L6202.3-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

l6202.3-like protein

Species:

Leishmania major

UniProt:

Q4Q0G0_LEIMA

TriTrypDb:

LmjF.36.6000 , LMJLV39_360072800 , LMJSD75_360072800

Length:

852

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q0G0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q0G0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	250	254	PF00656	0.605
CLV_C14_Caspase3-7	313	317	PF00656	0.611
CLV_C14_Caspase3-7	642	646	PF00656	0.593
CLV_C14_Caspase3-7	663	667	PF00656	0.573
CLV_MEL_PAP_1	528	534	PF00089	0.565
CLV_NRD_NRD_1	186	188	PF00675	0.614
CLV_NRD_NRD_1	232	234	PF00675	0.564
CLV_NRD_NRD_1	245	247	PF00675	0.567
CLV_NRD_NRD_1	274	276	PF00675	0.500
CLV_NRD_NRD_1	477	479	PF00675	0.629
CLV_NRD_NRD_1	530	532	PF00675	0.573
CLV_NRD_NRD_1	614	616	PF00675	0.630
CLV_NRD_NRD_1	618	620	PF00675	0.606
CLV_NRD_NRD_1	737	739	PF00675	0.737
CLV_NRD_NRD_1	747	749	PF00675	0.634
CLV_PCSK_FUR_1	230	234	PF00082	0.651
CLV_PCSK_KEX2_1	185	187	PF00082	0.622
CLV_PCSK_KEX2_1	232	234	PF00082	0.536
CLV_PCSK_KEX2_1	245	247	PF00082	0.567
CLV_PCSK_KEX2_1	274	276	PF00082	0.505
CLV_PCSK_KEX2_1	477	479	PF00082	0.586
CLV_PCSK_KEX2_1	530	532	PF00082	0.572
CLV_PCSK_KEX2_1	614	616	PF00082	0.576
CLV_PCSK_KEX2_1	620	622	PF00082	0.521
CLV_PCSK_KEX2_1	628	630	PF00082	0.536
CLV_PCSK_KEX2_1	694	696	PF00082	0.733
CLV_PCSK_KEX2_1	698	700	PF00082	0.712
CLV_PCSK_KEX2_1	704	706	PF00082	0.628
CLV_PCSK_KEX2_1	737	739	PF00082	0.737
CLV_PCSK_KEX2_1	747	749	PF00082	0.634
CLV_PCSK_PC1ET2_1	185	187	PF00082	0.574
CLV_PCSK_PC1ET2_1	620	622	PF00082	0.523
CLV_PCSK_PC1ET2_1	628	630	PF00082	0.556
CLV_PCSK_PC1ET2_1	694	696	PF00082	0.751
CLV_PCSK_PC1ET2_1	698	700	PF00082	0.730
CLV_PCSK_PC1ET2_1	704	706	PF00082	0.646
CLV_PCSK_PC7_1	182	188	PF00082	0.605
CLV_PCSK_PC7_1	733	739	PF00082	0.727
CLV_PCSK_SKI1_1	145	149	PF00082	0.583
CLV_PCSK_SKI1_1	182	186	PF00082	0.543
CLV_PCSK_SKI1_1	260	264	PF00082	0.559
CLV_PCSK_SKI1_1	293	297	PF00082	0.532
CLV_PCSK_SKI1_1	327	331	PF00082	0.565
CLV_PCSK_SKI1_1	33	37	PF00082	0.682
CLV_PCSK_SKI1_1	407	411	PF00082	0.661
CLV_PCSK_SKI1_1	505	509	PF00082	0.636
CLV_PCSK_SKI1_1	558	562	PF00082	0.582
CLV_PCSK_SKI1_1	615	619	PF00082	0.443
