Oxoglutarate dehydrogenase (succinyl-transferring)

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

2-oxoglutarate dehydrogenase E1 component, putative

Species:

Leishmania major

UniProt:

Q4Q171_LEIMA

TriTrypDb:

LmjF.36.3470 , LMJLV39_360044900 , LMJSD75_360044800

Length:

979

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 16

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 2, no: 11
NetGPI	no	yes: 0, no: 13

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0005739	mitochondrion	5	2
GO:0005815	microtubule organizing center	2	2
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	2
GO:0032991	protein-containing complex	1	2
GO:0036064	ciliary basal body	3	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0045239	tricarboxylic acid cycle enzyme complex	3	2
GO:0045240	dihydrolipoyl dehydrogenase complex	4	2
GO:0045252	oxoglutarate dehydrogenase complex	4	2
GO:0097014	ciliary plasm	5	2
GO:0099568	cytoplasmic region	3	2
GO:0110165	cellular anatomical entity	1	2
GO:1902494	catalytic complex	2	2
GO:1990204	oxidoreductase complex	3	2
GO:1990234	transferase complex	3	2

Expansion

Sequence features

Q4Q171

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q171

Function

Biological processes
Term	Name	Level	Count
GO:0006099	tricarboxylic acid cycle	3	14
GO:0008152	metabolic process	1	14
GO:0044238	primary metabolic process	2	14

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	14
GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	5	14
GO:0005488	binding	1	14
GO:0016491	oxidoreductase activity	2	14
GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	4	14
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	3	14
GO:0019842	vitamin binding	3	14
GO:0030976	thiamine pyrophosphate binding	3	14
GO:0036094	small molecule binding	2	14
GO:0043167	ion binding	2	14
GO:0043168	anion binding	3	14
GO:0043169	cation binding	3	14
GO:0050997	quaternary ammonium group binding	2	14
GO:0097159	organic cyclic compound binding	2	14
GO:1901363	heterocyclic compound binding	2	14
GO:1901681	sulfur compound binding	2	14

