Putative caltractin

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Putative caltractin

Gene product:

caltractin, putative

Species:

Leishmania major

UniProt:

Q4Q1H8_LEIMA

TriTrypDb:

LmjF.36.2430 , LMJLV39_360032200 , LMJSD75_360032200

Length:

239

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4Q1H8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q1H8

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	3
GO:0005509	calcium ion binding	5	3
GO:0043167	ion binding	2	3
GO:0043169	cation binding	3	3
GO:0046872	metal ion binding	4	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	141	145	PF00656	0.480
CLV_C14_Caspase3-7	61	65	PF00656	0.724
CLV_C14_Caspase3-7	67	71	PF00656	0.753
CLV_NRD_NRD_1	156	158	PF00675	0.488
CLV_NRD_NRD_1	190	192	PF00675	0.523
CLV_NRD_NRD_1	233	235	PF00675	0.552
CLV_NRD_NRD_1	50	52	PF00675	0.558
CLV_PCSK_KEX2_1	190	192	PF00082	0.523
CLV_PCSK_KEX2_1	50	52	PF00082	0.558
CLV_PCSK_SKI1_1	157	161	PF00082	0.643
CLV_PCSK_SKI1_1	51	55	PF00082	0.521
DEG_APCC_DBOX_1	17	25	PF00400	0.532
DEG_Nend_UBRbox_3	1	3	PF02207	0.564
DOC_MAPK_gen_1	15	24	PF00069	0.547
DOC_PP1_RVXF_1	21	28	PF00149	0.575
DOC_PP4_FxxP_1	132	135	PF00568	0.741
DOC_SPAK_OSR1_1	75	79	PF12202	0.641
DOC_USP7_MATH_1	123	127	PF00917	0.508
DOC_USP7_MATH_1	86	90	PF00917	0.605
DOC_WW_Pin1_4	114	119	PF00397	0.493
DOC_WW_Pin1_4	131	136	PF00397	0.523
DOC_WW_Pin1_4	59	64	PF00397	0.786
DOC_WW_Pin1_4	81	86	PF00397	0.648
DOC_WW_Pin1_4	95	100	PF00397	0.761
LIG_14-3-3_CanoR_1	15	25	PF00244	0.515
LIG_14-3-3_CanoR_1	50	54	PF00244	0.559
LIG_14-3-3_CanoR_1	6	12	PF00244	0.610
LIG_14-3-3_CanoR_1	75	85	PF00244	0.596
LIG_FHA_1	122	128	PF00498	0.617
LIG_FHA_1	169	175	PF00498	0.454
LIG_FHA_1	216	222	PF00498	0.460
LIG_FHA_1	72	78	PF00498	0.564
LIG_FHA_1	90	96	PF00498	0.622
LIG_FHA_2	199	205	PF00498	0.492
LIG_FHA_2	223	229	PF00498	0.458
LIG_FHA_2	65	71	PF00498	0.754
LIG_LIR_Gen_1	149	159	PF02991	0.497
LIG_LIR_Gen_1	169	180	PF02991	0.259
LIG_LIR_Gen_1	224	233	PF02991	0.577
LIG_LIR_Nem_3	169	175	PF02991	0.399
LIG_LIR_Nem_3	177	183	PF02991	0.411
LIG_LIR_Nem_3	207	212	PF02991	0.483
LIG_LIR_Nem_3	224	229	PF02991	0.451
LIG_Rb_pABgroove_1	203	211	PF01858	0.478
LIG_SH2_STAP1	164	168	PF00017	0.466
LIG_SH2_STAP1	170	174	PF00017	0.467
LIG_SH2_STAT5	170	173	PF00017	0.538
LIG_SH2_STAT5	9	12	PF00017	0.530
LIG_SH3_3	115	121	PF00018	0.664
LIG_TRAF2_1	163	166	PF00917	0.518
LIG_WRC_WIRS_1	223	228	PF05994	0.452
LIG_WRC_WIRS_1	90	95	PF05994	0.544
MOD_CK1_1	134	140	PF00069	0.658
MOD_CK1_1	224	230	PF00069	0.507
MOD_CK1_1	52	58	PF00069	0.740
MOD_CK1_1	59	65	PF00069	0.764
MOD_CK1_1	79	85	PF00069	0.682
MOD_CK1_1	89	95	PF00069	0.724
MOD_CK1_1	98	104	PF00069	0.752
MOD_CK2_1	160	166	PF00069	0.532
MOD_CK2_1	198	204	PF00069	0.507
MOD_CK2_1	91	97	PF00069	0.712
MOD_DYRK1A_RPxSP_1	81	85	PF00069	0.524
MOD_GlcNHglycan	112	115	PF01048	0.728
MOD_GlcNHglycan	121	124	PF01048	0.735
MOD_GlcNHglycan	55	58	PF01048	0.727
MOD_GSK3_1	110	117	PF00069	0.621
MOD_GSK3_1	119	126	PF00069	0.466
MOD_GSK3_1	211	218	PF00069	0.477
MOD_GSK3_1	45	52	PF00069	0.658
MOD_GSK3_1	59	66	PF00069	0.679
MOD_GSK3_1	76	83	PF00069	0.677
MOD_GSK3_1	91	98	PF00069	0.716
MOD_GSK3_1	99	106	PF00069	0.678
MOD_NEK2_1	110	115	PF00069	0.717
MOD_NEK2_1	168	173	PF00069	0.459
MOD_NEK2_1	76	81	PF00069	0.642
MOD_PIKK_1	125	131	PF00454	0.759
MOD_PIKK_1	45	51	PF00454	0.694
MOD_PIKK_1	99	105	PF00454	0.702
MOD_PKA_2	49	55	PF00069	0.559
MOD_PKA_2	80	86	PF00069	0.628
MOD_Plk_1	166	172	PF00069	0.538
MOD_Plk_1	176	182	PF00069	0.528
MOD_Plk_1	221	227	PF00069	0.442
MOD_Plk_1	71	77	PF00069	0.649
MOD_Plk_2-3	198	204	PF00069	0.507
MOD_Plk_2-3	222	228	PF00069	0.506
MOD_ProDKin_1	114	120	PF00069	0.487
MOD_ProDKin_1	131	137	PF00069	0.522
MOD_ProDKin_1	59	65	PF00069	0.782
MOD_ProDKin_1	81	87	PF00069	0.646
MOD_ProDKin_1	95	101	PF00069	0.761
TRG_DiLeu_BaEn_1	20	25	PF01217	0.540
TRG_ENDOCYTIC_2	180	183	PF00928	0.467
TRG_ER_diArg_1	189	191	PF00400	0.519

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5G8	Leptomonas seymouri	49%	100%
A0A3S7XAY6	Leishmania donovani	87%	100%
A0A422NCF5	Trypanosoma rangeli	35%	100%
A4HPA9	Leishmania braziliensis	70%	100%
A4ICE9	Leishmania infantum	87%	100%
E9AT20	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	90%