CobW C-terminal domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q145_LEIMA

TriTrypDb:

LmjF.36.3700 , LMJLV39_360047700 , LMJSD75_360047400

Length:

194


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0110165	cellular anatomical entity	1	2

Q4Q145

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q145


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	14	16	PF00675	0.669
CLV_PCSK_SKI1_1	121	125	PF00082	0.524
CLV_PCSK_SKI1_1	38	42	PF00082	0.399
CLV_PCSK_SKI1_1	77	81	PF00082	0.558
DEG_Nend_Nbox_1	1	3	PF02207	0.676
DOC_USP7_MATH_1	39	43	PF00917	0.489
DOC_USP7_MATH_1	7	11	PF00917	0.628
DOC_WW_Pin1_4	128	133	PF00397	0.378
DOC_WW_Pin1_4	26	31	PF00397	0.621
LIG_14-3-3_CanoR_1	38	47	PF00244	0.531
LIG_14-3-3_CanoR_1	9	14	PF00244	0.634
LIG_Clathr_ClatBox_1	19	23	PF01394	0.595
LIG_DCNL_PONY_1	1	4	PF03556	0.629
LIG_EVH1_1	184	188	PF00568	0.561
LIG_FHA_1	169	175	PF00498	0.454
LIG_FHA_2	41	47	PF00498	0.540
LIG_LIR_Gen_1	122	132	PF02991	0.484
LIG_LIR_Gen_1	46	56	PF02991	0.477
LIG_LIR_Nem_3	122	127	PF02991	0.423
LIG_LIR_Nem_3	46	52	PF02991	0.494
LIG_SH2_STAP1	190	194	PF00017	0.677
LIG_SH2_STAT5	154	157	PF00017	0.439
LIG_SH2_STAT5	34	37	PF00017	0.461
LIG_SH3_3	182	188	PF00018	0.551
LIG_UBA3_1	19	27	PF00899	0.598
LIG_WW_1	187	190	PF00397	0.692
MOD_CK1_1	178	184	PF00069	0.573
MOD_CK1_1	26	32	PF00069	0.620
MOD_CK1_1	71	77	PF00069	0.550
MOD_CK2_1	128	134	PF00069	0.543
MOD_GlcNHglycan	180	183	PF01048	0.500
MOD_GlcNHglycan	9	12	PF01048	0.632
MOD_GlcNHglycan	90	93	PF01048	0.450
MOD_GSK3_1	164	171	PF00069	0.503
MOD_GSK3_1	22	29	PF00069	0.621
MOD_N-GLC_1	188	193	PF02516	0.684
MOD_NEK2_1	114	119	PF00069	0.561
MOD_OFUCOSY	51	58	PF10250	0.351
MOD_PK_1	9	15	PF00069	0.670
MOD_Plk_1	107	113	PF00069	0.521
MOD_Plk_1	114	120	PF00069	0.468
MOD_Plk_4	169	175	PF00069	0.486
MOD_ProDKin_1	128	134	PF00069	0.378
MOD_ProDKin_1	26	32	PF00069	0.620
TRG_ENDOCYTIC_2	82	85	PF00928	0.535
TRG_ER_diArg_1	84	87	PF00400	0.535
TRG_Pf-PMV_PEXEL_1	77	81	PF00026	0.592


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I521	Leptomonas seymouri	66%	100%
A0A1X0P3D7	Trypanosomatidae	32%	91%
A0A3R7NA14	Trypanosoma rangeli	29%	87%
A0A3S7XBG2	Leishmania donovani	97%	100%
A4HPN8	Leishmania braziliensis	88%	100%
A4ID26	Leishmania infantum	97%	100%
D0A8H6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	100%
E9ATF2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
V5DA81	Trypanosoma cruzi	32%	71%