LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q0V7_LEIMA
TriTrypDb:
LmjF.36.4570 , LMJLV39_360057200 , LMJSD75_360057000
Length:
322

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q0V7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q0V7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 135 139 PF00656 0.419
CLV_C14_Caspase3-7 27 31 PF00656 0.720
CLV_NRD_NRD_1 152 154 PF00675 0.535
CLV_NRD_NRD_1 16 18 PF00675 0.557
CLV_NRD_NRD_1 92 94 PF00675 0.532
CLV_PCSK_KEX2_1 92 94 PF00082 0.491
CLV_PCSK_SKI1_1 210 214 PF00082 0.455
CLV_PCSK_SKI1_1 224 228 PF00082 0.362
CLV_PCSK_SKI1_1 65 69 PF00082 0.356
DEG_APCC_DBOX_1 91 99 PF00400 0.525
DEG_MDM2_SWIB_1 306 313 PF02201 0.363
DOC_ANK_TNKS_1 133 140 PF00023 0.419
DOC_CKS1_1 146 151 PF01111 0.397
DOC_MAPK_gen_1 120 129 PF00069 0.405
DOC_MAPK_gen_1 89 98 PF00069 0.520
DOC_PP1_RVXF_1 59 65 PF00149 0.499
DOC_USP7_MATH_1 140 144 PF00917 0.499
DOC_USP7_MATH_1 186 190 PF00917 0.596
DOC_USP7_MATH_1 259 263 PF00917 0.615
DOC_WW_Pin1_4 145 150 PF00397 0.390
DOC_WW_Pin1_4 182 187 PF00397 0.575
DOC_WW_Pin1_4 43 48 PF00397 0.573
LIG_14-3-3_CanoR_1 210 217 PF00244 0.447
LIG_14-3-3_CanoR_1 219 224 PF00244 0.339
LIG_14-3-3_CanoR_1 278 283 PF00244 0.425
LIG_14-3-3_CanoR_1 32 40 PF00244 0.574
LIG_Actin_WH2_1 120 136 PF00022 0.413
LIG_Actin_WH2_2 121 136 PF00022 0.456
LIG_APCC_ABBA_1 121 126 PF00400 0.383
LIG_APCC_ABBAyCdc20_2 120 126 PF00400 0.364
LIG_BRCT_BRCA1_1 103 107 PF00533 0.429
LIG_FHA_1 160 166 PF00498 0.606
LIG_FHA_1 191 197 PF00498 0.445
LIG_FHA_1 289 295 PF00498 0.563
LIG_FHA_2 14 20 PF00498 0.635
LIG_FHA_2 220 226 PF00498 0.443
LIG_FHA_2 25 31 PF00498 0.643
LIG_GBD_Chelix_1 294 302 PF00786 0.455
LIG_LIR_Gen_1 104 115 PF02991 0.462
LIG_LIR_Gen_1 162 171 PF02991 0.411
LIG_LIR_Gen_1 268 276 PF02991 0.478
LIG_LIR_Gen_1 280 290 PF02991 0.454
LIG_LIR_Gen_1 304 313 PF02991 0.364
LIG_LIR_LC3C_4 125 129 PF02991 0.453
LIG_LIR_Nem_3 104 110 PF02991 0.404
LIG_LIR_Nem_3 155 161 PF02991 0.460
LIG_LIR_Nem_3 162 167 PF02991 0.432
LIG_LIR_Nem_3 268 273 PF02991 0.492
LIG_LIR_Nem_3 280 285 PF02991 0.489
LIG_LIR_Nem_3 304 309 PF02991 0.376
LIG_Pex14_2 306 310 PF04695 0.354
LIG_SH2_CRK 282 286 PF00017 0.488
LIG_SH2_STAT5 221 224 PF00017 0.440
LIG_SH2_STAT5 235 238 PF00017 0.492
LIG_SH3_3 143 149 PF00018 0.524
LIG_SH3_3 17 23 PF00018 0.592
LIG_SH3_3 233 239 PF00018 0.485
LIG_SH3_3 253 259 PF00018 0.538
LIG_TRAF2_1 206 209 PF00917 0.439
LIG_TRAF2_1 57 60 PF00917 0.450
LIG_TRAF2_1 79 82 PF00917 0.440
LIG_TYR_ITSM 278 285 PF00017 0.469
MOD_CDK_SPxK_1 145 151 PF00069 0.395
MOD_CDK_SPxK_1 43 49 PF00069 0.594
MOD_CK1_1 190 196 PF00069 0.439
MOD_CK1_1 24 30 PF00069 0.645
MOD_CK1_1 315 321 PF00069 0.462
MOD_CK1_1 33 39 PF00069 0.657
MOD_CK2_1 186 192 PF00069 0.529
MOD_CK2_1 265 271 PF00069 0.519
MOD_CK2_1 33 39 PF00069 0.699
MOD_CK2_1 54 60 PF00069 0.512
MOD_Cter_Amidation 90 93 PF01082 0.492
MOD_GlcNHglycan 103 106 PF01048 0.497
MOD_GlcNHglycan 142 145 PF01048 0.530
MOD_GlcNHglycan 177 180 PF01048 0.547
MOD_GlcNHglycan 192 196 PF01048 0.519
MOD_GlcNHglycan 22 26 PF01048 0.719
MOD_GlcNHglycan 273 276 PF01048 0.419
MOD_GlcNHglycan 317 320 PF01048 0.449
MOD_GlcNHglycan 32 35 PF01048 0.574
MOD_GlcNHglycan 9 12 PF01048 0.562
MOD_GSK3_1 182 189 PF00069 0.595
MOD_GSK3_1 243 250 PF00069 0.740
MOD_GSK3_1 265 272 PF00069 0.536
MOD_GSK3_1 280 287 PF00069 0.453
MOD_GSK3_1 315 322 PF00069 0.457
MOD_N-GLC_1 30 35 PF02516 0.641
MOD_NEK2_1 1 6 PF00069 0.555
MOD_NEK2_1 13 18 PF00069 0.628
MOD_NEK2_1 301 306 PF00069 0.450
MOD_PIKK_1 265 271 PF00454 0.549
MOD_PK_1 312 318 PF00069 0.321
MOD_PKA_2 152 158 PF00069 0.534
MOD_PKA_2 277 283 PF00069 0.490
MOD_PKB_1 70 78 PF00069 0.451
MOD_Plk_1 191 197 PF00069 0.549
MOD_Plk_1 243 249 PF00069 0.514
MOD_Plk_1 259 265 PF00069 0.474
MOD_Plk_4 128 134 PF00069 0.338
MOD_Plk_4 312 318 PF00069 0.401
MOD_ProDKin_1 145 151 PF00069 0.395
MOD_ProDKin_1 182 188 PF00069 0.577
MOD_ProDKin_1 43 49 PF00069 0.570
MOD_SUMO_rev_2 143 149 PF00179 0.479
TRG_DiLeu_BaEn_1 58 63 PF01217 0.508
TRG_DiLeu_BaEn_4 58 64 PF01217 0.481
TRG_DiLeu_BaLyEn_6 207 212 PF01217 0.437
TRG_DiLeu_BaLyEn_6 97 102 PF01217 0.545
TRG_DiLeu_LyEn_5 58 63 PF01217 0.485
TRG_ENDOCYTIC_2 220 223 PF00928 0.429
TRG_ENDOCYTIC_2 282 285 PF00928 0.529
TRG_ER_diArg_1 120 123 PF00400 0.371
TRG_ER_diArg_1 69 72 PF00400 0.425
TRG_Pf-PMV_PEXEL_1 210 215 PF00026 0.496

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P7P6 Leptomonas seymouri 40% 100%
A0A3S7XBN8 Leishmania donovani 88% 100%
A4HPX5 Leishmania braziliensis 63% 99%
A4IDN6 Leishmania infantum 88% 100%
E9ATP1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 81% 99%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS