Augmin complex subunit msd5

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

Q25302_LEIIN

TriTrypDb:

LINF_350056300

Length:

171

Annotations

Annotations by Jardim et al.

Membrane associated proteins, ORF10

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	1
GO:0005930	axoneme	2	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

Q25302

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q25302

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	130	134	PF00082	0.482
CLV_PCSK_SKI1_1	141	145	PF00082	0.417
CLV_PCSK_SKI1_1	85	89	PF00082	0.527
CLV_Separin_Metazoa	164	168	PF03568	0.385
CLV_Separin_Metazoa	41	45	PF03568	0.458
DEG_APCC_DBOX_1	100	108	PF00400	0.497
DEG_APCC_DBOX_1	38	46	PF00400	0.447
DOC_MAPK_gen_1	130	139	PF00069	0.537
DOC_MAPK_gen_1	37	45	PF00069	0.460
DOC_MAPK_MEF2A_6	162	170	PF00069	0.482
DOC_PP1_RVXF_1	165	171	PF00149	0.443
DOC_PP4_FxxP_1	4	7	PF00568	0.417
LIG_14-3-3_CanoR_1	141	150	PF00244	0.421
LIG_14-3-3_CanoR_1	167	171	PF00244	0.504
LIG_14-3-3_CanoR_1	72	78	PF00244	0.498
LIG_14-3-3_CanoR_1	9	14	PF00244	0.526
LIG_Actin_WH2_2	10	28	PF00022	0.588
LIG_APCC_ABBA_1	43	48	PF00400	0.520
LIG_BIR_II_1	1	5	PF00653	0.505
LIG_FHA_1	72	78	PF00498	0.503
LIG_FHA_1	89	95	PF00498	0.292
LIG_FHA_2	22	28	PF00498	0.575
LIG_LIR_Apic_2	2	7	PF02991	0.444
LIG_LIR_Gen_1	75	86	PF02991	0.414
LIG_LIR_Nem_3	75	81	PF02991	0.431
LIG_LIR_Nem_3	83	87	PF02991	0.494
LIG_PDZ_Class_1	166	171	PF00595	0.497
LIG_SH2_CRK	84	88	PF00017	0.570
LIG_SH2_STAP1	31	35	PF00017	0.547
LIG_SH2_STAT3	46	49	PF00017	0.553
MOD_CK1_1	110	116	PF00069	0.622
MOD_CK1_1	12	18	PF00069	0.496
MOD_CK1_1	53	59	PF00069	0.575
MOD_CK1_1	71	77	PF00069	0.410
MOD_CK2_1	21	27	PF00069	0.556
MOD_GlcNHglycan	109	112	PF01048	0.578
MOD_GSK3_1	137	144	PF00069	0.400
MOD_GSK3_1	151	158	PF00069	0.515
MOD_GSK3_1	67	74	PF00069	0.458
MOD_NEK2_1	107	112	PF00069	0.600
MOD_NEK2_1	11	16	PF00069	0.490
MOD_PIKK_1	110	116	PF00454	0.598
MOD_PIKK_1	151	157	PF00454	0.517
MOD_PK_1	9	15	PF00069	0.600
MOD_PKA_2	71	77	PF00069	0.462
MOD_Plk_1	56	62	PF00069	0.509
MOD_Plk_4	12	18	PF00069	0.531
MOD_Plk_4	132	138	PF00069	0.484
MOD_SUMO_for_1	161	164	PF00179	0.411
MOD_SUMO_for_1	20	23	PF00179	0.539
MOD_SUMO_rev_2	113	122	PF00179	0.431
TRG_DiLeu_BaEn_1	103	108	PF01217	0.537
TRG_ENDOCYTIC_2	84	87	PF00928	0.535
TRG_Pf-PMV_PEXEL_1	96	100	PF00026	0.567

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IHH3	Leptomonas seymouri	52%	100%
A0A0S4JTH6	Bodo saltans	25%	97%
A0A1X0P528	Trypanosomatidae	28%	100%
A0A422NCM8	Trypanosoma rangeli	28%	100%
A4HNH0	Leishmania braziliensis	70%	100%
C9ZYE2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	100%
E9AFY1	Leishmania major	95%	100%
E9B734	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%