LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Guanine nucleotide-binding protein subunit beta-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Guanine nucleotide-binding protein subunit beta-like protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q0U2_LEIMA
TriTrypDb:
LmjF.36.4710 , LMJLV39_360058600 * , LMJSD75_360058400
Length:
727

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
Term Name Level Count
GO:0005840 ribosome 5 7
GO:0032991 protein-containing complex 1 7
GO:0043226 organelle 2 7
GO:0043228 non-membrane-bounded organelle 3 7
GO:0043229 intracellular organelle 3 7
GO:0043232 intracellular non-membrane-bounded organelle 4 7
GO:0110165 cellular anatomical entity 1 7
GO:1990904 ribonucleoprotein complex 2 7

Expansion

Sequence features

Q4Q0U2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q0U2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 425 429 PF00656 0.455
CLV_C14_Caspase3-7 500 504 PF00656 0.612
CLV_C14_Caspase3-7 668 672 PF00656 0.707
CLV_NRD_NRD_1 181 183 PF00675 0.646
CLV_NRD_NRD_1 223 225 PF00675 0.437
CLV_NRD_NRD_1 273 275 PF00675 0.448
CLV_NRD_NRD_1 365 367 PF00675 0.471
CLV_NRD_NRD_1 402 404 PF00675 0.554
CLV_NRD_NRD_1 475 477 PF00675 0.526
CLV_NRD_NRD_1 543 545 PF00675 0.666
CLV_NRD_NRD_1 55 57 PF00675 0.485
CLV_NRD_NRD_1 611 613 PF00675 0.697
CLV_NRD_NRD_1 697 699 PF00675 0.528
CLV_NRD_NRD_1 710 712 PF00675 0.555
CLV_PCSK_FUR_1 221 225 PF00082 0.515
CLV_PCSK_FUR_1 473 477 PF00082 0.475
CLV_PCSK_FUR_1 708 712 PF00082 0.558
CLV_PCSK_KEX2_1 181 183 PF00082 0.585
CLV_PCSK_KEX2_1 223 225 PF00082 0.510
CLV_PCSK_KEX2_1 273 275 PF00082 0.448
CLV_PCSK_KEX2_1 365 367 PF00082 0.471
CLV_PCSK_KEX2_1 402 404 PF00082 0.554
CLV_PCSK_KEX2_1 472 474 PF00082 0.547
CLV_PCSK_KEX2_1 475 477 PF00082 0.549
CLV_PCSK_KEX2_1 545 547 PF00082 0.665
CLV_PCSK_KEX2_1 55 57 PF00082 0.602
CLV_PCSK_KEX2_1 611 613 PF00082 0.697
CLV_PCSK_KEX2_1 632 634 PF00082 0.723
CLV_PCSK_KEX2_1 683 685 PF00082 0.546
CLV_PCSK_KEX2_1 697 699 PF00082 0.553
CLV_PCSK_KEX2_1 707 709 PF00082 0.552
CLV_PCSK_KEX2_1 710 712 PF00082 0.555
CLV_PCSK_PC1ET2_1 472 474 PF00082 0.582
CLV_PCSK_PC1ET2_1 545 547 PF00082 0.665
CLV_PCSK_PC1ET2_1 55 57 PF00082 0.602
CLV_PCSK_PC1ET2_1 632 634 PF00082 0.723
CLV_PCSK_PC1ET2_1 683 685 PF00082 0.535
CLV_PCSK_PC1ET2_1 707 709 PF00082 0.552
CLV_PCSK_SKI1_1 475 479 PF00082 0.467
CLV_PCSK_SKI1_1 529 533 PF00082 0.574
CLV_PCSK_SKI1_1 582 586 PF00082 0.729
CLV_PCSK_SKI1_1 691 695 PF00082 0.538
CLV_Separin_Metazoa 530 534 PF03568 0.602
DEG_APCC_DBOX_1 364 372 PF00400 0.484
DEG_Nend_UBRbox_2 1 3 PF02207 0.595
DOC_CYCLIN_RxL_1 472 479 PF00134 0.457
DOC_MAPK_gen_1 221 228 PF00069 0.508
DOC_MAPK_gen_1 533 541 PF00069 0.615
DOC_MAPK_gen_1 694 703 PF00069 0.517
DOC_PP1_RVXF_1 543 550 PF00149 0.588
DOC_PP1_RVXF_1 697 704 PF00149 0.528
DOC_USP7_MATH_1 177 181 PF00917 0.665
DOC_USP7_MATH_1 499 503 PF00917 0.741
DOC_USP7_MATH_1 573 577 PF00917 0.729
DOC_USP7_MATH_1 590 594 PF00917 0.571
DOC_USP7_MATH_1 607 611 PF00917 0.661
DOC_USP7_MATH_1 654 658 PF00917 0.646
DOC_USP7_MATH_1 666 670 PF00917 0.746
DOC_USP7_MATH_1 98 102 PF00917 0.553
DOC_USP7_UBL2_3 567 571 PF12436 0.660
DOC_WW_Pin1_4 299 304 PF00397 0.399
DOC_WW_Pin1_4 503 508 PF00397 0.604
DOC_WW_Pin1_4 593 598 PF00397 0.695
LIG_14-3-3_CanoR_1 121 126 PF00244 0.492
LIG_14-3-3_CanoR_1 412 422 PF00244 0.487
LIG_14-3-3_CanoR_1 56 60 PF00244 0.509
LIG_Actin_WH2_2 119 134 PF00022 0.569
LIG_APCC_ABBA_1 226 231 PF00400 0.493
LIG_APCC_ABBAyCdc20_2 544 550 PF00400 0.592
LIG_BRCT_BRCA1_1 103 107 PF00533 0.492
LIG_BRCT_BRCA1_1 72 76 PF00533 0.556
LIG_FHA_1 120 126 PF00498 0.553
LIG_FHA_1 13 19 PF00498 0.701
LIG_FHA_1 183 189 PF00498 0.662
LIG_FHA_1 46 52 PF00498 0.518
LIG_FHA_1 637 643 PF00498 0.583
LIG_FHA_2 206 212 PF00498 0.391
LIG_FHA_2 457 463 PF00498 0.546
LIG_FHA_2 512 518 PF00498 0.717
LIG_LIR_Apic_2 314 318 PF02991 0.433
LIG_LIR_Gen_1 432 439 PF02991 0.492
LIG_LIR_Nem_3 432 436 PF02991 0.476
LIG_Pex14_1 315 319 PF04695 0.428
LIG_PTAP_UEV_1 183 188 PF05743 0.524
LIG_PTB_Apo_2 288 295 PF02174 0.496
LIG_SH2_SRC 227 230 PF00017 0.453
LIG_SH2_STAP1 260 264 PF00017 0.415
LIG_SH2_STAT3 235 238 PF00017 0.391
LIG_SH2_STAT3 89 92 PF00017 0.576
LIG_SH2_STAT5 113 116 PF00017 0.492
LIG_SH2_STAT5 227 230 PF00017 0.462
LIG_SH2_STAT5 235 238 PF00017 0.367
LIG_SH2_STAT5 241 244 PF00017 0.397
LIG_SH2_STAT5 376 379 PF00017 0.728
LIG_SH2_STAT5 399 402 PF00017 0.586
LIG_SH3_1 181 187 PF00018 0.645
LIG_SH3_2 187 192 PF14604 0.481
LIG_SH3_3 15 21 PF00018 0.677
LIG_SH3_3 181 187 PF00018 0.636
LIG_SH3_3 34 40 PF00018 0.481
LIG_SH3_3 60 66 PF00018 0.543
LIG_SH3_3 601 607 PF00018 0.651
LIG_SUMO_SIM_anti_2 122 127 PF11976 0.501
LIG_SUMO_SIM_par_1 120 127 PF11976 0.571
LIG_SUMO_SIM_par_1 210 219 PF11976 0.401
LIG_SUMO_SIM_par_1 420 425 PF11976 0.464
LIG_TRAF2_1 138 141 PF00917 0.541
LIG_WRC_WIRS_1 332 337 PF05994 0.449
MOD_CK1_1 101 107 PF00069 0.421
MOD_CK1_1 252 258 PF00069 0.389
MOD_CK1_1 287 293 PF00069 0.503
MOD_CK1_1 379 385 PF00069 0.636
MOD_CK1_1 497 503 PF00069 0.678
MOD_CK1_1 505 511 PF00069 0.730
MOD_CK1_1 586 592 PF00069 0.710
MOD_CK1_1 593 599 PF00069 0.641
MOD_CK1_1 615 621 PF00069 0.601
MOD_CK1_1 640 646 PF00069 0.766
MOD_CK1_1 669 675 PF00069 0.742
MOD_CK2_1 100 106 PF00069 0.335
MOD_CK2_1 456 462 PF00069 0.514
MOD_CK2_1 511 517 PF00069 0.654
MOD_CK2_1 55 61 PF00069 0.504
MOD_CK2_1 659 665 PF00069 0.657
MOD_Cter_Amidation 147 150 PF01082 0.697
MOD_GlcNHglycan 115 118 PF01048 0.399
MOD_GlcNHglycan 164 167 PF01048 0.782
MOD_GlcNHglycan 195 198 PF01048 0.359
MOD_GlcNHglycan 251 254 PF01048 0.385
MOD_GlcNHglycan 26 29 PF01048 0.480
MOD_GlcNHglycan 286 289 PF01048 0.480
MOD_GlcNHglycan 371 374 PF01048 0.517
MOD_GlcNHglycan 381 384 PF01048 0.620
MOD_GlcNHglycan 389 392 PF01048 0.634
MOD_GlcNHglycan 424 427 PF01048 0.454
MOD_GlcNHglycan 588 591 PF01048 0.641
MOD_GlcNHglycan 597 600 PF01048 0.582
MOD_GlcNHglycan 614 617 PF01048 0.642
MOD_GlcNHglycan 638 642 PF01048 0.783
MOD_GlcNHglycan 76 79 PF01048 0.632
MOD_GlcNHglycan 98 101 PF01048 0.344
MOD_GSK3_1 115 122 PF00069 0.335
MOD_GSK3_1 12 19 PF00069 0.586
MOD_GSK3_1 151 158 PF00069 0.629
MOD_GSK3_1 162 169 PF00069 0.746
MOD_GSK3_1 248 255 PF00069 0.381
MOD_GSK3_1 283 290 PF00069 0.459
MOD_GSK3_1 374 381 PF00069 0.606
MOD_GSK3_1 493 500 PF00069 0.677
MOD_GSK3_1 502 509 PF00069 0.668
MOD_GSK3_1 580 587 PF00069 0.723
MOD_GSK3_1 591 598 PF00069 0.656
MOD_GSK3_1 615 622 PF00069 0.690
MOD_GSK3_1 636 643 PF00069 0.757
MOD_GSK3_1 655 662 PF00069 0.700
MOD_GSK3_1 70 77 PF00069 0.673
MOD_GSK3_1 96 103 PF00069 0.335
MOD_N-GLC_1 155 160 PF02516 0.545
MOD_N-GLC_1 284 289 PF02516 0.447
MOD_N-GLC_1 290 295 PF02516 0.494
MOD_N-GLC_1 338 343 PF02516 0.464
MOD_N-GLC_1 385 390 PF02516 0.633
MOD_N-GLC_1 701 706 PF02516 0.539
MOD_N-GLC_2 199 201 PF02516 0.398
MOD_N-GLC_2 367 369 PF02516 0.457
MOD_NEK2_1 248 253 PF00069 0.392
MOD_NEK2_1 283 288 PF00069 0.426
MOD_NEK2_1 346 351 PF00069 0.411
MOD_NEK2_1 422 427 PF00069 0.453
MOD_NEK2_1 642 647 PF00069 0.700
MOD_NEK2_2 331 336 PF00069 0.556
MOD_PIKK_1 234 240 PF00454 0.413
MOD_PIKK_1 566 572 PF00454 0.608
MOD_PK_1 121 127 PF00069 0.335
MOD_PK_1 268 274 PF00069 0.431
MOD_PK_1 55 61 PF00069 0.622
MOD_PKA_1 55 61 PF00069 0.622
MOD_PKA_1 565 571 PF00069 0.732
MOD_PKA_2 177 183 PF00069 0.780
MOD_PKA_2 413 419 PF00069 0.464
MOD_PKA_2 55 61 PF00069 0.504
MOD_Plk_1 119 125 PF00069 0.335
MOD_Plk_1 16 22 PF00069 0.548
MOD_Plk_1 268 274 PF00069 0.431
MOD_Plk_1 290 296 PF00069 0.482
MOD_Plk_1 337 343 PF00069 0.503
MOD_Plk_1 374 380 PF00069 0.618
MOD_Plk_1 637 643 PF00069 0.678
MOD_Plk_1 69 75 PF00069 0.548
MOD_Plk_1 701 707 PF00069 0.539
MOD_Plk_2-3 511 517 PF00069 0.678
MOD_Plk_2-3 550 556 PF00069 0.721
MOD_Plk_4 290 296 PF00069 0.501
MOD_Plk_4 70 76 PF00069 0.548
MOD_ProDKin_1 299 305 PF00069 0.398
MOD_ProDKin_1 503 509 PF00069 0.603
MOD_ProDKin_1 593 599 PF00069 0.692
MOD_SUMO_for_1 693 696 PF00179 0.500
TRG_DiLeu_BaLyEn_6 473 478 PF01217 0.537
TRG_ENDOCYTIC_2 319 322 PF00928 0.427
TRG_ER_diArg_1 223 225 PF00400 0.564
TRG_ER_diArg_1 272 274 PF00400 0.559
TRG_ER_diArg_1 364 366 PF00400 0.481
TRG_ER_diArg_1 402 405 PF00400 0.559
TRG_ER_diArg_1 412 415 PF00400 0.485
TRG_ER_diArg_1 448 451 PF00400 0.582
TRG_ER_diArg_1 475 477 PF00400 0.526
TRG_ER_diArg_1 532 535 PF00400 0.651
TRG_ER_diArg_1 543 546 PF00400 0.580
TRG_ER_diArg_1 611 613 PF00400 0.697
TRG_ER_diArg_1 708 711 PF00400 0.558
TRG_NES_CRM1_1 2 14 PF08389 0.601
TRG_NLS_Bipartite_1 683 702 PF00514 0.525
TRG_NLS_MonoCore_2 629 634 PF00514 0.644
TRG_NLS_MonoExtC_3 54 60 PF00514 0.547
TRG_NLS_MonoExtN_4 543 548 PF00514 0.679
TRG_NLS_MonoExtN_4 562 569 PF00514 0.703
TRG_NLS_MonoExtN_4 628 635 PF00514 0.652
TRG_NLS_MonoExtN_4 697 702 PF00514 0.524
TRG_Pf-PMV_PEXEL_1 366 370 PF00026 0.469
TRG_Pf-PMV_PEXEL_1 458 462 PF00026 0.545
TRG_Pf-PMV_PEXEL_1 465 469 PF00026 0.512
TRG_Pf-PMV_PEXEL_1 475 479 PF00026 0.555
TRG_Pf-PMV_PEXEL_1 691 695 PF00026 0.519

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I9Z8 Leptomonas seymouri 67% 100%
A0A3S7XBM3 Leishmania donovani 91% 100%
A4HPY8 Leishmania braziliensis 75% 100%
A4IDP9 Leishmania infantum 91% 100%
E9ATQ5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS