Putative cytochrome b5 1

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

cytochrome b5 1, putative

Species:

Leishmania major

UniProt:

Q4Q0U6_LEIMA

TriTrypDb:

LmjF.36.4675 , LMJLV39_360058300 , LMJSD75_360058100

Length:

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	3
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	3

Expansion

Sequence features

Q4Q0U6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q0U6

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	2
GO:0020037	heme binding	4	2
GO:0046906	tetrapyrrole binding	3	2
GO:0097159	organic cyclic compound binding	2	2
GO:1901363	heterocyclic compound binding	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	66	70	PF00082	0.408
DEG_Nend_UBRbox_1	1	4	PF02207	0.550
LIG_BRCT_BRCA1_1	52	56	PF00533	0.406
LIG_Clathr_ClatBox_1	42	46	PF01394	0.369
LIG_FHA_2	12	18	PF00498	0.350
LIG_FHA_2	3	9	PF00498	0.350
LIG_LIR_Gen_1	17	27	PF02991	0.366
LIG_LIR_Gen_1	30	39	PF02991	0.363
LIG_LIR_Nem_3	15	21	PF02991	0.338
LIG_SH2_STAT5	4	7	PF00017	0.350
LIG_SH2_STAT5	72	75	PF00017	0.421
LIG_SUMO_SIM_par_1	41	47	PF11976	0.386
LIG_SUMO_SIM_par_1	66	71	PF11976	0.241
LIG_TRAF2_1	5	8	PF00917	0.350
LIG_UBA3_1	42	50	PF00899	0.369
MOD_CK2_1	2	8	PF00069	0.314
MOD_GlcNHglycan	46	49	PF01048	0.494
MOD_NEK2_1	11	16	PF00069	0.403
MOD_PIKK_1	12	18	PF00454	0.337
MOD_PK_1	50	56	PF00069	0.432
MOD_Plk_4	50	56	PF00069	0.415
TRG_ENDOCYTIC_2	18	21	PF00928	0.337

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFL2	Leptomonas seymouri	62%	99%
A0A0S4JHB7	Bodo saltans	43%	93%
A0A3S7XBN0	Leishmania donovani	92%	100%
A4HPY5	Leishmania braziliensis	77%	96%
A4IDP6	Leishmania infantum	92%	100%
D0A9Q4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	66%
E9ATQ2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%