60S ribosomal protein L29

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ribosomal protein L29, putative

Species:

Leishmania major

UniProt:

Q4Q178_LEIMA

TriTrypDb:

LmjF.36.3400 , LMJLV39_360044100 , LMJSD75_360043900

Length:

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0015934	large ribosomal subunit	4	2
GO:0022625	cytosolic large ribosomal subunit	5	2
GO:0032991	protein-containing complex	1	10
GO:0044391	ribosomal subunit	3	2
GO:1990904	ribonucleoprotein complex	2	10
GO:0005840	ribosome	5	8
GO:0043226	organelle	2	8
GO:0043228	non-membrane-bounded organelle	3	8
GO:0043229	intracellular organelle	3	8
GO:0043232	intracellular non-membrane-bounded organelle	4	8
GO:0110165	cellular anatomical entity	1	8

Expansion

Sequence features

Q4Q178

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q178

Function

Biological processes
Term	Name	Level	Count
GO:0002181	cytoplasmic translation	5	2
GO:0006412	translation	4	10
GO:0006518	peptide metabolic process	4	10
GO:0006807	nitrogen compound metabolic process	2	10
GO:0008152	metabolic process	1	10
GO:0009058	biosynthetic process	2	10
GO:0009059	macromolecule biosynthetic process	4	10
GO:0009987	cellular process	1	10
GO:0019538	protein metabolic process	3	10
GO:0034641	cellular nitrogen compound metabolic process	3	10
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	10
GO:0043043	peptide biosynthetic process	5	10
GO:0043170	macromolecule metabolic process	3	10
GO:0043603	amide metabolic process	3	10
GO:0043604	amide biosynthetic process	4	10
GO:0044237	cellular metabolic process	2	10
GO:0044238	primary metabolic process	2	10
GO:0044249	cellular biosynthetic process	3	10
GO:0044260	obsolete cellular macromolecule metabolic process	3	10
GO:0044271	cellular nitrogen compound biosynthetic process	4	10
GO:0071704	organic substance metabolic process	2	10
GO:1901564	organonitrogen compound metabolic process	3	10
GO:1901566	organonitrogen compound biosynthetic process	4	10
GO:1901576	organic substance biosynthetic process	3	10

Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	10
GO:0005198	structural molecule activity	1	10

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	45	47	PF00675	0.509
CLV_NRD_NRD_1	59	61	PF00675	0.518
CLV_PCSK_KEX2_1	33	35	PF00082	0.534
CLV_PCSK_KEX2_1	45	47	PF00082	0.473
CLV_PCSK_KEX2_1	58	60	PF00082	0.527
CLV_PCSK_PC1ET2_1	33	35	PF00082	0.549
CLV_PCSK_PC1ET2_1	58	60	PF00082	0.606
CLV_PCSK_SKI1_1	53	57	PF00082	0.556
DOC_MAPK_MEF2A_6	22	29	PF00069	0.356
DOC_USP7_UBL2_3	49	53	PF12436	0.516
LIG_BIR_II_1	1	5	PF00653	0.344
MOD_GSK3_1	1	8	PF00069	0.324
MOD_GSK3_1	29	36	PF00069	0.490
MOD_N-GLC_1	5	10	PF02516	0.344
MOD_NEK2_1	1	6	PF00069	0.344
MOD_NEK2_1	29	34	PF00069	0.513
MOD_PKA_1	33	39	PF00069	0.575
MOD_PKA_2	33	39	PF00069	0.509
MOD_Plk_4	33	39	PF00069	0.492
TRG_ER_diArg_1	45	48	PF00400	0.510

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5Z8	Leptomonas seymouri	94%	100%
A0A0S4JE25	Bodo saltans	78%	97%
A0A3Q8IJK1	Leishmania donovani	99%	100%
A4HPK6	Leishmania braziliensis	93%	100%
A4ID57	Leishmania infantum	96%	100%
A4ID58	Leishmania infantum	99%	100%
D0A8K6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	81%	99%
E9ATB8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	100%	100%
Q24154	Drosophila melanogaster	49%	92%
Q84WM0	Arabidopsis thaliana	56%	100%
Q9M7X7	Arabidopsis thaliana	58%	100%