Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania major

UniProt:

O97006_LEIMA

TriTrypDb:

LmjF.04.0880 , LMJLV39_040014300 , LMJSD75_040014700

Length:

180

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

O97006

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: O97006

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	54	56	PF00675	0.672
CLV_PCSK_KEX2_1	54	56	PF00082	0.672
CLV_PCSK_SKI1_1	143	147	PF00082	0.701
DEG_Kelch_Keap1_1	158	163	PF01344	0.658
DEG_Nend_UBRbox_1	1	4	PF02207	0.663
DEG_SPOP_SBC_1	12	16	PF00917	0.656
DOC_ANK_TNKS_1	53	60	PF00023	0.586
DOC_MAPK_MEF2A_6	90	98	PF00069	0.550
DOC_USP7_MATH_1	12	16	PF00917	0.694
DOC_USP7_MATH_1	72	76	PF00917	0.646
DOC_WW_Pin1_4	1	6	PF00397	0.661
DOC_WW_Pin1_4	100	105	PF00397	0.568
DOC_WW_Pin1_4	107	112	PF00397	0.460
LIG_14-3-3_CanoR_1	13	18	PF00244	0.650
LIG_14-3-3_CanoR_1	137	142	PF00244	0.653
LIG_14-3-3_CanoR_1	143	150	PF00244	0.640
LIG_14-3-3_CanoR_1	79	84	PF00244	0.615
LIG_BRCT_BRCA1_1	101	105	PF00533	0.625
LIG_FHA_1	108	114	PF00498	0.590
LIG_FHA_1	12	18	PF00498	0.651
LIG_FHA_1	136	142	PF00498	0.667
LIG_FHA_1	144	150	PF00498	0.599
LIG_FHA_2	117	123	PF00498	0.630
LIG_FHA_2	142	148	PF00498	0.706
LIG_FHA_2	44	50	PF00498	0.659
LIG_KLC1_Yacidic_2	163	167	PF13176	0.552
LIG_LIR_Apic_2	80	86	PF02991	0.640
LIG_LIR_Nem_3	127	133	PF02991	0.687
LIG_SH2_CRK	130	134	PF00017	0.550
LIG_SH2_CRK	28	32	PF00017	0.807
LIG_SH2_NCK_1	28	32	PF00017	0.673
LIG_SH2_SRC	26	29	PF00017	0.610
LIG_SH2_STAP1	26	30	PF00017	0.635
LIG_SH2_STAT3	114	117	PF00017	0.578
LIG_SH2_STAT5	114	117	PF00017	0.578
LIG_SH2_STAT5	165	168	PF00017	0.554
LIG_SH3_1	2	8	PF00018	0.647
LIG_SH3_3	2	8	PF00018	0.647
LIG_SH3_3	98	104	PF00018	0.583
LIG_SH3_CIN85_PxpxPR_1	8	13	PF14604	0.568
LIG_SUMO_SIM_par_1	132	140	PF11976	0.671
LIG_TYR_ITSM	126	133	PF00017	0.692
MOD_CK1_1	174	180	PF00069	0.663
MOD_CK2_1	100	106	PF00069	0.549
MOD_CK2_1	141	147	PF00069	0.691
MOD_CK2_1	43	49	PF00069	0.670
MOD_CK2_1	79	85	PF00069	0.644
MOD_GlcNHglycan	36	39	PF01048	0.691
MOD_GSK3_1	112	119	PF00069	0.680
MOD_GSK3_1	132	139	PF00069	0.384
MOD_LATS_1	11	17	PF00433	0.653
MOD_N-GLC_1	117	122	PF02516	0.639
MOD_N-GLC_1	44	49	PF02516	0.575
MOD_N-GLC_1	77	82	PF02516	0.583
MOD_NEK2_2	132	137	PF00069	0.502
MOD_PK_1	13	19	PF00069	0.648
MOD_PKA_2	12	18	PF00069	0.651
MOD_PKA_2	136	142	PF00069	0.626
MOD_Plk_1	171	177	PF00069	0.663
MOD_Plk_1	77	83	PF00069	0.584
MOD_ProDKin_1	1	7	PF00069	0.658
MOD_ProDKin_1	100	106	PF00069	0.570
MOD_ProDKin_1	107	113	PF00069	0.454
TRG_ENDOCYTIC_2	130	133	PF00928	0.687
TRG_Pf-PMV_PEXEL_1	143	147	PF00026	0.566

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WNW2	Leishmania donovani	83%	100%
A4H3Z8	Leishmania braziliensis	62%	71%
A4HS89	Leishmania infantum	81%	100%