LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q0F9_LEIMA
TriTrypDb:
LmjF.36.6010 , LMJLV39_360072900 * , LMJSD75_360072900
Length:
670

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q0F9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q0F9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 261 265 PF00656 0.604
CLV_C14_Caspase3-7 496 500 PF00656 0.697
CLV_C14_Caspase3-7 65 69 PF00656 0.718
CLV_NRD_NRD_1 133 135 PF00675 0.554
CLV_NRD_NRD_1 14 16 PF00675 0.704
CLV_NRD_NRD_1 173 175 PF00675 0.484
CLV_NRD_NRD_1 21 23 PF00675 0.671
CLV_NRD_NRD_1 329 331 PF00675 0.566
CLV_NRD_NRD_1 375 377 PF00675 0.604
CLV_NRD_NRD_1 466 468 PF00675 0.730
CLV_NRD_NRD_1 506 508 PF00675 0.555
CLV_PCSK_KEX2_1 133 135 PF00082 0.554
CLV_PCSK_KEX2_1 164 166 PF00082 0.556
CLV_PCSK_KEX2_1 173 175 PF00082 0.448
CLV_PCSK_KEX2_1 21 23 PF00082 0.682
CLV_PCSK_KEX2_1 329 331 PF00082 0.566
CLV_PCSK_KEX2_1 375 377 PF00082 0.629
CLV_PCSK_KEX2_1 440 442 PF00082 0.636
CLV_PCSK_KEX2_1 466 468 PF00082 0.730
CLV_PCSK_KEX2_1 506 508 PF00082 0.555
CLV_PCSK_KEX2_1 595 597 PF00082 0.528
CLV_PCSK_KEX2_1 616 618 PF00082 0.495
CLV_PCSK_PC1ET2_1 164 166 PF00082 0.551
CLV_PCSK_PC1ET2_1 440 442 PF00082 0.614
CLV_PCSK_PC1ET2_1 595 597 PF00082 0.528
CLV_PCSK_PC1ET2_1 616 618 PF00082 0.495
CLV_PCSK_PC7_1 325 331 PF00082 0.532
CLV_PCSK_SKI1_1 233 237 PF00082 0.532
CLV_PCSK_SKI1_1 253 257 PF00082 0.307
CLV_PCSK_SKI1_1 269 273 PF00082 0.458
CLV_PCSK_SKI1_1 330 334 PF00082 0.538
CLV_PCSK_SKI1_1 36 40 PF00082 0.627
CLV_PCSK_SKI1_1 411 415 PF00082 0.666
DEG_APCC_DBOX_1 546 554 PF00400 0.547
DEG_APCC_DBOX_1 660 668 PF00400 0.648
DEG_Nend_UBRbox_3 1 3 PF02207 0.675
DEG_SPOP_SBC_1 458 462 PF00917 0.749
DOC_ANK_TNKS_1 404 411 PF00023 0.532
DOC_ANK_TNKS_1 466 473 PF00023 0.556
DOC_CKS1_1 56 61 PF01111 0.756
DOC_CYCLIN_yClb5_NLxxxL_5 36 42 PF00134 0.587
DOC_MAPK_DCC_7 642 651 PF00069 0.569
DOC_MAPK_gen_1 21 28 PF00069 0.559
DOC_MAPK_gen_1 329 335 PF00069 0.539
DOC_MAPK_gen_1 607 615 PF00069 0.489
DOC_MAPK_MEF2A_6 607 615 PF00069 0.489
DOC_MAPK_RevD_3 362 376 PF00069 0.655
DOC_PP4_FxxP_1 56 59 PF00568 0.818
DOC_PP4_FxxP_1 561 564 PF00568 0.654
DOC_USP7_MATH_1 29 33 PF00917 0.523
DOC_USP7_MATH_1 317 321 PF00917 0.524
DOC_USP7_MATH_1 351 355 PF00917 0.536
DOC_USP7_MATH_1 457 461 PF00917 0.786
DOC_USP7_MATH_1 500 504 PF00917 0.654
DOC_USP7_MATH_1 530 534 PF00917 0.704
DOC_USP7_MATH_1 581 585 PF00917 0.673
DOC_USP7_MATH_1 74 78 PF00917 0.595
DOC_USP7_MATH_1 96 100 PF00917 0.622
DOC_USP7_UBL2_3 436 440 PF12436 0.608
DOC_WW_Pin1_4 105 110 PF00397 0.775
DOC_WW_Pin1_4 21 26 PF00397 0.797
DOC_WW_Pin1_4 392 397 PF00397 0.606
DOC_WW_Pin1_4 416 421 PF00397 0.761
DOC_WW_Pin1_4 479 484 PF00397 0.636
DOC_WW_Pin1_4 48 53 PF00397 0.698
DOC_WW_Pin1_4 498 503 PF00397 0.692
DOC_WW_Pin1_4 535 540 PF00397 0.657
DOC_WW_Pin1_4 55 60 PF00397 0.665
DOC_WW_Pin1_4 577 582 PF00397 0.666
DOC_WW_Pin1_4 72 77 PF00397 0.753
LIG_14-3-3_CanoR_1 133 137 PF00244 0.580
LIG_14-3-3_CanoR_1 274 282 PF00244 0.573
LIG_14-3-3_CanoR_1 36 44 PF00244 0.554
LIG_14-3-3_CanoR_1 411 420 PF00244 0.769
LIG_14-3-3_CanoR_1 424 431 PF00244 0.525
LIG_14-3-3_CanoR_1 506 514 PF00244 0.670
LIG_14-3-3_CanoR_1 518 526 PF00244 0.572
LIG_Actin_WH2_2 490 508 PF00022 0.703
LIG_Actin_WH2_2 590 605 PF00022 0.552
LIG_BIR_III_2 499 503 PF00653 0.686
LIG_BRCT_BRCA1_1 52 56 PF00533 0.723
LIG_BRCT_BRCA1_1 662 666 PF00533 0.665
LIG_Clathr_ClatBox_1 403 407 PF01394 0.660
LIG_EH1_1 397 405 PF00400 0.696
LIG_eIF4E_1 510 516 PF01652 0.537
LIG_FHA_1 202 208 PF00498 0.632
LIG_FHA_1 210 216 PF00498 0.576
LIG_FHA_1 217 223 PF00498 0.464
LIG_FHA_1 37 43 PF00498 0.593
LIG_FHA_1 413 419 PF00498 0.566
LIG_FHA_1 448 454 PF00498 0.667
LIG_FHA_1 472 478 PF00498 0.794
LIG_FHA_1 56 62 PF00498 0.486
LIG_FHA_2 133 139 PF00498 0.553
LIG_FHA_2 146 152 PF00498 0.560
LIG_FHA_2 154 160 PF00498 0.534
LIG_FHA_2 259 265 PF00498 0.534
LIG_FHA_2 289 295 PF00498 0.428
LIG_FHA_2 494 500 PF00498 0.701
LIG_FHA_2 536 542 PF00498 0.727
LIG_FHA_2 550 556 PF00498 0.542
LIG_FHA_2 588 594 PF00498 0.515
LIG_LIR_Apic_2 508 513 PF02991 0.581
LIG_LIR_Apic_2 53 59 PF02991 0.802
LIG_LIR_Apic_2 554 560 PF02991 0.695
LIG_LIR_Gen_1 224 235 PF02991 0.542
LIG_LIR_Gen_1 358 367 PF02991 0.625
LIG_LIR_Gen_1 590 599 PF02991 0.513
LIG_LIR_Nem_3 252 257 PF02991 0.483
LIG_LIR_Nem_3 358 364 PF02991 0.621
LIG_LIR_Nem_3 577 582 PF02991 0.644
LIG_LIR_Nem_3 590 594 PF02991 0.315
LIG_PCNA_TLS_4 353 360 PF02747 0.516
LIG_SH2_CRK 254 258 PF00017 0.511
LIG_SH2_CRK 510 514 PF00017 0.535
LIG_SH2_CRK 557 561 PF00017 0.699
LIG_SH2_STAP1 203 207 PF00017 0.557
LIG_SH2_STAP1 303 307 PF00017 0.533
LIG_SH2_STAT5 203 206 PF00017 0.544
LIG_SH2_STAT5 504 507 PF00017 0.652
LIG_SH3_1 583 589 PF00018 0.563
LIG_SH3_3 403 409 PF00018 0.534
LIG_SH3_3 465 471 PF00018 0.646
LIG_SH3_3 492 498 PF00018 0.729
LIG_SH3_3 583 589 PF00018 0.555
LIG_SUMO_SIM_anti_2 68 75 PF11976 0.811
LIG_SUMO_SIM_par_1 24 30 PF11976 0.628
LIG_SUMO_SIM_par_1 493 499 PF11976 0.659
LIG_TRAF2_1 135 138 PF00917 0.538
LIG_TRAF2_1 169 172 PF00917 0.504
LIG_TRAF2_1 194 197 PF00917 0.550
LIG_TRAF2_1 363 366 PF00917 0.520
LIG_TRAF2_1 539 542 PF00917 0.553
LIG_WRC_WIRS_1 356 361 PF05994 0.620
MOD_CDC14_SPxK_1 580 583 PF00782 0.649
MOD_CDK_SPxK_1 577 583 PF00069 0.666
MOD_CK1_1 103 109 PF00069 0.787
MOD_CK1_1 17 23 PF00069 0.711
MOD_CK1_1 423 429 PF00069 0.577
MOD_CK1_1 447 453 PF00069 0.730
MOD_CK1_1 460 466 PF00069 0.654
MOD_CK1_1 482 488 PF00069 0.682
MOD_CK1_1 633 639 PF00069 0.636
MOD_CK1_1 654 660 PF00069 0.763
MOD_CK1_1 89 95 PF00069 0.711
MOD_CK2_1 132 138 PF00069 0.553
MOD_CK2_1 153 159 PF00069 0.619
MOD_CK2_1 29 35 PF00069 0.709
MOD_CK2_1 351 357 PF00069 0.466
MOD_CK2_1 535 541 PF00069 0.713
MOD_GlcNHglycan 111 115 PF01048 0.714
MOD_GlcNHglycan 154 159 PF01048 0.660
MOD_GlcNHglycan 264 268 PF01048 0.509
MOD_GlcNHglycan 343 346 PF01048 0.638
MOD_GlcNHglycan 486 489 PF01048 0.672
MOD_GlcNHglycan 532 535 PF01048 0.707
MOD_GlcNHglycan 91 94 PF01048 0.763
MOD_GlcNHglycan 98 101 PF01048 0.758
MOD_GSK3_1 17 24 PF00069 0.768
MOD_GSK3_1 351 358 PF00069 0.587
MOD_GSK3_1 392 399 PF00069 0.628
MOD_GSK3_1 412 419 PF00069 0.560
MOD_GSK3_1 420 427 PF00069 0.564
MOD_GSK3_1 47 54 PF00069 0.672
MOD_GSK3_1 577 584 PF00069 0.675
MOD_GSK3_1 72 79 PF00069 0.670
MOD_GSK3_1 84 91 PF00069 0.746
MOD_GSK3_1 96 103 PF00069 0.706
MOD_N-GLC_1 36 41 PF02516 0.635
MOD_N-GLC_1 381 386 PF02516 0.594
MOD_NEK2_1 132 137 PF00069 0.555
MOD_NEK2_1 185 190 PF00069 0.613
MOD_NEK2_1 199 204 PF00069 0.603
MOD_NEK2_1 263 268 PF00069 0.604
MOD_NEK2_1 272 277 PF00069 0.554
MOD_NEK2_1 380 385 PF00069 0.587
MOD_NEK2_1 414 419 PF00069 0.682
MOD_NEK2_1 422 427 PF00069 0.720
MOD_NEK2_1 86 91 PF00069 0.775
MOD_PIKK_1 216 222 PF00454 0.619
MOD_PIKK_1 274 280 PF00454 0.480
MOD_PIKK_1 36 42 PF00454 0.548
MOD_PK_1 642 648 PF00069 0.525
MOD_PKA_1 15 21 PF00069 0.794
MOD_PKA_2 132 138 PF00069 0.553
MOD_PKA_2 14 20 PF00069 0.556
MOD_PKA_2 423 429 PF00069 0.627
MOD_PKA_2 447 453 PF00069 0.602
MOD_PKA_2 505 511 PF00069 0.787
MOD_PKA_2 517 523 PF00069 0.613
MOD_PKA_2 660 666 PF00069 0.651
MOD_Plk_1 238 244 PF00069 0.634
MOD_Plk_1 29 35 PF00069 0.700
MOD_Plk_4 355 361 PF00069 0.567
MOD_Plk_4 399 405 PF00069 0.721
MOD_Plk_4 500 506 PF00069 0.693
MOD_Plk_4 662 668 PF00069 0.661
MOD_ProDKin_1 105 111 PF00069 0.774
MOD_ProDKin_1 21 27 PF00069 0.792
MOD_ProDKin_1 392 398 PF00069 0.606
MOD_ProDKin_1 416 422 PF00069 0.760
MOD_ProDKin_1 479 485 PF00069 0.634
MOD_ProDKin_1 48 54 PF00069 0.704
MOD_ProDKin_1 498 504 PF00069 0.690
MOD_ProDKin_1 535 541 PF00069 0.656
MOD_ProDKin_1 55 61 PF00069 0.665
MOD_ProDKin_1 577 583 PF00069 0.661
MOD_ProDKin_1 72 78 PF00069 0.753
MOD_SUMO_rev_2 157 166 PF00179 0.554
MOD_SUMO_rev_2 302 307 PF00179 0.533
TRG_DiLeu_BaEn_1 252 257 PF01217 0.558
TRG_ENDOCYTIC_2 247 250 PF00928 0.483
TRG_ENDOCYTIC_2 254 257 PF00928 0.457
TRG_ENDOCYTIC_2 361 364 PF00928 0.517
TRG_ER_diArg_1 132 134 PF00400 0.553
TRG_ER_diArg_1 189 192 PF00400 0.582
TRG_ER_diArg_1 466 468 PF00400 0.660
TRG_ER_diArg_1 505 507 PF00400 0.551
TRG_NLS_MonoExtC_3 615 621 PF00514 0.561
TRG_Pf-PMV_PEXEL_1 248 252 PF00026 0.501
TRG_Pf-PMV_PEXEL_1 274 278 PF00026 0.557
TRG_Pf-PMV_PEXEL_1 337 341 PF00026 0.495
TRG_Pf-PMV_PEXEL_1 36 40 PF00026 0.621

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IMK1 Leptomonas seymouri 45% 100%
A0A3S7XC33 Leishmania donovani 86% 100%
A4HQC0 Leishmania braziliensis 60% 98%
A4IE14 Leishmania infantum 86% 100%
E9AU36 Leishmania mexicana (strain MHOM/GT/2001/U1103) 82% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS