Small monomeric GTPase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q0T0_LEIMA

TriTrypDb:

LmjF.36.4830 , LMJLV39_360060000 , LMJSD75_360059700

Length:

472

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q0T0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q0T0

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	308	312	PF00656	0.551
CLV_NRD_NRD_1	182	184	PF00675	0.616
CLV_NRD_NRD_1	223	225	PF00675	0.423
CLV_NRD_NRD_1	330	332	PF00675	0.603
CLV_NRD_NRD_1	342	344	PF00675	0.525
CLV_NRD_NRD_1	37	39	PF00675	0.412
CLV_PCSK_KEX2_1	182	184	PF00082	0.567
CLV_PCSK_KEX2_1	223	225	PF00082	0.423
CLV_PCSK_KEX2_1	330	332	PF00082	0.688
CLV_PCSK_KEX2_1	342	344	PF00082	0.518

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I895	Leptomonas seymouri	56%	95%
A0A3Q8IRK5	Leishmania donovani	91%	100%
A4HQ00	Leishmania braziliensis	71%	99%
A4IDR1	Leishmania infantum	90%	100%
E9ATR7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%

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