Type I site-specific deoxyribonuclease

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q1M4_LEIMA

TriTrypDb:

LmjF.36.1990 , LMJLV39_360026800 , LMJSD75_360026900

Length:

166

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4Q1M4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q1M4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	164	166	PF00675	0.562
CLV_NRD_NRD_1	77	79	PF00675	0.521
CLV_PCSK_KEX2_1	164	166	PF00082	0.562
CLV_PCSK_KEX2_1	77	79	PF00082	0.521
CLV_PCSK_SKI1_1	41	45	PF00082	0.626
DEG_Nend_UBRbox_1	1	4	PF02207	0.603
DOC_CYCLIN_RxL_1	56	67	PF00134	0.804
DOC_MAPK_gen_1	146	158	PF00069	0.727
DOC_MAPK_JIP1_4	41	47	PF00069	0.828
DOC_MAPK_MEF2A_6	151	160	PF00069	0.721
DOC_PP1_RVXF_1	57	64	PF00149	0.806
DOC_PP2B_LxvP_1	25	28	PF13499	0.757
DOC_PP4_MxPP_1	87	90	PF00568	0.732
DOC_USP7_MATH_1	28	32	PF00917	0.808
LIG_14-3-3_CanoR_1	118	123	PF00244	0.688
LIG_14-3-3_CanoR_1	35	45	PF00244	0.825
LIG_APCC_ABBA_1	156	161	PF00400	0.719
LIG_BRCT_BRCA1_1	13	17	PF00533	0.427
LIG_BRCT_BRCA1_1	6	10	PF00533	0.549
LIG_Clathr_ClatBox_1	157	161	PF01394	0.724
LIG_FAT_LD_1	153	161	PF03623	0.720
LIG_FHA_2	119	125	PF00498	0.696
LIG_LIR_Gen_1	7	17	PF02991	0.549
LIG_LIR_Nem_3	116	122	PF02991	0.695
LIG_LIR_Nem_3	7	13	PF02991	0.549
LIG_Pex14_2	8	12	PF04695	0.549
LIG_SH2_CRK	3	7	PF00017	0.449
LIG_SH2_STAT3	117	120	PF00017	0.701
LIG_SH2_STAT5	122	125	PF00017	0.702
LIG_SH2_STAT5	127	130	PF00017	0.667
LIG_SH2_STAT5	159	162	PF00017	0.718
LIG_SH2_STAT5	3	6	PF00017	0.449
LIG_SH2_STAT5	94	97	PF00017	0.705
LIG_SH3_1	146	152	PF00018	0.732
LIG_SH3_3	146	152	PF00018	0.732
LIG_TRAF2_1	152	155	PF00917	0.720
MOD_CK2_1	64	70	PF00069	0.776
MOD_GlcNHglycan	70	73	PF01048	0.517
MOD_GSK3_1	11	18	PF00069	0.549
MOD_GSK3_1	64	71	PF00069	0.770
MOD_NEK2_1	1	6	PF00069	0.596
MOD_NEK2_1	15	20	PF00069	0.305
MOD_NEK2_1	36	41	PF00069	0.827
MOD_NEK2_1	99	104	PF00069	0.703
MOD_NEK2_2	21	26	PF00069	0.549
MOD_PIKK_1	127	133	PF00454	0.727
MOD_PIKK_1	28	34	PF00454	0.809
MOD_PIKK_1	36	42	PF00454	0.724
MOD_PKA_2	1	7	PF00069	0.449
MOD_PKA_2	34	40	PF00069	0.823
MOD_Plk_4	118	124	PF00069	0.693
TRG_DiLeu_BaEn_1	110	115	PF01217	0.709
TRG_DiLeu_LyEn_5	110	115	PF01217	0.709
TRG_ENDOCYTIC_2	3	6	PF00928	0.449
TRG_ER_diArg_1	77	79	PF00400	0.721
TRG_Pf-PMV_PEXEL_1	151	155	PF00026	0.522