LeishMANIAdb
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Fanconi-associated nuclease

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Fanconi-associated nuclease
Gene product:
VRR-NUC domain containing protein, putative
Species:
Leishmania major
UniProt:
Q4Q1F9_LEIMA
TriTrypDb:
LmjF.36.2620 , LMJLV39_360034600 * , LMJSD75_360034600 *
Length:
1725

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Cellular components
Term Name Level Count
GO:0005634 nucleus 5 6
GO:0005737 cytoplasm 2 2
GO:0031974 membrane-enclosed lumen 2 2
GO:0031981 nuclear lumen 5 2
GO:0043226 organelle 2 6
GO:0043227 membrane-bounded organelle 3 6
GO:0043229 intracellular organelle 3 6
GO:0043231 intracellular membrane-bounded organelle 4 6
GO:0043233 organelle lumen 3 2
GO:0070013 intracellular organelle lumen 4 2
GO:0110165 cellular anatomical entity 1 6

Expansion

Sequence features

Q4Q1F9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 6
GO:0006259 DNA metabolic process 4 6
GO:0006281 DNA repair 5 6
GO:0006725 cellular aromatic compound metabolic process 3 6
GO:0006807 nitrogen compound metabolic process 2 6
GO:0006950 response to stress 2 6
GO:0006974 DNA damage response 4 6
GO:0008152 metabolic process 1 6
GO:0009987 cellular process 1 6
GO:0033554 cellular response to stress 3 6
GO:0034641 cellular nitrogen compound metabolic process 3 6
GO:0036297 interstrand cross-link repair 6 6
GO:0043170 macromolecule metabolic process 3 6
GO:0044237 cellular metabolic process 2 6
GO:0044238 primary metabolic process 2 6
GO:0044260 obsolete cellular macromolecule metabolic process 3 6
GO:0046483 heterocycle metabolic process 3 6
GO:0050896 response to stimulus 1 6
GO:0051716 cellular response to stimulus 2 6
GO:0071704 organic substance metabolic process 2 6
GO:0090304 nucleic acid metabolic process 4 6
GO:1901360 organic cyclic compound metabolic process 3 6
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 2
GO:0003677 DNA binding 4 2
GO:0003824 catalytic activity 1 6
GO:0004518 nuclease activity 4 6
GO:0004519 endonuclease activity 5 2
GO:0004520 DNA endonuclease activity 5 2
GO:0004527 exonuclease activity 5 6
GO:0004528 phosphodiesterase I activity 6 6
GO:0004536 DNA nuclease activity 4 2
GO:0005488 binding 1 6
GO:0008081 phosphoric diester hydrolase activity 5 6
GO:0008409 5'-3' exonuclease activity 6 2
GO:0016787 hydrolase activity 2 6
GO:0016788 hydrolase activity, acting on ester bonds 3 6
GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 6 2
GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 6 2
GO:0017108 5'-flap endonuclease activity 7 2
GO:0042578 phosphoric ester hydrolase activity 4 6
GO:0043167 ion binding 2 6
GO:0043169 cation binding 3 6
GO:0046872 metal ion binding 4 6
GO:0048256 flap endonuclease activity 6 2
GO:0070336 flap-structured DNA binding 5 2
GO:0097159 organic cyclic compound binding 2 2
GO:0140097 catalytic activity, acting on DNA 3 2
GO:0140640 catalytic activity, acting on a nucleic acid 2 2
GO:1901363 heterocyclic compound binding 2 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1298 1302 PF00656 0.524
CLV_C14_Caspase3-7 1327 1331 PF00656 0.640
CLV_C14_Caspase3-7 1572 1576 PF00656 0.592
CLV_C14_Caspase3-7 188 192 PF00656 0.521
CLV_C14_Caspase3-7 25 29 PF00656 0.646
CLV_C14_Caspase3-7 260 264 PF00656 0.458
CLV_NRD_NRD_1 1130 1132 PF00675 0.437
CLV_NRD_NRD_1 1183 1185 PF00675 0.449
CLV_NRD_NRD_1 1198 1200 PF00675 0.346
CLV_NRD_NRD_1 1216 1218 PF00675 0.297
CLV_NRD_NRD_1 1224 1226 PF00675 0.392
CLV_NRD_NRD_1 124 126 PF00675 0.656
CLV_NRD_NRD_1 1273 1275 PF00675 0.460
CLV_NRD_NRD_1 1312 1314 PF00675 0.670
CLV_NRD_NRD_1 140 142 PF00675 0.482
CLV_NRD_NRD_1 1421 1423 PF00675 0.436
CLV_NRD_NRD_1 1475 1477 PF00675 0.578
CLV_NRD_NRD_1 1501 1503 PF00675 0.631
CLV_NRD_NRD_1 17 19 PF00675 0.637
CLV_NRD_NRD_1 340 342 PF00675 0.411
CLV_NRD_NRD_1 547 549 PF00675 0.570
CLV_NRD_NRD_1 559 561 PF00675 0.504
CLV_NRD_NRD_1 633 635 PF00675 0.519
CLV_NRD_NRD_1 859 861 PF00675 0.501
CLV_NRD_NRD_1 95 97 PF00675 0.665
CLV_NRD_NRD_1 998 1000 PF00675 0.367
CLV_PCSK_FUR_1 1499 1503 PF00082 0.618
CLV_PCSK_KEX2_1 1043 1045 PF00082 0.424
CLV_PCSK_KEX2_1 1059 1061 PF00082 0.293
CLV_PCSK_KEX2_1 1130 1132 PF00082 0.437
CLV_PCSK_KEX2_1 1183 1185 PF00082 0.449
CLV_PCSK_KEX2_1 1216 1218 PF00082 0.421
CLV_PCSK_KEX2_1 1224 1226 PF00082 0.392
CLV_PCSK_KEX2_1 123 125 PF00082 0.672
CLV_PCSK_KEX2_1 1273 1275 PF00082 0.460
CLV_PCSK_KEX2_1 1311 1313 PF00082 0.669
CLV_PCSK_KEX2_1 140 142 PF00082 0.461
CLV_PCSK_KEX2_1 1420 1422 PF00082 0.546
CLV_PCSK_KEX2_1 1499 1501 PF00082 0.628
CLV_PCSK_KEX2_1 17 19 PF00082 0.637
CLV_PCSK_KEX2_1 1722 1724 PF00082 0.507
CLV_PCSK_KEX2_1 340 342 PF00082 0.411
CLV_PCSK_KEX2_1 549 551 PF00082 0.495
CLV_PCSK_KEX2_1 559 561 PF00082 0.395
CLV_PCSK_KEX2_1 633 635 PF00082 0.519
CLV_PCSK_KEX2_1 859 861 PF00082 0.501
CLV_PCSK_KEX2_1 97 99 PF00082 0.662
CLV_PCSK_KEX2_1 998 1000 PF00082 0.367
CLV_PCSK_PC1ET2_1 1043 1045 PF00082 0.424
CLV_PCSK_PC1ET2_1 1059 1061 PF00082 0.293
CLV_PCSK_PC1ET2_1 123 125 PF00082 0.606
CLV_PCSK_PC1ET2_1 1722 1724 PF00082 0.474
CLV_PCSK_PC1ET2_1 549 551 PF00082 0.495
CLV_PCSK_PC1ET2_1 97 99 PF00082 0.662
CLV_PCSK_PC7_1 1718 1724 PF00082 0.463
CLV_PCSK_PC7_1 629 635 PF00082 0.502
CLV_PCSK_SKI1_1 1087 1091 PF00082 0.377
CLV_PCSK_SKI1_1 1146 1150 PF00082 0.413
CLV_PCSK_SKI1_1 1274 1278 PF00082 0.459
CLV_PCSK_SKI1_1 1356 1360 PF00082 0.396
CLV_PCSK_SKI1_1 1421 1425 PF00082 0.435
CLV_PCSK_SKI1_1 254 258 PF00082 0.378
CLV_PCSK_SKI1_1 306 310 PF00082 0.422
CLV_PCSK_SKI1_1 340 344 PF00082 0.394
CLV_PCSK_SKI1_1 407 411 PF00082 0.438
CLV_PCSK_SKI1_1 421 425 PF00082 0.411
CLV_PCSK_SKI1_1 452 456 PF00082 0.477
CLV_PCSK_SKI1_1 746 750 PF00082 0.528
CLV_PCSK_SKI1_1 771 775 PF00082 0.459
CLV_PCSK_SKI1_1 859 863 PF00082 0.500
CLV_PCSK_SKI1_1 950 954 PF00082 0.429
DEG_APCC_DBOX_1 1186 1194 PF00400 0.485
DEG_APCC_DBOX_1 1229 1237 PF00400 0.536
DEG_APCC_DBOX_1 451 459 PF00400 0.475
DEG_APCC_DBOX_1 664 672 PF00400 0.422
DEG_APCC_DBOX_1 710 718 PF00400 0.467
DEG_SCF_FBW7_1 1539 1546 PF00400 0.524
DEG_SPOP_SBC_1 111 115 PF00917 0.636
DEG_SPOP_SBC_1 485 489 PF00917 0.411
DEG_SPOP_SBC_1 565 569 PF00917 0.512
DEG_SPOP_SBC_1 82 86 PF00917 0.606
DOC_ANK_TNKS_1 1446 1453 PF00023 0.476
DOC_CKS1_1 1203 1208 PF01111 0.454
DOC_CKS1_1 1262 1267 PF01111 0.495
DOC_CKS1_1 1411 1416 PF01111 0.472
DOC_CKS1_1 1540 1545 PF01111 0.549
DOC_CKS1_1 42 47 PF01111 0.541
DOC_CKS1_1 701 706 PF01111 0.519
DOC_CKS1_1 840 845 PF01111 0.514
DOC_CKS1_1 976 981 PF01111 0.345
DOC_CYCLIN_RxL_1 1353 1361 PF00134 0.347
DOC_CYCLIN_RxL_1 1595 1605 PF00134 0.311
DOC_CYCLIN_RxL_1 1617 1628 PF00134 0.402
DOC_CYCLIN_RxL_1 251 260 PF00134 0.380
DOC_CYCLIN_RxL_1 313 326 PF00134 0.361
DOC_CYCLIN_RxL_1 404 414 PF00134 0.439
DOC_CYCLIN_yCln2_LP_2 1011 1017 PF00134 0.398
DOC_CYCLIN_yCln2_LP_2 1411 1417 PF00134 0.471
DOC_MAPK_DCC_7 1595 1603 PF00069 0.380
DOC_MAPK_gen_1 1127 1137 PF00069 0.448
DOC_MAPK_gen_1 1180 1190 PF00069 0.457
DOC_MAPK_gen_1 1273 1281 PF00069 0.424
DOC_MAPK_gen_1 559 565 PF00069 0.546
DOC_MAPK_gen_1 633 641 PF00069 0.459
DOC_MAPK_gen_1 96 105 PF00069 0.630
DOC_MAPK_HePTP_8 320 332 PF00069 0.275
DOC_MAPK_JIP1_4 711 717 PF00069 0.464
DOC_MAPK_MEF2A_6 1216 1223 PF00069 0.476
DOC_MAPK_MEF2A_6 1273 1281 PF00069 0.445
DOC_MAPK_MEF2A_6 1599 1606 PF00069 0.298
DOC_MAPK_MEF2A_6 323 332 PF00069 0.274
DOC_MAPK_MEF2A_6 633 641 PF00069 0.459
DOC_MAPK_MEF2A_6 711 718 PF00069 0.467
DOC_MAPK_MEF2A_6 96 105 PF00069 0.630
DOC_MAPK_MEF2A_6 982 991 PF00069 0.388
DOC_MAPK_RevD_3 1707 1723 PF00069 0.413
DOC_MAPK_RevD_3 328 341 PF00069 0.359
DOC_PP1_RVXF_1 1134 1140 PF00149 0.459
DOC_PP1_RVXF_1 1354 1361 PF00149 0.347
DOC_PP1_RVXF_1 339 346 PF00149 0.419
DOC_PP2B_LxvP_1 1588 1591 PF13499 0.530
DOC_PP2B_LxvP_1 211 214 PF13499 0.510
DOC_PP4_FxxP_1 13 16 PF00568 0.637
DOC_PP4_FxxP_1 849 852 PF00568 0.477
DOC_PP4_MxPP_1 934 937 PF00568 0.503
DOC_USP7_MATH_1 1022 1026 PF00917 0.286
DOC_USP7_MATH_1 104 108 PF00917 0.676
DOC_USP7_MATH_1 1119 1123 PF00917 0.502
DOC_USP7_MATH_1 1141 1145 PF00917 0.469
DOC_USP7_MATH_1 1249 1253 PF00917 0.602
DOC_USP7_MATH_1 1299 1303 PF00917 0.537
DOC_USP7_MATH_1 134 138 PF00917 0.651
DOC_USP7_MATH_1 1367 1371 PF00917 0.351
DOC_USP7_MATH_1 1372 1376 PF00917 0.386
DOC_USP7_MATH_1 1458 1462 PF00917 0.588
DOC_USP7_MATH_1 1577 1581 PF00917 0.580
DOC_USP7_MATH_1 16 20 PF00917 0.667
DOC_USP7_MATH_1 196 200 PF00917 0.539
DOC_USP7_MATH_1 22 26 PF00917 0.667
DOC_USP7_MATH_1 45 49 PF00917 0.635
DOC_USP7_MATH_1 574 578 PF00917 0.599
DOC_USP7_MATH_1 601 605 PF00917 0.672
DOC_USP7_MATH_1 637 641 PF00917 0.379
DOC_USP7_MATH_1 71 75 PF00917 0.614
DOC_USP7_MATH_1 728 732 PF00917 0.637
DOC_USP7_MATH_1 735 739 PF00917 0.627
DOC_USP7_MATH_1 801 805 PF00917 0.678
DOC_USP7_MATH_1 82 86 PF00917 0.613
DOC_USP7_MATH_1 919 923 PF00917 0.483
DOC_USP7_MATH_1 940 944 PF00917 0.525
DOC_WW_Pin1_4 1028 1033 PF00397 0.424
DOC_WW_Pin1_4 107 112 PF00397 0.533
DOC_WW_Pin1_4 1114 1119 PF00397 0.497
DOC_WW_Pin1_4 1152 1157 PF00397 0.590
DOC_WW_Pin1_4 1160 1165 PF00397 0.494
DOC_WW_Pin1_4 1202 1207 PF00397 0.453
DOC_WW_Pin1_4 1261 1266 PF00397 0.622
DOC_WW_Pin1_4 132 137 PF00397 0.631
DOC_WW_Pin1_4 1368 1373 PF00397 0.413
DOC_WW_Pin1_4 1390 1395 PF00397 0.496
DOC_WW_Pin1_4 1410 1415 PF00397 0.470
DOC_WW_Pin1_4 1539 1544 PF00397 0.577
DOC_WW_Pin1_4 1579 1584 PF00397 0.438
DOC_WW_Pin1_4 1622 1627 PF00397 0.402
DOC_WW_Pin1_4 217 222 PF00397 0.526
DOC_WW_Pin1_4 375 380 PF00397 0.547
DOC_WW_Pin1_4 391 396 PF00397 0.359
DOC_WW_Pin1_4 41 46 PF00397 0.539
DOC_WW_Pin1_4 5 10 PF00397 0.689
DOC_WW_Pin1_4 511 516 PF00397 0.540
DOC_WW_Pin1_4 570 575 PF00397 0.579
DOC_WW_Pin1_4 609 614 PF00397 0.549
DOC_WW_Pin1_4 627 632 PF00397 0.313
DOC_WW_Pin1_4 67 72 PF00397 0.682
DOC_WW_Pin1_4 700 705 PF00397 0.527
DOC_WW_Pin1_4 733 738 PF00397 0.640
DOC_WW_Pin1_4 759 764 PF00397 0.521
DOC_WW_Pin1_4 839 844 PF00397 0.519
DOC_WW_Pin1_4 848 853 PF00397 0.413
DOC_WW_Pin1_4 975 980 PF00397 0.389
LIG_14-3-3_CanoR_1 1187 1191 PF00244 0.480
LIG_14-3-3_CanoR_1 1296 1304 PF00244 0.539
LIG_14-3-3_CanoR_1 1671 1675 PF00244 0.384
LIG_14-3-3_CanoR_1 1718 1724 PF00244 0.505
LIG_14-3-3_CanoR_1 195 205 PF00244 0.485
LIG_14-3-3_CanoR_1 243 248 PF00244 0.370
LIG_14-3-3_CanoR_1 254 260 PF00244 0.355
LIG_14-3-3_CanoR_1 273 277 PF00244 0.580
LIG_14-3-3_CanoR_1 310 316 PF00244 0.336
LIG_14-3-3_CanoR_1 407 417 PF00244 0.340
LIG_14-3-3_CanoR_1 447 455 PF00244 0.474
LIG_14-3-3_CanoR_1 559 564 PF00244 0.493
LIG_14-3-3_CanoR_1 60 66 PF00244 0.623
LIG_14-3-3_CanoR_1 618 623 PF00244 0.530
LIG_14-3-3_CanoR_1 665 671 PF00244 0.421
LIG_14-3-3_CanoR_1 729 735 PF00244 0.626
LIG_14-3-3_CanoR_1 859 869 PF00244 0.453
LIG_14-3-3_CanoR_1 883 893 PF00244 0.508
LIG_14-3-3_CanoR_1 916 926 PF00244 0.523
LIG_AP2alpha_2 11 13 PF02296 0.701
LIG_BIR_II_1 1 5 PF00653 0.693
LIG_BRCT_BRCA1_1 1143 1147 PF00533 0.452
LIG_BRCT_BRCA1_1 821 825 PF00533 0.495
LIG_BRCT_BRCA1_1 885 889 PF00533 0.524
LIG_BRCT_BRCA1_1 948 952 PF00533 0.443
LIG_CSL_BTD_1 563 566 PF09270 0.468
LIG_CtBP_PxDLS_1 1408 1412 PF00389 0.460
LIG_deltaCOP1_diTrp_1 1361 1368 PF00928 0.353
LIG_deltaCOP1_diTrp_1 1397 1404 PF00928 0.496
LIG_deltaCOP1_diTrp_1 291 295 PF00928 0.490
LIG_EVH1_1 840 844 PF00568 0.450
LIG_FHA_1 133 139 PF00498 0.516
LIG_FHA_1 1393 1399 PF00498 0.603
LIG_FHA_1 1410 1416 PF00498 0.440
LIG_FHA_1 1515 1521 PF00498 0.508
LIG_FHA_1 1540 1546 PF00498 0.564
LIG_FHA_1 1549 1555 PF00498 0.455
LIG_FHA_1 1585 1591 PF00498 0.535
LIG_FHA_1 1626 1632 PF00498 0.407
LIG_FHA_1 1686 1692 PF00498 0.385
LIG_FHA_1 1719 1725 PF00498 0.517
LIG_FHA_1 376 382 PF00498 0.406
LIG_FHA_1 479 485 PF00498 0.554
LIG_FHA_1 487 493 PF00498 0.466
LIG_FHA_1 512 518 PF00498 0.561
LIG_FHA_1 523 529 PF00498 0.442
LIG_FHA_1 636 642 PF00498 0.444
LIG_FHA_1 696 702 PF00498 0.549
LIG_FHA_1 951 957 PF00498 0.451
LIG_FHA_2 1080 1086 PF00498 0.487
LIG_FHA_2 1296 1302 PF00498 0.506
LIG_FHA_2 1434 1440 PF00498 0.449
LIG_FHA_2 146 152 PF00498 0.590
LIG_FHA_2 1545 1551 PF00498 0.489
LIG_FHA_2 258 264 PF00498 0.480
LIG_FHA_2 852 858 PF00498 0.440
LIG_FHA_2 862 868 PF00498 0.391
LIG_GSK3_LRP6_1 1390 1395 PF00069 0.471
LIG_Integrin_isoDGR_2 788 790 PF01839 0.537
LIG_LIR_Apic_2 10 16 PF02991 0.636
LIG_LIR_Apic_2 1361 1367 PF02991 0.394
LIG_LIR_Apic_2 1592 1597 PF02991 0.490
LIG_LIR_Apic_2 837 843 PF02991 0.525
LIG_LIR_Gen_1 1063 1073 PF02991 0.407
LIG_LIR_Gen_1 1215 1226 PF02991 0.348
LIG_LIR_Gen_1 1672 1682 PF02991 0.361
LIG_LIR_Gen_1 326 334 PF02991 0.404
LIG_LIR_Gen_1 431 440 PF02991 0.455
LIG_LIR_Gen_1 540 546 PF02991 0.539
LIG_LIR_Gen_1 822 831 PF02991 0.393
LIG_LIR_Gen_1 891 901 PF02991 0.463
LIG_LIR_Nem_3 1063 1068 PF02991 0.414
LIG_LIR_Nem_3 1215 1221 PF02991 0.338
LIG_LIR_Nem_3 1338 1344 PF02991 0.383
LIG_LIR_Nem_3 1361 1366 PF02991 0.384
LIG_LIR_Nem_3 1636 1641 PF02991 0.381
LIG_LIR_Nem_3 326 330 PF02991 0.406
LIG_LIR_Nem_3 431 436 PF02991 0.433
LIG_LIR_Nem_3 540 545 PF02991 0.544
LIG_LIR_Nem_3 672 678 PF02991 0.487
LIG_LIR_Nem_3 822 828 PF02991 0.545
LIG_LIR_Nem_3 891 897 PF02991 0.470
LIG_LIR_Nem_3 978 984 PF02991 0.383
LIG_LIR_Nem_3 988 994 PF02991 0.294
LIG_MYND_1 12 16 PF01753 0.637
LIG_MYND_1 515 519 PF01753 0.466
LIG_NRBOX 1006 1012 PF00104 0.402
LIG_NRBOX 1189 1195 PF00104 0.498
LIG_NRBOX 303 309 PF00104 0.424
LIG_NRBOX 713 719 PF00104 0.469
LIG_NRP_CendR_1 1722 1725 PF00754 0.527
LIG_OCRL_FandH_1 314 326 PF00620 0.383
LIG_PALB2_WD40_1 979 987 PF16756 0.388
LIG_PCNA_yPIPBox_3 1689 1697 PF02747 0.384
LIG_PCNA_yPIPBox_3 998 1011 PF02747 0.408
LIG_Pex14_1 1364 1368 PF04695 0.267
LIG_Pex14_1 1400 1404 PF04695 0.531
LIG_Pex14_2 632 636 PF04695 0.517
LIG_Rb_LxCxE_1 384 401 PF01857 0.398
LIG_Rb_pABgroove_1 888 896 PF01858 0.488
LIG_SH2_CRK 542 546 PF00017 0.535
LIG_SH2_CRK 894 898 PF00017 0.449
LIG_SH2_NCK_1 1000 1004 PF00017 0.420
LIG_SH2_NCK_1 1012 1016 PF00017 0.287
LIG_SH2_NCK_1 1061 1065 PF00017 0.419
LIG_SH2_NCK_1 542 546 PF00017 0.535
LIG_SH2_SRC 1000 1003 PF00017 0.393
LIG_SH2_SRC 1012 1015 PF00017 0.313
LIG_SH2_SRC 1061 1064 PF00017 0.462
LIG_SH2_SRC 1713 1716 PF00017 0.405
LIG_SH2_SRC 658 661 PF00017 0.461
LIG_SH2_STAP1 1035 1039 PF00017 0.437
LIG_SH2_STAP1 1061 1065 PF00017 0.462
LIG_SH2_STAP1 1516 1520 PF00017 0.595
LIG_SH2_STAP1 561 565 PF00017 0.500
LIG_SH2_STAP1 894 898 PF00017 0.449
LIG_SH2_STAT3 1182 1185 PF00017 0.294
LIG_SH2_STAT5 1176 1179 PF00017 0.429
LIG_SH2_STAT5 1287 1290 PF00017 0.467
LIG_SH2_STAT5 1443 1446 PF00017 0.450
LIG_SH2_STAT5 1516 1519 PF00017 0.592
LIG_SH2_STAT5 1623 1626 PF00017 0.402
LIG_SH2_STAT5 236 239 PF00017 0.392
LIG_SH2_STAT5 555 558 PF00017 0.636
LIG_SH2_STAT5 658 661 PF00017 0.461
LIG_SH2_STAT5 869 872 PF00017 0.440
LIG_SH3_1 1608 1614 PF00018 0.399
LIG_SH3_3 1026 1032 PF00018 0.359
LIG_SH3_3 1134 1140 PF00018 0.393
LIG_SH3_3 1243 1249 PF00018 0.533
LIG_SH3_3 1259 1265 PF00018 0.502
LIG_SH3_3 1272 1278 PF00018 0.454
LIG_SH3_3 1366 1372 PF00018 0.384
LIG_SH3_3 1385 1391 PF00018 0.525
LIG_SH3_3 1469 1475 PF00018 0.583
LIG_SH3_3 1534 1540 PF00018 0.534
LIG_SH3_3 1580 1586 PF00018 0.449
LIG_SH3_3 1594 1600 PF00018 0.375
LIG_SH3_3 1608 1614 PF00018 0.315
LIG_SH3_3 1676 1682 PF00018 0.385
LIG_SH3_3 376 382 PF00018 0.538
LIG_SH3_3 48 54 PF00018 0.628
LIG_SH3_3 513 519 PF00018 0.471
LIG_SH3_3 560 566 PF00018 0.502
LIG_SH3_3 593 599 PF00018 0.534
LIG_SH3_3 6 12 PF00018 0.694
LIG_SH3_3 654 660 PF00018 0.459
LIG_SH3_3 698 704 PF00018 0.538
LIG_SH3_3 769 775 PF00018 0.499
LIG_SH3_3 838 844 PF00018 0.457
LIG_SH3_3 933 939 PF00018 0.502
LIG_Sin3_3 1064 1071 PF02671 0.405
LIG_SUMO_SIM_anti_2 1165 1171 PF11976 0.464
LIG_SUMO_SIM_anti_2 1280 1285 PF11976 0.414
LIG_SUMO_SIM_anti_2 1549 1557 PF11976 0.416
LIG_SUMO_SIM_anti_2 201 206 PF11976 0.459
LIG_SUMO_SIM_par_1 1406 1413 PF11976 0.591
LIG_SUMO_SIM_par_1 1586 1592 PF11976 0.529
LIG_SUMO_SIM_par_1 255 260 PF11976 0.415
LIG_SUMO_SIM_par_1 637 642 PF11976 0.438
LIG_SUMO_SIM_par_1 714 720 PF11976 0.474
LIG_SUMO_SIM_par_1 850 857 PF11976 0.364
LIG_TRAF2_1 1436 1439 PF00917 0.447
LIG_TRAF2_1 264 267 PF00917 0.509
LIG_TRAF2_1 854 857 PF00917 0.451
LIG_TYR_ITIM 1010 1015 PF00017 0.398
LIG_UBA3_1 1193 1200 PF00899 0.387
LIG_UBA3_1 1606 1613 PF00899 0.274
LIG_ULM_U2AF65_1 1043 1048 PF00076 0.441
LIG_WRC_WIRS_1 451 456 PF05994 0.476
MOD_CDC14_SPxK_1 630 633 PF00782 0.454
MOD_CDK_SPK_2 1579 1584 PF00069 0.438
MOD_CDK_SPK_2 609 614 PF00069 0.510
