Putative mitochondrial carrier protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

mitochondrial carrier protein, putative

Species:

Leishmania major

UniProt:

Q4Q083_LEIMA

TriTrypDb:

LmjF.36.6720 , LMJLV39_360082200 , LMJSD75_360082100

Length:

196

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4Q083

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q083

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	173	177	PF00082	0.492
CLV_PCSK_SKI1_1	71	75	PF00082	0.416
CLV_PCSK_SKI1_1	80	84	PF00082	0.437
DOC_CKS1_1	109	114	PF01111	0.497
DOC_CKS1_1	124	129	PF01111	0.298
DOC_CYCLIN_RxL_1	75	85	PF00134	0.332
DOC_CYCLIN_yCln2_LP_2	124	130	PF00134	0.382
DOC_MAPK_MEF2A_6	138	145	PF00069	0.437
DOC_MAPK_MEF2A_6	75	83	PF00069	0.290
DOC_PP1_RVXF_1	78	84	PF00149	0.290
DOC_USP7_MATH_1	2	6	PF00917	0.574
DOC_USP7_MATH_1	36	40	PF00917	0.290
DOC_WW_Pin1_4	108	113	PF00397	0.510
DOC_WW_Pin1_4	123	128	PF00397	0.304
DOC_WW_Pin1_4	176	181	PF00397	0.432
DOC_WW_Pin1_4	4	9	PF00397	0.548
DOC_WW_Pin1_4	75	80	PF00397	0.290
LIG_14-3-3_CanoR_1	117	127	PF00244	0.521
LIG_BIR_II_1	1	5	PF00653	0.581
LIG_BRCT_BRCA1_1	38	42	PF00533	0.290
LIG_FHA_1	123	129	PF00498	0.399
LIG_FHA_1	153	159	PF00498	0.464
LIG_FHA_1	177	183	PF00498	0.582
LIG_FHA_1	76	82	PF00498	0.290
LIG_FHA_2	62	68	PF00498	0.290
LIG_LIR_Gen_1	15	26	PF02991	0.414
LIG_LIR_Gen_1	39	49	PF02991	0.374
LIG_LIR_Nem_3	15	21	PF02991	0.412
LIG_LIR_Nem_3	170	175	PF02991	0.482
LIG_LIR_Nem_3	39	45	PF02991	0.290
LIG_PDZ_Class_1	191	196	PF00595	0.466
LIG_PTB_Apo_2	48	55	PF02174	0.290
LIG_REV1ctd_RIR_1	71	78	PF16727	0.290
LIG_SH2_CRK	172	176	PF00017	0.454
LIG_SH2_STAT5	129	132	PF00017	0.598
LIG_SH2_STAT5	178	181	PF00017	0.444
LIG_SH2_STAT5	18	21	PF00017	0.411
LIG_SH2_STAT5	192	195	PF00017	0.479
LIG_SH3_3	106	112	PF00018	0.519
LIG_SH3_3	153	159	PF00018	0.487
LIG_WRC_WIRS_1	83	88	PF05994	0.290
MOD_CDK_SPK_2	75	80	PF00069	0.290
MOD_CK1_1	56	62	PF00069	0.290
MOD_CMANNOS	62	65	PF00535	0.290
MOD_GlcNHglycan	120	123	PF01048	0.431
MOD_GlcNHglycan	4	7	PF01048	0.561
MOD_GSK3_1	111	118	PF00069	0.573
MOD_GSK3_1	90	97	PF00069	0.308
MOD_N-GLC_1	94	99	PF02516	0.290
MOD_NEK2_1	1	6	PF00069	0.578
MOD_NEK2_1	115	120	PF00069	0.632
MOD_NEK2_1	191	196	PF00069	0.466
MOD_NEK2_1	82	87	PF00069	0.395
MOD_NEK2_1	94	99	PF00069	0.409
MOD_NEK2_2	41	46	PF00069	0.290
MOD_Plk_1	151	157	PF00069	0.512
MOD_Plk_1	94	100	PF00069	0.311
MOD_Plk_4	111	117	PF00069	0.401
MOD_Plk_4	178	184	PF00069	0.426
MOD_Plk_4	97	103	PF00069	0.290
MOD_ProDKin_1	108	114	PF00069	0.501
MOD_ProDKin_1	123	129	PF00069	0.300
MOD_ProDKin_1	176	182	PF00069	0.429
MOD_ProDKin_1	4	10	PF00069	0.538
MOD_ProDKin_1	75	81	PF00069	0.290
TRG_DiLeu_BaLyEn_6	77	82	PF01217	0.290
TRG_ENDOCYTIC_2	172	175	PF00928	0.449
TRG_ENDOCYTIC_2	18	21	PF00928	0.411

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7Y4	Leptomonas seymouri	27%	67%
A0A0N1I6I9	Leptomonas seymouri	25%	68%
A0A1X0NJD2	Trypanosomatidae	27%	69%
A0A3R7KLL6	Trypanosoma rangeli	25%	68%
A0A3R7RT89	Trypanosoma rangeli	28%	67%
A0A3S7X2U2	Leishmania donovani	26%	67%
A4I4Z5	Leishmania infantum	26%	67%
A4QNX2	Danio rerio	29%	68%
E9ALE6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	67%
Q1ECW7	Danio rerio	26%	67%
Q54FE6	Dictyostelium discoideum	32%	69%
Q54W11	Dictyostelium discoideum	33%	69%
Q8CFJ7	Mus musculus	31%	68%
Q8N413	Homo sapiens	31%	68%
V5BDR1	Trypanosoma cruzi	29%	66%