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	195	199	PF00656	0.515
CLV_C14_Caspase3-7	208	212	PF00656	0.439
CLV_NRD_NRD_1	127	129	PF00675	0.439
CLV_NRD_NRD_1	243	245	PF00675	0.242
CLV_NRD_NRD_1	4	6	PF00675	0.575
CLV_NRD_NRD_1	485	487	PF00675	0.225
CLV_NRD_NRD_1	514	516	PF00675	0.298
CLV_NRD_NRD_1	616	618	PF00675	0.370
CLV_NRD_NRD_1	813	815	PF00675	0.225
CLV_NRD_NRD_1	820	822	PF00675	0.225
CLV_NRD_NRD_1	864	866	PF00675	0.225
CLV_PCSK_KEX2_1	127	129	PF00082	0.499
CLV_PCSK_KEX2_1	200	202	PF00082	0.477
CLV_PCSK_KEX2_1	243	245	PF00082	0.256
CLV_PCSK_KEX2_1	250	252	PF00082	0.236
CLV_PCSK_KEX2_1	3	5	PF00082	0.595
CLV_PCSK_KEX2_1	485	487	PF00082	0.225
CLV_PCSK_KEX2_1	514	516	PF00082	0.309
CLV_PCSK_KEX2_1	616	618	PF00082	0.384
CLV_PCSK_KEX2_1	813	815	PF00082	0.225
CLV_PCSK_KEX2_1	817	819	PF00082	0.225
CLV_PCSK_KEX2_1	864	866	PF00082	0.240
CLV_PCSK_PC1ET2_1	200	202	PF00082	0.482
CLV_PCSK_PC1ET2_1	243	245	PF00082	0.256
CLV_PCSK_PC1ET2_1	250	252	PF00082	0.236
CLV_PCSK_PC1ET2_1	817	819	PF00082	0.340
CLV_PCSK_PC7_1	123	129	PF00082	0.473
CLV_PCSK_PC7_1	813	819	PF00082	0.253
CLV_PCSK_SKI1_1	13	17	PF00082	0.589
CLV_PCSK_SKI1_1	265	269	PF00082	0.340
CLV_PCSK_SKI1_1	567	571	PF00082	0.386
CLV_PCSK_SKI1_1	592	596	PF00082	0.498
CLV_PCSK_SKI1_1	611	615	PF00082	0.249
CLV_PCSK_SKI1_1	821	825	PF00082	0.300
CLV_PCSK_SKI1_1	884	888	PF00082	0.333
CLV_PCSK_SKI1_1	952	956	PF00082	0.317
CLV_Separin_Metazoa	131	135	PF03568	0.430
DEG_APCC_DBOX_1	285	293	PF00400	0.425
DEG_SCF_FBW7_1	525	531	PF00400	0.440
DEG_SCF_FBW7_1	781	787	PF00400	0.442
DOC_CKS1_1	525	530	PF01111	0.540
DOC_CKS1_1	66	71	PF01111	0.629
DOC_CKS1_1	781	786	PF01111	0.442
DOC_CKS1_1	802	807	PF01111	0.425
DOC_CYCLIN_RxL_1	10	21	PF00134	0.581
DOC_CYCLIN_yCln2_LP_2	66	72	PF00134	0.541
DOC_MAPK_DCC_7	374	384	PF00069	0.544
DOC_MAPK_gen_1	127	137	PF00069	0.372
DOC_MAPK_gen_1	200	209	PF00069	0.479
DOC_MAPK_gen_1	374	382	PF00069	0.528
DOC_MAPK_gen_1	470	479	PF00069	0.453
DOC_MAPK_gen_1	817	828	PF00069	0.442
DOC_MAPK_gen_1	881	891	PF00069	0.540
DOC_MAPK_MEF2A_6	128	137	PF00069	0.373
DOC_MAPK_MEF2A_6	376	384	PF00069	0.509
DOC_MAPK_MEF2A_6	442	451	PF00069	0.467
DOC_MAPK_MEF2A_6	472	481	PF00069	0.453
DOC_MAPK_MEF2A_6	821	828	PF00069	0.432
DOC_MAPK_RevD_3	604	617	PF00069	0.421
DOC_PP1_RVXF_1	11	18	PF00149	0.551
DOC_PP1_RVXF_1	150	156	PF00149	0.400
DOC_PP1_RVXF_1	184	190	PF00149	0.429
DOC_PP1_RVXF_1	792	798	PF00149	0.540
DOC_PP2B_LxvP_1	833	836	PF13499	0.526
DOC_PP2B_LxvP_1	856	859	PF13499	0.440
DOC_USP7_MATH_1	428	432	PF00917	0.425
DOC_USP7_MATH_1	435	439	PF00917	0.425
DOC_USP7_MATH_1	528	532	PF00917	0.574
DOC_USP7_MATH_1	636	640	PF00917	0.449
DOC_USP7_MATH_1	739	743	PF00917	0.467
DOC_USP7_MATH_1	74	78	PF00917	0.535
DOC_USP7_MATH_1	763	767	PF00917	0.425
DOC_USP7_MATH_1	836	840	PF00917	0.343
DOC_USP7_MATH_1	950	954	PF00917	0.439
DOC_USP7_MATH_1	956	960	PF00917	0.413
DOC_USP7_UBL2_3	374	378	PF12436	0.440
DOC_WW_Pin1_4	121	126	PF00397	0.450
DOC_WW_Pin1_4	164	169	PF00397	0.557
DOC_WW_Pin1_4	524	529	PF00397	0.524
DOC_WW_Pin1_4	65	70	PF00397	0.599
DOC_WW_Pin1_4	690	695	PF00397	0.504
DOC_WW_Pin1_4	780	785	PF00397	0.436
DOC_WW_Pin1_4	801	806	PF00397	0.425
DOC_WW_Pin1_4	895	900	PF00397	0.446
LIG_14-3-3_CanoR_1	201	209	PF00244	0.382
LIG_14-3-3_CanoR_1	244	252	PF00244	0.452
LIG_14-3-3_CanoR_1	432	440	PF00244	0.443
LIG_14-3-3_CanoR_1	472	478	PF00244	0.516
LIG_14-3-3_CanoR_1	514	521	PF00244	0.458
LIG_14-3-3_CanoR_1	95	101	PF00244	0.354
LIG_AP2alpha_1	238	242	PF02296	0.442
LIG_APCC_ABBA_1	382	387	PF00400	0.425
LIG_BRCT_BRCA1_1	233	237	PF00533	0.299
LIG_BRCT_BRCA1_1	845	849	PF00533	0.517
LIG_Clathr_ClatBox_1	891	895	PF01394	0.442
LIG_deltaCOP1_diTrp_1	46	53	PF00928	0.442
LIG_EH_1	356	360	PF12763	0.540
LIG_eIF4E_1	710	716	PF01652	0.467
LIG_eIF4E_1	912	918	PF01652	0.442
LIG_FHA_1	108	114	PF00498	0.502
LIG_FHA_1	342	348	PF00498	0.468
LIG_FHA_1	397	403	PF00498	0.439
LIG_FHA_1	411	417	PF00498	0.401
LIG_FHA_1	496	502	PF00498	0.442
LIG_FHA_1	515	521	PF00498	0.390
LIG_FHA_1	711	717	PF00498	0.471
LIG_FHA_1	868	874	PF00498	0.432
LIG_FHA_1	881	887	PF00498	0.417
LIG_FHA_2	193	199	PF00498	0.394
LIG_FHA_2	309	315	PF00498	0.453
LIG_FHA_2	597	603	PF00498	0.424
LIG_FHA_2	648	654	PF00498	0.535
LIG_FHA_2	838	844	PF00498	0.351
LIG_FHA_2	939	945	PF00498	0.553
LIG_FHA_2	97	103	PF00498	0.342
LIG_LIR_Gen_1	46	53	PF02991	0.450
LIG_LIR_Gen_1	730	739	PF02991	0.467
LIG_LIR_Gen_1	771	781	PF02991	0.485
LIG_LIR_Gen_1	929	937	PF02991	0.553
LIG_LIR_Nem_3	136	142	PF02991	0.387
LIG_LIR_Nem_3	306	310	PF02991	0.444
LIG_LIR_Nem_3	46	52	PF02991	0.431
LIG_LIR_Nem_3	511	516	PF02991	0.455
LIG_LIR_Nem_3	672	678	PF02991	0.469
LIG_LIR_Nem_3	696	701	PF02991	0.442
LIG_LIR_Nem_3	719	725	PF02991	0.451
LIG_LIR_Nem_3	730	736	PF02991	0.425
LIG_LIR_Nem_3	846	852	PF02991	0.424
LIG_LIR_Nem_3	929	933	PF02991	0.553
LIG_NRBOX	174	180	PF00104	0.488
LIG_NRBOX	263	269	PF00104	0.540
LIG_PAM2_1	800	812	PF00658	0.453
LIG_PCNA_yPIPBox_3	587	598	PF02747	0.366
LIG_PCNA_yPIPBox_3	963	977	PF02747	0.471
LIG_Pex14_1	49	53	PF04695	0.442
LIG_Pex14_1	718	722	PF04695	0.425
LIG_Pex14_1	797	801	PF04695	0.467
LIG_Pex14_2	237	241	PF04695	0.287
LIG_PTB_Apo_2	16	23	PF02174	0.583
LIG_REV1ctd_RIR_1	239	249	PF16727	0.442
LIG_REV1ctd_RIR_1	825	835	PF16727	0.425
LIG_SH2_CRK	444	448	PF00017	0.506
LIG_SH2_CRK	698	702	PF00017	0.447
LIG_SH2_CRK	874	878	PF00017	0.453
LIG_SH2_GRB2like	876	879	PF00017	0.471
LIG_SH2_NCK_1	912	916	PF00017	0.485
LIG_SH2_PTP2	675	678	PF00017	0.467
LIG_SH2_SRC	545	548	PF00017	0.557
LIG_SH2_STAP1	363	367	PF00017	0.462
LIG_SH2_STAP1	516	520	PF00017	0.442
LIG_SH2_STAP1	554	558	PF00017	0.355
LIG_SH2_STAP1	571	575	PF00017	0.390
LIG_SH2_STAT3	246	249	PF00017	0.432
LIG_SH2_STAT3	330	333	PF00017	0.561
LIG_SH2_STAT5	115	118	PF00017	0.475
LIG_SH2_STAT5	139	142	PF00017	0.462
LIG_SH2_STAT5	183	186	PF00017	0.317
LIG_SH2_STAT5	363	366	PF00017	0.449
LIG_SH2_STAT5	436	439	PF00017	0.432
LIG_SH2_STAT5	516	519	PF00017	0.558
LIG_SH2_STAT5	557	560	PF00017	0.435
LIG_SH2_STAT5	675	678	PF00017	0.443
LIG_SH2_STAT5	808	811	PF00017	0.455
LIG_SH2_STAT5	832	835	PF00017	0.529
LIG_SH2_STAT5	876	879	PF00017	0.471
LIG_SH2_STAT5	940	943	PF00017	0.434
LIG_SH3_3	749	755	PF00018	0.485
LIG_SH3_3	778	784	PF00018	0.442
LIG_SH3_3	799	805	PF00018	0.434
LIG_SH3_3	848	854	PF00018	0.463
LIG_SUMO_SIM_anti_2	888	893	PF11976	0.427
LIG_TRAF2_1	221	224	PF00917	0.405
LIG_TRAF2_1	311	314	PF00917	0.471
LIG_TRAF2_1	544	547	PF00917	0.396
LIG_TRAF2_1	787	790	PF00917	0.485
LIG_TRAF2_1	840	843	PF00917	0.508
LIG_TRAF2_1	920	923	PF00917	0.442
LIG_TRFH_1	604	608	PF08558	0.415
LIG_TYR_ITIM	501	506	PF00017	0.442
LIG_WRC_WIRS_1	97	102	PF05994	0.461
MOD_CDK_SPxK_1	121	127	PF00069	0.485
MOD_CDK_SPxxK_3	121	128	PF00069	0.455
MOD_CK1_1	21	27	PF00069	0.462
MOD_CK1_1	430	436	PF00069	0.427
MOD_CK1_1	693	699	PF00069	0.474
MOD_CK2_1	202	208	PF00069	0.489
MOD_CK2_1	218	224	PF00069	0.274
MOD_CK2_1	308	314	PF00069	0.445
MOD_CK2_1	348	354	PF00069	0.439
MOD_CK2_1	367	373	PF00069	0.529
MOD_CK2_1	45	51	PF00069	0.503
MOD_CK2_1	541	547	PF00069	0.474
MOD_CK2_1	596	602	PF00069	0.426
MOD_CK2_1	735	741	PF00069	0.425
MOD_CK2_1	74	80	PF00069	0.515
MOD_CK2_1	784	790	PF00069	0.452
MOD_CK2_1	836	842	PF00069	0.279
MOD_CK2_1	938	944	PF00069	0.511
MOD_CK2_1	961	967	PF00069	0.477
MOD_Cter_Amidation	1	4	PF01082	0.708
MOD_GlcNHglycan	213	216	PF01048	0.469
MOD_GlcNHglycan	23	26	PF01048	0.261
MOD_GlcNHglycan	233	236	PF01048	0.197
MOD_GlcNHglycan	337	340	PF01048	0.340
MOD_GlcNHglycan	433	436	PF01048	0.253
MOD_GlcNHglycan	737	740	PF01048	0.243
MOD_GlcNHglycan	766	769	PF01048	0.231
MOD_GlcNHglycan	845	848	PF01048	0.240
MOD_GSK3_1	164	171	PF00069	0.374
MOD_GSK3_1	396	403	PF00069	0.426
MOD_GSK3_1	41	48	PF00069	0.468
MOD_GSK3_1	423	430	PF00069	0.494
MOD_GSK3_1	431	438	PF00069	0.401
MOD_GSK3_1	524	531	PF00069	0.501
MOD_GSK3_1	576	583	PF00069	0.459
MOD_GSK3_1	667	674	PF00069	0.515
MOD_GSK3_1	735	742	PF00069	0.433
MOD_GSK3_1	746	753	PF00069	0.410
MOD_GSK3_1	775	782	PF00069	0.456
MOD_GSK3_1	797	804	PF00069	0.521
MOD_GSK3_1	854	861	PF00069	0.470
MOD_GSK3_1	952	959	PF00069	0.429
MOD_N-GLC_1	18	23	PF02516	0.343
MOD_N-GLC_1	576	581	PF02516	0.403
MOD_N-GLC_1	617	622	PF02516	0.433
MOD_N-GLC_1	690	695	PF02516	0.287
MOD_N-GLC_1	836	841	PF02516	0.330
MOD_NEK2_1	202	207	PF00069	0.469
MOD_NEK2_1	23	28	PF00069	0.448
MOD_NEK2_1	367	372	PF00069	0.471
MOD_NEK2_1	473	478	PF00069	0.434
MOD_NEK2_1	558	563	PF00069	0.411
MOD_NEK2_2	168	173	PF00069	0.297
MOD_NEK2_2	705	710	PF00069	0.540
MOD_PIKK_1	202	208	PF00454	0.374
MOD_PIKK_1	245	251	PF00454	0.425
MOD_PIKK_1	495	501	PF00454	0.425
MOD_PIKK_1	519	525	PF00454	0.518
MOD_PIKK_1	529	535	PF00454	0.473
MOD_PIKK_1	576	582	PF00454	0.452
MOD_PIKK_1	583	589	PF00454	0.348
MOD_PIKK_1	667	673	PF00454	0.475
MOD_PIKK_1	681	687	PF00454	0.508
MOD_PIKK_1	858	864	PF00454	0.517
MOD_PKA_1	244	250	PF00069	0.453
MOD_PKA_1	514	520	PF00069	0.493
MOD_PKA_2	431	437	PF00069	0.427
MOD_PKA_2	514	520	PF00069	0.495
MOD_PKA_2	647	653	PF00069	0.438
MOD_PKA_2	655	661	PF00069	0.409
MOD_PKA_2	880	886	PF00069	0.540
MOD_Plk_1	18	24	PF00069	0.343
MOD_Plk_1	45	51	PF00069	0.467
MOD_Plk_1	617	623	PF00069	0.439
MOD_Plk_1	671	677	PF00069	0.538
MOD_Plk_1	797	803	PF00069	0.521
MOD_Plk_1	836	842	PF00069	0.259
MOD_Plk_1	854	860	PF00069	0.425
MOD_Plk_2-3	41	47	PF00069	0.453
MOD_Plk_4	18	24	PF00069	0.302
MOD_Plk_4	256	262	PF00069	0.442
MOD_Plk_4	473	479	PF00069	0.448
MOD_Plk_4	636	642	PF00069	0.442
MOD_Plk_4	705	711	PF00069	0.477
MOD_Plk_4	727	733	PF00069	0.475
MOD_ProDKin_1	121	127	PF00069	0.447
MOD_ProDKin_1	164	170	PF00069	0.551
MOD_ProDKin_1	524	530	PF00069	0.524
MOD_ProDKin_1	65	71	PF00069	0.592
MOD_ProDKin_1	690	696	PF00069	0.504
MOD_ProDKin_1	780	786	PF00069	0.436
MOD_ProDKin_1	801	807	PF00069	0.425
MOD_ProDKin_1	895	901	PF00069	0.446
MOD_SUMO_rev_2	196	202	PF00179	0.490
MOD_SUMO_rev_2	531	540	PF00179	0.440
MOD_SUMO_rev_2	922	927	PF00179	0.468
TRG_DiLeu_BaEn_1	904	909	PF01217	0.442
TRG_DiLeu_BaEn_1	913	918	PF01217	0.442
TRG_DiLeu_BaLyEn_6	89	94	PF01217	0.365
TRG_ENDOCYTIC_2	129	132	PF00928	0.474
TRG_ENDOCYTIC_2	139	142	PF00928	0.327
TRG_ENDOCYTIC_2	484	487	PF00928	0.464
TRG_ENDOCYTIC_2	503	506	PF00928	0.350
TRG_ENDOCYTIC_2	675	678	PF00928	0.432
TRG_ENDOCYTIC_2	698	701	PF00928	0.442
TRG_ENDOCYTIC_2	722	725	PF00928	0.467
TRG_ENDOCYTIC_2	808	811	PF00928	0.458
TRG_ENDOCYTIC_2	874	877	PF00928	0.452
TRG_ER_diArg_1	127	129	PF00400	0.489
TRG_ER_diArg_1	225	228	PF00400	0.496
TRG_ER_diArg_1	286	289	PF00400	0.425
TRG_ER_diArg_1	3	5	PF00400	0.547
TRG_ER_diArg_1	469	472	PF00400	0.475
TRG_ER_diArg_1	484	486	PF00400	0.373
TRG_ER_diArg_1	513	515	PF00400	0.424
TRG_ER_diArg_1	812	814	PF00400	0.425
TRG_ER_diArg_1	864	866	PF00400	0.442
TRG_Pf-PMV_PEXEL_1	13	18	PF00026	0.570
TRG_Pf-PMV_PEXEL_1	173	177	PF00026	0.386
TRG_Pf-PMV_PEXEL_1	265	269	PF00026	0.253

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HVP3	Leptomonas seymouri	39%	97%
A0A0N1HXR5	Leptomonas seymouri	78%	96%
A0A0S4JH30	Bodo saltans	59%	98%
A0A0S4JV11	Bodo saltans	40%	95%
A0A1X0P3C5	Trypanosomatidae	68%	97%
A0A1X0P407	Trypanosomatidae	41%	97%
A0A3Q8IEB5	Leishmania donovani	40%	97%
A0A3R7KVU5	Trypanosoma rangeli	65%	98%
A0A3S5IR73	Trypanosoma rangeli	41%	97%
A0A3S7XBB9	Leishmania donovani	97%	97%
A0PVU7	Mycobacterium ulcerans (strain Agy99)	37%	79%
A0R2B1	Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)	37%	80%
A1KI36	Mycobacterium bovis (strain BCG / Pasteur 1173P2)	36%	80%
A1TDK2	Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 / PYR-1)	37%	79%
A1UK81	Mycobacterium sp. (strain KMS)	37%	77%
A2ATU0	Mus musculus	37%	100%
A3Q3N5	Mycobacterium sp. (strain JLS)	37%	77%
A4HFL1	Leishmania braziliensis	39%	97%
A4HPL4	Leishmania braziliensis	91%	97%
A4I2P6	Leishmania infantum	40%	97%
A4ID50	Leishmania infantum	97%	97%
A5ISU5	Staphylococcus aureus (strain JH9)	34%	100%
A5U1U6	Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)	36%	80%
A5VSQ0	Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512)	39%	98%
A6QGW6	Staphylococcus aureus (strain Newman)	34%	100%
A6U1N4	Staphylococcus aureus (strain JH1)	34%	100%
A6WXF0	Brucella anthropi (strain ATCC 49188 / DSM 6882 / CCUG 24695 / JCM 21032 / LMG 3331 / NBRC 15819 / NCTC 12168 / Alc 37)	39%	98%
A7GMD4	Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)	37%	100%
A7X295	Staphylococcus aureus (strain Mu3 / ATCC 700698)	34%	100%
A7Z5J9	Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / LMG 26770 / FZB42)	35%	100%
A8FE66	Bacillus pumilus (strain SAFR-032)	35%	100%
A8Z3Z0	Staphylococcus aureus (strain USA300 / TCH1516)	34%	100%
A9M8Q9	Brucella canis (strain ATCC 23365 / NCTC 10854)	38%	98%
A9VJX9	Bacillus mycoides (strain KBAB4)	35%	100%
B0CIS7	Brucella suis (strain ATCC 23445 / NCTC 10510)	38%	98%
B2S877	Brucella abortus (strain S19)	38%	98%
B7HH19	Bacillus cereus (strain B4264)	34%	100%
B7I0H2	Bacillus cereus (strain AH187)	35%	100%
B7IM94	Bacillus cereus (strain G9842)	35%	100%
B7JEU9	Bacillus cereus (strain AH820)	35%	100%
B9IU58	Bacillus cereus (strain Q1)	35%	100%
C0RFG8	Brucella melitensis biotype 2 (strain ATCC 23457)	38%	98%
C1ELG5	Bacillus cereus (strain 03BB102)	35%	100%
C3LAU3	Bacillus anthracis (strain CDC 684 / NRRL 3495)	35%	100%
C3P487	Bacillus anthracis (strain A0248)	35%	100%
C4L3W2	Exiguobacterium sp. (strain ATCC BAA-1283 / AT1b)	36%	100%
C5D802	Geobacillus sp. (strain WCH70)	36%	100%
D0A5T7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	97%
D0A8K0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	63%	97%
D3ZQD3	Rattus norvegicus	40%	97%
E9AD65	Leishmania major	40%	100%
E9ATC6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	97%
E9AYZ0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	97%
O61199	Caenorhabditis elegans	39%	95%
O74378	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	40%	97%
P0AFG3	Escherichia coli (strain K12)	36%	100%
P0AFG4	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	36%	100%
P0AFG5	Escherichia coli O157:H7	36%	100%
P0C601	Staphylococcus aureus	34%	100%
P20707	Azotobacter vinelandii	38%	100%
P20967	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	41%	97%
P23129	Bacillus subtilis (strain 168)	36%	100%
P45303	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	36%	100%
P51056	Coxiella burnetii (strain RSA 493 / Nine Mile phase I)	35%	100%
P57388	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	35%	100%
P9WIS4	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	36%	80%
P9WIS5	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	36%	80%
Q02218	Homo sapiens	38%	96%
Q148N0	Bos taurus	38%	96%
Q1B4V6	Mycobacterium sp. (strain MCS)	37%	77%
Q1RHI4	Rickettsia bellii (strain RML369-C)	36%	100%
Q23629	Caenorhabditis elegans	37%	100%
Q2FH25	Staphylococcus aureus (strain USA300)	34%	100%
Q2FYM1	Staphylococcus aureus (strain NCTC 8325 / PS 47)	34%	100%
Q2YLS2	Brucella abortus (strain 2308)	38%	98%
Q2YY05	Staphylococcus aureus (strain bovine RF122 / ET3-1)	34%	100%
Q49XM5	Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)	34%	100%
Q4KLP0	Rattus norvegicus	39%	100%
Q4L6C4	Staphylococcus haemolyticus (strain JCSC1435)	34%	100%
Q4UKI8	Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)	36%	100%
Q54JE4	Dictyostelium discoideum	40%	97%
Q54VG0	Dictyostelium discoideum	36%	100%
Q57AX5	Brucella abortus biovar 1 (strain 9-941)	38%	98%
Q59106	Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)	38%	100%
Q5HG06	Staphylococcus aureus (strain COL)	34%	100%
Q5HPC6	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	34%	100%
Q5L172	Geobacillus kaustophilus (strain HTA426)	36%	100%
Q5PRA2	Danio rerio	37%	100%
Q5R7H0	Pongo abelii	36%	100%
Q5R9L8	Pongo abelii	40%	97%
Q5RCB8	Pongo abelii	38%	96%
Q5WG56	Alkalihalobacillus clausii (strain KSM-K16)	35%	100%
Q5XI78	Rattus norvegicus	37%	96%
Q60597	Mus musculus	37%	96%
Q60HE2	Macaca fascicularis	38%	96%
Q623T0	Caenorhabditis briggsae	39%	95%
Q63EB1	Bacillus cereus (strain ZK / E33L)	35%	100%
Q65IH4	Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46)	35%	100%
Q68EW0	Xenopus laevis	39%	96%
Q68XI7	Rickettsia typhi (strain ATCC VR-144 / Wilmington)	34%	100%
Q6G9E8	Staphylococcus aureus (strain MSSA476)	34%	100%
Q6GGZ5	Staphylococcus aureus (strain MRSA252)	34%	100%
Q6HLS8	Bacillus thuringiensis subsp. konkukian (strain 97-27)	35%	100%
Q6P286	Xenopus laevis	37%	100%
Q6P6Z8	Xenopus laevis	37%	96%
Q72PJ7	Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)	38%	100%
Q73BN8	Bacillus cereus (strain ATCC 10987 / NRS 248)	35%	100%
Q73WX4	Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)	37%	79%
Q7U0A6	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	36%	80%
Q81GF2	Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)	35%	100%
Q81TK1	Bacillus anthracis	35%	100%
Q89AJ7	Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)	34%	100%
Q8CP83	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	34%	100%
Q8CUL8	Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)	34%	100%
Q8F6S7	Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)	38%	100%
Q8FYF7	Brucella suis biovar 1 (strain 1330)	38%	98%
Q8K9N3	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)	35%	100%
Q8NRC3	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)	37%	80%
Q8NWR6	Staphylococcus aureus (strain MW2)	34%	100%
Q8YJE4	Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)	38%	98%
Q92J42	Rickettsia conorii (strain ATCC VR-613 / Malish 7)	35%	100%
Q931R8	Staphylococcus aureus (strain Mu50 / ATCC 700699)	34%	100%
Q96HY7	Homo sapiens	36%	100%
Q99U74	Staphylococcus aureus (strain N315)	35%	100%
Q9CC97	Mycobacterium leprae (strain TN)	37%	79%
Q9KAT1	Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)	36%	100%
Q9ULD0	Homo sapiens	40%	97%
Q9VA02	Drosophila melanogaster	36%	100%
Q9ZDY3	Rickettsia prowazekii (strain Madrid E)	33%	100%
V5BIL1	Trypanosoma cruzi	40%	97%
V5BWU3	Trypanosoma cruzi	66%	97%