LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania major
UniProt:
Q4Q119_LEIMA
TriTrypDb:
LmjF.36.3960 , LMJLV39_360050300 , LMJSD75_360050100 *
Length:
1017

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q119
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q119

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 272 276 PF00656 0.509
CLV_C14_Caspase3-7 322 326 PF00656 0.722
CLV_C14_Caspase3-7 669 673 PF00656 0.587
CLV_C14_Caspase3-7 980 984 PF00656 0.692
CLV_NRD_NRD_1 1004 1006 PF00675 0.758
CLV_NRD_NRD_1 357 359 PF00675 0.743
CLV_NRD_NRD_1 370 372 PF00675 0.587
CLV_NRD_NRD_1 510 512 PF00675 0.706
CLV_NRD_NRD_1 540 542 PF00675 0.653
CLV_NRD_NRD_1 62 64 PF00675 0.675
CLV_PCSK_FUR_1 229 233 PF00082 0.609
CLV_PCSK_FUR_1 538 542 PF00082 0.655
CLV_PCSK_KEX2_1 1004 1006 PF00082 0.758
CLV_PCSK_KEX2_1 231 233 PF00082 0.614
CLV_PCSK_KEX2_1 357 359 PF00082 0.656
CLV_PCSK_KEX2_1 361 363 PF00082 0.612
CLV_PCSK_KEX2_1 370 372 PF00082 0.610
CLV_PCSK_KEX2_1 510 512 PF00082 0.683
CLV_PCSK_KEX2_1 522 524 PF00082 0.775
CLV_PCSK_KEX2_1 540 542 PF00082 0.628
CLV_PCSK_KEX2_1 892 894 PF00082 0.583
CLV_PCSK_PC1ET2_1 231 233 PF00082 0.614
CLV_PCSK_PC1ET2_1 361 363 PF00082 0.641
CLV_PCSK_PC1ET2_1 522 524 PF00082 0.773
CLV_PCSK_PC1ET2_1 892 894 PF00082 0.583
CLV_PCSK_PC7_1 1000 1006 PF00082 0.736
CLV_PCSK_PC7_1 357 363 PF00082 0.632
CLV_PCSK_PC7_1 366 372 PF00082 0.669
CLV_PCSK_SKI1_1 577 581 PF00082 0.681
CLV_PCSK_SKI1_1 771 775 PF00082 0.695
CLV_PCSK_SKI1_1 797 801 PF00082 0.623
CLV_PCSK_SKI1_1 831 835 PF00082 0.562
DEG_COP1_1 382 393 PF00400 0.653
DEG_SCF_FBW7_1 414 421 PF00400 0.584
DEG_SCF_FBW7_1 453 460 PF00400 0.722
DEG_SPOP_SBC_1 149 153 PF00917 0.668
DEG_SPOP_SBC_1 526 530 PF00917 0.682
DOC_CKS1_1 21 26 PF01111 0.714
DOC_CKS1_1 415 420 PF01111 0.586
DOC_CYCLIN_RxL_1 794 803 PF00134 0.622
DOC_MAPK_HePTP_8 245 257 PF00069 0.620
DOC_MAPK_MEF2A_6 142 150 PF00069 0.551
DOC_MAPK_MEF2A_6 248 257 PF00069 0.694
DOC_PP2B_LxvP_1 137 140 PF13499 0.742
DOC_PP2B_LxvP_1 146 149 PF13499 0.581
DOC_PP2B_LxvP_1 569 572 PF13499 0.707
DOC_PP4_FxxP_1 532 535 PF00568 0.781
DOC_PP4_FxxP_1 581 584 PF00568 0.617
DOC_USP7_MATH_1 131 135 PF00917 0.803
DOC_USP7_MATH_1 149 153 PF00917 0.663
DOC_USP7_MATH_1 184 188 PF00917 0.737
DOC_USP7_MATH_1 376 380 PF00917 0.653
DOC_USP7_MATH_1 39 43 PF00917 0.641
DOC_USP7_MATH_1 418 422 PF00917 0.776
DOC_USP7_MATH_1 458 462 PF00917 0.665
DOC_USP7_MATH_1 512 516 PF00917 0.637
DOC_USP7_MATH_1 526 530 PF00917 0.699
