Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q167_LEIMA

TriTrypDb:

LmjF.36.3510 , LMJLV39_360045300 , LMJSD75_360045200

Length:

186

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q167

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q167

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	83	85	PF00675	0.504
CLV_PCSK_KEX2_1	104	106	PF00082	0.572
CLV_PCSK_KEX2_1	131	133	PF00082	0.456
CLV_PCSK_KEX2_1	43	45	PF00082	0.500
CLV_PCSK_PC1ET2_1	104	106	PF00082	0.572
CLV_PCSK_PC1ET2_1	131	133	PF00082	0.456
CLV_PCSK_PC1ET2_1	43	45	PF00082	0.500
DEG_Nend_Nbox_1	1	3	PF02207	0.681
DOC_MAPK_DCC_7	15	25	PF00069	0.515
DOC_MAPK_gen_1	131	139	PF00069	0.609
DOC_MAPK_MEF2A_6	131	139	PF00069	0.532
DOC_MAPK_NFAT4_5	132	140	PF00069	0.494
DOC_PIKK_1	64	72	PF02985	0.545
DOC_PP2B_LxvP_1	154	157	PF13499	0.694
DOC_PP2B_LxvP_1	160	163	PF13499	0.665
DOC_PP2B_PxIxI_1	33	39	PF00149	0.522
DOC_USP7_MATH_1	121	125	PF00917	0.402
DOC_USP7_MATH_1	14	18	PF00917	0.716
DOC_USP7_MATH_1	145	149	PF00917	0.640
DOC_USP7_UBL2_3	43	47	PF12436	0.562
LIG_14-3-3_CanoR_1	132	136	PF00244	0.500
LIG_14-3-3_CanoR_1	50	56	PF00244	0.556
LIG_14-3-3_CanoR_1	94	100	PF00244	0.686
LIG_Actin_WH2_2	122	138	PF00022	0.489
LIG_EVH1_1	160	164	PF00568	0.646
LIG_FHA_1	25	31	PF00498	0.626
LIG_FHA_1	50	56	PF00498	0.588
LIG_FHA_1	88	94	PF00498	0.603
LIG_FHA_2	27	33	PF00498	0.635
LIG_LIR_Nem_3	116	122	PF02991	0.566
LIG_PCNA_yPIPBox_3	105	119	PF02747	0.522
LIG_SH2_SRC	75	78	PF00017	0.478
LIG_SH2_STAT5	128	131	PF00017	0.366
LIG_SH2_STAT5	75	78	PF00017	0.542
LIG_SH3_1	158	164	PF00018	0.651
LIG_SH3_3	149	155	PF00018	0.717
LIG_SH3_3	156	162	PF00018	0.721
LIG_SUMO_SIM_par_1	26	33	PF11976	0.605
LIG_SUMO_SIM_par_1	75	82	PF11976	0.476
MOD_CK1_1	3	9	PF00069	0.658
MOD_CK1_1	78	84	PF00069	0.480
MOD_CK1_1	95	101	PF00069	0.546
MOD_CK2_1	26	32	PF00069	0.614
MOD_Cter_Amidation	102	105	PF01082	0.594
MOD_GlcNHglycan	114	118	PF01048	0.579
MOD_GlcNHglycan	16	19	PF01048	0.639
MOD_GlcNHglycan	172	175	PF01048	0.556
MOD_GSK3_1	166	173	PF00069	0.642
MOD_NEK2_1	1	6	PF00069	0.685
MOD_NEK2_1	39	44	PF00069	0.565
MOD_PIKK_1	176	182	PF00454	0.652
MOD_PKA_1	131	137	PF00069	0.495
MOD_PKA_2	131	137	PF00069	0.495
MOD_PKA_2	49	55	PF00069	0.546
MOD_PKA_2	95	101	PF00069	0.633
MOD_Plk_1	113	119	PF00069	0.606
MOD_Plk_2-3	87	93	PF00069	0.635
MOD_Plk_4	95	101	PF00069	0.633
TRG_DiLeu_BaEn_4	64	70	PF01217	0.546
TRG_ER_diArg_1	93	96	PF00400	0.491

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0P3J1	Trypanosomatidae	38%	100%
A0A3S7XB75	Leishmania donovani	94%	98%
A4HPL8	Leishmania braziliensis	68%	100%
A4ID46	Leishmania infantum	94%	98%
E9ATD0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%