ATP pyrophosphate-lyase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q194_LEIMA

TriTrypDb:

LmjF.36.3240 , LMJLV39_360042300 , LMJSD75_360042200

Length:

291

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4Q194

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q194

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	31	33	PF00675	0.609
CLV_PCSK_FUR_1	29	33	PF00082	0.619
CLV_PCSK_KEX2_1	29	31	PF00082	0.631
CLV_PCSK_SKI1_1	124	128	PF00082	0.801
DEG_Nend_UBRbox_2	1	3	PF02207	0.849
DEG_SCF_FBW7_1	205	212	PF00400	0.570
DOC_ANK_TNKS_1	149	156	PF00023	0.606
DOC_MAPK_gen_1	78	87	PF00069	0.650
DOC_MAPK_MEF2A_6	78	87	PF00069	0.650
DOC_PP1_RVXF_1	212	219	PF00149	0.601
DOC_USP7_MATH_1	126	130	PF00917	0.596
DOC_USP7_MATH_1	165	169	PF00917	0.585
DOC_USP7_MATH_1	191	195	PF00917	0.618
DOC_USP7_MATH_1	22	26	PF00917	0.829
DOC_USP7_MATH_1	240	244	PF00917	0.611
DOC_WW_Pin1_4	205	210	PF00397	0.618
DOC_WW_Pin1_4	4	9	PF00397	0.829
LIG_14-3-3_CanoR_1	124	134	PF00244	0.594
LIG_14-3-3_CanoR_1	67	76	PF00244	0.778
LIG_APCC_ABBAyCdc20_2	41	47	PF00400	0.788
LIG_BRCT_BRCA1_1	193	197	PF00533	0.627
LIG_BRCT_BRCA1_1	214	218	PF00533	0.595
LIG_BRCT_BRCA1_1	69	73	PF00533	0.776
LIG_FHA_1	118	124	PF00498	0.606
LIG_FHA_1	129	135	PF00498	0.450
LIG_FHA_1	158	164	PF00498	0.597
LIG_FHA_1	181	187	PF00498	0.597
LIG_FHA_1	86	92	PF00498	0.549
LIG_FHA_2	206	212	PF00498	0.624
LIG_FHA_2	55	61	PF00498	0.798
LIG_LIR_Gen_1	125	134	PF02991	0.593
LIG_LIR_Gen_1	143	153	PF02991	0.367
LIG_LIR_Gen_1	164	173	PF02991	0.584
LIG_LIR_Gen_1	70	80	PF02991	0.780
LIG_LIR_Nem_3	125	130	PF02991	0.598
LIG_LIR_Nem_3	164	169	PF02991	0.582
LIG_LIR_Nem_3	199	205	PF02991	0.631
LIG_LIR_Nem_3	70	76	PF02991	0.775
LIG_LYPXL_S_1	36	40	PF13949	0.595
LIG_LYPXL_yS_3	37	40	PF13949	0.797
LIG_PTB_Apo_2	39	46	PF02174	0.792
LIG_PTB_Phospho_1	39	45	PF10480	0.797
LIG_REV1ctd_RIR_1	93	101	PF16727	0.549
LIG_SH2_SRC	282	285	PF00017	0.641
LIG_SH2_STAP1	98	102	PF00017	0.720
LIG_SH2_STAT3	246	249	PF00017	0.617
LIG_SH2_STAT3	98	101	PF00017	0.718
LIG_SH2_STAT5	246	249	PF00017	0.617
LIG_SH2_STAT5	282	285	PF00017	0.641
LIG_SH2_STAT5	68	71	PF00017	0.782
LIG_SH2_STAT5	75	78	PF00017	0.693
LIG_SH3_3	74	80	PF00018	0.781
LIG_SUMO_SIM_anti_2	51	58	PF11976	0.804
LIG_SUMO_SIM_anti_2	88	95	PF11976	0.549
LIG_SUMO_SIM_par_1	253	260	PF11976	0.643
LIG_SUMO_SIM_par_1	51	58	PF11976	0.804
LIG_UBA3_1	91	97	PF00899	0.549
LIG_WRC_WIRS_1	127	132	PF05994	0.593
MOD_CDK_SPxxK_3	4	11	PF00069	0.828
MOD_CK1_1	125	131	PF00069	0.595
MOD_CK1_1	221	227	PF00069	0.578
MOD_CK1_1	256	262	PF00069	0.645
MOD_CK2_1	112	118	PF00069	0.610
MOD_CK2_1	126	132	PF00069	0.419
MOD_CK2_1	205	211	PF00069	0.621
MOD_CK2_1	4	10	PF00069	0.829
MOD_CK2_1	43	49	PF00069	0.786
MOD_GlcNHglycan	114	117	PF01048	0.813
MOD_GlcNHglycan	124	127	PF01048	0.678
MOD_GlcNHglycan	264	267	PF01048	0.840
MOD_GlcNHglycan	269	272	PF01048	0.785
MOD_GSK3_1	122	129	PF00069	0.602
MOD_GSK3_1	157	164	PF00069	0.597
MOD_GSK3_1	191	198	PF00069	0.623
MOD_GSK3_1	205	212	PF00069	0.445
MOD_GSK3_1	218	225	PF00069	0.454
MOD_GSK3_1	228	235	PF00069	0.482
MOD_GSK3_1	253	260	PF00069	0.643
MOD_N-GLC_1	209	214	PF02516	0.814
MOD_N-GLC_1	23	28	PF02516	0.630
MOD_NEK2_1	267	272	PF00069	0.648
MOD_NEK2_1	40	45	PF00069	0.794
MOD_NEK2_1	85	90	PF00069	0.549
MOD_NEK2_2	119	124	PF00069	0.604
MOD_NEK2_2	192	197	PF00069	0.625
MOD_PKA_2	149	155	PF00069	0.605
MOD_Plk_1	212	218	PF00069	0.602
MOD_Plk_1	222	228	PF00069	0.454
MOD_Plk_4	165	171	PF00069	0.586
MOD_Plk_4	173	179	PF00069	0.491
MOD_Plk_4	192	198	PF00069	0.389
MOD_Plk_4	40	46	PF00069	0.790
MOD_Plk_4	86	92	PF00069	0.549
MOD_ProDKin_1	205	211	PF00069	0.621
MOD_ProDKin_1	4	10	PF00069	0.829
TRG_DiLeu_BaEn_4	132	138	PF01217	0.586
TRG_ENDOCYTIC_2	37	40	PF00928	0.797
TRG_ER_diArg_1	28	31	PF00400	0.832
TRG_Pf-PMV_PEXEL_1	67	71	PF00026	0.584