Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania major

UniProt:

O97195_LEIMA

TriTrypDb:

LmjF.04.1140 , LMJLV39_040017000 , LMJSD75_040017300

Length:

300

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

O97195

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: O97195

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	278	282	PF00656	0.607
CLV_C14_Caspase3-7	3	7	PF00656	0.567
CLV_NRD_NRD_1	193	195	PF00675	0.615
CLV_NRD_NRD_1	32	34	PF00675	0.726
CLV_PCSK_KEX2_1	14	16	PF00082	0.631
CLV_PCSK_KEX2_1	193	195	PF00082	0.607
CLV_PCSK_PC1ET2_1	14	16	PF00082	0.782
CLV_PCSK_SKI1_1	168	172	PF00082	0.616
CLV_PCSK_SKI1_1	181	185	PF00082	0.462
CLV_PCSK_SKI1_1	194	198	PF00082	0.481
DOC_PP2B_LxvP_1	116	119	PF13499	0.588
DOC_USP7_MATH_1	125	129	PF00917	0.754
DOC_USP7_MATH_1	141	145	PF00917	0.710
DOC_USP7_MATH_1	218	222	PF00917	0.625
DOC_USP7_MATH_1	232	236	PF00917	0.742
DOC_USP7_MATH_1	238	242	PF00917	0.716
DOC_USP7_MATH_1	272	276	PF00917	0.742
DOC_USP7_MATH_1	67	71	PF00917	0.759
DOC_USP7_MATH_1	72	76	PF00917	0.805
DOC_USP7_UBL2_3	34	38	PF12436	0.709
DOC_WW_Pin1_4	1	6	PF00397	0.696
DOC_WW_Pin1_4	102	107	PF00397	0.721
DOC_WW_Pin1_4	268	273	PF00397	0.814
LIG_14-3-3_CanoR_1	193	199	PF00244	0.618
LIG_14-3-3_CanoR_1	94	98	PF00244	0.768
LIG_14-3-3_CanoR_1	99	106	PF00244	0.800
LIG_AP2alpha_2	55	57	PF02296	0.656
LIG_BIR_II_1	1	5	PF00653	0.706
LIG_CtBP_PxDLS_1	213	217	PF00389	0.546
LIG_deltaCOP1_diTrp_1	55	60	PF00928	0.691
LIG_FHA_1	290	296	PF00498	0.701
LIG_FXI_DFP_1	57	61	PF00024	0.669
LIG_HCF-1_HBM_1	149	152	PF13415	0.552
LIG_LIR_Gen_1	55	62	PF02991	0.779
LIG_LIR_Nem_3	148	154	PF02991	0.705
LIG_LIR_Nem_3	55	60	PF02991	0.684
LIG_PTAP_UEV_1	254	259	PF05743	0.714
LIG_SH2_STAT5	152	155	PF00017	0.708
LIG_SH2_STAT5	21	24	PF00017	0.574
LIG_SH3_1	252	258	PF00018	0.754
LIG_SH3_3	2	8	PF00018	0.724
LIG_SH3_3	252	258	PF00018	0.824
LIG_SH3_3	266	272	PF00018	0.731
LIG_SH3_3	50	56	PF00018	0.672
LIG_SH3_4	34	41	PF00018	0.689
LIG_TRAF2_1	217	220	PF00917	0.696
LIG_WW_1	18	21	PF00397	0.592
LIG_WW_3	51	55	PF00397	0.770
MOD_CDK_SPK_2	268	273	PF00069	0.742
MOD_CDK_SPxxK_3	102	109	PF00069	0.781
MOD_CK1_1	105	111	PF00069	0.767
MOD_CK1_1	282	288	PF00069	0.696
MOD_CK1_1	98	104	PF00069	0.745
MOD_CK2_1	141	147	PF00069	0.734
MOD_CK2_1	159	165	PF00069	0.566
MOD_GlcNHglycan	113	116	PF01048	0.655
MOD_GlcNHglycan	161	164	PF01048	0.622
MOD_GlcNHglycan	219	223	PF01048	0.674
MOD_GlcNHglycan	232	235	PF01048	0.794
MOD_GlcNHglycan	255	258	PF01048	0.743
MOD_GlcNHglycan	70	73	PF01048	0.709
MOD_GlcNHglycan	74	77	PF01048	0.696
MOD_GlcNHglycan	91	94	PF01048	0.796
MOD_GSK3_1	105	112	PF00069	0.579
MOD_GSK3_1	123	130	PF00069	0.682
MOD_GSK3_1	238	245	PF00069	0.656
MOD_GSK3_1	268	275	PF00069	0.807
MOD_GSK3_1	279	286	PF00069	0.635
MOD_GSK3_1	68	75	PF00069	0.756
MOD_GSK3_1	89	96	PF00069	0.790
MOD_GSK3_1	97	104	PF00069	0.717
MOD_LATS_1	107	113	PF00433	0.747
MOD_LATS_1	27	33	PF00433	0.753
MOD_NEK2_1	279	284	PF00069	0.700
MOD_PIKK_1	125	131	PF00454	0.599
MOD_PIKK_1	184	190	PF00454	0.640
MOD_PIKK_1	74	80	PF00454	0.841
MOD_PK_1	109	115	PF00069	0.749
MOD_PKA_2	243	249	PF00069	0.711
MOD_PKA_2	272	278	PF00069	0.724
MOD_PKA_2	93	99	PF00069	0.766
MOD_Plk_1	238	244	PF00069	0.745
MOD_Plk_4	194	200	PF00069	0.610
MOD_ProDKin_1	1	7	PF00069	0.690
MOD_ProDKin_1	102	108	PF00069	0.721
MOD_ProDKin_1	268	274	PF00069	0.816
TRG_ENDOCYTIC_2	151	154	PF00928	0.706
TRG_ER_diArg_1	193	195	PF00400	0.622
TRG_ER_diArg_1	199	202	PF00400	0.599

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIT4	Leptomonas seymouri	37%	93%
A0A3S5H5F0	Leishmania donovani	90%	100%
A4H428	Leishmania braziliensis	58%	99%
A4HSB2	Leishmania infantum	90%	100%
E9AK95	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	84%