LeishMANIAdb
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DUF4164 family protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
DUF4164 family protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q1D5_LEIMA
TriTrypDb:
LmjF.36.2845 , LMJLV39_360037500 * , LMJSD75_360037400
Length:
92

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q1D5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q1D5

Putative motif mimicry

Leishmania From To Domain/Motif Score
DOC_USP7_UBL2_3 55 59 PF12436 0.536
LIG_BIR_II_1 1 5 PF00653 0.460
LIG_FHA_1 41 47 PF00498 0.476
LIG_FHA_1 71 77 PF00498 0.543
LIG_FHA_2 1 7 PF00498 0.453
MOD_CK1_1 60 66 PF00069 0.562
MOD_CK1_1 70 76 PF00069 0.502
MOD_GlcNHglycan 67 70 PF01048 0.625
MOD_GlcNHglycan 80 83 PF01048 0.544
MOD_GSK3_1 57 64 PF00069 0.473
MOD_NEK2_1 57 62 PF00069 0.531
MOD_NEK2_1 67 72 PF00069 0.529
MOD_PIKK_1 67 73 PF00454 0.521
MOD_PKA_2 60 66 PF00069 0.591
TRG_ER_diArg_1 14 17 PF00400 0.459

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I666 Leptomonas seymouri 49% 98%
A0A3Q8IG76 Leishmania donovani 96% 100%
A4HPF1 Leishmania braziliensis 83% 100%
A4ICJ2 Leishmania infantum 96% 100%
D0A3G0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 97%
E9AT62 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS