Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q0B1_LEIMA

TriTrypDb:

LmjF.36.6465 , LMJLV39_360078900 , LMJSD75_360078700

Length:

462

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q0B1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q0B1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	23	27	PF00656	0.497
CLV_C14_Caspase3-7	253	257	PF00656	0.643
CLV_C14_Caspase3-7	348	352	PF00656	0.661
CLV_C14_Caspase3-7	98	102	PF00656	0.585
CLV_NRD_NRD_1	216	218	PF00675	0.593
CLV_NRD_NRD_1	297	299	PF00675	0.614
CLV_NRD_NRD_1	344	346	PF00675	0.608
CLV_NRD_NRD_1	402	404	PF00675	0.725
CLV_NRD_NRD_1	408	410	PF00675	0.651
CLV_NRD_NRD_1	70	72	PF00675	0.541
CLV_PCSK_KEX2_1	296	298	PF00082	0.622
CLV_PCSK_KEX2_1	344	346	PF00082	0.608
CLV_PCSK_KEX2_1	401	403	PF00082	0.743
CLV_PCSK_KEX2_1	408	410	PF00082	0.642
CLV_PCSK_KEX2_1	85	87	PF00082	0.611
CLV_PCSK_PC1ET2_1	85	87	PF00082	0.611
CLV_PCSK_SKI1_1	165	169	PF00082	0.586
CLV_PCSK_SKI1_1	217	221	PF00082	0.659
CLV_PCSK_SKI1_1	233	237	PF00082	0.663
CLV_PCSK_SKI1_1	380	384	PF00082	0.587
DEG_SCF_SKP2-CKS1_1	114	121	PF00560	0.451
DEG_SPOP_SBC_1	169	173	PF00917	0.625
DOC_CKS1_1	154	159	PF01111	0.658
DOC_CKS1_1	330	335	PF01111	0.580
DOC_MAPK_gen_1	231	239	PF00069	0.614
DOC_MAPK_gen_1	391	399	PF00069	0.559
DOC_MAPK_MEF2A_6	231	239	PF00069	0.614
DOC_PP2B_LxvP_1	235	238	PF13499	0.698
DOC_USP7_MATH_1	170	174	PF00917	0.645
DOC_USP7_MATH_1	197	201	PF00917	0.706
DOC_USP7_MATH_1	223	227	PF00917	0.689
DOC_USP7_MATH_1	273	277	PF00917	0.720
DOC_USP7_MATH_1	280	284	PF00917	0.639
DOC_USP7_MATH_1	285	289	PF00917	0.581
DOC_USP7_MATH_1	305	309	PF00917	0.504
DOC_USP7_UBL2_3	46	50	PF12436	0.371
DOC_WW_Pin1_4	115	120	PF00397	0.480
DOC_WW_Pin1_4	153	158	PF00397	0.575
DOC_WW_Pin1_4	172	177	PF00397	0.508
DOC_WW_Pin1_4	192	197	PF00397	0.528
DOC_WW_Pin1_4	274	279	PF00397	0.719
DOC_WW_Pin1_4	323	328	PF00397	0.671
DOC_WW_Pin1_4	329	334	PF00397	0.624
DOC_WW_Pin1_4	363	368	PF00397	0.609
DOC_WW_Pin1_4	437	442	PF00397	0.658
DOC_WW_Pin1_4	5	10	PF00397	0.649
LIG_14-3-3_CanoR_1	165	174	PF00244	0.612
LIG_14-3-3_CanoR_1	242	248	PF00244	0.568
LIG_14-3-3_CanoR_1	29	37	PF00244	0.429
LIG_14-3-3_CanoR_1	296	302	PF00244	0.623
LIG_14-3-3_CanoR_1	319	324	PF00244	0.659
LIG_14-3-3_CanoR_1	380	388	PF00244	0.633
LIG_14-3-3_CanoR_1	401	410	PF00244	0.677
LIG_14-3-3_CanoR_1	74	78	PF00244	0.512
LIG_BIR_II_1	1	5	PF00653	0.623
LIG_BRCT_BRCA1_1	285	289	PF00533	0.684
LIG_BRCT_BRCA1_1	373	377	PF00533	0.635
LIG_FHA_1	154	160	PF00498	0.609
LIG_FHA_1	234	240	PF00498	0.698
LIG_FHA_1	290	296	PF00498	0.673
LIG_FHA_1	87	93	PF00498	0.581
LIG_FHA_2	21	27	PF00498	0.599
LIG_FHA_2	263	269	PF00498	0.672
LIG_FHA_2	346	352	PF00498	0.670
LIG_FHA_2	412	418	PF00498	0.590
LIG_FHA_2	74	80	PF00498	0.595
LIG_PCNA_yPIPBox_3	29	37	PF02747	0.512
LIG_Pex14_2	289	293	PF04695	0.631
LIG_SH2_STAT3	66	69	PF00017	0.527
LIG_SH3_2	334	339	PF14604	0.583
LIG_SH3_3	184	190	PF00018	0.663
LIG_SH3_3	327	333	PF00018	0.649
LIG_SH3_3	4	10	PF00018	0.787
LIG_TRAF2_1	404	407	PF00917	0.649
LIG_WRC_WIRS_1	33	38	PF05994	0.505
MOD_CDC14_SPxK_1	440	443	PF00782	0.653
MOD_CDK_SPK_2	323	328	PF00069	0.671
MOD_CDK_SPxK_1	115	121	PF00069	0.453
MOD_CDK_SPxK_1	437	443	PF00069	0.658
MOD_CDK_SPxxK_3	437	444	PF00069	0.658
MOD_CK1_1	150	156	PF00069	0.531
MOD_CK1_1	20	26	PF00069	0.742
MOD_CK1_1	226	232	PF00069	0.560
MOD_CK1_1	243	249	PF00069	0.640
MOD_CK1_1	252	258	PF00069	0.665
MOD_CK1_1	276	282	PF00069	0.690
MOD_CK1_1	283	289	PF00069	0.636
MOD_CK1_1	306	312	PF00069	0.653
MOD_CK1_1	322	328	PF00069	0.557
MOD_CK1_1	329	335	PF00069	0.619
MOD_CK1_1	347	353	PF00069	0.661
MOD_CK1_1	366	372	PF00069	0.617
MOD_CK1_1	386	392	PF00069	0.689
MOD_CK1_1	413	419	PF00069	0.720
MOD_CK1_1	452	458	PF00069	0.631
MOD_CK2_1	262	268	PF00069	0.673
MOD_CK2_1	28	34	PF00069	0.487
MOD_CK2_1	401	407	PF00069	0.699
MOD_CK2_1	411	417	PF00069	0.629
MOD_CK2_1	73	79	PF00069	0.550
MOD_GlcNHglycan	150	153	PF01048	0.715
MOD_GlcNHglycan	160	163	PF01048	0.615
MOD_GlcNHglycan	19	22	PF01048	0.635
MOD_GlcNHglycan	2	5	PF01048	0.658
MOD_GlcNHglycan	203	206	PF01048	0.698
MOD_GlcNHglycan	23	26	PF01048	0.624
MOD_GlcNHglycan	247	250	PF01048	0.673
MOD_GlcNHglycan	271	274	PF01048	0.695
MOD_GlcNHglycan	289	292	PF01048	0.505
MOD_GlcNHglycan	305	308	PF01048	0.530
MOD_GlcNHglycan	429	432	PF01048	0.638
MOD_GlcNHglycan	452	455	PF01048	0.622
MOD_GlcNHglycan	89	92	PF01048	0.580
MOD_GSK3_1	165	172	PF00069	0.647
MOD_GSK3_1	17	24	PF00069	0.808
MOD_GSK3_1	192	199	PF00069	0.694
MOD_GSK3_1	245	252	PF00069	0.693
MOD_GSK3_1	257	264	PF00069	0.606
MOD_GSK3_1	269	276	PF00069	0.583
MOD_GSK3_1	279	286	PF00069	0.610
MOD_GSK3_1	28	35	PF00069	0.466
MOD_GSK3_1	303	310	PF00069	0.665
MOD_GSK3_1	313	320	PF00069	0.632
MOD_GSK3_1	322	329	PF00069	0.560
MOD_GSK3_1	335	342	PF00069	0.583
MOD_GSK3_1	343	350	PF00069	0.621
MOD_GSK3_1	363	370	PF00069	0.569
MOD_GSK3_1	376	383	PF00069	0.570
MOD_GSK3_1	409	416	PF00069	0.631
MOD_GSK3_1	433	440	PF00069	0.692
MOD_GSK3_1	449	456	PF00069	0.513
MOD_GSK3_1	61	68	PF00069	0.502
MOD_GSK3_1	73	80	PF00069	0.416
MOD_LATS_1	378	384	PF00433	0.628
MOD_N-GLC_1	243	248	PF02516	0.726
MOD_NEK2_1	17	22	PF00069	0.614
MOD_NEK2_1	245	250	PF00069	0.669
MOD_NEK2_1	261	266	PF00069	0.590
MOD_NEK2_1	289	294	PF00069	0.669
MOD_NEK2_1	313	318	PF00069	0.741
MOD_NEK2_1	376	381	PF00069	0.579
MOD_NEK2_1	410	415	PF00069	0.655
MOD_PIKK_1	150	156	PF00454	0.625
MOD_PIKK_1	226	232	PF00454	0.560
MOD_PIKK_1	28	34	PF00454	0.443
MOD_PIKK_1	280	286	PF00454	0.657
MOD_PIKK_1	332	338	PF00454	0.575
MOD_PIKK_1	339	345	PF00454	0.610
MOD_PIKK_1	402	408	PF00454	0.654
MOD_PIKK_1	424	430	PF00454	0.634
MOD_PIKK_1	433	439	PF00454	0.642
MOD_PIKK_1	65	71	PF00454	0.533
MOD_PK_1	297	303	PF00069	0.632
MOD_PKA_1	297	303	PF00069	0.676
MOD_PKA_1	344	350	PF00069	0.591
MOD_PKA_1	401	407	PF00069	0.699
MOD_PKA_1	443	449	PF00069	0.690
MOD_PKA_2	28	34	PF00069	0.443
MOD_PKA_2	297	303	PF00069	0.676
MOD_PKA_2	338	344	PF00069	0.648
MOD_PKA_2	401	407	PF00069	0.724
MOD_PKA_2	73	79	PF00069	0.541
MOD_Plk_1	233	239	PF00069	0.587
MOD_Plk_1	243	249	PF00069	0.773
MOD_Plk_4	257	263	PF00069	0.667
MOD_Plk_4	289	295	PF00069	0.663
MOD_Plk_4	32	38	PF00069	0.543
MOD_Plk_4	371	377	PF00069	0.552
MOD_Plk_4	456	462	PF00069	0.660
MOD_ProDKin_1	115	121	PF00069	0.481
MOD_ProDKin_1	153	159	PF00069	0.575
MOD_ProDKin_1	172	178	PF00069	0.508
MOD_ProDKin_1	192	198	PF00069	0.532
MOD_ProDKin_1	274	280	PF00069	0.719
MOD_ProDKin_1	323	329	PF00069	0.671
MOD_ProDKin_1	363	369	PF00069	0.610
MOD_ProDKin_1	437	443	PF00069	0.658
MOD_ProDKin_1	5	11	PF00069	0.649
MOD_SUMO_for_1	219	222	PF00179	0.572
MOD_SUMO_rev_2	355	363	PF00179	0.665
TRG_ER_diArg_1	214	217	PF00400	0.565
TRG_ER_diArg_1	295	298	PF00400	0.680
TRG_ER_diArg_1	401	403	PF00400	0.639
TRG_ER_diArg_1	408	410	PF00400	0.639
TRG_NLS_MonoExtC_3	216	222	PF00514	0.568
TRG_NLS_MonoExtN_4	214	221	PF00514	0.655
TRG_Pf-PMV_PEXEL_1	131	136	PF00026	0.565

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8ILD3	Leishmania donovani	85%	99%
A4HQG7	Leishmania braziliensis	56%	100%
A4ICA3	Leishmania infantum	85%	99%