Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q180_LEIMA

TriTrypDb:

LmjF.36.3380 , LMJLV39_360043900 , LMJSD75_360043800

Length:

138


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0110165	cellular anatomical entity	1	3
GO:0016020	membrane	2	1

Q4Q180

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q180


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	10	12	PF00675	0.590
CLV_NRD_NRD_1	3	5	PF00675	0.586
CLV_PCSK_KEX2_1	10	12	PF00082	0.590
CLV_PCSK_KEX2_1	3	5	PF00082	0.586
CLV_PCSK_SKI1_1	54	58	PF00082	0.550
DEG_Nend_Nbox_1	1	3	PF02207	0.431
LIG_14-3-3_CanoR_1	10	20	PF00244	0.308
LIG_14-3-3_CanoR_1	3	9	PF00244	0.431
LIG_BRCT_BRCA1_1	44	48	PF00533	0.357
LIG_BRCT_BRCA1_1	52	56	PF00533	0.398
LIG_FHA_1	27	33	PF00498	0.398
LIG_FHA_1	65	71	PF00498	0.423
LIG_FHA_2	23	29	PF00498	0.363
LIG_LIR_Gen_1	45	56	PF02991	0.335
LIG_LIR_Nem_3	45	51	PF02991	0.334
LIG_SH2_STAT5	69	72	PF00017	0.368
LIG_SH3_3	107	113	PF00018	0.584
LIG_SH3_3	86	92	PF00018	0.351
LIG_SUMO_SIM_par_1	28	34	PF11976	0.284
LIG_TRAF2_1	133	136	PF00917	0.608
LIG_TRAF2_1	25	28	PF00917	0.457
MOD_CK1_1	42	48	PF00069	0.346
MOD_CK2_1	22	28	PF00069	0.364
MOD_GlcNHglycan	13	16	PF01048	0.641
MOD_GlcNHglycan	79	82	PF01048	0.565
MOD_GSK3_1	22	29	PF00069	0.394
MOD_GSK3_1	39	46	PF00069	0.302
MOD_NEK2_1	2	7	PF00069	0.400
MOD_NEK2_1	26	31	PF00069	0.361
MOD_NEK2_1	50	55	PF00069	0.349
MOD_PK_1	4	10	PF00069	0.539
MOD_PKA_1	3	9	PF00069	0.479
MOD_PKA_2	102	108	PF00069	0.569
MOD_PKA_2	2	8	PF00069	0.399
MOD_Plk_1	64	70	PF00069	0.416
MOD_Plk_4	39	45	PF00069	0.424
MOD_Plk_4	4	10	PF00069	0.526
MOD_SUMO_for_1	115	118	PF00179	0.652
TRG_ER_diArg_1	2	4	PF00400	0.396
TRG_ER_diArg_1	9	11	PF00400	0.395
TRG_NES_CRM1_1	39	52	PF08389	0.356
TRG_Pf-PMV_PEXEL_1	107	111	PF00026	0.440


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZE1	Leptomonas seymouri	67%	100%
A0A0S4JIS2	Bodo saltans	32%	100%
A0A1X0P4N6	Trypanosomatidae	52%	100%
A0A3Q8IJB8	Leishmania donovani	96%	100%
A0A3S5IS04	Trypanosoma rangeli	53%	98%
A4HPK5	Leishmania braziliensis	84%	100%
A4ID59	Leishmania infantum	96%	100%
D0A8K8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	56%	100%
E9ATB7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%