Bifunctional helicase and thymine dioxygenase JBP2

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

J Biosynthesis Protein 2

Species:

Leishmania major

UniProt:

JBP2_LEIMA

TriTrypDb:

LmjF.14.0040 , LMJLV39_140005400 , LMJSD75_140005400

Length:

1098

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	12
GO:0043226	organelle	2	12
GO:0043227	membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043231	intracellular membrane-bounded organelle	4	12
GO:0110165	cellular anatomical entity	1	12

Expansion

Sequence features

Q4QFY1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QFY1

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006259	DNA metabolic process	4	12
GO:0006281	DNA repair	5	2
GO:0006283	transcription-coupled nucleotide-excision repair	7	2
GO:0006289	nucleotide-excision repair	6	2
GO:0006304	DNA modification	5	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0006950	response to stress	2	2
GO:0006974	DNA damage response	4	2
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0033554	cellular response to stress	3	2
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0043170	macromolecule metabolic process	3	12
GO:0043412	macromolecule modification	4	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044260	obsolete cellular macromolecule metabolic process	3	12
GO:0046483	heterocycle metabolic process	3	12
GO:0050896	response to stimulus	1	2
GO:0051716	cellular response to stimulus	2	2
GO:0070580	base J metabolic process	6	12
GO:0071704	organic substance metabolic process	2	12
GO:0090304	nucleic acid metabolic process	4	12
GO:1901360	organic cyclic compound metabolic process	3	12

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003677	DNA binding	4	12
GO:0003678	DNA helicase activity	3	4
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	5
GO:0005488	binding	1	12
GO:0005506	iron ion binding	6	2
GO:0005524	ATP binding	5	12
GO:0008094	ATP-dependent activity, acting on DNA	2	12
GO:0008198	ferrous iron binding	7	2
GO:0016462	pyrophosphatase activity	5	4
GO:0016491	oxidoreductase activity	2	12
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	3	12
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	4	12
GO:0016787	hydrolase activity	2	5
GO:0016817	hydrolase activity, acting on acid anhydrides	3	4
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	4
GO:0016887	ATP hydrolysis activity	7	4
GO:0017076	purine nucleotide binding	4	12
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	4
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0043169	cation binding	3	12
GO:0046872	metal ion binding	4	12
GO:0046914	transition metal ion binding	5	2
GO:0050341	thymine dioxygenase activity	5	12
GO:0051213	dioxygenase activity	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140097	catalytic activity, acting on DNA	3	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:0140658	ATP-dependent chromatin remodeler activity	3	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	252	256	PF00656	0.589
CLV_C14_Caspase3-7	883	887	PF00656	0.425
CLV_NRD_NRD_1	1004	1006	PF00675	0.242
CLV_NRD_NRD_1	1007	1009	PF00675	0.389
CLV_NRD_NRD_1	1030	1032	PF00675	0.331
CLV_NRD_NRD_1	1065	1067	PF00675	0.379
CLV_NRD_NRD_1	355	357	PF00675	0.265
CLV_NRD_NRD_1	48	50	PF00675	0.512
CLV_NRD_NRD_1	499	501	PF00675	0.426
CLV_NRD_NRD_1	668	670	PF00675	0.300
CLV_NRD_NRD_1	907	909	PF00675	0.300
CLV_NRD_NRD_1	949	951	PF00675	0.233
CLV_PCSK_FUR_1	669	673	PF00082	0.278
CLV_PCSK_FUR_1	947	951	PF00082	0.298
CLV_PCSK_KEX2_1	1004	1006	PF00082	0.242
CLV_PCSK_KEX2_1	1065	1067	PF00082	0.370
CLV_PCSK_KEX2_1	355	357	PF00082	0.285
CLV_PCSK_KEX2_1	443	445	PF00082	0.246
CLV_PCSK_KEX2_1	48	50	PF00082	0.419
CLV_PCSK_KEX2_1	499	501	PF00082	0.423
CLV_PCSK_KEX2_1	668	670	PF00082	0.335
CLV_PCSK_KEX2_1	671	673	PF00082	0.335
CLV_PCSK_KEX2_1	738	740	PF00082	0.335
CLV_PCSK_KEX2_1	947	949	PF00082	0.235
CLV_PCSK_PC1ET2_1	443	445	PF00082	0.246
CLV_PCSK_PC1ET2_1	671	673	PF00082	0.246
CLV_PCSK_PC1ET2_1	738	740	PF00082	0.335
CLV_PCSK_SKI1_1	1009	1013	PF00082	0.443
CLV_PCSK_SKI1_1	1023	1027	PF00082	0.347
CLV_PCSK_SKI1_1	1032	1036	PF00082	0.297
CLV_PCSK_SKI1_1	1037	1041	PF00082	0.291
CLV_PCSK_SKI1_1	1046	1050	PF00082	0.386
CLV_PCSK_SKI1_1	1082	1086	PF00082	0.515
CLV_PCSK_SKI1_1	112	116	PF00082	0.565
CLV_PCSK_SKI1_1	443	447	PF00082	0.312
CLV_PCSK_SKI1_1	505	509	PF00082	0.454
CLV_PCSK_SKI1_1	668	672	PF00082	0.250
CLV_PCSK_SKI1_1	705	709	PF00082	0.252
CLV_PCSK_SKI1_1	927	931	PF00082	0.242
DEG_APCC_DBOX_1	421	429	PF00400	0.442
DEG_APCC_DBOX_1	499	507	PF00400	0.518
DEG_APCC_DBOX_1	700	708	PF00400	0.552
DEG_Nend_Nbox_1	1	3	PF02207	0.615
DEG_ODPH_VHL_1	378	390	PF01847	0.478
DEG_ODPH_VHL_1	543	555	PF01847	0.467
DEG_SPOP_SBC_1	8	12	PF00917	0.434
DOC_CKS1_1	596	601	PF01111	0.522
DOC_CYCLIN_RxL_1	109	119	PF00134	0.606
DOC_CYCLIN_RxL_1	120	129	PF00134	0.250
DOC_CYCLIN_yClb5_NLxxxL_5	701	708	PF00134	0.478
DOC_CYCLIN_yCln2_LP_2	114	120	PF00134	0.384
DOC_MAPK_DCC_7	538	548	PF00069	0.483
DOC_MAPK_gen_1	1004	1013	PF00069	0.607
DOC_MAPK_gen_1	443	453	PF00069	0.522
DOC_MAPK_gen_1	499	508	PF00069	0.496
DOC_MAPK_gen_1	649	657	PF00069	0.500
DOC_MAPK_gen_1	668	679	PF00069	0.374
DOC_MAPK_gen_1	699	708	PF00069	0.537
DOC_MAPK_gen_1	894	903	PF00069	0.494
DOC_MAPK_gen_1	908	915	PF00069	0.404
DOC_MAPK_HePTP_8	891	903	PF00069	0.411
DOC_MAPK_MEF2A_6	574	583	PF00069	0.431
DOC_MAPK_MEF2A_6	671	679	PF00069	0.475
DOC_MAPK_MEF2A_6	699	708	PF00069	0.478
DOC_MAPK_MEF2A_6	894	903	PF00069	0.456
DOC_MAPK_MEF2A_6	959	966	PF00069	0.487
DOC_MAPK_NFAT4_5	959	967	PF00069	0.522
DOC_MAPK_RevD_3	895	909	PF00069	0.474
DOC_PP1_RVXF_1	121	128	PF00149	0.455
DOC_PP1_RVXF_1	720	727	PF00149	0.442
DOC_PP1_RVXF_1	909	916	PF00149	0.431
DOC_PP2B_LxvP_1	319	322	PF13499	0.519
DOC_PP2B_LxvP_1	533	536	PF13499	0.350
DOC_PP4_FxxP_1	31	34	PF00568	0.398
DOC_USP7_MATH_1	172	176	PF00917	0.632
DOC_USP7_MATH_1	205	209	PF00917	0.721
DOC_USP7_MATH_1	256	260	PF00917	0.592
DOC_USP7_MATH_1	389	393	PF00917	0.478
DOC_USP7_MATH_1	526	530	PF00917	0.492
DOC_USP7_UBL2_3	369	373	PF12436	0.478
DOC_USP7_UBL2_3	443	447	PF12436	0.442
DOC_USP7_UBL2_3	645	649	PF12436	0.431
DOC_WW_Pin1_4	143	148	PF00397	0.560
DOC_WW_Pin1_4	149	154	PF00397	0.470
DOC_WW_Pin1_4	165	170	PF00397	0.613
DOC_WW_Pin1_4	174	179	PF00397	0.545
DOC_WW_Pin1_4	30	35	PF00397	0.382
DOC_WW_Pin1_4	595	600	PF00397	0.522
DOC_WW_Pin1_4	671	676	PF00397	0.478
DOC_WW_Pin1_4	708	713	PF00397	0.431
LIG_14-3-3_CanoR_1	1008	1014	PF00244	0.396
LIG_14-3-3_CanoR_1	1015	1024	PF00244	0.331
LIG_14-3-3_CanoR_1	198	204	PF00244	0.707
LIG_14-3-3_CanoR_1	479	483	PF00244	0.305
LIG_14-3-3_CanoR_1	517	522	PF00244	0.512
LIG_14-3-3_CanoR_1	538	546	PF00244	0.489
LIG_14-3-3_CanoR_1	7	17	PF00244	0.409
LIG_14-3-3_CanoR_1	80	87	PF00244	0.553
LIG_14-3-3_CanoR_1	859	868	PF00244	0.610
LIG_14-3-3_CanoR_1	927	934	PF00244	0.442
LIG_14-3-3_CanoR_1	93	97	PF00244	0.475
LIG_Actin_WH2_2	438	454	PF00022	0.510
LIG_Actin_WH2_2	690	707	PF00022	0.478
LIG_APCC_ABBA_1	183	188	PF00400	0.548
LIG_APCC_ABBA_1	67	72	PF00400	0.336
LIG_APCC_ABBAyCdc20_2	275	281	PF00400	0.466
LIG_APCC_ABBAyCdc20_2	411	417	PF00400	0.442
LIG_APCC_ABBAyCdc20_2	773	779	PF00400	0.535
LIG_BRCT_BRCA1_1	225	229	PF00533	0.689
LIG_BRCT_BRCA1_1	630	634	PF00533	0.442
LIG_BRCT_BRCA1_2	225	231	PF00533	0.580
LIG_deltaCOP1_diTrp_1	770	777	PF00928	0.431
LIG_eIF4E_1	485	491	PF01652	0.328
LIG_EVH1_2	736	740	PF00568	0.474
LIG_FHA_1	1028	1034	PF00498	0.381
LIG_FHA_1	1079	1085	PF00498	0.435
LIG_FHA_1	212	218	PF00498	0.549
LIG_FHA_1	329	335	PF00498	0.432
LIG_FHA_1	401	407	PF00498	0.431
LIG_FHA_1	466	472	PF00498	0.552
LIG_FHA_1	478	484	PF00498	0.371
LIG_FHA_1	518	524	PF00498	0.515
LIG_FHA_1	567	573	PF00498	0.442
LIG_FHA_1	672	678	PF00498	0.478
LIG_FHA_1	692	698	PF00498	0.531
LIG_FHA_1	868	874	PF00498	0.486
LIG_FHA_1	934	940	PF00498	0.478
LIG_FHA_2	242	248	PF00498	0.632
LIG_FHA_2	459	465	PF00498	0.393
LIG_FHA_2	8	14	PF00498	0.595
LIG_GBD_Chelix_1	482	490	PF00786	0.325
LIG_Integrin_RGD_1	418	420	PF01839	0.225
LIG_IRF3_LxIS_1	147	152	PF10401	0.508
LIG_LIR_Apic_2	584	590	PF02991	0.384
LIG_LIR_Apic_2	987	992	PF02991	0.431
LIG_LIR_Gen_1	146	154	PF02991	0.399
LIG_LIR_Gen_1	263	272	PF02991	0.435
LIG_LIR_Gen_1	372	381	PF02991	0.536
LIG_LIR_Gen_1	399	406	PF02991	0.456
LIG_LIR_Gen_1	580	590	PF02991	0.535
LIG_LIR_Gen_1	839	846	PF02991	0.478
LIG_LIR_Gen_1	874	880	PF02991	0.488
LIG_LIR_Gen_1	886	895	PF02991	0.263
LIG_LIR_Nem_3	100	104	PF02991	0.456
LIG_LIR_Nem_3	1012	1017	PF02991	0.443
LIG_LIR_Nem_3	146	151	PF02991	0.529
LIG_LIR_Nem_3	218	223	PF02991	0.580
LIG_LIR_Nem_3	263	267	PF02991	0.421
LIG_LIR_Nem_3	268	273	PF02991	0.395
LIG_LIR_Nem_3	372	378	PF02991	0.511
LIG_LIR_Nem_3	399	404	PF02991	0.490
LIG_LIR_Nem_3	580	586	PF02991	0.535
LIG_LIR_Nem_3	718	724	PF02991	0.431
LIG_LIR_Nem_3	789	793	PF02991	0.445
LIG_LIR_Nem_3	874	879	PF02991	0.503
LIG_LIR_Nem_3	886	891	PF02991	0.267
LIG_NRBOX	507	513	PF00104	0.481
LIG_PCNA_yPIPBox_3	443	457	PF02747	0.511
LIG_PCNA_yPIPBox_3	722	735	PF02747	0.474
LIG_PCNA_yPIPBox_3	882	896	PF02747	0.464
LIG_Pex14_1	771	775	PF04695	0.431
LIG_Pex14_2	666	670	PF04695	0.478
LIG_Pex14_2	986	990	PF04695	0.498
LIG_PTB_Apo_2	429	436	PF02174	0.535
LIG_PTB_Apo_2	656	663	PF02174	0.442
LIG_PTB_Apo_2	91	98	PF02174	0.454
LIG_PTB_Phospho_1	656	662	PF10480	0.442
LIG_PTB_Phospho_1	91	97	PF10480	0.434
LIG_SH2_CRK	1014	1018	PF00017	0.442
LIG_SH2_CRK	337	341	PF00017	0.463
LIG_SH2_CRK	375	379	PF00017	0.542
LIG_SH2_CRK	61	65	PF00017	0.427
LIG_SH2_CRK	721	725	PF00017	0.442
LIG_SH2_CRK	759	763	PF00017	0.478
LIG_SH2_NCK_1	81	85	PF00017	0.427
LIG_SH2_NCK_1	87	91	PF00017	0.396
LIG_SH2_PTP2	876	879	PF00017	0.365
LIG_SH2_SRC	1090	1093	PF00017	0.523
LIG_SH2_SRC	293	296	PF00017	0.449
LIG_SH2_STAP1	375	379	PF00017	0.474
LIG_SH2_STAP1	70	74	PF00017	0.342
LIG_SH2_STAP1	803	807	PF00017	0.526
LIG_SH2_STAT3	1088	1091	PF00017	0.508
LIG_SH2_STAT3	130	133	PF00017	0.466
LIG_SH2_STAT3	641	644	PF00017	0.431
LIG_SH2_STAT5	120	123	PF00017	0.340
LIG_SH2_STAT5	131	134	PF00017	0.370
LIG_SH2_STAT5	264	267	PF00017	0.371
LIG_SH2_STAT5	293	296	PF00017	0.366
LIG_SH2_STAT5	339	342	PF00017	0.457
LIG_SH2_STAT5	485	488	PF00017	0.351
LIG_SH2_STAT5	587	590	PF00017	0.486
LIG_SH2_STAT5	61	64	PF00017	0.427
LIG_SH2_STAT5	662	665	PF00017	0.447
LIG_SH2_STAT5	767	770	PF00017	0.442
LIG_SH2_STAT5	790	793	PF00017	0.520
LIG_SH2_STAT5	81	84	PF00017	0.321
LIG_SH2_STAT5	834	837	PF00017	0.468
LIG_SH2_STAT5	876	879	PF00017	0.495
LIG_SH2_STAT5	918	921	PF00017	0.451
LIG_SH3_3	129	135	PF00018	0.481
LIG_SH3_3	289	295	PF00018	0.478
LIG_SH3_3	306	312	PF00018	0.507
LIG_SH3_3	385	391	PF00018	0.500
LIG_SH3_3	467	473	PF00018	0.467
LIG_SH3_3	62	68	PF00018	0.290
LIG_SH3_3	731	737	PF00018	0.477
LIG_SH3_5	786	790	PF00018	0.442
LIG_Sin3_3	306	313	PF02671	0.505
LIG_SUMO_SIM_anti_2	15	24	PF11976	0.442
LIG_SUMO_SIM_anti_2	26	33	PF11976	0.365
LIG_SUMO_SIM_anti_2	593	598	PF11976	0.432
LIG_SUMO_SIM_anti_2	960	968	PF11976	0.537
LIG_SUMO_SIM_par_1	138	144	PF11976	0.550
LIG_SUMO_SIM_par_1	575	580	PF11976	0.476
LIG_SUMO_SIM_par_1	593	598	PF11976	0.397
LIG_SUMO_SIM_par_1	674	682	PF11976	0.461
LIG_SUMO_SIM_par_1	960	968	PF11976	0.542
LIG_TRAF2_1	233	236	PF00917	0.633
LIG_TRAF2_1	249	252	PF00917	0.547
LIG_TRAF2_1	951	954	PF00917	0.522
LIG_TYR_ITSM	1010	1017	PF00017	0.463
LIG_UBA3_1	367	373	PF00899	0.362
LIG_UBA3_1	594	600	PF00899	0.360
LIG_UBA3_1	961	969	PF00899	0.287
LIG_WRC_WIRS_1	257	262	PF05994	0.562
LIG_WRC_WIRS_1	934	939	PF05994	0.350
MOD_CDC14_SPxK_1	152	155	PF00782	0.505
MOD_CDK_SPK_2	595	600	PF00069	0.360
MOD_CDK_SPxK_1	149	155	PF00069	0.500
MOD_CK1_1	218	224	PF00069	0.525
MOD_CK1_1	402	408	PF00069	0.266
MOD_CK1_1	841	847	PF00069	0.579
MOD_CK1_1	855	861	PF00069	0.643
MOD_CK1_1	9	15	PF00069	0.476
MOD_CK2_1	1015	1021	PF00069	0.345
MOD_CK2_1	1090	1096	PF00069	0.449
MOD_CK2_1	170	176	PF00069	0.509
MOD_CK2_1	186	192	PF00069	0.666
MOD_CK2_1	20	26	PF00069	0.285
MOD_CK2_1	209	215	PF00069	0.773
MOD_CK2_1	246	252	PF00069	0.573
MOD_CK2_1	458	464	PF00069	0.354
MOD_CK2_1	490	496	PF00069	0.589
MOD_CK2_1	7	13	PF00069	0.536
MOD_CK2_1	860	866	PF00069	0.558
MOD_GlcNHglycan	1017	1020	PF01048	0.397
MOD_GlcNHglycan	207	210	PF01048	0.620
MOD_GlcNHglycan	220	223	PF01048	0.627
MOD_GlcNHglycan	225	228	PF01048	0.529
MOD_GlcNHglycan	23	26	PF01048	0.431
MOD_GlcNHglycan	422	425	PF01048	0.284
MOD_GlcNHglycan	561	564	PF01048	0.427
MOD_GlcNHglycan	651	654	PF01048	0.297
MOD_GlcNHglycan	708	711	PF01048	0.285
MOD_GlcNHglycan	846	849	PF01048	0.557
MOD_GlcNHglycan	890	894	PF01048	0.313
MOD_GSK3_1	1090	1097	PF00069	0.545
MOD_GSK3_1	170	177	PF00069	0.634
MOD_GSK3_1	200	207	PF00069	0.681
MOD_GSK3_1	211	218	PF00069	0.661
MOD_GSK3_1	246	253	PF00069	0.650
MOD_GSK3_1	3	10	PF00069	0.529
MOD_GSK3_1	396	403	PF00069	0.279
MOD_GSK3_1	409	416	PF00069	0.278
MOD_GSK3_1	485	492	PF00069	0.432
MOD_GSK3_1	534	541	PF00069	0.435
MOD_GSK3_1	555	562	PF00069	0.309
MOD_GSK3_1	577	584	PF00069	0.360
MOD_N-GLC_1	517	522	PF02516	0.554
MOD_N-GLC_1	855	860	PF02516	0.556
MOD_NEK2_1	104	109	PF00069	0.553
MOD_NEK2_1	1072	1077	PF00069	0.347
MOD_NEK2_1	396	401	PF00069	0.266
MOD_NEK2_1	458	463	PF00069	0.321
MOD_NEK2_1	490	495	PF00069	0.442
MOD_NEK2_1	572	577	PF00069	0.275
MOD_NEK2_1	581	586	PF00069	0.283
MOD_NEK2_1	809	814	PF00069	0.582
MOD_NEK2_1	854	859	PF00069	0.529
MOD_NEK2_1	92	97	PF00069	0.461
MOD_NEK2_1	964	969	PF00069	0.266
MOD_NEK2_1	975	980	PF00069	0.266
MOD_NEK2_1	985	990	PF00069	0.254
MOD_NEK2_2	1090	1095	PF00069	0.525
MOD_NEK2_2	299	304	PF00069	0.432
MOD_NEK2_2	935	940	PF00069	0.411
MOD_PIKK_1	1025	1031	PF00454	0.361
MOD_PIKK_1	156	162	PF00454	0.496
MOD_PIKK_1	341	347	PF00454	0.287
MOD_PIKK_1	373	379	PF00454	0.398
MOD_PIKK_1	389	395	PF00454	0.411
MOD_PIKK_1	43	49	PF00454	0.374
MOD_PIKK_1	581	587	PF00454	0.287
MOD_PIKK_1	860	866	PF00454	0.591
MOD_PIKK_1	918	924	PF00454	0.285
MOD_PIKK_1	941	947	PF00454	0.411
MOD_PKA_2	1042	1048	PF00069	0.510
MOD_PKA_2	197	203	PF00069	0.509
MOD_PKA_2	348	354	PF00069	0.266
MOD_PKA_2	478	484	PF00069	0.299
MOD_PKA_2	516	522	PF00069	0.485
MOD_PKA_2	6	12	PF00069	0.417
MOD_PKA_2	79	85	PF00069	0.550
MOD_PKA_2	860	866	PF00069	0.577
MOD_PKA_2	92	98	PF00069	0.440
MOD_PKA_2	941	947	PF00069	0.301
MOD_Plk_1	241	247	PF00069	0.725
MOD_Plk_1	250	256	PF00069	0.623
MOD_Plk_1	459	465	PF00069	0.348
MOD_Plk_1	517	523	PF00069	0.440
MOD_Plk_1	526	532	PF00069	0.424
MOD_Plk_2-3	13	19	PF00069	0.352
MOD_Plk_2-3	138	144	PF00069	0.385
MOD_Plk_2-3	263	269	PF00069	0.367
MOD_Plk_4	1009	1015	PF00069	0.376
MOD_Plk_4	126	132	PF00069	0.361
MOD_Plk_4	13	19	PF00069	0.383
MOD_Plk_4	215	221	PF00069	0.711
MOD_Plk_4	274	280	PF00069	0.462
MOD_Plk_4	396	402	PF00069	0.281
MOD_Plk_4	426	432	PF00069	0.421
MOD_Plk_4	478	484	PF00069	0.333
MOD_Plk_4	572	578	PF00069	0.308
MOD_Plk_4	59	65	PF00069	0.444
MOD_Plk_4	841	847	PF00069	0.501
MOD_Plk_4	92	98	PF00069	0.414
MOD_Plk_4	985	991	PF00069	0.266
MOD_ProDKin_1	143	149	PF00069	0.551
MOD_ProDKin_1	165	171	PF00069	0.696
MOD_ProDKin_1	174	180	PF00069	0.543
MOD_ProDKin_1	30	36	PF00069	0.376
MOD_ProDKin_1	595	601	PF00069	0.393
MOD_ProDKin_1	671	677	PF00069	0.331
MOD_ProDKin_1	708	714	PF00069	0.266
MOD_SUMO_rev_2	1018	1025	PF00179	0.511
MOD_SUMO_rev_2	798	807	PF00179	0.322
MOD_SUMO_rev_2	954	961	PF00179	0.364
TRG_DiLeu_BaEn_1	719	724	PF01217	0.266
TRG_DiLeu_BaEn_1	957	962	PF01217	0.287
TRG_DiLeu_BaEn_4	804	810	PF01217	0.411
TRG_DiLeu_BaLyEn_6	1012	1017	PF01217	0.455
TRG_DiLeu_BaLyEn_6	159	164	PF01217	0.506
TRG_DiLeu_BaLyEn_6	363	368	PF01217	0.381
TRG_DiLeu_BaLyEn_6	502	507	PF01217	0.514
TRG_ENDOCYTIC_2	101	104	PF00928	0.587
TRG_ENDOCYTIC_2	1014	1017	PF00928	0.441
TRG_ENDOCYTIC_2	264	267	PF00928	0.525
TRG_ENDOCYTIC_2	337	340	PF00928	0.310
TRG_ENDOCYTIC_2	375	378	PF00928	0.363
TRG_ENDOCYTIC_2	61	64	PF00928	0.427
TRG_ENDOCYTIC_2	721	724	PF00928	0.281
TRG_ENDOCYTIC_2	759	762	PF00928	0.484
TRG_ENDOCYTIC_2	790	793	PF00928	0.295
TRG_ENDOCYTIC_2	834	837	PF00928	0.401
TRG_ENDOCYTIC_2	842	845	PF00928	0.420
TRG_ENDOCYTIC_2	876	879	PF00928	0.409
TRG_ER_diArg_1	1003	1005	PF00400	0.281
TRG_ER_diArg_1	667	669	PF00400	0.411
TRG_ER_diArg_1	859	862	PF00400	0.513
TRG_ER_diArg_1	939	942	PF00400	0.272
TRG_ER_diArg_1	947	950	PF00400	0.258
TRG_NES_CRM1_1	864	874	PF08389	0.463
TRG_NLS_MonoExtC_3	442	447	PF00514	0.393
TRG_Pf-PMV_PEXEL_1	505	509	PF00026	0.445
TRG_Pf-PMV_PEXEL_1	896	900	PF00026	0.411

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5A7	Leptomonas seymouri	68%	100%
A0A0S4IUR7	Bodo saltans	39%	100%
A0A1X0NNS9	Trypanosomatidae	48%	100%
A0A3R7NZA3	Trypanosoma rangeli	47%	100%
A0A3S7WSQ7	Leishmania donovani	97%	100%
A4H7G5	Leishmania braziliensis	90%	100%
A4HVU6	Leishmania infantum	97%	100%
B6EU02	Leishmania tarentolae	94%	100%
C9ZT80	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	100%
E9APJ8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
Q4DCH3	Trypanosoma cruzi (strain CL Brener)	48%	100%
Q4QFY1	Leishmania major	100%	100%
Q57X81	Trypanosoma brucei brucei (strain 927/4 GUTat10.1)	44%	100%
V5BHQ6	Trypanosoma cruzi	48%	100%