Armadillo repeat-containing protein 1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q0K3_LEIMA

TriTrypDb:

LmjF.36.5580 , LMJLV39_360068000 , LMJSD75_360068000

Length:

372

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q0K3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q0K3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	73	77	PF00656	0.526
CLV_NRD_NRD_1	118	120	PF00675	0.551
CLV_NRD_NRD_1	12	14	PF00675	0.521
CLV_NRD_NRD_1	196	198	PF00675	0.642
CLV_NRD_NRD_1	29	31	PF00675	0.372
CLV_NRD_NRD_1	47	49	PF00675	0.402
CLV_PCSK_KEX2_1	118	120	PF00082	0.596
CLV_PCSK_KEX2_1	12	14	PF00082	0.442
CLV_PCSK_KEX2_1	196	198	PF00082	0.641
CLV_PCSK_KEX2_1	29	31	PF00082	0.498
CLV_PCSK_KEX2_1	312	314	PF00082	0.603
CLV_PCSK_PC1ET2_1	312	314	PF00082	0.635
CLV_PCSK_SKI1_1	196	200	PF00082	0.774
CLV_PCSK_SKI1_1	259	263	PF00082	0.488
CLV_PCSK_SKI1_1	350	354	PF00082	0.730
DEG_APCC_DBOX_1	29	37	PF00400	0.460
DEG_SPOP_SBC_1	188	192	PF00917	0.757
DOC_CYCLIN_RxL_1	43	53	PF00134	0.552
DOC_MAPK_gen_1	43	52	PF00069	0.503
DOC_MAPK_MEF2A_6	214	222	PF00069	0.541
DOC_MIT_MIM_1	7	17	PF04212	0.450
DOC_PP2B_LxvP_1	102	105	PF13499	0.526
DOC_PP2B_LxvP_1	222	225	PF13499	0.431
DOC_USP7_MATH_1	142	146	PF00917	0.755
DOC_USP7_MATH_1	188	192	PF00917	0.757
DOC_WW_Pin1_4	134	139	PF00397	0.720
LIG_14-3-3_CanoR_1	196	201	PF00244	0.777
LIG_14-3-3_CanoR_1	244	250	PF00244	0.466
LIG_14-3-3_CanoR_1	259	269	PF00244	0.436
LIG_14-3-3_CanoR_1	29	34	PF00244	0.493
LIG_14-3-3_CanoR_1	338	343	PF00244	0.664
LIG_14-3-3_CanoR_1	48	53	PF00244	0.400
LIG_Actin_WH2_2	191	206	PF00022	0.687
LIG_APCC_ABBA_1	331	336	PF00400	0.620
LIG_BIR_II_1	1	5	PF00653	0.529
LIG_BRCT_BRCA1_1	324	328	PF00533	0.601
LIG_FHA_1	241	247	PF00498	0.424
LIG_FHA_1	97	103	PF00498	0.485
LIG_FHA_2	181	187	PF00498	0.716
LIG_FHA_2	282	288	PF00498	0.606
LIG_FHA_2	357	363	PF00498	0.694
LIG_LIR_Gen_1	157	162	PF02991	0.716
LIG_LIR_Gen_1	172	179	PF02991	0.728
LIG_LIR_Gen_1	276	286	PF02991	0.486
LIG_LIR_Gen_1	325	334	PF02991	0.646
LIG_LIR_Nem_3	157	161	PF02991	0.715
LIG_LIR_Nem_3	172	176	PF02991	0.726
LIG_LIR_Nem_3	276	282	PF02991	0.486
LIG_LIR_Nem_3	325	331	PF02991	0.602
LIG_MYND_1	201	205	PF01753	0.682
LIG_Pex14_2	261	265	PF04695	0.536
LIG_Pex14_2	368	372	PF04695	0.629
LIG_SH2_CRK	158	162	PF00017	0.716
LIG_SH2_GRB2like	279	282	PF00017	0.580
LIG_SH2_NCK_1	87	91	PF00017	0.489
LIG_SH2_SRC	279	282	PF00017	0.554
LIG_SH2_SRC	87	90	PF00017	0.485
LIG_SH2_STAP1	158	162	PF00017	0.716
LIG_SH2_STAP1	249	253	PF00017	0.471
LIG_SH2_STAP1	279	283	PF00017	0.579
LIG_SH2_STAT3	307	310	PF00017	0.671
LIG_SH2_STAT5	193	196	PF00017	0.579
LIG_SH2_STAT5	249	252	PF00017	0.512
LIG_SH2_STAT5	316	319	PF00017	0.533
LIG_SH3_3	130	136	PF00018	0.711
LIG_SUMO_SIM_anti_2	174	180	PF11976	0.757
LIG_SUMO_SIM_anti_2	6	12	PF11976	0.448
LIG_SUMO_SIM_anti_2	63	69	PF11976	0.453
LIG_SUMO_SIM_anti_2	99	104	PF11976	0.523
LIG_SUMO_SIM_par_1	76	83	PF11976	0.524
LIG_TRAF2_1	144	147	PF00917	0.547
LIG_TRAF2_1	352	355	PF00917	0.632
MOD_CK1_1	177	183	PF00069	0.718
MOD_CK1_1	189	195	PF00069	0.719
MOD_CK1_1	23	29	PF00069	0.469
MOD_CK1_1	96	102	PF00069	0.522
MOD_CK2_1	141	147	PF00069	0.784
MOD_CK2_1	231	237	PF00069	0.524
MOD_CK2_1	281	287	PF00069	0.593
MOD_GlcNHglycan	127	130	PF01048	0.632
MOD_GlcNHglycan	179	182	PF01048	0.760
MOD_GlcNHglycan	253	256	PF01048	0.551
MOD_GlcNHglycan	262	265	PF01048	0.513
MOD_GlcNHglycan	284	287	PF01048	0.566
MOD_GlcNHglycan	318	321	PF01048	0.661
MOD_GSK3_1	188	195	PF00069	0.692
MOD_GSK3_1	245	252	PF00069	0.553
MOD_GSK3_1	297	304	PF00069	0.606
MOD_GSK3_1	308	315	PF00069	0.430
MOD_N-GLC_1	297	302	PF02516	0.625
MOD_N-GLC_1	338	343	PF02516	0.606
MOD_N-GLC_1	96	101	PF02516	0.483
MOD_NEK2_1	187	192	PF00069	0.671
MOD_NEK2_1	240	245	PF00069	0.406
MOD_NEK2_1	247	252	PF00069	0.371
MOD_NEK2_1	301	306	PF00069	0.692
MOD_NEK2_1	327	332	PF00069	0.563
MOD_PKA_1	196	202	PF00069	0.726
MOD_PKA_1	29	35	PF00069	0.473
MOD_PKA_1	312	318	PF00069	0.590
MOD_PKA_1	48	54	PF00069	0.398
MOD_PKA_2	196	202	PF00069	0.725
MOD_PKA_2	203	209	PF00069	0.673
MOD_PKA_2	23	29	PF00069	0.462
MOD_PKA_2	312	318	PF00069	0.561
MOD_Plk_1	231	237	PF00069	0.567
MOD_Plk_1	297	303	PF00069	0.639
MOD_Plk_1	338	344	PF00069	0.546
MOD_Plk_1	6	12	PF00069	0.523
MOD_Plk_1	96	102	PF00069	0.486
MOD_Plk_4	157	163	PF00069	0.700
MOD_Plk_4	174	180	PF00069	0.754
MOD_Plk_4	189	195	PF00069	0.719
MOD_Plk_4	216	222	PF00069	0.435
MOD_Plk_4	301	307	PF00069	0.634
MOD_Plk_4	312	318	PF00069	0.517
MOD_Plk_4	327	333	PF00069	0.506
MOD_Plk_4	6	12	PF00069	0.523
MOD_ProDKin_1	134	140	PF00069	0.719
MOD_SUMO_for_1	352	355	PF00179	0.690
TRG_DiLeu_BaEn_1	53	58	PF01217	0.431
TRG_DiLeu_BaEn_1	63	68	PF01217	0.395
TRG_DiLeu_BaEn_4	146	152	PF01217	0.533
TRG_ENDOCYTIC_2	158	161	PF00928	0.716
TRG_ENDOCYTIC_2	279	282	PF00928	0.580
TRG_ER_diArg_1	11	13	PF00400	0.531
TRG_ER_diArg_1	196	198	PF00400	0.651
TRG_Pf-PMV_PEXEL_1	48	53	PF00026	0.499

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P9D5	Leptomonas seymouri	73%	99%
A0A3R7RKF3	Trypanosoma rangeli	36%	100%
A0A3S7XBW0	Leishmania donovani	94%	100%
A4HQ74	Leishmania braziliensis	81%	100%
A4IDX2	Leishmania infantum	95%	100%
D0A445	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
E9ATZ3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
V5B3M7	Trypanosoma cruzi	36%	100%