DOC_USP7_MATH_1 565 569 PF00917 0.710
DOC_USP7_MATH_1 723 727 PF00917 0.686
DOC_USP7_MATH_1 96 100 PF00917 0.769
DOC_USP7_MATH_1 962 966 PF00917 0.766
DOC_USP7_MATH_1 982 986 PF00917 0.627
DOC_USP7_UBL2_3 518 522 PF12436 0.581
DOC_WW_Pin1_4 141 146 PF00397 0.734
DOC_WW_Pin1_4 156 161 PF00397 0.541
DOC_WW_Pin1_4 20 25 PF00397 0.784
DOC_WW_Pin1_4 281 286 PF00397 0.525
DOC_WW_Pin1_4 334 339 PF00397 0.663
DOC_WW_Pin1_4 344 349 PF00397 0.644
DOC_WW_Pin1_4 364 369 PF00397 0.642
DOC_WW_Pin1_4 414 419 PF00397 0.577
DOC_WW_Pin1_4 424 429 PF00397 0.855
DOC_WW_Pin1_4 453 458 PF00397 0.688
DOC_WW_Pin1_4 522 527 PF00397 0.664
DOC_WW_Pin1_4 531 536 PF00397 0.728
DOC_WW_Pin1_4 567 572 PF00397 0.674
DOC_WW_Pin1_4 590 595 PF00397 0.783
DOC_WW_Pin1_4 858 863 PF00397 0.641
DOC_WW_Pin1_4 868 873 PF00397 0.660
DOC_WW_Pin1_4 924 929 PF00397 0.833
LIG_14-3-3_CanoR_1 154 162 PF00244 0.679
LIG_14-3-3_CanoR_1 206 210 PF00244 0.645
LIG_14-3-3_CanoR_1 232 236 PF00244 0.612
LIG_14-3-3_CanoR_1 333 338 PF00244 0.600
LIG_14-3-3_CanoR_1 370 378 PF00244 0.759
LIG_14-3-3_CanoR_1 470 479 PF00244 0.571
LIG_14-3-3_CanoR_1 511 521 PF00244 0.698
LIG_14-3-3_CanoR_1 538 544 PF00244 0.736
LIG_14-3-3_CanoR_1 577 582 PF00244 0.681
LIG_14-3-3_CanoR_1 63 73 PF00244 0.664
LIG_14-3-3_CanoR_1 655 665 PF00244 0.686
LIG_14-3-3_CanoR_1 699 706 PF00244 0.541
LIG_14-3-3_CanoR_1 7 11 PF00244 0.640
LIG_14-3-3_CanoR_1 709 713 PF00244 0.540
LIG_14-3-3_CanoR_1 831 840 PF00244 0.730
LIG_Actin_WH2_2 562 579 PF00022 0.700
LIG_Actin_WH2_2 896 912 PF00022 0.525
LIG_BIR_III_4 983 987 PF00653 0.738
LIG_BRCT_BRCA1_1 528 532 PF00533 0.787
LIG_BRCT_BRCA1_1 642 646 PF00533 0.539
LIG_CtBP_PxDLS_1 436 440 PF00389 0.714
LIG_FHA_1 103 109 PF00498 0.602
LIG_FHA_1 194 200 PF00498 0.588
LIG_FHA_1 240 246 PF00498 0.532
LIG_FHA_1 290 296 PF00498 0.462
LIG_FHA_1 297 303 PF00498 0.508
LIG_FHA_1 32 38 PF00498 0.729
LIG_FHA_1 373 379 PF00498 0.777
LIG_FHA_1 380 386 PF00498 0.534
LIG_FHA_1 467 473 PF00498 0.810
LIG_FHA_1 580 586 PF00498 0.696
LIG_FHA_1 637 643 PF00498 0.494
LIG_FHA_1 661 667 PF00498 0.676
LIG_FHA_1 683 689 PF00498 0.721
LIG_FHA_1 906 912 PF00498 0.627
LIG_FHA_2 712 718 PF00498 0.686
LIG_FHA_2 770 776 PF00498 0.704
LIG_FHA_2 813 819 PF00498 0.686
LIG_FHA_2 978 984 PF00498 0.720
LIG_FHA_2 989 995 PF00498 0.567
LIG_HCF-1_HBM_1 848 851 PF13415 0.743
LIG_Integrin_RGD_1 730 732 PF01839 0.575
LIG_LIR_Apic_2 412 418 PF02991 0.647
LIG_LIR_Apic_2 529 535 PF02991 0.783
LIG_LIR_Apic_2 578 584 PF02991 0.751
LIG_LIR_Apic_2 927 933 PF02991 0.592
LIG_LIR_Gen_1 643 652 PF02991 0.559
LIG_LIR_Gen_1 710 720 PF02991 0.522
LIG_LIR_Nem_3 885 891 PF02991 0.591
LIG_MYND_1 344 348 PF01753 0.686
LIG_MYND_1 73 77 PF01753 0.583
LIG_SH2_CRK 415 419 PF00017 0.649
LIG_SH2_CRK 930 934 PF00017 0.599
LIG_SH2_STAT5 832 835 PF00017 0.754
LIG_SH2_STAT5 857 860 PF00017 0.680
LIG_SH2_STAT5 995 998 PF00017 0.594
LIG_SH3_1 789 795 PF00018 0.697
LIG_SH3_2 428 433 PF14604 0.683
LIG_SH3_2 792 797 PF14604 0.639
LIG_SH3_3 210 216 PF00018 0.686
LIG_SH3_3 332 338 PF00018 0.842
LIG_SH3_3 425 431 PF00018 0.645
LIG_SH3_3 489 495 PF00018 0.678
LIG_SH3_3 74 80 PF00018 0.650
LIG_SH3_3 789 795 PF00018 0.643
LIG_SH3_3 970 976 PF00018 0.788
LIG_SUMO_SIM_anti_2 449 456 PF11976 0.587
LIG_TRAF2_1 320 323 PF00917 0.787
LIG_TRAF2_1 461 464 PF00917 0.724
LIG_TRAF2_1 600 603 PF00917 0.752
LIG_TRAF2_1 743 746 PF00917 0.567
LIG_WW_3 456 460 PF00397 0.633
LIG_WW_3 794 798 PF00397 0.630
MOD_CDC14_SPxK_1 367 370 PF00782 0.723
MOD_CDK_SPxK_1 364 370 PF00069 0.720
MOD_CDK_SPxK_1 453 459 PF00069 0.720
MOD_CDK_SPxK_1 868 874 PF00069 0.764
MOD_CDK_SPxxK_3 156 163 PF00069 0.557
MOD_CDK_SPxxK_3 364 371 PF00069 0.625
MOD_CDK_SPxxK_3 531 538 PF00069 0.716
MOD_CDK_SPxxK_3 924 931 PF00069 0.681
MOD_CK1_1 123 129 PF00069 0.683
MOD_CK1_1 14 20 PF00069 0.782
MOD_CK1_1 153 159 PF00069 0.715
MOD_CK1_1 271 277 PF00069 0.585
MOD_CK1_1 306 312 PF00069 0.692
MOD_CK1_1 334 340 PF00069 0.796
MOD_CK1_1 374 380 PF00069 0.660
MOD_CK1_1 386 392 PF00069 0.722
MOD_CK1_1 422 428 PF00069 0.673
MOD_CK1_1 473 479 PF00069 0.726
MOD_CK1_1 506 512 PF00069 0.777
MOD_CK1_1 525 531 PF00069 0.521
MOD_CK1_1 556 562 PF00069 0.700
MOD_CK1_1 608 614 PF00069 0.612
MOD_CK1_1 628 634 PF00069 0.710
MOD_CK1_1 67 73 PF00069 0.784
MOD_CK1_1 677 683 PF00069 0.756
MOD_CK1_1 711 717 PF00069 0.680
MOD_CK1_1 861 867 PF00069 0.711
MOD_CK1_1 966 972 PF00069 0.741
MOD_CK1_1 99 105 PF00069 0.752
MOD_CK2_1 113 119 PF00069 0.604
MOD_CK2_1 231 237 PF00069 0.488
MOD_CK2_1 323 329 PF00069 0.722
MOD_CK2_1 344 350 PF00069 0.695
MOD_CK2_1 389 395 PF00069 0.769
MOD_CK2_1 458 464 PF00069 0.781
MOD_CK2_1 711 717 PF00069 0.553
MOD_CK2_1 741 747 PF00069 0.714
MOD_CK2_1 812 818 PF00069 0.604
MOD_CK2_1 934 940 PF00069 0.766
MOD_DYRK1A_RPxSP_1 364 368 PF00069 0.649
MOD_GlcNHglycan 110 113 PF01048 0.602
MOD_GlcNHglycan 122 125 PF01048 0.718
MOD_GlcNHglycan 133 136 PF01048 0.634
MOD_GlcNHglycan 156 159 PF01048 0.610
MOD_GlcNHglycan 16 19 PF01048 0.784
MOD_GlcNHglycan 310 313 PF01048 0.725
MOD_GlcNHglycan 395 399 PF01048 0.689
MOD_GlcNHglycan 43 46 PF01048 0.609
MOD_GlcNHglycan 472 475 PF01048 0.766
MOD_GlcNHglycan 514 517 PF01048 0.618
MOD_GlcNHglycan 555 558 PF01048 0.692
MOD_GlcNHglycan 590 593 PF01048 0.746
MOD_GlcNHglycan 623 626 PF01048 0.623
MOD_GlcNHglycan 656 659 PF01048 0.614
MOD_GlcNHglycan 66 69 PF01048 0.727
MOD_GlcNHglycan 680 683 PF01048 0.674
MOD_GlcNHglycan 690 693 PF01048 0.707
MOD_GlcNHglycan 725 728 PF01048 0.581
MOD_GlcNHglycan 802 805 PF01048 0.606
MOD_GlcNHglycan 81 84 PF01048 0.823
MOD_GlcNHglycan 840 843 PF01048 0.732
MOD_GlcNHglycan 922 925 PF01048 0.766
MOD_GlcNHglycan 935 939 PF01048 0.605
MOD_GlcNHglycan 983 987 PF01048 0.735
MOD_GSK3_1 149 156 PF00069 0.630
MOD_GSK3_1 173 180 PF00069 0.647
MOD_GSK3_1 253 260 PF00069 0.485
MOD_GSK3_1 301 308 PF00069 0.608
MOD_GSK3_1 372 379 PF00069 0.671
MOD_GSK3_1 405 412 PF00069 0.763
MOD_GSK3_1 414 421 PF00069 0.628
MOD_GSK3_1 448 455 PF00069 0.762
MOD_GSK3_1 466 473 PF00069 0.812
MOD_GSK3_1 499 506 PF00069 0.650
MOD_GSK3_1 522 529 PF00069 0.710
MOD_GSK3_1 575 582 PF00069 0.660
MOD_GSK3_1 621 628 PF00069 0.711
MOD_GSK3_1 63 70 PF00069 0.774
MOD_GSK3_1 636 643 PF00069 0.485
MOD_GSK3_1 656 663 PF00069 0.675
MOD_GSK3_1 673 680 PF00069 0.785
MOD_GSK3_1 682 689 PF00069 0.673
MOD_GSK3_1 707 714 PF00069 0.545
MOD_GSK3_1 765 772 PF00069 0.726
MOD_GSK3_1 849 856 PF00069 0.629
MOD_GSK3_1 861 868 PF00069 0.668
MOD_GSK3_1 920 927 PF00069 0.710
MOD_GSK3_1 96 103 PF00069 0.722
MOD_GSK3_1 962 969 PF00069 0.836
MOD_N-GLC_1 14 19 PF02516 0.652
MOD_N-GLC_1 281 286 PF02516 0.507
MOD_N-GLC_1 419 424 PF02516 0.779
MOD_N-GLC_1 963 968 PF02516 0.622
MOD_N-GLC_2 4 6 PF02516 0.693
MOD_NEK2_1 150 155 PF00069 0.737
MOD_NEK2_1 185 190 PF00069 0.678
MOD_NEK2_1 289 294 PF00069 0.492
MOD_NEK2_1 305 310 PF00069 0.688
MOD_NEK2_1 452 457 PF00069 0.820
MOD_NEK2_1 587 592 PF00069 0.718
MOD_NEK2_1 636 641 PF00069 0.544
MOD_NEK2_1 688 693 PF00069 0.760
MOD_NEK2_1 716 721 PF00069 0.563
MOD_NEK2_2 6 11 PF00069 0.581
MOD_NEK2_2 905 910 PF00069 0.555
MOD_PIKK_1 113 119 PF00454 0.604
MOD_PIKK_1 17 23 PF00454 0.759
MOD_PIKK_1 262 268 PF00454 0.481
MOD_PIKK_1 409 415 PF00454 0.787
MOD_PIKK_1 660 666 PF00454 0.700
MOD_PIKK_1 698 704 PF00454 0.532
MOD_PIKK_1 966 972 PF00454 0.722
MOD_PK_1 231 237 PF00069 0.565
MOD_PKA_1 231 237 PF00069 0.565
MOD_PKA_1 409 415 PF00069 0.787
MOD_PKA_1 63 69 PF00069 0.707
MOD_PKA_2 153 159 PF00069 0.673
MOD_PKA_2 205 211 PF00069 0.669
MOD_PKA_2 231 237 PF00069 0.565
MOD_PKA_2 253 259 PF00069 0.513
MOD_PKA_2 369 375 PF00069 0.745
MOD_PKA_2 379 385 PF00069 0.523
MOD_PKA_2 458 464 PF00069 0.742
MOD_PKA_2 539 545 PF00069 0.728
MOD_PKA_2 6 12 PF00069 0.637
MOD_PKA_2 62 68 PF00069 0.703
MOD_PKA_2 654 660 PF00069 0.567
MOD_PKA_2 698 704 PF00069 0.552
MOD_PKA_2 708 714 PF00069 0.568
MOD_PKA_2 812 818 PF00069 0.604
MOD_PKA_2 853 859 PF00069 0.637
MOD_PKA_2 999 1005 PF00069 0.732
MOD_PKB_1 705 713 PF00069 0.529
MOD_Plk_1 422 428 PF00069 0.791
MOD_Plk_1 448 454 PF00069 0.704
MOD_Plk_1 485 491 PF00069 0.620
MOD_Plk_1 629 635 PF00069 0.546
MOD_Plk_1 707 713 PF00069 0.600
MOD_Plk_1 716 722 PF00069 0.505
MOD_Plk_1 847 853 PF00069 0.626
MOD_Plk_1 99 105 PF00069 0.678
MOD_Plk_2-3 323 329 PF00069 0.630
MOD_Plk_4 284 290 PF00069 0.543
MOD_Plk_4 448 454 PF00069 0.768
MOD_Plk_4 474 480 PF00069 0.661
MOD_Plk_4 486 492 PF00069 0.585
MOD_Plk_4 527 533 PF00069 0.786
MOD_Plk_4 616 622 PF00069 0.728
MOD_Plk_4 708 714 PF00069 0.548
MOD_Plk_4 853 859 PF00069 0.647
MOD_ProDKin_1 141 147 PF00069 0.735
MOD_ProDKin_1 156 162 PF00069 0.542
MOD_ProDKin_1 20 26 PF00069 0.781
MOD_ProDKin_1 281 287 PF00069 0.522
MOD_ProDKin_1 334 340 PF00069 0.662
MOD_ProDKin_1 344 350 PF00069 0.641
MOD_ProDKin_1 364 370 PF00069 0.644
MOD_ProDKin_1 414 420 PF00069 0.579
MOD_ProDKin_1 424 430 PF00069 0.846
MOD_ProDKin_1 453 459 PF00069 0.691
MOD_ProDKin_1 522 528 PF00069 0.665
MOD_ProDKin_1 531 537 PF00069 0.727
MOD_ProDKin_1 567 573 PF00069 0.674
MOD_ProDKin_1 590 596 PF00069 0.782
MOD_ProDKin_1 858 864 PF00069 0.639
MOD_ProDKin_1 868 874 PF00069 0.663
MOD_ProDKin_1 924 930 PF00069 0.835
MOD_SUMO_for_1 521 524 PF00179 0.587
MOD_SUMO_rev_2 952 962 PF00179 0.661
TRG_DiLeu_BaEn_1 486 491 PF01217 0.623
TRG_DiLeu_BaLyEn_6 341 346 PF01217 0.705
TRG_DiLeu_BaLyEn_6 871 876 PF01217 0.710
TRG_ENDOCYTIC_2 891 894 PF00928 0.587
TRG_ER_diArg_1 1003 1005 PF00400 0.645
TRG_ER_diArg_1 369 371 PF00400 0.641
TRG_ER_diArg_1 537 540 PF00400 0.661
TRG_ER_diArg_1 55 58 PF00400 0.641
TRG_ER_diArg_1 652 655 PF00400 0.620
TRG_ER_diArg_1 997 1000 PF00400 0.690
TRG_NLS_MonoExtN_4 358 365 PF00514 0.728
TRG_Pf-PMV_PEXEL_1 874 879 PF00026 0.771

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PEK5 Leptomonas seymouri 33% 100%
A0A3Q8IIW4 Leishmania donovani 88% 100%
A4HPR4 Leishmania braziliensis 67% 100%
A4ID00 Leishmania infantum 88% 100%
E9ATH8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 85% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS