LeishMANIAdb
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Hydrophilic surface protein 2

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hydrophilic surface protein 2
Gene product:
hydrophilic acylated surface protein a
Species:
Leishmania major
UniProt:
P90552_LEIMA
TriTrypDb:
LmjF.23.1088 , LMJLV39_230019600 , LMJSD75_230019800
Length:
73

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 2
Forrest at al. (procyclic) no yes: 2
Silverman et al. no yes: 0
Pissara et al. yes yes: 3
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

P90552
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: P90552

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 27 31 PF00656 0.777
CLV_C14_Caspase3-7 46 50 PF00656 0.649
DOC_USP7_MATH_1 13 17 PF00917 0.607
DOC_USP7_UBL2_3 7 11 PF12436 0.797
LIG_FHA_2 22 28 PF00498 0.736
MOD_CK1_1 3 9 PF00069 0.665
MOD_CK2_1 6 12 PF00069 0.684
MOD_GlcNHglycan 15 18 PF01048 0.573
MOD_GlcNHglycan 8 11 PF01048 0.647
MOD_GSK3_1 19 26 PF00069 0.665
MOD_NEK2_1 1 6 PF00069 0.749
MOD_NMyristoyl 1 7 PF02799 0.682

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7WXQ9 Leishmania donovani 72% 91%
A4I0F2 Leishmania infantum 71% 91%
E9AWB5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 62% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS