Mkiaa0324 protein-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

mkiaa0324 protein-like protein

Species:

Leishmania major

UniProt:

Q4Q0H9_LEIMA

TriTrypDb:

LmjF.36.5820 , LMJLV39_360070600 , LMJSD75_360070600

Length:

500

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q0H9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q0H9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	103	105	PF00675	0.699
CLV_NRD_NRD_1	111	113	PF00675	0.643
CLV_NRD_NRD_1	12	14	PF00675	0.522
CLV_NRD_NRD_1	132	134	PF00675	0.600
CLV_NRD_NRD_1	175	177	PF00675	0.536
CLV_NRD_NRD_1	193	195	PF00675	0.579
CLV_NRD_NRD_1	199	201	PF00675	0.543
CLV_NRD_NRD_1	204	206	PF00675	0.753
CLV_NRD_NRD_1	211	213	PF00675	0.651
CLV_NRD_NRD_1	217	219	PF00675	0.640
CLV_NRD_NRD_1	248	250	PF00675	0.694
CLV_NRD_NRD_1	254	256	PF00675	0.653
CLV_NRD_NRD_1	266	268	PF00675	0.564
CLV_NRD_NRD_1	294	296	PF00675	0.723
CLV_NRD_NRD_1	302	304	PF00675	0.586
CLV_NRD_NRD_1	318	320	PF00675	0.527
CLV_NRD_NRD_1	323	325	PF00675	0.702
CLV_NRD_NRD_1	33	35	PF00675	0.544
CLV_NRD_NRD_1	331	333	PF00675	0.607
CLV_NRD_NRD_1	376	378	PF00675	0.588
CLV_NRD_NRD_1	404	406	PF00675	0.678
CLV_PCSK_FUR_1	178	182	PF00082	0.487
CLV_PCSK_FUR_1	194	198	PF00082	0.683
CLV_PCSK_FUR_1	246	250	PF00082	0.637
CLV_PCSK_KEX2_1	103	105	PF00082	0.715
CLV_PCSK_KEX2_1	110	112	PF00082	0.755
CLV_PCSK_KEX2_1	12	14	PF00082	0.617
CLV_PCSK_KEX2_1	132	134	PF00082	0.600
CLV_PCSK_KEX2_1	144	146	PF00082	0.610
CLV_PCSK_KEX2_1	163	165	PF00082	0.323
CLV_PCSK_KEX2_1	177	179	PF00082	0.546
CLV_PCSK_KEX2_1	180	182	PF00082	0.562
CLV_PCSK_KEX2_1	192	194	PF00082	0.638
CLV_PCSK_KEX2_1	196	198	PF00082	0.476
CLV_PCSK_KEX2_1	204	206	PF00082	0.547
CLV_PCSK_KEX2_1	245	247	PF00082	0.608
CLV_PCSK_KEX2_1	248	250	PF00082	0.633
CLV_PCSK_KEX2_1	254	256	PF00082	0.602
CLV_PCSK_KEX2_1	258	260	PF00082	0.592
CLV_PCSK_KEX2_1	266	268	PF00082	0.546
CLV_PCSK_KEX2_1	274	276	PF00082	0.522
CLV_PCSK_KEX2_1	301	303	PF00082	0.617
CLV_PCSK_KEX2_1	318	320	PF00082	0.481
CLV_PCSK_KEX2_1	323	325	PF00082	0.615
CLV_PCSK_KEX2_1	330	332	PF00082	0.601
CLV_PCSK_KEX2_1	376	378	PF00082	0.588
CLV_PCSK_KEX2_1	387	389	PF00082	0.476
CLV_PCSK_KEX2_1	406	408	PF00082	0.620
CLV_PCSK_KEX2_1	484	486	PF00082	0.619
