Putative kinetoplast-associated protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

kinetoplast-associated protein, putative

Species:

Leishmania major

UniProt:

Q4Q0H6_LEIMA

TriTrypDb:

LmjF.36.5845 , LMJLV39_360070900 , LMJSD75_360070900

Length:

124

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q0H6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q0H6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	7	9	PF00675	0.487
CLV_NRD_NRD_1	70	72	PF00675	0.496
CLV_PCSK_KEX2_1	56	58	PF00082	0.536
CLV_PCSK_KEX2_1	7	9	PF00082	0.487
CLV_PCSK_KEX2_1	70	72	PF00082	0.483
CLV_PCSK_PC1ET2_1	56	58	PF00082	0.476
CLV_PCSK_PC1ET2_1	70	72	PF00082	0.483
CLV_PCSK_PC7_1	3	9	PF00082	0.654
CLV_PCSK_SKI1_1	51	55	PF00082	0.556
CLV_PCSK_SKI1_1	71	75	PF00082	0.505
DEG_Nend_Nbox_1	1	3	PF02207	0.683
DOC_ANK_TNKS_1	6	13	PF00023	0.603
DOC_CDC14_PxL_1	99	107	PF14671	0.503
DOC_USP7_MATH_1	60	64	PF00917	0.646
DOC_USP7_MATH_1	87	91	PF00917	0.383
DOC_USP7_UBL2_3	109	113	PF12436	0.570
DOC_USP7_UBL2_3	22	26	PF12436	0.529
DOC_USP7_UBL2_3	37	41	PF12436	0.576
DOC_USP7_UBL2_3	70	74	PF12436	0.733
LIG_14-3-3_CanoR_1	35	43	PF00244	0.576
LIG_14-3-3_CanoR_1	65	73	PF00244	0.599
LIG_14-3-3_CterR_2	121	124	PF00244	0.444
LIG_FHA_1	37	43	PF00498	0.496
LIG_LIR_Gen_1	86	96	PF02991	0.536
LIG_LIR_Nem_3	40	46	PF02991	0.583
LIG_LIR_Nem_3	86	91	PF02991	0.547
LIG_PCNA_PIPBox_1	108	117	PF02747	0.576
LIG_SH2_CRK	43	47	PF00017	0.581
LIG_SH2_STAP1	14	18	PF00017	0.543
LIG_SH2_STAP1	88	92	PF00017	0.555
LIG_UBA3_1	16	22	PF00899	0.479
LIG_WRC_WIRS_1	88	93	PF05994	0.367
MOD_GlcNHglycan	46	49	PF01048	0.581
MOD_GlcNHglycan	85	88	PF01048	0.528
MOD_GSK3_1	42	49	PF00069	0.488
MOD_GSK3_1	79	86	PF00069	0.664
MOD_NEK2_1	42	47	PF00069	0.504
MOD_NEK2_2	12	17	PF00069	0.538
MOD_NEK2_2	60	65	PF00069	0.657
MOD_PIKK_1	65	71	PF00454	0.627
MOD_PK_1	28	34	PF00069	0.511
MOD_PKA_2	79	85	PF00069	0.604
MOD_Plk_4	12	18	PF00069	0.542
MOD_Plk_4	87	93	PF00069	0.374
MOD_SUMO_for_1	73	76	PF00179	0.659
TRG_ENDOCYTIC_2	14	17	PF00928	0.537
TRG_ENDOCYTIC_2	43	46	PF00928	0.583
TRG_ENDOCYTIC_2	88	91	PF00928	0.521
TRG_ER_diArg_1	6	8	PF00400	0.652
TRG_NLS_Bipartite_1	56	75	PF00514	0.441
TRG_NLS_MonoExtC_3	69	74	PF00514	0.494
TRG_NLS_MonoExtN_4	67	74	PF00514	0.488

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I8Y9	Leptomonas seymouri	33%	73%
A0A0N1IC67	Leptomonas seymouri	68%	98%
A0A0S4IRH7	Bodo saltans	36%	100%
A0A0S4J5T0	Bodo saltans	30%	89%
A0A0S4J9G1	Bodo saltans	38%	100%
A0A0S4JC95	Bodo saltans	43%	100%
A0A0S4JL06	Bodo saltans	32%	100%
A0A0S4JT41	Bodo saltans	48%	100%
A0A1X0NLS3	Trypanosomatidae	55%	100%
A0A1X0NNA1	Trypanosomatidae	30%	70%
A0A1X0NNA5	Trypanosomatidae	56%	100%
A0A1X0NND5	Trypanosomatidae	56%	96%
A0A3Q8ILR8	Leishmania donovani	94%	100%
A0A3Q8IPT9	Leishmania donovani	32%	77%
A0A3R7KKP8	Trypanosoma rangeli	54%	100%
A0A3R7MMA3	Trypanosoma rangeli	56%	92%
A0A3R7NF04	Trypanosoma rangeli	32%	66%
A0A422NSG2	Trypanosoma rangeli	56%	95%
A0A422NSJ6	Trypanosoma rangeli	56%	100%
A4HQA1	Leishmania braziliensis	81%	100%
A4HQA9	Leishmania braziliensis	35%	75%
A4IDZ7	Leishmania infantum	95%	100%
A4IE05	Leishmania infantum	32%	77%
D0A408	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	51%	67%
D0A410	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	51%	98%
E9AU19	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
E9AU27	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	77%
Q07053	Crithidia fasciculata	70%	97%
Q4Q0G8	Leishmania major	37%	100%
V5BT80	Trypanosoma cruzi	33%	67%
V5DK57	Trypanosoma cruzi	56%	97%