Ch36-1190 protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Ch36-1190 protein

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

H2ALR9_LEIDO

TriTrypDb:

LdBPK_361190.1 , LdCL_360017000

Length:

455

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 6
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

H2ALR9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	326	330	PF00656	0.283
CLV_NRD_NRD_1	270	272	PF00675	0.313
CLV_PCSK_KEX2_1	270	272	PF00082	0.317
CLV_PCSK_SKI1_1	234	238	PF00082	0.328
CLV_PCSK_SKI1_1	392	396	PF00082	0.353
CLV_PCSK_SKI1_1	6	10	PF00082	0.456
CLV_PCSK_SKI1_1	90	94	PF00082	0.375
DEG_APCC_DBOX_1	233	241	PF00400	0.280
DEG_Nend_UBRbox_3	1	3	PF02207	0.318
DEG_SPOP_SBC_1	52	56	PF00917	0.300
DOC_CDC14_PxL_1	136	144	PF14671	0.260
DOC_CYCLIN_RxL_1	333	344	PF00134	0.256
DOC_CYCLIN_yCln2_LP_2	390	396	PF00134	0.251
DOC_CYCLIN_yCln2_LP_2	92	98	PF00134	0.341
DOC_MAPK_DCC_7	195	203	PF00069	0.282
DOC_MAPK_HePTP_8	192	204	PF00069	0.268
DOC_MAPK_HePTP_8	350	362	PF00069	0.303
DOC_MAPK_MEF2A_6	195	204	PF00069	0.286
DOC_MAPK_MEF2A_6	338	347	PF00069	0.257
DOC_MAPK_MEF2A_6	353	362	PF00069	0.256
DOC_PP2B_LxvP_1	92	95	PF13499	0.366
DOC_PP4_FxxP_1	30	33	PF00568	0.315
DOC_USP7_MATH_1	149	153	PF00917	0.269
DOC_USP7_MATH_1	215	219	PF00917	0.414
DOC_USP7_MATH_1	327	331	PF00917	0.275
DOC_USP7_MATH_1	341	345	PF00917	0.232
DOC_USP7_MATH_1	53	57	PF00917	0.318
DOC_WW_Pin1_4	151	156	PF00397	0.294
DOC_WW_Pin1_4	81	86	PF00397	0.317
LIG_14-3-3_CanoR_1	189	199	PF00244	0.275
LIG_14-3-3_CanoR_1	223	233	PF00244	0.302
LIG_14-3-3_CanoR_1	425	431	PF00244	0.343
LIG_14-3-3_CanoR_1	6	11	PF00244	0.287
LIG_BIR_III_4	43	47	PF00653	0.279
LIG_BRCT_BRCA1_1	161	165	PF00533	0.243
LIG_BRCT_BRCA1_1	38	42	PF00533	0.225
LIG_Clathr_ClatBox_1	360	364	PF01394	0.361
LIG_EH1_1	272	280	PF00400	0.293
LIG_eIF4E_1	273	279	PF01652	0.324
LIG_FHA_1	118	124	PF00498	0.280
LIG_FHA_1	243	249	PF00498	0.287
LIG_FHA_1	407	413	PF00498	0.278
LIG_FHA_2	191	197	PF00498	0.262
LIG_FHA_2	418	424	PF00498	0.328
LIG_FHA_2	52	58	PF00498	0.340
LIG_FHA_2	82	88	PF00498	0.294
LIG_LIR_Apic_2	28	33	PF02991	0.312
LIG_LIR_Gen_1	384	394	PF02991	0.297
LIG_LIR_Gen_1	39	50	PF02991	0.313
LIG_LIR_LC3C_4	359	362	PF02991	0.335
LIG_LIR_Nem_3	168	174	PF02991	0.304
LIG_LIR_Nem_3	28	34	PF02991	0.529
LIG_LIR_Nem_3	373	377	PF02991	0.326
LIG_LIR_Nem_3	384	390	PF02991	0.262
LIG_LIR_Nem_3	39	45	PF02991	0.265
LIG_LYPXL_yS_3	139	142	PF13949	0.280
LIG_MYND_3	435	439	PF01753	0.314
LIG_PDZ_Class_3	450	455	PF00595	0.463
LIG_Pex14_2	399	403	PF04695	0.272
LIG_SH2_CRK	397	401	PF00017	0.303
LIG_SH2_GRB2like	396	399	PF00017	0.298
LIG_SH2_STAT5	147	150	PF00017	0.286
LIG_SH2_STAT5	153	156	PF00017	0.241
LIG_SH2_STAT5	158	161	PF00017	0.242
LIG_SH2_STAT5	374	377	PF00017	0.352
LIG_SH3_3	134	140	PF00018	0.289
LIG_SH3_3	219	225	PF00018	0.384
LIG_SH3_3	308	314	PF00018	0.285
LIG_SUMO_SIM_anti_2	359	364	PF11976	0.368
LIG_SUMO_SIM_par_1	296	302	PF11976	0.359
LIG_SUMO_SIM_par_1	338	344	PF11976	0.266
LIG_SUMO_SIM_par_1	359	364	PF11976	0.335
LIG_SxIP_EBH_1	424	437	PF03271	0.331
LIG_TRAF2_1	286	289	PF00917	0.364
LIG_UBA3_1	386	395	PF00899	0.259
LIG_WRC_WIRS_1	400	405	PF05994	0.279
MOD_CK1_1	113	119	PF00069	0.300
MOD_CK1_1	25	31	PF00069	0.249
MOD_CK2_1	191	197	PF00069	0.409
MOD_CK2_1	229	235	PF00069	0.343
MOD_CK2_1	51	57	PF00069	0.330
MOD_CK2_1	81	87	PF00069	0.290
MOD_GlcNHglycan	24	27	PF01048	0.243
MOD_GlcNHglycan	325	328	PF01048	0.308
MOD_GlcNHglycan	329	332	PF01048	0.272
MOD_GlcNHglycan	403	406	PF01048	0.288
MOD_GlcNHglycan	69	72	PF01048	0.379
MOD_GSK3_1	106	113	PF00069	0.300
MOD_GSK3_1	147	154	PF00069	0.265
MOD_GSK3_1	238	245	PF00069	0.364
MOD_GSK3_1	323	330	PF00069	0.306
MOD_N-GLC_1	181	186	PF02516	0.291
MOD_N-GLC_1	190	195	PF02516	0.264
MOD_NEK2_1	159	164	PF00069	0.276
MOD_NEK2_1	239	244	PF00069	0.392
MOD_NEK2_1	323	328	PF00069	0.318
MOD_NEK2_1	34	39	PF00069	0.274
MOD_NEK2_1	399	404	PF00069	0.282
MOD_NEK2_1	8	13	PF00069	0.291
MOD_NEK2_2	341	346	PF00069	0.212
MOD_PIKK_1	159	165	PF00454	0.269
MOD_PIKK_1	255	261	PF00454	0.307
MOD_PIKK_1	406	412	PF00454	0.269
MOD_PKA_2	445	451	PF00069	0.373
MOD_Plk_1	181	187	PF00069	0.303
MOD_Plk_4	181	187	PF00069	0.407
MOD_Plk_4	356	362	PF00069	0.499
MOD_Plk_4	426	432	PF00069	0.341
MOD_ProDKin_1	151	157	PF00069	0.294
MOD_ProDKin_1	81	87	PF00069	0.320
MOD_SUMO_for_1	253	256	PF00179	0.308
MOD_SUMO_for_1	436	439	PF00179	0.462
TRG_DiLeu_BaEn_1	197	202	PF01217	0.298
TRG_DiLeu_BaEn_2	234	240	PF01217	0.282
TRG_ENDOCYTIC_2	139	142	PF00928	0.245
TRG_ENDOCYTIC_2	158	161	PF00928	0.206
TRG_ENDOCYTIC_2	374	377	PF00928	0.333
TRG_ENDOCYTIC_2	396	399	PF00928	0.397
TRG_ER_diArg_1	270	272	PF00400	0.313
TRG_NLS_MonoExtN_4	314	319	PF00514	0.277

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5Q9	Leptomonas seymouri	54%	88%
A0A0S4JAW3	Bodo saltans	27%	100%
A4HNX3	Leishmania braziliensis	77%	100%
A4ICM1	Leishmania infantum	99%	100%
E9ASN3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q1W3	Leishmania major	93%	100%