CLV_PCSK_SKI1_1	691	695	PF00082	0.740
CLV_PCSK_SKI1_1	704	708	PF00082	0.672
CLV_PCSK_SKI1_1	748	752	PF00082	0.802
DEG_SPOP_SBC_1	428	432	PF00917	0.627
DOC_CDC14_PxL_1	774	782	PF14671	0.687
DOC_CKS1_1	844	849	PF01111	0.606
DOC_CYCLIN_RxL_1	182	193	PF00134	0.667
DOC_MAPK_gen_1	182	190	PF00069	0.567
DOC_MAPK_gen_1	337	346	PF00069	0.647
DOC_MAPK_gen_1	383	391	PF00069	0.630
DOC_MAPK_gen_1	530	536	PF00069	0.604
DOC_MAPK_gen_1	582	590	PF00069	0.633
DOC_MAPK_MEF2A_6	337	346	PF00069	0.594
DOC_MAPK_MEF2A_6	385	393	PF00069	0.634
DOC_MAPK_MEF2A_6	59	68	PF00069	0.626
DOC_USP7_MATH_1	18	22	PF00917	0.517
DOC_USP7_MATH_1	197	201	PF00917	0.591
DOC_USP7_MATH_1	335	339	PF00917	0.555
DOC_USP7_MATH_1	374	378	PF00917	0.615
DOC_USP7_MATH_1	4	8	PF00917	0.747
DOC_USP7_MATH_1	428	432	PF00917	0.669
DOC_USP7_MATH_1	50	54	PF00917	0.607
DOC_USP7_MATH_1	509	513	PF00917	0.673
DOC_USP7_MATH_1	538	542	PF00917	0.578
DOC_USP7_MATH_1	684	688	PF00917	0.728
DOC_USP7_MATH_1	723	727	PF00917	0.682
DOC_USP7_MATH_1	789	793	PF00917	0.802
DOC_USP7_MATH_1	801	805	PF00917	0.489
DOC_USP7_UBL2_3	694	698	PF12436	0.760
DOC_USP7_UBL2_3	704	708	PF12436	0.636
DOC_WW_Pin1_4	361	366	PF00397	0.699
DOC_WW_Pin1_4	424	429	PF00397	0.758
DOC_WW_Pin1_4	675	680	PF00397	0.778
DOC_WW_Pin1_4	707	712	PF00397	0.782
DOC_WW_Pin1_4	717	722	PF00397	0.653
DOC_WW_Pin1_4	752	757	PF00397	0.804
DOC_WW_Pin1_4	769	774	PF00397	0.591
DOC_WW_Pin1_4	843	848	PF00397	0.606
LIG_14-3-3_CanoR_1	10	16	PF00244	0.686
LIG_14-3-3_CanoR_1	145	150	PF00244	0.679
LIG_14-3-3_CanoR_1	186	191	PF00244	0.609
LIG_14-3-3_CanoR_1	222	227	PF00244	0.624
LIG_14-3-3_CanoR_1	245	249	PF00244	0.575
LIG_14-3-3_CanoR_1	284	289	PF00244	0.475
LIG_14-3-3_CanoR_1	355	359	PF00244	0.721
LIG_14-3-3_CanoR_1	444	450	PF00244	0.676
LIG_14-3-3_CanoR_1	45	54	PF00244	0.621
LIG_14-3-3_CanoR_1	505	514	PF00244	0.651
LIG_14-3-3_CanoR_1	537	543	PF00244	0.572
LIG_14-3-3_CanoR_1	546	556	PF00244	0.566
LIG_14-3-3_CanoR_1	73	79	PF00244	0.640
LIG_14-3-3_CanoR_1	747	756	PF00244	0.708
LIG_14-3-3_CanoR_1	757	767	PF00244	0.728
LIG_Actin_WH2_2	442	459	PF00022	0.611
LIG_Actin_WH2_2	528	545	PF00022	0.566
LIG_BIR_II_1	1	5	PF00653	0.723
LIG_BIR_III_2	3	7	PF00653	0.585
