Elks delta-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

elks delta-like protein

Species:

Leishmania major

UniProt:

Q4Q057_LEIMA

TriTrypDb:

LmjF.36.6960 , LMJLV39_360085100 , LMJSD75_360084900

Length:

368

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q057

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q057

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	124	128	PF00656	0.525
CLV_C14_Caspase3-7	43	47	PF00656	0.490
CLV_NRD_NRD_1	103	105	PF00675	0.587
CLV_NRD_NRD_1	200	202	PF00675	0.516
CLV_NRD_NRD_1	205	207	PF00675	0.572
CLV_NRD_NRD_1	249	251	PF00675	0.600
CLV_NRD_NRD_1	304	306	PF00675	0.572
CLV_NRD_NRD_1	31	33	PF00675	0.567
CLV_NRD_NRD_1	332	334	PF00675	0.521
CLV_PCSK_KEX2_1	130	132	PF00082	0.502
CLV_PCSK_KEX2_1	200	202	PF00082	0.507
CLV_PCSK_KEX2_1	221	223	PF00082	0.567
CLV_PCSK_KEX2_1	304	306	PF00082	0.536
CLV_PCSK_KEX2_1	33	35	PF00082	0.608
CLV_PCSK_PC1ET2_1	130	132	PF00082	0.569
CLV_PCSK_PC1ET2_1	221	223	PF00082	0.379
CLV_PCSK_PC1ET2_1	33	35	PF00082	0.598
CLV_PCSK_SKI1_1	130	134	PF00082	0.422
CLV_PCSK_SKI1_1	207	211	PF00082	0.596
CLV_PCSK_SKI1_1	222	226	PF00082	0.459
CLV_PCSK_SKI1_1	250	254	PF00082	0.542
CLV_PCSK_SKI1_1	334	338	PF00082	0.517
CLV_PCSK_SKI1_1	351	355	PF00082	0.329
CLV_PCSK_SKI1_1	72	76	PF00082	0.578
DEG_APCC_DBOX_1	12	20	PF00400	0.573
DEG_APCC_KENBOX_2	347	351	PF00400	0.570
DOC_MAPK_gen_1	175	183	PF00069	0.572
DOC_MAPK_gen_1	221	227	PF00069	0.379
DOC_MAPK_gen_1	328	338	PF00069	0.463
DOC_MAPK_RevD_3	135	151	PF00069	0.605
DOC_PP1_RVXF_1	332	339	PF00149	0.554
DOC_USP7_MATH_1	155	159	PF00917	0.452
LIG_14-3-3_CanoR_1	131	135	PF00244	0.481
LIG_14-3-3_CanoR_1	136	141	PF00244	0.465
LIG_14-3-3_CanoR_1	211	216	PF00244	0.597
LIG_14-3-3_CanoR_1	250	257	PF00244	0.428
LIG_14-3-3_CanoR_1	58	65	PF00244	0.608
LIG_APCC_ABBA_1	213	218	PF00400	0.504
LIG_FHA_1	178	184	PF00498	0.563
LIG_FHA_1	208	214	PF00498	0.574
LIG_FHA_1	251	257	PF00498	0.572
LIG_FHA_1	277	283	PF00498	0.712
LIG_FHA_2	167	173	PF00498	0.597
LIG_FHA_2	282	288	PF00498	0.492
LIG_FHA_2	50	56	PF00498	0.624
LIG_NRBOX	143	149	PF00104	0.609
LIG_PCNA_yPIPBox_3	244	256	PF02747	0.556
LIG_PCNA_yPIPBox_3	39	49	PF02747	0.399
LIG_SH2_SRC	216	219	PF00017	0.613
LIG_SH2_STAT3	93	96	PF00017	0.613
LIG_SH2_STAT5	261	264	PF00017	0.615
LIG_SH2_STAT5	307	310	PF00017	0.551
LIG_SH2_STAT5	48	51	PF00017	0.646
LIG_SH2_STAT5	93	96	PF00017	0.508
LIG_SH3_3	149	155	PF00018	0.635
LIG_TRAF2_1	100	103	PF00917	0.545
LIG_TRAF2_1	169	172	PF00917	0.562
LIG_TRAF2_1	52	55	PF00917	0.556
LIG_UBA3_1	140	149	PF00899	0.566
LIG_UBA3_1	194	198	PF00899	0.463
MOD_CK1_1	158	164	PF00069	0.632
MOD_CK1_1	50	56	PF00069	0.609
MOD_CK1_1	57	63	PF00069	0.423
MOD_CK1_1	82	88	PF00069	0.688
MOD_CK2_1	153	159	PF00069	0.641
MOD_CK2_1	166	172	PF00069	0.458
MOD_CK2_1	182	188	PF00069	0.586
MOD_CK2_1	272	278	PF00069	0.720
MOD_CK2_1	281	287	PF00069	0.493
MOD_CK2_1	314	320	PF00069	0.495
MOD_CK2_1	49	55	PF00069	0.537
MOD_CK2_1	57	63	PF00069	0.517
MOD_GlcNHglycan	155	158	PF01048	0.681
MOD_GlcNHglycan	264	267	PF01048	0.611
MOD_GlcNHglycan	274	277	PF01048	0.630
MOD_GlcNHglycan	59	62	PF01048	0.423
MOD_GSK3_1	207	214	PF00069	0.623
MOD_GSK3_1	256	263	PF00069	0.547
MOD_GSK3_1	272	279	PF00069	0.692
MOD_GSK3_1	356	363	PF00069	0.468
MOD_GSK3_1	50	57	PF00069	0.587
MOD_GSK3_1	75	82	PF00069	0.624
MOD_N-GLC_1	211	216	PF02516	0.562
MOD_N-GLC_1	82	87	PF02516	0.484
MOD_NEK2_1	166	171	PF00069	0.579
MOD_NEK2_1	19	24	PF00069	0.508
MOD_NEK2_1	256	261	PF00069	0.521
MOD_NEK2_1	280	285	PF00069	0.655
MOD_NEK2_1	324	329	PF00069	0.555
MOD_NEK2_1	356	361	PF00069	0.457
MOD_NEK2_1	49	54	PF00069	0.626
MOD_PIKK_1	50	56	PF00454	0.634
MOD_PIKK_1	77	83	PF00454	0.668
MOD_PIKK_1	92	98	PF00454	0.611
MOD_PKA_1	130	136	PF00069	0.531
MOD_PKA_1	250	256	PF00069	0.427
MOD_PKA_2	130	136	PF00069	0.494
MOD_PKA_2	269	275	PF00069	0.709
MOD_PKA_2	327	333	PF00069	0.563
MOD_PKA_2	57	63	PF00069	0.560
MOD_PKB_1	175	183	PF00069	0.554
MOD_PKB_1	32	40	PF00069	0.599
MOD_Plk_1	177	183	PF00069	0.545
MOD_Plk_1	19	25	PF00069	0.486
MOD_Plk_1	211	217	PF00069	0.529
MOD_Plk_1	319	325	PF00069	0.615
MOD_Plk_1	340	346	PF00069	0.560
MOD_Plk_1	82	88	PF00069	0.482
MOD_Plk_2-3	190	196	PF00069	0.526
MOD_Plk_4	136	142	PF00069	0.510
MOD_Plk_4	143	149	PF00069	0.554
MOD_Plk_4	19	25	PF00069	0.542
MOD_Plk_4	190	196	PF00069	0.526
MOD_Plk_4	211	217	PF00069	0.531
MOD_Plk_4	319	325	PF00069	0.589
MOD_Plk_4	82	88	PF00069	0.665
MOD_SUMO_for_1	309	312	PF00179	0.613
MOD_SUMO_rev_2	101	107	PF00179	0.558
MOD_SUMO_rev_2	120	126	PF00179	0.488
MOD_SUMO_rev_2	254	262	PF00179	0.529
MOD_SUMO_rev_2	347	356	PF00179	0.571
TRG_DiLeu_BaEn_1	190	195	PF01217	0.494
TRG_DiLeu_BaEn_1	234	239	PF01217	0.584
TRG_DiLeu_BaEn_4	240	246	PF01217	0.481
TRG_ER_diArg_1	200	202	PF00400	0.566
TRG_ER_diArg_1	304	306	PF00400	0.582
TRG_NES_CRM1_1	15	28	PF08389	0.601
TRG_NES_CRM1_1	203	218	PF08389	0.575
TRG_Pf-PMV_PEXEL_1	119	123	PF00026	0.607
TRG_Pf-PMV_PEXEL_1	200	204	PF00026	0.530
TRG_Pf-PMV_PEXEL_1	250	254	PF00026	0.550

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IAJ8	Leptomonas seymouri	66%	100%
A0A0S4KNY7	Bodo saltans	24%	95%
A0A1X0NLT9	Trypanosomatidae	33%	98%
A0A3Q8IQ67	Leishmania donovani	92%	100%
A0A422NVX8	Trypanosoma rangeli	32%	98%
A4HQL8	Leishmania braziliensis	74%	100%
A4ICD6	Leishmania infantum	92%	100%
D0A3S1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	98%
E9AUD3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
V5BD37	Trypanosoma cruzi	31%	99%