SAS-6_N domain-containing protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q091_LEIMA

TriTrypDb:

LmjF.36.6640 , LMJLV39_360081000 , LMJSD75_360080900

Length:

197

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	11
GO:0043226	organelle	2	11
GO:0043229	intracellular organelle	3	11
GO:0110165	cellular anatomical entity	1	11

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Expansion

Sequence features

Q4Q091

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q091

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	21	25	PF00656	0.475
CLV_PCSK_KEX2_1	190	192	PF00082	0.612
CLV_PCSK_PC1ET2_1	190	192	PF00082	0.612
CLV_PCSK_SKI1_1	57	61	PF00082	0.499
CLV_Separin_Metazoa	165	169	PF03568	0.474
DEG_APCC_DBOX_1	178	186	PF00400	0.454
DOC_CYCLIN_yCln2_LP_2	155	161	PF00134	0.529
DOC_MAPK_HePTP_8	147	159	PF00069	0.529
DOC_MAPK_MEF2A_6	150	159	PF00069	0.516
DOC_MAPK_MEF2A_6	65	74	PF00069	0.559

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I7A5	Leptomonas seymouri	96%	100%
A0A0S4IMA0	Bodo saltans	56%	98%
A0A1X0NLJ6	Trypanosomatidae	71%	98%
A0A3Q8IQ43	Leishmania donovani	100%	100%
A0A3R7NPT4	Trypanosoma rangeli	69%	98%
A4HQI7	Leishmania braziliensis	97%	100%
D0A3N5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	65%	86%
E9AHZ6	Leishmania infantum	100%	100%
E9AUA0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%

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