Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q152_LEIMA

TriTrypDb:

LmjF.36.3653 , LMJLV39_360047000 , LMJSD75_360046700

Length:

197

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q152

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q152

PDB structure(s): 7aih_Z , 7am2_Z , 7ane_Z

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	161	163	PF00675	0.525
CLV_NRD_NRD_1	8	10	PF00675	0.540
CLV_NRD_NRD_1	80	82	PF00675	0.591
CLV_PCSK_KEX2_1	191	193	PF00082	0.486
CLV_PCSK_KEX2_1	8	10	PF00082	0.563
CLV_PCSK_KEX2_1	80	82	PF00082	0.522
CLV_PCSK_PC1ET2_1	191	193	PF00082	0.495
CLV_PCSK_PC7_1	76	82	PF00082	0.506
CLV_PCSK_SKI1_1	191	195	PF00082	0.466
CLV_PCSK_SKI1_1	41	45	PF00082	0.674
CLV_PCSK_SKI1_1	9	13	PF00082	0.692
CLV_Separin_Metazoa	85	89	PF03568	0.552
DEG_Nend_Nbox_1	1	3	PF02207	0.597
DEG_SPOP_SBC_1	176	180	PF00917	0.616
DOC_CYCLIN_yClb1_LxF_4	102	107	PF00134	0.554
DOC_MAPK_gen_1	150	159	PF00069	0.506
DOC_MAPK_MEF2A_6	150	159	PF00069	0.507
DOC_PP1_RVXF_1	102	108	PF00149	0.465
DOC_PP1_RVXF_1	189	196	PF00149	0.469
DOC_PP1_RVXF_1	6	13	PF00149	0.461
DOC_PP4_FxxP_1	142	145	PF00568	0.508
DOC_PP4_FxxP_1	21	24	PF00568	0.504
DOC_USP7_MATH_1	113	117	PF00917	0.457
DOC_USP7_MATH_1	177	181	PF00917	0.671
DOC_USP7_UBL2_3	100	104	PF12436	0.456
DOC_USP7_UBL2_3	150	154	PF12436	0.573
DOC_USP7_UBL2_3	187	191	PF12436	0.520
DOC_WW_Pin1_4	25	30	PF00397	0.494
LIG_deltaCOP1_diTrp_1	46	52	PF00928	0.512
LIG_FHA_1	38	44	PF00498	0.651
LIG_FHA_1	67	73	PF00498	0.519
LIG_FHA_2	26	32	PF00498	0.510
LIG_HP1_1	155	159	PF01393	0.500
LIG_LIR_Apic_2	141	145	PF02991	0.616
LIG_LIR_Nem_3	151	156	PF02991	0.677
LIG_PCNA_yPIPBox_3	88	98	PF02747	0.544
LIG_Pex14_2	21	25	PF04695	0.530
LIG_REV1ctd_RIR_1	192	197	PF16727	0.541
LIG_SH2_PTP2	156	159	PF00017	0.496
LIG_SH2_STAT5	106	109	PF00017	0.464
LIG_SH2_STAT5	120	123	PF00017	0.424
LIG_SH2_STAT5	156	159	PF00017	0.496
LIG_SH3_3	109	115	PF00018	0.469
LIG_SH3_3	130	136	PF00018	0.506
LIG_SH3_4	187	194	PF00018	0.501
LIG_SxIP_EBH_1	79	88	PF03271	0.573
LIG_TRAF2_1	158	161	PF00917	0.525
LIG_UBA3_1	164	172	PF00899	0.713
LIG_UBA3_1	189	197	PF00899	0.584
LIG_WRPW_2	153	156	PF00400	0.516
MOD_CK1_1	175	181	PF00069	0.632
MOD_CK1_1	183	189	PF00069	0.608
MOD_CMANNOS	49	52	PF00535	0.432
MOD_GlcNHglycan	100	103	PF01048	0.461
MOD_GlcNHglycan	173	177	PF01048	0.731
MOD_GlcNHglycan	179	182	PF01048	0.686
MOD_GSK3_1	168	175	PF00069	0.668
MOD_GSK3_1	176	183	PF00069	0.692
MOD_GSK3_1	66	73	PF00069	0.497
MOD_N-GLC_1	66	71	PF02516	0.546
MOD_NEK2_1	2	7	PF00069	0.581
MOD_NEK2_1	37	42	PF00069	0.623
MOD_NEK2_1	66	71	PF00069	0.495
MOD_Plk_1	148	154	PF00069	0.679
MOD_Plk_4	14	20	PF00069	0.547
MOD_ProDKin_1	25	31	PF00069	0.489
MOD_SUMO_rev_2	180	189	PF00179	0.674
TRG_ENDOCYTIC_2	156	159	PF00928	0.490
TRG_ER_diArg_1	34	37	PF00400	0.666
TRG_ER_diArg_1	7	9	PF00400	0.566
TRG_ER_diArg_1	79	81	PF00400	0.584
TRG_NES_CRM1_1	85	95	PF08389	0.547

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4T5	Leptomonas seymouri	84%	99%
A0A0S4J3L6	Bodo saltans	67%	96%
A0A1X0P3A9	Trypanosomatidae	72%	100%
A0A3Q8IP77	Leishmania donovani	95%	99%
A0A422MY87	Trypanosoma rangeli	68%	97%
A4ID33	Leishmania infantum	94%	99%
D0A8I6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	72%	100%
E9AIX9	Leishmania braziliensis	92%	99%
E9ATE5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%