Protein kinase domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

flagellum targeting protein kharon1, putative

Species:

Leishmania major

UniProt:

Q4Q0H5_LEIMA

TriTrypDb:

LmjF.36.5850 , LMJLV39_360071000 , LMJSD75_360071000

Length:

537

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q0H5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q0H5

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	145	149	PF00656	0.497
CLV_C14_Caspase3-7	415	419	PF00656	0.546
CLV_NRD_NRD_1	103	105	PF00675	0.694
CLV_NRD_NRD_1	140	142	PF00675	0.654
CLV_NRD_NRD_1	177	179	PF00675	0.643
CLV_NRD_NRD_1	18	20	PF00675	0.474
CLV_NRD_NRD_1	345	347	PF00675	0.673
CLV_NRD_NRD_1	355	357	PF00675	0.639
CLV_NRD_NRD_1	439	441	PF00675	0.743
CLV_NRD_NRD_1	78	80	PF00675	0.646

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P9C6	Leptomonas seymouri	51%	100%
A0A3Q8IL75	Leishmania donovani	77%	100%
A4HQA3	Leishmania braziliensis	60%	100%
A4IDZ8	Leishmania infantum	77%	100%
E9AU20	Leishmania mexicana (strain MHOM/GT/2001/U1103)	73%	100%

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