LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q0G5_LEIMA
TriTrypDb:
LmjF.36.5950 , LMJLV39_360072300 * , LMJSD75_360072300
Length:
389

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q0G5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q0G5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 239 243 PF00656 0.648
CLV_C14_Caspase3-7 24 28 PF00656 0.535
CLV_NRD_NRD_1 120 122 PF00675 0.501
CLV_NRD_NRD_1 302 304 PF00675 0.592
CLV_PCSK_KEX2_1 119 121 PF00082 0.519
CLV_PCSK_KEX2_1 302 304 PF00082 0.692
CLV_PCSK_SKI1_1 11 15 PF00082 0.587
DEG_COP1_1 239 247 PF00400 0.578
DOC_CKS1_1 244 249 PF01111 0.676
DOC_CKS1_1 270 275 PF01111 0.564
DOC_MAPK_MEF2A_6 200 207 PF00069 0.571
DOC_USP7_MATH_1 213 217 PF00917 0.480
DOC_USP7_MATH_1 229 233 PF00917 0.537
DOC_USP7_MATH_1 245 249 PF00917 0.637
DOC_USP7_MATH_1 25 29 PF00917 0.546
DOC_USP7_MATH_1 311 315 PF00917 0.661
DOC_USP7_MATH_1 385 389 PF00917 0.607
DOC_WW_Pin1_4 177 182 PF00397 0.661
DOC_WW_Pin1_4 225 230 PF00397 0.760
DOC_WW_Pin1_4 243 248 PF00397 0.546
DOC_WW_Pin1_4 269 274 PF00397 0.585
DOC_WW_Pin1_4 307 312 PF00397 0.641
DOC_WW_Pin1_4 41 46 PF00397 0.627
DOC_WW_Pin1_4 73 78 PF00397 0.486
LIG_14-3-3_CanoR_1 155 160 PF00244 0.637
LIG_14-3-3_CanoR_1 80 87 PF00244 0.542
LIG_BIR_III_4 186 190 PF00653 0.598
LIG_BRCT_BRCA1_1 215 219 PF00533 0.516
LIG_DLG_GKlike_1 155 163 PF00625 0.613
LIG_FHA_1 190 196 PF00498 0.591
LIG_FHA_1 199 205 PF00498 0.530
LIG_FHA_1 287 293 PF00498 0.674
LIG_FHA_1 310 316 PF00498 0.591
LIG_FHA_1 338 344 PF00498 0.581
LIG_FHA_2 112 118 PF00498 0.522
LIG_FHA_2 215 221 PF00498 0.574
LIG_FHA_2 253 259 PF00498 0.578
LIG_FHA_2 74 80 PF00498 0.453
LIG_LIR_Gen_1 216 227 PF02991 0.557
LIG_LIR_Nem_3 146 152 PF02991 0.548
LIG_LIR_Nem_3 216 222 PF02991 0.552
LIG_MYND_3 320 324 PF01753 0.576
LIG_Pex14_2 219 223 PF04695 0.561
LIG_Pex14_2 68 72 PF04695 0.537
LIG_PTAP_UEV_1 246 251 PF05743 0.622
LIG_Rb_pABgroove_1 363 371 PF01858 0.441
LIG_SH2_STAP1 371 375 PF00017 0.536
LIG_SH3_2 178 183 PF14604 0.548
LIG_SH3_3 175 181 PF00018 0.555
LIG_SH3_3 241 247 PF00018 0.588
LIG_SH3_3 267 273 PF00018 0.652
LIG_SH3_3 305 311 PF00018 0.656
LIG_SH3_3 315 321 PF00018 0.546
LIG_SH3_5 367 371 PF00018 0.451
LIG_SUMO_SIM_par_1 191 199 PF11976 0.583
LIG_TRAF2_1 60 63 PF00917 0.532
LIG_TRFH_1 363 367 PF08558 0.481
MOD_CDC14_SPxK_1 180 183 PF00782 0.635
MOD_CDK_SPxK_1 177 183 PF00069 0.636
MOD_CDK_SPxxK_3 73 80 PF00069 0.476
MOD_CK1_1 151 157 PF00069 0.683
MOD_CK1_1 158 164 PF00069 0.725
MOD_CK1_1 179 185 PF00069 0.654
MOD_CK1_1 198 204 PF00069 0.465
MOD_CK1_1 232 238 PF00069 0.548
MOD_CK1_1 275 281 PF00069 0.683
MOD_CK1_1 306 312 PF00069 0.604
MOD_CK1_1 314 320 PF00069 0.595
MOD_CK1_1 337 343 PF00069 0.558
MOD_CK1_1 43 49 PF00069 0.588
MOD_CK1_1 7 13 PF00069 0.557
MOD_CK2_1 111 117 PF00069 0.530
MOD_CK2_1 252 258 PF00069 0.581
MOD_CK2_1 310 316 PF00069 0.594
MOD_CK2_1 57 63 PF00069 0.517
MOD_GlcNHglycan 138 141 PF01048 0.520
MOD_GlcNHglycan 160 163 PF01048 0.625
MOD_GlcNHglycan 170 173 PF01048 0.575
MOD_GlcNHglycan 234 237 PF01048 0.621
MOD_GlcNHglycan 247 250 PF01048 0.791
MOD_GlcNHglycan 27 30 PF01048 0.594
MOD_GlcNHglycan 45 48 PF01048 0.454
MOD_GSK3_1 151 158 PF00069 0.617
MOD_GSK3_1 225 232 PF00069 0.642
MOD_GSK3_1 268 275 PF00069 0.634
MOD_GSK3_1 303 310 PF00069 0.608
MOD_GSK3_1 43 50 PF00069 0.578
MOD_GSK3_1 75 82 PF00069 0.493
MOD_NEK2_1 105 110 PF00069 0.633
MOD_NEK2_1 195 200 PF00069 0.528
MOD_PIKK_1 278 284 PF00454 0.674
MOD_PIKK_1 47 53 PF00454 0.465
MOD_PKA_2 136 142 PF00069 0.570
MOD_PKA_2 337 343 PF00069 0.624
MOD_PKA_2 79 85 PF00069 0.528
MOD_Plk_4 64 70 PF00069 0.560
MOD_ProDKin_1 177 183 PF00069 0.660
MOD_ProDKin_1 225 231 PF00069 0.764
MOD_ProDKin_1 243 249 PF00069 0.543
MOD_ProDKin_1 269 275 PF00069 0.586
MOD_ProDKin_1 307 313 PF00069 0.641
MOD_ProDKin_1 41 47 PF00069 0.621
MOD_ProDKin_1 73 79 PF00069 0.485
MOD_SUMO_for_1 85 88 PF00179 0.576
TRG_DiLeu_BaEn_2 340 346 PF01217 0.545
TRG_ER_diArg_1 118 121 PF00400 0.479
TRG_Pf-PMV_PEXEL_1 120 124 PF00026 0.513

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P903 Leptomonas seymouri 35% 100%
A0A3Q8IGQ8 Leishmania donovani 83% 100%
A4HQB4 Leishmania braziliensis 51% 100%
A4IE08 Leishmania infantum 83% 100%
E9AU30 Leishmania mexicana (strain MHOM/GT/2001/U1103) 80% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS