Cytochrome b5 heme-binding domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

cytochrome b5-like Heme/Steroid binding domain containing protein, putative

Species:

Leishmania major

UniProt:

Q4Q088_LEIMA

TriTrypDb:

LmjF.36.6670 , LMJLV39_360081500 , LMJSD75_360081400

Length:

146


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0012505	endomembrane system	2	2
GO:0016020	membrane	2	4
GO:0110165	cellular anatomical entity	1	4

Q4Q088

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q088


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	19	23	PF00656	0.541
CLV_C14_Caspase3-7	63	67	PF00656	0.203
CLV_NRD_NRD_1	9	11	PF00675	0.698
CLV_PCSK_KEX2_1	9	11	PF00082	0.604
CLV_PCSK_SKI1_1	142	146	PF00082	0.598
DOC_PP4_FxxP_1	70	73	PF00568	0.329
DOC_USP7_MATH_1	16	20	PF00917	0.501
DOC_USP7_MATH_1	73	77	PF00917	0.415
DOC_USP7_MATH_2	31	37	PF00917	0.492
DOC_USP7_UBL2_3	120	124	PF12436	0.361
DOC_WW_Pin1_4	104	109	PF00397	0.291
DOC_WW_Pin1_4	48	53	PF00397	0.291
LIG_14-3-3_CanoR_1	140	145	PF00244	0.409
LIG_14-3-3_CanoR_1	24	34	PF00244	0.663
LIG_BIR_II_1	1	5	PF00653	0.530
LIG_deltaCOP1_diTrp_1	115	121	PF00928	0.332
LIG_FHA_2	36	42	PF00498	0.358
LIG_LIR_Gen_1	51	62	PF02991	0.337
LIG_LIR_Gen_1	76	85	PF02991	0.415
LIG_LIR_Nem_3	122	128	PF02991	0.384
LIG_LIR_Nem_3	2	6	PF02991	0.523
LIG_LIR_Nem_3	51	57	PF02991	0.368
LIG_LIR_Nem_3	76	80	PF02991	0.363
LIG_LYPXL_yS_3	125	128	PF13949	0.335
LIG_Pex14_1	117	121	PF04695	0.270
LIG_RPA_C_Fungi	5	17	PF08784	0.444
LIG_SH2_CRK	54	58	PF00017	0.409
LIG_SH2_STAP1	77	81	PF00017	0.400
LIG_SH2_STAT3	138	141	PF00017	0.515
LIG_TRAF2_1	133	136	PF00917	0.418
LIG_TRAF2_1	95	98	PF00917	0.361
LIG_WRC_WIRS_1	128	133	PF05994	0.378
LIG_WRC_WIRS_1	34	39	PF05994	0.449
MOD_CK1_1	2	8	PF00069	0.616
MOD_CK2_1	110	116	PF00069	0.338
MOD_CK2_1	35	41	PF00069	0.369
MOD_CK2_1	92	98	PF00069	0.341
MOD_CMANNOS	4	7	PF00535	0.506
MOD_N-GLC_1	48	53	PF02516	0.291
MOD_PKA_2	23	29	PF00069	0.450
MOD_PKA_2	8	14	PF00069	0.529
MOD_Plk_4	127	133	PF00069	0.266
MOD_ProDKin_1	104	110	PF00069	0.291
MOD_ProDKin_1	48	54	PF00069	0.291
MOD_SUMO_rev_2	116	126	PF00179	0.508
MOD_SUMO_rev_2	8	16	PF00179	0.649
TRG_ENDOCYTIC_2	125	128	PF00928	0.335
TRG_ENDOCYTIC_2	54	57	PF00928	0.283
TRG_ENDOCYTIC_2	77	80	PF00928	0.304


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8C7	Leptomonas seymouri	68%	99%
A0A0N1I427	Leptomonas seymouri	38%	78%
A0A0S4IM89	Bodo saltans	55%	100%
A0A0S4IWT4	Bodo saltans	39%	85%
A0A0S4KHZ8	Bodo saltans	41%	95%
A0A1X0NM31	Trypanosomatidae	53%	100%
A0A1X0NTL9	Trypanosomatidae	33%	92%
A0A1X0P9U9	Trypanosomatidae	38%	87%
A0A3Q8IGX1	Leishmania donovani	92%	100%
A0A3R7L838	Trypanosoma rangeli	62%	100%
A0A3R7RC54	Trypanosoma rangeli	49%	81%
A0A3S7X865	Leishmania donovani	40%	82%
A0A422NSD0	Trypanosoma rangeli	31%	100%
A4HB24	Leishmania braziliensis	35%	82%
A4HQJ0	Leishmania braziliensis	79%	99%
A4IA81	Leishmania infantum	40%	82%
C9ZM28	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	95%
C9ZNV9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	92%
E9AHZ9	Leishmania infantum	92%	100%
E9AUA3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
E9B594	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	82%
O00264	Homo sapiens	36%	75%
O13995	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	88%
O55022	Mus musculus	36%	75%
P70580	Rattus norvegicus	36%	75%
Q12091	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	39%	96%
Q17QC0	Bos taurus	37%	75%
Q1JQA5	Bos taurus	38%	86%
Q4Q2N9	Leishmania major	40%	82%
Q5RED0	Pongo abelii	36%	75%
Q5XIU9	Rattus norvegicus	32%	67%
Q5ZKN2	Gallus gallus	33%	76%
Q6IUR5	Rattus norvegicus	38%	85%
Q7YZW5	Caenorhabditis elegans	30%	80%
Q80UU9	Mus musculus	32%	67%
Q95250	Sus scrofa	36%	75%
Q9CQ45	Mus musculus	39%	85%
Q9SK39	Arabidopsis thaliana	44%	100%
Q9UMX5	Homo sapiens	38%	85%
Q9XFM6	Arabidopsis thaliana	42%	66%
V5DM24	Trypanosoma cruzi	47%	82%