LIG_BIR_III_3	1	5	PF00653	0.661
LIG_BRCT_BRCA1_1	166	170	PF00533	0.485
LIG_BRCT_BRCA1_1	429	433	PF00533	0.646
LIG_CaM_IQ_9	174	189	PF13499	0.600
LIG_FHA_1	144	150	PF00498	0.587
LIG_FHA_1	328	334	PF00498	0.593
LIG_FHA_1	408	414	PF00498	0.748
LIG_FHA_1	520	526	PF00498	0.666
LIG_FHA_1	548	554	PF00498	0.668
LIG_FHA_1	565	571	PF00498	0.403
LIG_FHA_1	722	728	PF00498	0.644
LIG_FHA_1	749	755	PF00498	0.792
LIG_FHA_1	760	766	PF00498	0.598
LIG_FHA_1	828	834	PF00498	0.693
LIG_FHA_2	159	165	PF00498	0.606
LIG_FHA_2	223	229	PF00498	0.643
LIG_FHA_2	245	251	PF00498	0.601
LIG_FHA_2	311	317	PF00498	0.608
LIG_FHA_2	457	463	PF00498	0.482
LIG_FHA_2	661	667	PF00498	0.617
LIG_FHA_2	759	765	PF00498	0.738
LIG_LIR_Gen_1	167	177	PF02991	0.567
LIG_LIR_Gen_1	403	413	PF02991	0.552
LIG_LIR_Gen_1	573	581	PF02991	0.544
LIG_LIR_Gen_1	772	780	PF02991	0.558
LIG_LIR_Gen_1	793	802	PF02991	0.599
LIG_LIR_Nem_3	167	173	PF02991	0.533
LIG_LIR_Nem_3	573	578	PF02991	0.631
LIG_LIR_Nem_3	772	777	PF02991	0.682
LIG_LIR_Nem_3	793	799	PF02991	0.601
LIG_MYND_3	777	781	PF01753	0.685
LIG_RPA_C_Fungi	219	231	PF08784	0.476
LIG_SH2_CRK	774	778	PF00017	0.563
LIG_SH2_NCK_1	786	790	PF00017	0.577
LIG_SH2_STAP1	405	409	PF00017	0.557
LIG_SH2_STAP1	470	474	PF00017	0.653
LIG_SH2_STAT3	120	123	PF00017	0.662
LIG_SH2_STAT3	470	473	PF00017	0.652
LIG_SH2_STAT5	203	206	PF00017	0.647
LIG_SH3_3	362	368	PF00018	0.681
LIG_Sin3_3	682	689	PF02671	0.717
LIG_SUMO_SIM_anti_2	761	769	PF11976	0.676
LIG_SUMO_SIM_par_1	53	58	PF11976	0.542
LIG_SUMO_SIM_par_1	61	67	PF11976	0.569
LIG_TRAF2_1	138	141	PF00917	0.679
LIG_TRAF2_1	24	27	PF00917	0.693
LIG_TRAF2_1	247	250	PF00917	0.597
LIG_TRAF2_1	370	373	PF00917	0.709
LIG_TRAF2_1	818	821	PF00917	0.765
LIG_TRAF2_1	90	93	PF00917	0.509
LIG_WRC_WIRS_1	833	838	PF05994	0.572
MOD_CDK_SPK_2	752	757	PF00069	0.601
MOD_CK1_1	165	171	PF00069	0.649
MOD_CK1_1	357	363	PF00069	0.693
MOD_CK1_1	401	407	PF00069	0.650
MOD_CK1_1	427	433	PF00069	0.690
MOD_CK1_1	445	451	PF00069	0.523
MOD_CK1_1	452	458	PF00069	0.627
MOD_CK1_1	48	54	PF00069	0.579
MOD_CK1_1	541	547	PF00069	0.565
MOD_CK1_1	643	649	PF00069	0.654
MOD_CK1_1	726	732	PF00069	0.719
MOD_CK1_1	740	746	PF00069	0.760
MOD_CK1_1	772	778	PF00069	0.662
MOD_CK1_1	792	798	PF00069	0.775
MOD_CK1_1	827	833	PF00069	0.754
MOD_CK2_1	165	171	PF00069	0.588
MOD_CK2_1	222	228	PF00069	0.610
MOD_CK2_1	244	250	PF00069	0.635
MOD_CK2_1	284	290	PF00069	0.585
MOD_CK2_1	38	44	PF00069	0.577
MOD_CK2_1	66	72	PF00069	0.559
MOD_Cter_Amidation	745	748	PF01082	0.620
MOD_GlcNHglycan	205	208	PF01048	0.646
MOD_GlcNHglycan	253	256	PF01048	0.575
MOD_GlcNHglycan	6	9	PF01048	0.694
MOD_GlcNHglycan	670	673	PF01048	0.798
MOD_GlcNHglycan	804	807	PF01048	0.609
MOD_GlcNHglycan	809	813	PF01048	0.650
MOD_GSK3_1	158	165	PF00069	0.613
MOD_GSK3_1	186	193	PF00069	0.564
MOD_GSK3_1	34	41	PF00069	0.677
MOD_GSK3_1	357	364	PF00069	0.758
MOD_GSK3_1	4	11	PF00069	0.768
MOD_GSK3_1	424	431	PF00069	0.679
MOD_GSK3_1	445	452	PF00069	0.660
MOD_GSK3_1	501	508	PF00069	0.597
MOD_GSK3_1	541	548	PF00069	0.613
MOD_GSK3_1	552	559	PF00069	0.513
MOD_GSK3_1	636	643	PF00069	0.693
MOD_GSK3_1	654	661	PF00069	0.672
MOD_GSK3_1	666	673	PF00069	0.709
MOD_GSK3_1	717	724	PF00069	0.662
MOD_GSK3_1	733	740	PF00069	0.836
MOD_GSK3_1	748	755	PF00069	0.833
MOD_GSK3_1	772	779	PF00069	0.647
MOD_GSK3_1	790	797	PF00069	0.632
MOD_GSK3_1	824	831	PF00069	0.711
MOD_GSK3_1	839	846	PF00069	0.718
MOD_N-GLC_1	216	221	PF02516	0.542
MOD_N-GLC_1	526	531	PF02516	0.614
MOD_NEK2_1	190	195	PF00069	0.631
MOD_NEK2_1	196	201	PF00069	0.663
MOD_NEK2_1	256	261	PF00069	0.668
MOD_NEK2_1	34	39	PF00069	0.570
MOD_NEK2_1	389	394	PF00069	0.697
MOD_NEK2_1	429	434	PF00069	0.570
MOD_NEK2_1	456	461	PF00069	0.580
MOD_NEK2_1	634	639	PF00069	0.695
MOD_NEK2_2	104	109	PF00069	0.619
MOD_NEK2_2	538	543	PF00069	0.667
MOD_PIKK_1	158	164	PF00454	0.572
MOD_PIKK_1	310	316	PF00454	0.608
MOD_PIKK_1	34	40	PF00454	0.600
MOD_PIKK_1	359	365	PF00454	0.796
MOD_PIKK_1	476	482	PF00454	0.584
MOD_PIKK_1	48	54	PF00454	0.528
MOD_PIKK_1	509	515	PF00454	0.676
MOD_PIKK_1	658	664	PF00454	0.697
MOD_PIKK_1	740	746	PF00454	0.779
MOD_PK_1	582	588	PF00069	0.567
MOD_PKA_1	186	192	PF00069	0.609
MOD_PKA_1	737	743	PF00069	0.613
MOD_PKA_2	158	164	PF00069	0.634
MOD_PKA_2	186	192	PF00069	0.609
MOD_PKA_2	244	250	PF00069	0.571
MOD_PKA_2	354	360	PF00069	0.643
MOD_PKA_2	452	458	PF00069	0.665
MOD_PKA_2	476	482	PF00069	0.647
MOD_PKA_2	545	551	PF00069	0.569
MOD_PKA_2	643	649	PF00069	0.599
MOD_PKA_2	732	738	PF00069	0.719
MOD_PKA_2	9	15	PF00069	0.700
MOD_Plk_1	165	171	PF00069	0.649
MOD_Plk_1	197	203	PF00069	0.589
MOD_Plk_1	582	588	PF00069	0.592
MOD_Plk_2-3	832	838	PF00069	0.624
MOD_Plk_2-3	839	845	PF00069	0.638
MOD_Plk_4	165	171	PF00069	0.698
MOD_Plk_4	50	56	PF00069	0.602
MOD_Plk_4	723	729	PF00069	0.799
MOD_Plk_4	772	778	PF00069	0.662
MOD_Plk_4	839	845	PF00069	0.735
MOD_ProDKin_1	361	367	PF00069	0.696
MOD_ProDKin_1	424	430	PF00069	0.757
MOD_ProDKin_1	675	681	PF00069	0.780
MOD_ProDKin_1	707	713	PF00069	0.779
MOD_ProDKin_1	717	723	PF00069	0.651
MOD_ProDKin_1	752	758	PF00069	0.803
MOD_ProDKin_1	769	775	PF00069	0.590
MOD_ProDKin_1	843	849	PF00069	0.607
MOD_SUMO_for_1	395	398	PF00179	0.727
MOD_SUMO_rev_2	458	466	PF00179	0.721
MOD_SUMO_rev_2	486	491	PF00179	0.591
TRG_AP2beta_CARGO_1	573	582	PF09066	0.618
TRG_DiLeu_BaLyEn_6	299	304	PF01217	0.531
TRG_DiLeu_BaLyEn_6	566	571	PF01217	0.530
TRG_DiLeu_BaLyEn_6	644	649	PF01217	0.726
TRG_ENDOCYTIC_2	405	408	PF00928	0.558
TRG_ENDOCYTIC_2	774	777	PF00928	0.690
TRG_ER_diArg_1	186	188	PF00400	0.614
TRG_ER_diArg_1	230	233	PF00400	0.650
TRG_ER_diArg_1	274	277	PF00400	0.524
TRG_ER_diArg_1	336	339	PF00400	0.611
TRG_ER_diArg_1	383	386	PF00400	0.724
TRG_ER_diArg_1	530	532	PF00400	0.573
TRG_ER_diArg_1	614	616	PF00400	0.580
TRG_ER_diArg_1	618	621	PF00400	0.546
TRG_NES_CRM1_1	568	583	PF08389	0.617
TRG_NLS_Bipartite_1	614	632	PF00514	0.409
TRG_NLS_MonoExtC_3	618	624	PF00514	0.643
TRG_NLS_MonoExtC_3	693	698	PF00514	0.594
TRG_NLS_MonoExtN_4	182	189	PF00514	0.605
TRG_NLS_MonoExtN_4	691	698	PF00514	0.593
TRG_Pf-PMV_PEXEL_1	186	191	PF00026	0.578
TRG_Pf-PMV_PEXEL_1	194	198	PF00026	0.647
TRG_Pf-PMV_PEXEL_1	224	228	PF00026	0.566
TRG_Pf-PMV_PEXEL_1	302	306	PF00026	0.639
TRG_Pf-PMV_PEXEL_1	45	49	PF00026	0.569
TRG_Pf-PMV_PEXEL_1	569	573	PF00026	0.548
TRG_Pf-PMV_PEXEL_1	705	709	PF00026	0.608

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFI1	Leptomonas seymouri	36%	88%
A0A3S7XC59	Leishmania donovani	87%	100%
A4HQB9	Leishmania braziliensis	59%	100%
A4IE13	Leishmania infantum	87%	100%
E9AU35	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	85%