Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

small nuclear RNA-activating protein

Species:

Leishmania major

UniProt:

Q4Q1G9_LEIMA

TriTrypDb:

LmjF.36.2520 , LMJLV39_360033200 , LMJSD75_360033200

Length:

350

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q1G9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q1G9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	256	258	PF00675	0.521
CLV_NRD_NRD_1	342	344	PF00675	0.592
CLV_PCSK_KEX2_1	256	258	PF00082	0.654
CLV_PCSK_KEX2_1	341	343	PF00082	0.584
CLV_PCSK_SKI1_1	202	206	PF00082	0.474
CLV_PCSK_SKI1_1	250	254	PF00082	0.429
CLV_PCSK_SKI1_1	256	260	PF00082	0.451
CLV_PCSK_SKI1_1	296	300	PF00082	0.585
CLV_PCSK_SKI1_1	306	310	PF00082	0.498
CLV_PCSK_SKI1_1	342	346	PF00082	0.589
CLV_PCSK_SKI1_1	61	65	PF00082	0.531
DEG_APCC_DBOX_1	201	209	PF00400	0.441
DEG_SIAH_1	220	228	PF03145	0.524
DOC_CYCLIN_RxL_1	199	209	PF00134	0.440
DOC_CYCLIN_RxL_1	290	302	PF00134	0.542
DOC_CYCLIN_RxL_1	339	348	PF00134	0.581
DOC_CYCLIN_yCln2_LP_2	187	193	PF00134	0.577
DOC_CYCLIN_yCln2_LP_2	59	65	PF00134	0.483
DOC_MAPK_DCC_7	188	198	PF00069	0.528
DOC_MAPK_gen_1	88	97	PF00069	0.349
DOC_MAPK_MEF2A_6	91	99	PF00069	0.342
DOC_PP2B_LxvP_1	187	190	PF13499	0.616
DOC_PP2B_LxvP_1	79	82	PF13499	0.386
DOC_PP4_FxxP_1	28	31	PF00568	0.458
DOC_PP4_FxxP_1	325	328	PF00568	0.545
DOC_USP7_MATH_1	126	130	PF00917	0.604
DOC_USP7_MATH_1	144	148	PF00917	0.495
DOC_WW_Pin1_4	177	182	PF00397	0.665
DOC_WW_Pin1_4	237	242	PF00397	0.590
DOC_WW_Pin1_4	289	294	PF00397	0.576
LIG_14-3-3_CanoR_1	172	178	PF00244	0.605
LIG_14-3-3_CanoR_1	88	94	PF00244	0.353
LIG_14-3-3_CanoR_1	9	17	PF00244	0.469
LIG_CtBP_PxDLS_1	184	188	PF00389	0.523
LIG_FHA_1	66	72	PF00498	0.431
LIG_FHA_1	90	96	PF00498	0.373
LIG_FHA_2	3	9	PF00498	0.556
LIG_FHA_2	33	39	PF00498	0.390
LIG_FHA_2	55	61	PF00498	0.499
LIG_LIR_Apic_2	322	328	PF02991	0.544
LIG_LIR_Gen_1	16	25	PF02991	0.357
LIG_LIR_Gen_1	327	337	PF02991	0.515
LIG_LIR_Gen_1	37	45	PF02991	0.550
LIG_LIR_Gen_1	75	86	PF02991	0.430
LIG_LIR_Nem_3	16	20	PF02991	0.355
LIG_LIR_Nem_3	327	333	PF02991	0.585
LIG_LIR_Nem_3	37	42	PF02991	0.549
LIG_LIR_Nem_3	49	53	PF02991	0.462
LIG_LIR_Nem_3	60	66	PF02991	0.508
LIG_LIR_Nem_3	75	81	PF02991	0.392
LIG_LIR_Nem_3	92	96	PF02991	0.327
LIG_LIR_Nem_3	98	102	PF02991	0.353
LIG_NRP_CendR_1	349	350	PF00754	0.618
LIG_Pex14_2	24	28	PF04695	0.399
LIG_Pex14_2	39	43	PF04695	0.339
LIG_SH2_CRK	17	21	PF00017	0.434
LIG_SH2_STAP1	17	21	PF00017	0.411
LIG_SH2_STAT3	102	105	PF00017	0.405
LIG_SH2_STAT3	266	269	PF00017	0.697
LIG_SH2_STAT5	266	269	PF00017	0.531
LIG_SH2_STAT5	50	53	PF00017	0.461
LIG_SH2_STAT5	78	81	PF00017	0.369
LIG_SH3_1	108	114	PF00018	0.581
LIG_SH3_3	108	114	PF00018	0.581
LIG_SH3_3	175	181	PF00018	0.652
LIG_SH3_3	187	193	PF00018	0.500
LIG_SH3_3	315	321	PF00018	0.523
LIG_SH3_3	59	65	PF00018	0.483
LIG_SUMO_SIM_par_1	194	199	PF11976	0.431
LIG_SUMO_SIM_par_1	68	76	PF11976	0.424
LIG_TRAF2_1	168	171	PF00917	0.577
LIG_TRAF2_1	314	317	PF00917	0.656
LIG_WRC_WIRS_1	90	95	PF05994	0.307
LIG_WRC_WIRS_1	96	101	PF05994	0.405
MOD_CDK_SPxxK_3	289	296	PF00069	0.578
MOD_CK1_1	116	122	PF00069	0.591
MOD_CK1_1	129	135	PF00069	0.594
MOD_CK1_1	155	161	PF00069	0.624
MOD_CK1_1	206	212	PF00069	0.465
MOD_CK2_1	129	135	PF00069	0.635
MOD_CK2_1	165	171	PF00069	0.657
MOD_CK2_1	2	8	PF00069	0.507
MOD_CK2_1	242	248	PF00069	0.442
MOD_CK2_1	43	49	PF00069	0.427
MOD_CK2_1	54	60	PF00069	0.588
MOD_CK2_1	77	83	PF00069	0.382
MOD_GlcNHglycan	135	138	PF01048	0.742
MOD_GlcNHglycan	140	143	PF01048	0.775
MOD_GlcNHglycan	167	170	PF01048	0.786
MOD_GlcNHglycan	213	216	PF01048	0.573
MOD_GlcNHglycan	217	220	PF01048	0.605
MOD_GlcNHglycan	221	224	PF01048	0.611
MOD_GlcNHglycan	237	240	PF01048	0.711
MOD_GlcNHglycan	273	276	PF01048	0.435
MOD_GlcNHglycan	277	280	PF01048	0.402
MOD_GlcNHglycan	311	314	PF01048	0.591
MOD_GlcNHglycan	75	78	PF01048	0.350
MOD_GSK3_1	116	123	PF00069	0.626
MOD_GSK3_1	129	136	PF00069	0.564
MOD_GSK3_1	152	159	PF00069	0.622
MOD_GSK3_1	173	180	PF00069	0.779
MOD_GSK3_1	211	218	PF00069	0.597
MOD_GSK3_1	271	278	PF00069	0.465
MOD_GSK3_1	73	80	PF00069	0.419
MOD_N-GLC_1	309	314	PF02516	0.598
MOD_NEK2_1	133	138	PF00069	0.619
MOD_NEK2_1	152	157	PF00069	0.548
MOD_NEK2_1	203	208	PF00069	0.451
MOD_NEK2_1	299	304	PF00069	0.489
MOD_NEK2_1	309	314	PF00069	0.558
MOD_NEK2_1	43	48	PF00069	0.407
MOD_NEK2_1	72	77	PF00069	0.347
MOD_NEK2_1	95	100	PF00069	0.350
MOD_PIKK_1	101	107	PF00454	0.422
MOD_PIKK_1	158	164	PF00454	0.746
MOD_PKA_1	256	262	PF00069	0.511
MOD_PKA_2	144	150	PF00069	0.602
MOD_PKA_2	2	8	PF00069	0.507
MOD_PKA_2	206	212	PF00069	0.451
MOD_PKA_2	256	262	PF00069	0.574
MOD_PKA_2	32	38	PF00069	0.465
MOD_Plk_1	43	49	PF00069	0.481
MOD_Plk_2-3	32	38	PF00069	0.400
MOD_Plk_4	129	135	PF00069	0.612
MOD_Plk_4	320	326	PF00069	0.566
MOD_Plk_4	95	101	PF00069	0.352
MOD_ProDKin_1	177	183	PF00069	0.665
MOD_ProDKin_1	237	243	PF00069	0.581
MOD_ProDKin_1	289	295	PF00069	0.574
MOD_SUMO_rev_2	116	124	PF00179	0.530
MOD_SUMO_rev_2	245	252	PF00179	0.488
TRG_DiLeu_BaLyEn_6	199	204	PF01217	0.494
TRG_DiLeu_BaLyEn_6	340	345	PF01217	0.586
TRG_ENDOCYTIC_2	17	20	PF00928	0.367
TRG_ENDOCYTIC_2	21	24	PF00928	0.337
TRG_ENDOCYTIC_2	78	81	PF00928	0.513
TRG_ER_diArg_1	108	111	PF00400	0.642
TRG_ER_diArg_1	255	257	PF00400	0.507
TRG_ER_diArg_1	331	334	PF00400	0.512
TRG_ER_diArg_1	341	343	PF00400	0.668
TRG_NES_CRM1_1	19	32	PF08389	0.445
TRG_Pf-PMV_PEXEL_1	343	348	PF00026	0.586

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5Y4	Leptomonas seymouri	47%	100%
A0A3S7XB07	Leishmania donovani	92%	100%
A4HPB8	Leishmania braziliensis	80%	100%
A4ICF8	Leishmania infantum	93%	100%
E9AT29	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%