LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q0Z8_LEIMA
TriTrypDb:
LmjF.36.4160 , LMJLV39_360052700 * , LMJSD75_360052600 *
Length:
329

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q0Z8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q0Z8

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 131 133 PF00675 0.600
CLV_NRD_NRD_1 135 137 PF00675 0.599
CLV_NRD_NRD_1 20 22 PF00675 0.661
CLV_NRD_NRD_1 301 303 PF00675 0.683
CLV_PCSK_KEX2_1 109 111 PF00082 0.616
CLV_PCSK_KEX2_1 135 137 PF00082 0.607
CLV_PCSK_KEX2_1 20 22 PF00082 0.552
CLV_PCSK_KEX2_1 301 303 PF00082 0.690
CLV_PCSK_KEX2_1 309 311 PF00082 0.624
CLV_PCSK_KEX2_1 5 7 PF00082 0.620
CLV_PCSK_KEX2_1 91 93 PF00082 0.605
CLV_PCSK_PC1ET2_1 109 111 PF00082 0.776
CLV_PCSK_PC1ET2_1 20 22 PF00082 0.552
CLV_PCSK_PC1ET2_1 309 311 PF00082 0.650
CLV_PCSK_PC1ET2_1 5 7 PF00082 0.620
CLV_PCSK_PC1ET2_1 91 93 PF00082 0.605
CLV_PCSK_SKI1_1 211 215 PF00082 0.608
CLV_PCSK_SKI1_1 218 222 PF00082 0.604
CLV_PCSK_SKI1_1 22 26 PF00082 0.554
CLV_PCSK_SKI1_1 8 12 PF00082 0.604
CLV_PCSK_SKI1_1 84 88 PF00082 0.598
DEG_SPOP_SBC_1 197 201 PF00917 0.628
DOC_USP7_MATH_1 197 201 PF00917 0.673
DOC_USP7_MATH_1 205 209 PF00917 0.565
DOC_USP7_MATH_1 72 76 PF00917 0.612
DOC_USP7_MATH_1 86 90 PF00917 0.577
DOC_USP7_UBL2_3 11 15 PF12436 0.607
DOC_USP7_UBL2_3 214 218 PF12436 0.635
DOC_USP7_UBL2_3 87 91 PF12436 0.604
DOC_WW_Pin1_4 33 38 PF00397 0.612
DOC_WW_Pin1_4 42 47 PF00397 0.557
LIG_14-3-3_CanoR_1 104 109 PF00244 0.570
LIG_14-3-3_CanoR_1 21 30 PF00244 0.715
LIG_14-3-3_CanoR_1 255 261 PF00244 0.539
LIG_14-3-3_CanoR_1 301 308 PF00244 0.562
LIG_BIR_II_1 1 5 PF00653 0.774
LIG_BRCT_BRCA1_1 174 178 PF00533 0.469
LIG_FHA_1 114 120 PF00498 0.634
LIG_FHA_1 125 131 PF00498 0.704
LIG_FHA_1 34 40 PF00498 0.646
LIG_FHA_1 74 80 PF00498 0.601
LIG_FHA_2 175 181 PF00498 0.448
LIG_LIR_Nem_3 175 181 PF02991 0.507
LIG_SH2_STAT5 237 240 PF00017 0.636
LIG_SH3_3 230 236 PF00018 0.578
LIG_SH3_3 43 49 PF00018 0.547
LIG_SUMO_SIM_par_1 126 131 PF11976 0.523
LIG_TRAF2_1 276 279 PF00917 0.560
MOD_CDK_SPK_2 33 38 PF00069 0.571
MOD_CK1_1 172 178 PF00069 0.591
MOD_CK1_1 190 196 PF00069 0.588
MOD_CK1_1 199 205 PF00069 0.657
MOD_CK1_1 207 213 PF00069 0.714
MOD_CK1_1 263 269 PF00069 0.599
MOD_CK1_1 271 277 PF00069 0.634
MOD_CK1_1 300 306 PF00069 0.569
MOD_CK1_1 75 81 PF00069 0.568
MOD_CK2_1 174 180 PF00069 0.399
MOD_CK2_1 246 252 PF00069 0.636
MOD_CK2_1 254 260 PF00069 0.653
MOD_CK2_1 263 269 PF00069 0.561
MOD_CK2_1 273 279 PF00069 0.515
MOD_CK2_1 282 288 PF00069 0.621
MOD_CK2_1 300 306 PF00069 0.585
MOD_Cter_Amidation 18 21 PF01082 0.559
MOD_GlcNHglycan 189 192 PF01048 0.576
MOD_GlcNHglycan 238 241 PF01048 0.578
MOD_GlcNHglycan 290 293 PF01048 0.634
MOD_GlcNHglycan 302 305 PF01048 0.588
MOD_GSK3_1 113 120 PF00069 0.587
MOD_GSK3_1 192 199 PF00069 0.672
MOD_GSK3_1 203 210 PF00069 0.580
MOD_GSK3_1 256 263 PF00069 0.624
MOD_GSK3_1 264 271 PF00069 0.653
MOD_GSK3_1 296 303 PF00069 0.739
MOD_GSK3_1 73 80 PF00069 0.640
MOD_N-GLC_1 104 109 PF02516 0.578
MOD_N-GLC_1 124 129 PF02516 0.582
MOD_N-GLC_1 98 103 PF02516 0.629
MOD_NEK2_1 121 126 PF00069 0.546
MOD_NEK2_1 261 266 PF00069 0.529
MOD_NEK2_2 86 91 PF00069 0.625
MOD_PIKK_1 199 205 PF00454 0.612
MOD_PKA_1 22 28 PF00069 0.655
MOD_PKA_2 103 109 PF00069 0.605
MOD_PKA_2 22 28 PF00069 0.647
MOD_PKA_2 254 260 PF00069 0.609
MOD_PKA_2 300 306 PF00069 0.585
MOD_PKA_2 63 69 PF00069 0.608
MOD_PKB_1 21 29 PF00069 0.622
MOD_Plk_1 104 110 PF00069 0.554
MOD_Plk_1 124 130 PF00069 0.590
MOD_Plk_4 162 168 PF00069 0.436
MOD_Plk_4 174 180 PF00069 0.399
MOD_Plk_4 268 274 PF00069 0.593
MOD_ProDKin_1 33 39 PF00069 0.608
MOD_ProDKin_1 42 48 PF00069 0.547
TRG_DiLeu_BaEn_4 150 156 PF01217 0.534
TRG_ER_diArg_1 6 9 PF00400 0.624
TRG_NLS_Bipartite_1 5 25 PF00514 0.672
TRG_NLS_Bipartite_1 91 113 PF00514 0.644
TRG_NLS_MonoCore_2 19 24 PF00514 0.576
TRG_NLS_MonoCore_2 4 9 PF00514 0.561
TRG_NLS_MonoExtN_4 20 25 PF00514 0.618
TRG_NLS_MonoExtN_4 3 9 PF00514 0.557
TRG_Pf-PMV_PEXEL_1 91 95 PF00026 0.688

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P3X1 Leptomonas seymouri 41% 89%
A0A3Q8IIX5 Leishmania donovani 85% 100%
A4HPT5 Leishmania braziliensis 61% 100%
A4IE57 Leishmania infantum 84% 100%
E9ATK0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 82% 99%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS