis thaliana	46%	100%
Q9NVP1	Homo sapiens	53%	98%
Q9SB89	Arabidopsis thaliana	46%	100%
Q9VD51	Drosophila melanogaster	54%	97%
Q9VHU1	Drosophila melanogaster	34%	100%
Q9Y7C4	Candida albicans (strain SC5314 / ATCC MYA-2876)	29%	100%
V5DAZ9	Trypanosoma cruzi	37%	69%
V5DCA1	Trypanosoma cruzi	36%	92%
V5DDC5	Trypanosoma cruzi	28%	69%
V5DKV2	Trypanosoma cruzi	70%	100%