LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania major
UniProt:
Q4Q1E6_LEIMA
TriTrypDb:
LmjF.36.2740 * , LMJLV39_360036300 , LMJSD75_360036200
Length:
1019

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q1E6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q1E6

Function

Biological processes
TermNameLevelCount
GO:0006807 nitrogen compound metabolic process 2 6
GO:0008152 metabolic process 1 6
GO:0009308 amine metabolic process 4 6
GO:0071704 organic substance metabolic process 2 6
GO:1901564 organonitrogen compound metabolic process 3 6
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Molecular functions
TermNameLevelCount
GO:0003824 catalytic activity 1 6
GO:0005488 binding 1 6
GO:0005507 copper ion binding 6 6
GO:0008131 primary amine oxidase activity 5 6
GO:0016491 oxidoreductase activity 2 6
GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 3 6
GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 4 6
GO:0043167 ion binding 2 6
GO:0043169 cation binding 3 6
GO:0046872 metal ion binding 4 6
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 1014 1016 PF00675 0.548
CLV_NRD_NRD_1 313 315 PF00675 0.527
CLV_NRD_NRD_1 324 326 PF00675 0.622
CLV_NRD_NRD_1 452 454 PF00675 0.421
CLV_NRD_NRD_1 887 889 PF00675 0.469
CLV_NRD_NRD_1 998 1000 PF00675 0.537
CLV_PCSK_FUR_1 1012 1016 PF00082 0.614
CLV_PCSK_FUR_1 310 314 PF00082 0.532
CLV_PCSK_KEX2_1 1014 1016 PF00082 0.548
CLV_PCSK_KEX2_1 312 314 PF00082 0.521
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I662 Leptomonas seymouri 49% 92%
A0A3S7XB33 Leishmania donovani 95% 100%
A4HPE0 Leishmania braziliensis 82% 100%
A4ICI1 Leishmania infantum 94% 100%
E9AT52 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS