P27_protein_putative/GeneDB:LmjF.28.0980

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

I1ZAQ0_LEIDO

TriTrypDb:

LdBPK_281070.1 , LdCL_280015300 , LDHU3_28.1280

Length:

240

Annotations

Annotations by Jardim et al.

Electron Transport Chain (see tricarboxylic acid section for Complex II), P27

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 16
NetGPI	no	yes: 0, no: 16

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	10
GO:0110165	cellular anatomical entity	1	10

Expansion

Sequence features

I1ZAQ0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	200	204	PF00082	0.636
DEG_APCC_DBOX_1	93	101	PF00400	0.441
DOC_CYCLIN_RxL_1	194	208	PF00134	0.340
DOC_PP1_RVXF_1	120	126	PF00149	0.290
DOC_PP1_RVXF_1	78	85	PF00149	0.473
DOC_PP4_FxxP_1	125	128	PF00568	0.291
DOC_USP7_MATH_1	233	237	PF00917	0.489
LIG_14-3-3_CanoR_1	122	126	PF00244	0.329
LIG_BIR_II_1	1	5	PF00653	0.591
LIG_BRCT_BRCA1_1	115	119	PF00533	0.267
LIG_BRCT_BRCA1_1	68	72	PF00533	0.574
LIG_EH_1	29	33	PF12763	0.556
LIG_FHA_1	108	114	PF00498	0.327
LIG_FHA_1	170	176	PF00498	0.339
LIG_FHA_1	3	9	PF00498	0.598
LIG_IBAR_NPY_1	76	78	PF08397	0.493
LIG_LIR_Apic_2	124	128	PF02991	0.332
LIG_LIR_LC3C_4	110	113	PF02991	0.218
LIG_LIR_Nem_3	116	121	PF02991	0.295
LIG_Pex14_1	55	59	PF04695	0.495
LIG_REV1ctd_RIR_1	70	76	PF16727	0.473
LIG_SH2_CRK	61	65	PF00017	0.510
LIG_SH2_GRB2like	205	208	PF00017	0.337
LIG_SH2_PTP2	23	26	PF00017	0.477
LIG_SH2_SRC	189	192	PF00017	0.316
LIG_SH2_STAP1	115	119	PF00017	0.303
LIG_SH2_STAT5	189	192	PF00017	0.345
LIG_SH2_STAT5	23	26	PF00017	0.483
LIG_SH2_STAT5	44	47	PF00017	0.520
LIG_SH2_STAT5	81	84	PF00017	0.493
LIG_SH3_4	141	148	PF00018	0.362
LIG_SUMO_SIM_anti_2	110	116	PF11976	0.393
LIG_SUMO_SIM_par_1	110	116	PF11976	0.310
MOD_CK1_1	2	8	PF00069	0.597
MOD_CK1_1	9	15	PF00069	0.589
MOD_CK1_1	99	105	PF00069	0.554
MOD_CK2_1	85	91	PF00069	0.476
MOD_GlcNHglycan	224	229	PF01048	0.607
MOD_GlcNHglycan	235	238	PF01048	0.667
MOD_GlcNHglycan	48	51	PF01048	0.301
MOD_GlcNHglycan	8	11	PF01048	0.407
MOD_GSK3_1	113	120	PF00069	0.318
MOD_GSK3_1	2	9	PF00069	0.642
MOD_GSK3_1	99	106	PF00069	0.519
MOD_NEK2_1	117	122	PF00069	0.412
MOD_NEK2_1	137	142	PF00069	0.290
MOD_NEK2_1	85	90	PF00069	0.476
MOD_NEK2_2	128	133	PF00069	0.269
MOD_NEK2_2	212	217	PF00069	0.295
MOD_PKA_2	121	127	PF00069	0.332
MOD_PKA_2	2	8	PF00069	0.567
MOD_Plk_1	128	134	PF00069	0.270
MOD_Plk_1	167	173	PF00069	0.356
MOD_Plk_1	200	206	PF00069	0.412
MOD_Plk_1	85	91	PF00069	0.476
MOD_Plk_2-3	86	92	PF00069	0.476
MOD_Plk_4	103	109	PF00069	0.316
MOD_Plk_4	113	119	PF00069	0.285
MOD_Plk_4	121	127	PF00069	0.310
MOD_Plk_4	200	206	PF00069	0.337
TRG_ENDOCYTIC_2	160	163	PF00928	0.330
TRG_ENDOCYTIC_2	61	64	PF00928	0.510
TRG_NES_CRM1_1	173	187	PF08389	0.370

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HYK0	Leptomonas seymouri	63%	99%
A0A0S4IVH5	Bodo saltans	48%	99%
A0A0S4IXX7	Bodo saltans	48%	91%
A0A1X0NYZ9	Trypanosomatidae	63%	100%
A0A3Q8IGT4	Leishmania donovani	61%	100%
A0A422MZK8	Trypanosoma rangeli	62%	100%
A4HGE2	Leishmania braziliensis	83%	100%
A4HLG1	Leishmania braziliensis	60%	100%
A4I3H5	Leishmania infantum	100%	100%
A4I8X2	Leishmania infantum	61%	100%
E9AZR4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
E9B3U1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	63%	100%
Q4Q483	Leishmania major	62%	100%
Q4Q8G9	Leishmania major	94%	100%
V5AL49	Trypanosoma cruzi	63%	94%