PSP1 C-terminal domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

PSP1 C-terminal conserved region, putative

Species:

Leishmania major

UniProt:

Q4Q051_LEIMA

TriTrypDb:

LmjF.36.7000 , LMJLV39_360085800 , LMJSD75_360085600

Length:

241

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 19
NetGPI	no	yes: 0, no: 19

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	3
GO:0110165	cellular anatomical entity	1	3

Expansion

Sequence features

Q4Q051

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q051

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	168	172	PF00656	0.418
CLV_PCSK_SKI1_1	155	159	PF00082	0.316
CLV_PCSK_SKI1_1	203	207	PF00082	0.291
DEG_Nend_Nbox_1	1	3	PF02207	0.578
DEG_SCF_FBW7_1	11	18	PF00400	0.450
DOC_CKS1_1	12	17	PF01111	0.449
DOC_MAPK_gen_1	20	28	PF00069	0.527
DOC_MAPK_gen_1	212	220	PF00069	0.290
DOC_MAPK_MEF2A_6	125	133	PF00069	0.382
DOC_PP1_RVXF_1	201	208	PF00149	0.237
DOC_PP1_RVXF_1	212	218	PF00149	0.237
DOC_PP1_SILK_1	151	156	PF00149	0.334
DOC_USP7_MATH_1	149	153	PF00917	0.468
DOC_WW_Pin1_4	11	16	PF00397	0.518
DOC_WW_Pin1_4	81	86	PF00397	0.495
LIG_14-3-3_CanoR_1	155	164	PF00244	0.300
LIG_14-3-3_CanoR_1	37	41	PF00244	0.585
LIG_FHA_1	145	151	PF00498	0.577
LIG_FHA_2	140	146	PF00498	0.484
LIG_FHA_2	156	162	PF00498	0.256
LIG_FHA_2	2	8	PF00498	0.685
LIG_FHA_2	211	217	PF00498	0.308
LIG_IBAR_NPY_1	44	46	PF08397	0.553
LIG_LIR_Gen_1	216	225	PF02991	0.323
LIG_LIR_Nem_3	192	198	PF02991	0.421
LIG_LIR_Nem_3	216	220	PF02991	0.264
LIG_LIR_Nem_3	223	228	PF02991	0.273
LIG_SH2_PTP2	118	121	PF00017	0.302
LIG_SH2_STAT5	118	121	PF00017	0.322
LIG_SH2_STAT5	143	146	PF00017	0.456
LIG_SH3_3	27	33	PF00018	0.531
LIG_SH3_3	82	88	PF00018	0.595
MOD_CK1_1	139	145	PF00069	0.530
MOD_CK2_1	106	112	PF00069	0.359
MOD_CK2_1	139	145	PF00069	0.461
MOD_CK2_1	155	161	PF00069	0.300
MOD_GSK3_1	11	18	PF00069	0.675
MOD_GSK3_1	89	96	PF00069	0.561
MOD_NEK2_1	1	6	PF00069	0.628
MOD_PIKK_1	155	161	PF00454	0.246
MOD_PKA_1	203	209	PF00069	0.288
MOD_PKA_2	36	42	PF00069	0.606
MOD_Plk_4	139	145	PF00069	0.442
MOD_Plk_4	149	155	PF00069	0.318
MOD_Plk_4	203	209	PF00069	0.268
MOD_Plk_4	93	99	PF00069	0.530
MOD_ProDKin_1	11	17	PF00069	0.521
MOD_ProDKin_1	81	87	PF00069	0.493
MOD_SUMO_rev_2	163	172	PF00179	0.369
MOD_SUMO_rev_2	197	205	PF00179	0.244
TRG_ENDOCYTIC_2	118	121	PF00928	0.303
TRG_ER_diArg_1	212	215	PF00400	0.418

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8D9	Leptomonas seymouri	75%	100%
A0A0S4JV55	Bodo saltans	38%	72%
A0A0S4KL40	Bodo saltans	56%	100%
A0A1X0NLP9	Trypanosomatidae	62%	100%
A0A1X0NWX9	Trypanosomatidae	42%	80%
A0A3Q8IC14	Leishmania donovani	32%	67%
A0A3Q8ILM8	Leishmania donovani	89%	100%
A0A3R7M5V2	Trypanosoma rangeli	61%	100%
A0A3S5ISC8	Trypanosoma rangeli	36%	80%
A4HGI7	Leishmania braziliensis	86%	100%
A4HUB9	Leishmania infantum	32%	67%
A4ICE2	Leishmania infantum	90%	100%
D0A3S8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	56%	100%
D0A7N8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	77%
E9AN18	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	67%
E9AUD9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
Q4QHK8	Leishmania major	32%	67%
V5BB20	Trypanosoma cruzi	40%	80%