MOD_CDK_SPK_2 67 72 PF00069 0.595
MOD_CDK_SPxK_1 627 633 PF00069 0.445
MOD_CDK_SPxxK_3 511 518 PF00069 0.537
MOD_CDK_SPxxK_3 627 634 PF00069 0.449
MOD_CDK_SPxxK_3 975 982 PF00069 0.389
MOD_CK1_1 1031 1037 PF00069 0.434
MOD_CK1_1 107 113 PF00069 0.662
MOD_CK1_1 1101 1107 PF00069 0.391
MOD_CK1_1 1117 1123 PF00069 0.434
MOD_CK1_1 1163 1169 PF00069 0.450
MOD_CK1_1 1295 1301 PF00069 0.619
MOD_CK1_1 132 138 PF00069 0.629
MOD_CK1_1 1546 1552 PF00069 0.512
MOD_CK1_1 1625 1631 PF00069 0.406
MOD_CK1_1 1649 1655 PF00069 0.254
MOD_CK1_1 1662 1668 PF00069 0.218
MOD_CK1_1 215 221 PF00069 0.538
MOD_CK1_1 298 304 PF00069 0.391
MOD_CK1_1 351 357 PF00069 0.477
MOD_CK1_1 429 435 PF00069 0.510
MOD_CK1_1 537 543 PF00069 0.489
MOD_CK1_1 577 583 PF00069 0.573
MOD_CK1_1 736 742 PF00069 0.671
MOD_CK1_1 810 816 PF00069 0.461
MOD_CK1_1 851 857 PF00069 0.451
MOD_CK1_1 922 928 PF00069 0.494
MOD_CK1_1 959 965 PF00069 0.437
MOD_CK2_1 1318 1324 PF00069 0.548
MOD_CK2_1 1433 1439 PF00069 0.450
MOD_CK2_1 1489 1495 PF00069 0.607
MOD_CK2_1 1500 1506 PF00069 0.581
MOD_CK2_1 1524 1530 PF00069 0.572
MOD_CK2_1 1544 1550 PF00069 0.372
MOD_CK2_1 262 268 PF00069 0.501
MOD_CK2_1 293 299 PF00069 0.447
MOD_CK2_1 431 437 PF00069 0.455
MOD_CK2_1 67 73 PF00069 0.641
MOD_CK2_1 728 734 PF00069 0.658
MOD_CK2_1 851 857 PF00069 0.451
MOD_CK2_1 861 867 PF00069 0.382
MOD_Cter_Amidation 546 549 PF01082 0.503
MOD_GlcNHglycan 1 4 PF01048 0.696
MOD_GlcNHglycan 1024 1027 PF01048 0.412
MOD_GlcNHglycan 106 109 PF01048 0.548
MOD_GlcNHglycan 1121 1124 PF01048 0.564
MOD_GlcNHglycan 1143 1146 PF01048 0.474
MOD_GlcNHglycan 1240 1244 PF01048 0.540
MOD_GlcNHglycan 1249 1252 PF01048 0.524
MOD_GlcNHglycan 1265 1268 PF01048 0.482
MOD_GlcNHglycan 131 134 PF01048 0.608
MOD_GlcNHglycan 1320 1323 PF01048 0.621
MOD_GlcNHglycan 1378 1381 PF01048 0.541
MOD_GlcNHglycan 1401 1404 PF01048 0.529
MOD_GlcNHglycan 143 146 PF01048 0.481
MOD_GlcNHglycan 155 158 PF01048 0.447
MOD_GlcNHglycan 1575 1578 PF01048 0.559
MOD_GlcNHglycan 1635 1638 PF01048 0.383
MOD_GlcNHglycan 1648 1651 PF01048 0.262
MOD_GlcNHglycan 1666 1669 PF01048 0.246
MOD_GlcNHglycan 198 201 PF01048 0.481
MOD_GlcNHglycan 214 217 PF01048 0.457
MOD_GlcNHglycan 284 287 PF01048 0.429
MOD_GlcNHglycan 295 298 PF01048 0.314
MOD_GlcNHglycan 353 356 PF01048 0.543
MOD_GlcNHglycan 428 431 PF01048 0.488
MOD_GlcNHglycan 47 50 PF01048 0.654
MOD_GlcNHglycan 494 497 PF01048 0.531
MOD_GlcNHglycan 520 523 PF01048 0.477
MOD_GlcNHglycan 576 579 PF01048 0.609
MOD_GlcNHglycan 61 64 PF01048 0.545
MOD_GlcNHglycan 624 627 PF01048 0.468
MOD_GlcNHglycan 661 664 PF01048 0.460
MOD_GlcNHglycan 687 690 PF01048 0.526
MOD_GlcNHglycan 802 806 PF01048 0.574
MOD_GlcNHglycan 86 89 PF01048 0.651
MOD_GlcNHglycan 919 922 PF01048 0.523
MOD_GlcNHglycan 995 998 PF01048 0.404
MOD_GSK3_1 107 114 PF00069 0.642
MOD_GSK3_1 1291 1298 PF00069 0.462
MOD_GSK3_1 132 139 PF00069 0.633
MOD_GSK3_1 1368 1375 PF00069 0.374
MOD_GSK3_1 141 148 PF00069 0.534
MOD_GSK3_1 1458 1465 PF00069 0.502
MOD_GSK3_1 1510 1517 PF00069 0.455
MOD_GSK3_1 1535 1542 PF00069 0.589
MOD_GSK3_1 1544 1551 PF00069 0.451
MOD_GSK3_1 1569 1576 PF00069 0.597
MOD_GSK3_1 16 23 PF00069 0.693
MOD_GSK3_1 1680 1687 PF00069 0.342
MOD_GSK3_1 220 227 PF00069 0.382
MOD_GSK3_1 344 351 PF00069 0.561
MOD_GSK3_1 40 47 PF00069 0.650
MOD_GSK3_1 424 431 PF00069 0.495
MOD_GSK3_1 446 453 PF00069 0.454
MOD_GSK3_1 484 491 PF00069 0.530
MOD_GSK3_1 518 525 PF00069 0.614
MOD_GSK3_1 565 572 PF00069 0.538
MOD_GSK3_1 577 584 PF00069 0.536
MOD_GSK3_1 601 608 PF00069 0.548
MOD_GSK3_1 618 625 PF00069 0.441
MOD_GSK3_1 67 74 PF00069 0.597
MOD_GSK3_1 77 84 PF00069 0.531
MOD_GSK3_1 810 817 PF00069 0.462
MOD_GSK3_1 847 854 PF00069 0.452
MOD_GSK3_1 884 891 PF00069 0.489
MOD_GSK3_1 922 929 PF00069 0.458
MOD_GSK3_1 946 953 PF00069 0.465
MOD_N-GLC_1 1053 1058 PF02516 0.437
MOD_N-GLC_1 1101 1106 PF02516 0.417
MOD_N-GLC_1 1114 1119 PF02516 0.369
MOD_N-GLC_1 1152 1157 PF02516 0.599
MOD_N-GLC_1 1291 1296 PF02516 0.402
MOD_N-GLC_1 570 575 PF02516 0.513
MOD_N-GLC_1 792 797 PF02516 0.643
MOD_N-GLC_1 807 812 PF02516 0.453
MOD_N-GLC_2 1004 1006 PF02516 0.418
MOD_NEK2_1 1100 1105 PF00069 0.415
MOD_NEK2_1 1194 1199 PF00069 0.454
MOD_NEK2_1 1399 1404 PF00069 0.534
MOD_NEK2_1 1409 1414 PF00069 0.373
MOD_NEK2_1 1524 1529 PF00069 0.482
MOD_NEK2_1 1544 1549 PF00069 0.450
MOD_NEK2_1 1633 1638 PF00069 0.385
MOD_NEK2_1 1643 1648 PF00069 0.292
MOD_NEK2_1 1670 1675 PF00069 0.369
MOD_NEK2_1 1685 1690 PF00069 0.262
MOD_NEK2_1 257 262 PF00069 0.397
MOD_NEK2_1 408 413 PF00069 0.403
MOD_NEK2_1 454 459 PF00069 0.444
MOD_NEK2_1 492 497 PF00069 0.505
MOD_NEK2_1 717 722 PF00069 0.467
MOD_NEK2_1 748 753 PF00069 0.560
MOD_NEK2_1 807 812 PF00069 0.529
MOD_NEK2_1 814 819 PF00069 0.490
MOD_NEK2_1 893 898 PF00069 0.454
MOD_NEK2_1 952 957 PF00069 0.413
MOD_NEK2_1 993 998 PF00069 0.401
MOD_PIKK_1 1462 1468 PF00454 0.502
MOD_PIKK_1 335 341 PF00454 0.402
MOD_PIKK_1 794 800 PF00454 0.620
MOD_PIKK_1 834 840 PF00454 0.504
MOD_PIKK_1 861 867 PF00454 0.453
MOD_PIKK_1 950 956 PF00454 0.400
MOD_PK_1 1569 1575 PF00069 0.564
MOD_PK_1 243 249 PF00069 0.264
MOD_PK_1 501 507 PF00069 0.409
MOD_PK_1 559 565 PF00069 0.496
MOD_PK_1 618 624 PF00069 0.415
MOD_PKA_1 1313 1319 PF00069 0.634
MOD_PKA_1 1500 1506 PF00069 0.635
MOD_PKA_1 17 23 PF00069 0.568
MOD_PKA_1 559 565 PF00069 0.496
MOD_PKA_2 1186 1192 PF00069 0.480
MOD_PKA_2 1295 1301 PF00069 0.575
MOD_PKA_2 1433 1439 PF00069 0.450
MOD_PKA_2 1500 1506 PF00069 0.635
MOD_PKA_2 1524 1530 PF00069 0.507
MOD_PKA_2 16 22 PF00069 0.664
MOD_PKA_2 1670 1676 PF00069 0.384
MOD_PKA_2 1717 1723 PF00069 0.500
MOD_PKA_2 272 278 PF00069 0.618
MOD_PKA_2 446 452 PF00069 0.474
MOD_PKA_2 559 565 PF00069 0.496
MOD_PKA_2 59 65 PF00069 0.685
MOD_PKA_2 617 623 PF00069 0.547
MOD_PKA_2 728 734 PF00069 0.658
MOD_PKB_1 1311 1319 PF00069 0.675
MOD_PKB_1 881 889 PF00069 0.529
MOD_Plk_1 1529 1535 PF00069 0.569
MOD_Plk_1 1549 1555 PF00069 0.375
MOD_Plk_1 1577 1583 PF00069 0.576
MOD_Plk_2-3 1186 1192 PF00069 0.480
MOD_Plk_2-3 1451 1457 PF00069 0.458
MOD_Plk_4 1336 1342 PF00069 0.474
MOD_Plk_4 1549 1555 PF00069 0.470
MOD_Plk_4 220 226 PF00069 0.366
MOD_Plk_4 435 441 PF00069 0.456
MOD_Plk_4 537 543 PF00069 0.538
MOD_Plk_4 559 565 PF00069 0.496
MOD_Plk_4 584 590 PF00069 0.639
MOD_Plk_4 618 624 PF00069 0.415
MOD_Plk_4 653 659 PF00069 0.457
MOD_Plk_4 666 672 PF00069 0.348
MOD_Plk_4 703 709 PF00069 0.471
MOD_Plk_4 810 816 PF00069 0.524
MOD_Plk_4 885 891 PF00069 0.475
MOD_Plk_4 893 899 PF00069 0.422
MOD_Plk_4 959 965 PF00069 0.443
MOD_ProDKin_1 1028 1034 PF00069 0.426
MOD_ProDKin_1 107 113 PF00069 0.531
MOD_ProDKin_1 1114 1120 PF00069 0.502
MOD_ProDKin_1 1152 1158 PF00069 0.590
MOD_ProDKin_1 1160 1166 PF00069 0.486
MOD_ProDKin_1 1202 1208 PF00069 0.453
MOD_ProDKin_1 1261 1267 PF00069 0.624
MOD_ProDKin_1 132 138 PF00069 0.629
MOD_ProDKin_1 1368 1374 PF00069 0.420
MOD_ProDKin_1 1390 1396 PF00069 0.490
MOD_ProDKin_1 1410 1416 PF00069 0.470
MOD_ProDKin_1 1539 1545 PF00069 0.572
MOD_ProDKin_1 1579 1585 PF00069 0.435
MOD_ProDKin_1 1622 1628 PF00069 0.403
MOD_ProDKin_1 217 223 PF00069 0.519
MOD_ProDKin_1 375 381 PF00069 0.543
MOD_ProDKin_1 391 397 PF00069 0.359
MOD_ProDKin_1 41 47 PF00069 0.541
MOD_ProDKin_1 5 11 PF00069 0.691
MOD_ProDKin_1 511 517 PF00069 0.539
MOD_ProDKin_1 570 576 PF00069 0.586
MOD_ProDKin_1 609 615 PF00069 0.547
MOD_ProDKin_1 627 633 PF00069 0.317
MOD_ProDKin_1 67 73 PF00069 0.680
MOD_ProDKin_1 700 706 PF00069 0.523
MOD_ProDKin_1 733 739 PF00069 0.638
MOD_ProDKin_1 759 765 PF00069 0.519
MOD_ProDKin_1 839 845 PF00069 0.518
MOD_ProDKin_1 848 854 PF00069 0.412
MOD_ProDKin_1 975 981 PF00069 0.389
MOD_SUMO_for_1 1448 1451 PF00179 0.478
MOD_SUMO_for_1 1518 1521 PF00179 0.541
MOD_SUMO_rev_2 1451 1459 PF00179 0.441
MOD_SUMO_rev_2 1673 1682 PF00179 0.385
MOD_SUMO_rev_2 738 748 PF00179 0.583
TRG_DiLeu_BaEn_1 1550 1555 PF01217 0.475
TRG_DiLeu_BaEn_1 193 198 PF01217 0.566
TRG_DiLeu_BaEn_1 299 304 PF01217 0.415
TRG_DiLeu_BaEn_2 449 455 PF01217 0.475
TRG_DiLeu_BaLyEn_6 1189 1194 PF01217 0.498
TRG_DiLeu_BaLyEn_6 1540 1545 PF01217 0.569
TRG_DiLeu_BaLyEn_6 1599 1604 PF01217 0.432
TRG_DiLeu_BaLyEn_6 1614 1619 PF01217 0.256
TRG_DiLeu_BaLyEn_6 303 308 PF01217 0.425
TRG_DiLeu_BaLyEn_6 376 381 PF01217 0.541
TRG_DiLeu_BaLyEn_6 404 409 PF01217 0.427
TRG_DiLeu_BaLyEn_6 989 994 PF01217 0.392
TRG_ENDOCYTIC_2 1012 1015 PF00928 0.399
TRG_ENDOCYTIC_2 1075 1078 PF00928 0.493
TRG_ENDOCYTIC_2 1363 1366 PF00928 0.395
TRG_ENDOCYTIC_2 542 545 PF00928 0.540
TRG_ENDOCYTIC_2 894 897 PF00928 0.451
TRG_ENDOCYTIC_2 981 984 PF00928 0.387
TRG_ER_diArg_1 1130 1133 PF00400 0.457
TRG_ER_diArg_1 1182 1184 PF00400 0.292
TRG_ER_diArg_1 1216 1218 PF00400 0.421
TRG_ER_diArg_1 1223 1225 PF00400 0.401
TRG_ER_diArg_1 124 126 PF00400 0.620
TRG_ER_diArg_1 1273 1275 PF00400 0.460
TRG_ER_diArg_1 1311 1313 PF00400 0.645
TRG_ER_diArg_1 1419 1422 PF00400 0.444
TRG_ER_diArg_1 1499 1502 PF00400 0.621
TRG_ER_diArg_1 16 18 PF00400 0.638
TRG_ER_diArg_1 340 342 PF00400 0.411
TRG_ER_diArg_1 559 561 PF00400 0.488
TRG_ER_diArg_1 58 61 PF00400 0.673
TRG_ER_diArg_1 632 634 PF00400 0.513
TRG_ER_diArg_1 858 860 PF00400 0.467
TRG_ER_diArg_1 998 1000 PF00400 0.367
TRG_NLS_Bipartite_1 1183 1203 PF00514 0.439
TRG_NLS_MonoExtN_4 1040 1047 PF00514 0.428
TRG_Pf-PMV_PEXEL_1 1235 1240 PF00026 0.450
TRG_Pf-PMV_PEXEL_1 1356 1361 PF00026 0.346
TRG_Pf-PMV_PEXEL_1 1422 1426 PF00026 0.434
TRG_Pf-PMV_PEXEL_1 147 151 PF00026 0.547
TRG_Pf-PMV_PEXEL_1 243 248 PF00026 0.351
TRG_Pf-PMV_PEXEL_1 465 469 PF00026 0.476
TRG_Pf-PMV_PEXEL_1 554 558 PF00026 0.494
TRG_Pf-PMV_PEXEL_1 860 865 PF00026 0.499

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7XB18 Leishmania donovani 89% 99%
A4HPC8 Leishmania braziliensis 68% 99%
A4ICG8 Leishmania infantum 89% 99%
E9AT39 Leishmania mexicana (strain MHOM/GT/2001/U1103) 85% 99%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS