NMT1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q125_LEIMA

TriTrypDb:

LmjF.36.3900 , LMJLV39_360049700 , LMJSD75_360049500

Length:

275

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q125

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q125

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	102	104	PF00675	0.659
CLV_PCSK_SKI1_1	223	227	PF00082	0.661
CLV_PCSK_SKI1_1	37	41	PF00082	0.614
DEG_Nend_Nbox_1	1	3	PF02207	0.652
DOC_CYCLIN_yCln2_LP_2	107	113	PF00134	0.636
DOC_MAPK_gen_1	166	175	PF00069	0.649
DOC_MAPK_gen_1	264	272	PF00069	0.603
DOC_MAPK_gen_1	34	43	PF00069	0.689
DOC_MAPK_MEF2A_6	37	45	PF00069	0.596
DOC_PP4_FxxP_1	45	48	PF00568	0.583
DOC_SPAK_OSR1_1	166	170	PF12202	0.672
DOC_USP7_MATH_1	130	134	PF00917	0.720
DOC_USP7_MATH_1	137	141	PF00917	0.723
DOC_USP7_MATH_1	150	154	PF00917	0.541
DOC_USP7_MATH_2	253	259	PF00917	0.644
DOC_WW_Pin1_4	139	144	PF00397	0.735
DOC_WW_Pin1_4	192	197	PF00397	0.747
LIG_14-3-3_CanoR_1	37	42	PF00244	0.567
LIG_APCC_ABBA_1	64	69	PF00400	0.652
LIG_BRCT_BRCA1_1	171	175	PF00533	0.605
LIG_CaM_NSCaTE_8	95	102	PF13499	0.741
LIG_FHA_1	38	44	PF00498	0.557
LIG_FHA_1	85	91	PF00498	0.606
LIG_FHA_2	118	124	PF00498	0.624
LIG_FHA_2	150	156	PF00498	0.750
LIG_LIR_Apic_2	42	48	PF02991	0.583
LIG_LIR_Gen_1	268	274	PF02991	0.666
LIG_LIR_Gen_1	46	55	PF02991	0.592
LIG_LIR_Nem_3	13	19	PF02991	0.571
LIG_LIR_Nem_3	165	170	PF02991	0.666
LIG_LIR_Nem_3	268	272	PF02991	0.658
LIG_LIR_Nem_3	46	52	PF02991	0.605
LIG_MYND_1	160	164	PF01753	0.618
LIG_NRBOX	172	178	PF00104	0.696
LIG_Pex14_2	45	49	PF04695	0.546
LIG_PTB_Apo_2	202	209	PF02174	0.697
LIG_SH2_SRC	55	58	PF00017	0.702
LIG_SH2_STAP1	11	15	PF00017	0.587
LIG_SH2_STAP1	16	20	PF00017	0.557
LIG_SH2_STAP1	55	59	PF00017	0.626
LIG_SH2_STAT5	19	22	PF00017	0.575
LIG_SH2_STAT5	269	272	PF00017	0.647
LIG_SH3_3	107	113	PF00018	0.738
LIG_SUMO_SIM_anti_2	40	46	PF11976	0.580
LIG_SUMO_SIM_par_1	86	91	PF11976	0.640
LIG_TRAF2_1	54	57	PF00917	0.595
LIG_TYR_ITIM	65	70	PF00017	0.765
MOD_CK1_1	149	155	PF00069	0.770
MOD_CK1_1	84	90	PF00069	0.658
MOD_CK2_1	117	123	PF00069	0.663
MOD_CK2_1	149	155	PF00069	0.749
MOD_CK2_1	50	56	PF00069	0.630
MOD_GlcNHglycan	132	135	PF01048	0.699
MOD_GlcNHglycan	148	151	PF01048	0.696
MOD_GlcNHglycan	196	199	PF01048	0.835
MOD_GlcNHglycan	272	275	PF01048	0.656
MOD_GlcNHglycan	51	55	PF01048	0.684
MOD_GlcNHglycan	83	86	PF01048	0.684
MOD_GSK3_1	146	153	PF00069	0.733
MOD_GSK3_1	158	165	PF00069	0.635
MOD_GSK3_1	18	25	PF00069	0.599
MOD_GSK3_1	84	91	PF00069	0.651
MOD_NEK2_1	117	122	PF00069	0.739
MOD_NEK2_1	138	143	PF00069	0.703
MOD_NEK2_1	177	182	PF00069	0.629
MOD_NEK2_1	186	191	PF00069	0.651
MOD_NEK2_1	23	28	PF00069	0.706
MOD_NEK2_1	88	93	PF00069	0.630
MOD_Plk_1	187	193	PF00069	0.729
MOD_Plk_1	50	56	PF00069	0.630
MOD_Plk_4	238	244	PF00069	0.747
MOD_Plk_4	255	261	PF00069	0.496
MOD_ProDKin_1	139	145	PF00069	0.738
MOD_ProDKin_1	192	198	PF00069	0.747
TRG_ENDOCYTIC_2	269	272	PF00928	0.647
TRG_ENDOCYTIC_2	67	70	PF00928	0.770

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6L2	Leptomonas seymouri	43%	100%
A0A3Q8IL86	Leishmania donovani	90%	100%
A4HPQ7	Leishmania braziliensis	74%	100%
A4ID06	Leishmania infantum	90%	100%
E9ATH2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%