CLV_PCSK_PC1ET2_1	103	105	PF00082	0.656
CLV_PCSK_PC1ET2_1	110	112	PF00082	0.755
CLV_PCSK_PC1ET2_1	144	146	PF00082	0.637
CLV_PCSK_PC1ET2_1	163	165	PF00082	0.323
CLV_PCSK_PC1ET2_1	177	179	PF00082	0.546
CLV_PCSK_PC1ET2_1	180	182	PF00082	0.562
CLV_PCSK_PC1ET2_1	196	198	PF00082	0.605
CLV_PCSK_PC1ET2_1	245	247	PF00082	0.569
CLV_PCSK_PC1ET2_1	258	260	PF00082	0.601
CLV_PCSK_PC1ET2_1	274	276	PF00082	0.748
CLV_PCSK_PC1ET2_1	301	303	PF00082	0.617
CLV_PCSK_PC1ET2_1	323	325	PF00082	0.727
CLV_PCSK_PC1ET2_1	387	389	PF00082	0.534
CLV_PCSK_PC1ET2_1	406	408	PF00082	0.620
CLV_PCSK_PC1ET2_1	484	486	PF00082	0.587
CLV_PCSK_PC7_1	140	146	PF00082	0.521
CLV_PCSK_PC7_1	176	182	PF00082	0.568
CLV_PCSK_PC7_1	192	198	PF00082	0.583
CLV_PCSK_PC7_1	200	206	PF00082	0.607
CLV_PCSK_PC7_1	254	260	PF00082	0.699
CLV_PCSK_PC7_1	319	325	PF00082	0.572
CLV_PCSK_SKI1_1	118	122	PF00082	0.625
CLV_PCSK_SKI1_1	144	148	PF00082	0.549
CLV_PCSK_SKI1_1	177	181	PF00082	0.511
CLV_PCSK_SKI1_1	196	200	PF00082	0.611
CLV_PCSK_SKI1_1	205	209	PF00082	0.604
CLV_PCSK_SKI1_1	213	217	PF00082	0.666
CLV_PCSK_SKI1_1	279	283	PF00082	0.647
CLV_PCSK_SKI1_1	359	363	PF00082	0.466
CLV_PCSK_SKI1_1	435	439	PF00082	0.470
CLV_PCSK_SKI1_1	485	489	PF00082	0.465
CLV_PCSK_SKI1_1	71	75	PF00082	0.467
CLV_PCSK_SKI1_1	79	83	PF00082	0.539
CLV_Separin_Metazoa	129	133	PF03568	0.572
DEG_APCC_DBOX_1	139	147	PF00400	0.523
DEG_Nend_Nbox_1	1	3	PF02207	0.569
DOC_CYCLIN_yClb5_NLxxxL_5	140	147	PF00134	0.490
DOC_CYCLIN_yCln2_LP_2	418	424	PF00134	0.601
DOC_MAPK_gen_1	103	109	PF00069	0.648
DOC_MAPK_gen_1	144	151	PF00069	0.639
DOC_MAPK_gen_1	163	171	PF00069	0.328
DOC_MAPK_gen_1	254	265	PF00069	0.692
DOC_MAPK_gen_1	330	339	PF00069	0.521
DOC_MAPK_MEF2A_6	163	171	PF00069	0.471
DOC_MAPK_MEF2A_6	330	339	PF00069	0.521
DOC_MAPK_RevD_3	261	275	PF00069	0.677
DOC_PP2B_LxvP_1	159	162	PF13499	0.610
DOC_PP2B_LxvP_1	418	421	PF13499	0.553
DOC_PP4_FxxP_1	54	57	PF00568	0.442
DOC_USP7_MATH_1	15	19	PF00917	0.468
DOC_USP7_MATH_1	203	207	PF00917	0.687
DOC_USP7_MATH_1	214	218	PF00917	0.585
DOC_USP7_MATH_1	233	237	PF00917	0.595
DOC_USP7_MATH_1	273	277	PF00917	0.766
DOC_USP7_MATH_1	8	12	PF00917	0.618
DOC_USP7_MATH_1	89	93	PF00917	0.640
DOC_USP7_UBL2_3	484	488	PF12436	0.571
DOC_USP7_UBL2_3	71	75	PF12436	0.531
DOC_WW_Pin1_4	118	123	PF00397	0.523
DOC_WW_Pin1_4	274	279	PF00397	0.602
DOC_WW_Pin1_4	406	411	PF00397	0.705
LIG_14-3-3_CanoR_1	155	160	PF00244	0.530
LIG_14-3-3_CanoR_1	181	187	PF00244	0.490
LIG_14-3-3_CanoR_1	234	244	PF00244	0.693
LIG_14-3-3_CanoR_1	259	264	PF00244	0.681
LIG_14-3-3_CanoR_1	34	43	PF00244	0.484
LIG_14-3-3_CanoR_1	477	481	PF00244	0.571
LIG_14-3-3_CanoR_1	53	57	PF00244	0.464
LIG_BRCT_BRCA1_1	444	448	PF00533	0.513
LIG_EH_1	445	449	PF12763	0.441
LIG_FHA_1	104	110	PF00498	0.523
LIG_FHA_1	344	350	PF00498	0.475
LIG_FHA_1	356	362	PF00498	0.520
LIG_FHA_1	36	42	PF00498	0.500
LIG_FHA_1	366	372	PF00498	0.432
LIG_FHA_1	380	386	PF00498	0.445
LIG_FHA_1	72	78	PF00498	0.541
LIG_IBAR_NPY_1	334	336	PF08397	0.486
LIG_LIR_Gen_1	121	131	PF02991	0.454
LIG_LIR_Gen_1	451	459	PF02991	0.430
LIG_LIR_Nem_3	121	126	PF02991	0.465
LIG_LIR_Nem_3	18	23	PF02991	0.532
LIG_LIR_Nem_3	451	455	PF02991	0.410
LIG_LYPXL_S_1	23	27	PF13949	0.411
LIG_LYPXL_yS_3	24	27	PF13949	0.423
LIG_SH2_CRK	20	24	PF00017	0.459
LIG_SH2_CRK	452	456	PF00017	0.423
LIG_SH2_STAP1	452	456	PF00017	0.423
LIG_SH2_STAT5	336	339	PF00017	0.466
LIG_SH3_1	254	260	PF00018	0.699
LIG_SH3_3	20	26	PF00018	0.569
LIG_SH3_3	254	260	PF00018	0.699
LIG_SH3_3	347	353	PF00018	0.517
LIG_SH3_3	392	398	PF00018	0.589
LIG_SH3_3	418	424	PF00018	0.765
LIG_TRAF2_1	30	33	PF00917	0.438
LIG_WRC_WIRS_1	16	21	PF05994	0.543
LIG_WW_1	440	443	PF00397	0.509
MOD_CDK_SPK_2	274	279	PF00069	0.602
MOD_CDK_SPK_2	406	411	PF00069	0.590
MOD_CK1_1	277	283	PF00069	0.601
MOD_Cter_Amidation	115	118	PF01082	0.607
MOD_GlcNHglycan	201	204	PF01048	0.626
MOD_GlcNHglycan	205	208	PF01048	0.672
MOD_GlcNHglycan	237	240	PF01048	0.677
MOD_GlcNHglycan	326	329	PF01048	0.674
MOD_GlcNHglycan	402	405	PF01048	0.705
MOD_GlcNHglycan	485	488	PF01048	0.488
MOD_GlcNHglycan	54	57	PF01048	0.573
MOD_GSK3_1	131	138	PF00069	0.567
MOD_GSK3_1	180	187	PF00069	0.557
MOD_GSK3_1	192	199	PF00069	0.570
MOD_GSK3_1	273	280	PF00069	0.597
MOD_GSK3_1	363	370	PF00069	0.531
MOD_GSK3_1	386	393	PF00069	0.626
MOD_GSK3_1	99	106	PF00069	0.718
MOD_NEK2_1	131	136	PF00069	0.502
MOD_NEK2_1	182	187	PF00069	0.488
MOD_NEK2_1	2	7	PF00069	0.556
MOD_NEK2_1	343	348	PF00069	0.462
MOD_NEK2_1	448	453	PF00069	0.408
MOD_NEK2_1	77	82	PF00069	0.622
MOD_NEK2_1	96	101	PF00069	0.522
MOD_NEK2_2	15	20	PF00069	0.541
MOD_PK_1	157	163	PF00069	0.539
MOD_PK_1	259	265	PF00069	0.689
MOD_PKA_1	103	109	PF00069	0.521
MOD_PKA_1	180	186	PF00069	0.547
MOD_PKA_1	192	198	PF00069	0.590
MOD_PKA_1	323	329	PF00069	0.652
MOD_PKA_2	131	137	PF00069	0.598
MOD_PKA_2	180	186	PF00069	0.556
MOD_PKA_2	192	198	PF00069	0.700
MOD_PKA_2	199	205	PF00069	0.539
MOD_PKA_2	233	239	PF00069	0.657
MOD_PKA_2	288	294	PF00069	0.643
MOD_PKA_2	304	310	PF00069	0.559
MOD_PKA_2	317	323	PF00069	0.518
MOD_PKA_2	343	349	PF00069	0.425
MOD_PKA_2	379	385	PF00069	0.563
MOD_PKA_2	400	406	PF00069	0.714
MOD_PKA_2	476	482	PF00069	0.608
MOD_PKA_2	52	58	PF00069	0.509
MOD_PKA_2	97	103	PF00069	0.700
MOD_PKB_1	155	163	PF00069	0.544
MOD_Plk_4	15	21	PF00069	0.547
MOD_ProDKin_1	118	124	PF00069	0.514
MOD_ProDKin_1	274	280	PF00069	0.604
MOD_ProDKin_1	406	412	PF00069	0.706
MOD_SUMO_rev_2	29	36	PF00179	0.426
MOD_SUMO_rev_2	479	486	PF00179	0.597
TRG_DiLeu_BaLyEn_6	167	172	PF01217	0.468
TRG_DiLeu_BaLyEn_6	454	459	PF01217	0.494
TRG_ENDOCYTIC_2	20	23	PF00928	0.407
TRG_ENDOCYTIC_2	24	27	PF00928	0.445
TRG_ENDOCYTIC_2	336	339	PF00928	0.463
TRG_ENDOCYTIC_2	340	343	PF00928	0.453
TRG_ENDOCYTIC_2	452	455	PF00928	0.416
TRG_ER_diArg_1	12	14	PF00400	0.466
TRG_ER_diArg_1	131	133	PF00400	0.592
TRG_ER_diArg_1	192	194	PF00400	0.638
TRG_ER_diArg_1	246	249	PF00400	0.676
TRG_ER_diArg_1	254	256	PF00400	0.680
TRG_ER_diArg_1	265	267	PF00400	0.536
TRG_ER_diArg_1	302	305	PF00400	0.623
TRG_ER_diArg_1	330	332	PF00400	0.658
TRG_ER_diArg_1	376	378	PF00400	0.588
TRG_NLS_Bipartite_1	163	181	PF00514	0.475
TRG_NLS_Bipartite_1	228	249	PF00514	0.673
TRG_NLS_Bipartite_1	387	409	PF00514	0.538
TRG_NLS_MonoExtC_3	176	181	PF00514	0.598
TRG_NLS_MonoExtC_3	244	249	PF00514	0.646
TRG_NLS_MonoExtC_3	300	305	PF00514	0.683
TRG_NLS_MonoExtN_4	174	181	PF00514	0.521
TRG_NLS_MonoExtN_4	243	249	PF00514	0.650
TRG_Pf-PMV_PEXEL_1	170	175	PF00026	0.568
TRG_Pf-PMV_PEXEL_1	302	306	PF00026	0.489

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I3V1	Leptomonas seymouri	41%	100%
A0A3Q8IK24	Leishmania donovani	88%	100%
A4HQ98	Leishmania braziliensis	63%	100%
A4IDZ5	Leishmania infantum	87%	100%
E9AU16	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%