LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q087_LEIMA
TriTrypDb:
LmjF.36.6680 , LMJLV39_360081600 , LMJSD75_360081500
Length:
162

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q087
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q087

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 121 123 PF00675 0.526
CLV_NRD_NRD_1 157 159 PF00675 0.522
CLV_NRD_NRD_1 18 20 PF00675 0.598
CLV_NRD_NRD_1 56 58 PF00675 0.506
CLV_NRD_NRD_1 93 95 PF00675 0.514
CLV_PCSK_KEX2_1 121 123 PF00082 0.549
CLV_PCSK_KEX2_1 157 159 PF00082 0.639
CLV_PCSK_KEX2_1 56 58 PF00082 0.524
CLV_PCSK_KEX2_1 93 95 PF00082 0.514
CLV_PCSK_SKI1_1 158 162 PF00082 0.585
CLV_PCSK_SKI1_1 4 8 PF00082 0.675
CLV_PCSK_SKI1_1 77 81 PF00082 0.525
DOC_MAPK_gen_1 19 25 PF00069 0.565
DOC_MAPK_MEF2A_6 70 78 PF00069 0.535
DOC_PP1_RVXF_1 141 148 PF00149 0.564
DOC_WW_Pin1_4 8 13 PF00397 0.654
LIG_14-3-3_CterR_2 157 162 PF00244 0.556
LIG_EVH1_2 2 6 PF00568 0.772
LIG_FHA_1 59 65 PF00498 0.567
LIG_FHA_1 73 79 PF00498 0.493
LIG_FHA_1 82 88 PF00498 0.530
LIG_FHA_2 98 104 PF00498 0.580
LIG_SUMO_SIM_anti_2 21 27 PF11976 0.483
LIG_SUMO_SIM_par_1 34 42 PF11976 0.510
LIG_TRAF2_1 11 14 PF00917 0.618
MOD_CK1_1 38 44 PF00069 0.509
MOD_CK1_1 8 14 PF00069 0.612
MOD_CK1_1 81 87 PF00069 0.425
MOD_CK2_1 8 14 PF00069 0.634
MOD_CK2_1 97 103 PF00069 0.566
MOD_Cter_Amidation 119 122 PF01082 0.364
MOD_GSK3_1 58 65 PF00069 0.610
MOD_GSK3_1 77 84 PF00069 0.427
MOD_N-GLC_1 8 13 PF02516 0.639
MOD_NEK2_1 151 156 PF00069 0.549
MOD_NEK2_1 72 77 PF00069 0.484
MOD_NEK2_1 97 102 PF00069 0.630
MOD_PIKK_1 24 30 PF00454 0.537
MOD_PK_1 35 41 PF00069 0.517
MOD_Plk_1 72 78 PF00069 0.531
MOD_ProDKin_1 8 14 PF00069 0.648
TRG_DiLeu_BaEn_1 135 140 PF01217 0.552
TRG_DiLeu_BaEn_1 21 26 PF01217 0.379
TRG_ENDOCYTIC_2 159 162 PF00928 0.616
TRG_ER_diArg_1 157 159 PF00400 0.522
TRG_ER_diArg_1 56 58 PF00400 0.559
TRG_ER_diArg_1 93 95 PF00400 0.525
TRG_Pf-PMV_PEXEL_1 56 60 PF00026 0.520
TRG_Pf-PMV_PEXEL_1 93 98 PF00026 0.634

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IM37 Leptomonas seymouri 63% 99%
A0A1X0NL82 Trypanosomatidae 30% 100%
A0A3R7NY60 Trypanosoma rangeli 29% 100%
A0A3S7XCF7 Leishmania donovani 91% 100%
A4HQJ1 Leishmania braziliensis 80% 99%
E9AI00 Leishmania infantum 91% 100%
E9AUA4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
V5AXM4 Trypanosoma cruzi 26% 80%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS