Methyltransf_11 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B740_LEIMU

TriTrypDb:

LmxM.34.5140

Length:

286

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B740

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B740

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	34	36	PF00675	0.596
CLV_PCSK_SKI1_1	172	176	PF00082	0.489
DEG_Nend_UBRbox_3	1	3	PF02207	0.713
DEG_SPOP_SBC_1	106	110	PF00917	0.746
DOC_MAPK_gen_1	212	222	PF00069	0.436
DOC_MAPK_JIP1_4	215	221	PF00069	0.538
DOC_PP1_RVXF_1	10	16	PF00149	0.342
DOC_USP7_MATH_1	105	109	PF00917	0.739
DOC_WW_Pin1_4	148	153	PF00397	0.547
DOC_WW_Pin1_4	229	234	PF00397	0.494
LIG_14-3-3_CanoR_1	170	175	PF00244	0.430
LIG_14-3-3_CanoR_1	271	279	PF00244	0.460
LIG_deltaCOP1_diTrp_1	14	19	PF00928	0.527
LIG_FAT_LD_1	96	104	PF03623	0.537
LIG_FHA_1	112	118	PF00498	0.424
LIG_FHA_1	205	211	PF00498	0.263
LIG_FHA_1	248	254	PF00498	0.377
LIG_FHA_1	78	84	PF00498	0.580
LIG_HCF-1_HBM_1	17	20	PF13415	0.594
LIG_LIR_Gen_1	14	20	PF02991	0.499
LIG_LIR_Nem_3	14	19	PF02991	0.503
LIG_LIR_Nem_3	270	275	PF02991	0.452
LIG_LIR_Nem_3	51	56	PF02991	0.459
LIG_Pex14_1	16	20	PF04695	0.490
LIG_Pex14_1	52	56	PF04695	0.389
LIG_Pex14_2	15	19	PF04695	0.494
LIG_RPA_C_Fungi	160	172	PF08784	0.357
LIG_SH2_CRK	277	281	PF00017	0.453
LIG_SH2_NCK_1	277	281	PF00017	0.453
LIG_SH2_STAP1	249	253	PF00017	0.493
LIG_SH2_STAP1	277	281	PF00017	0.474
LIG_SH2_STAP1	50	54	PF00017	0.445
LIG_SH2_STAP1	59	63	PF00017	0.453
LIG_SH2_STAT5	206	209	PF00017	0.346
LIG_SH2_STAT5	234	237	PF00017	0.448
LIG_SH2_STAT5	249	252	PF00017	0.516
LIG_SH3_3	210	216	PF00018	0.503
LIG_SH3_3	227	233	PF00018	0.335
LIG_SUMO_SIM_anti_2	178	184	PF11976	0.434
LIG_SUMO_SIM_par_1	221	229	PF11976	0.558
LIG_TYR_ITIM	247	252	PF00017	0.573
LIG_WRC_WIRS_1	192	197	PF05994	0.573
LIG_WRC_WIRS_1	242	247	PF05994	0.566
MOD_CK1_1	108	114	PF00069	0.711
MOD_CK1_1	150	156	PF00069	0.648
MOD_CK1_1	224	230	PF00069	0.588
MOD_CK1_1	270	276	PF00069	0.509
MOD_GlcNHglycan	110	113	PF01048	0.464
MOD_GlcNHglycan	236	239	PF01048	0.489
MOD_GlcNHglycan	281	284	PF01048	0.532
MOD_GSK3_1	107	114	PF00069	0.703
MOD_GSK3_1	146	153	PF00069	0.496
MOD_GSK3_1	69	76	PF00069	0.316
MOD_LATS_1	262	268	PF00433	0.602
MOD_N-GLC_2	142	144	PF02516	0.419
MOD_NEK2_1	146	151	PF00069	0.439
MOD_NEK2_1	191	196	PF00069	0.551
MOD_NEK2_1	221	226	PF00069	0.538
MOD_NEK2_2	59	64	PF00069	0.263
MOD_PKA_2	270	276	PF00069	0.472
MOD_PKA_2	42	48	PF00069	0.512
MOD_Plk_1	59	65	PF00069	0.267
MOD_Plk_4	150	156	PF00069	0.540
MOD_Plk_4	42	48	PF00069	0.512
MOD_ProDKin_1	148	154	PF00069	0.558
MOD_ProDKin_1	229	235	PF00069	0.488
TRG_DiLeu_BaEn_1	42	47	PF01217	0.496
TRG_ENDOCYTIC_2	249	252	PF00928	0.573
TRG_ENDOCYTIC_2	277	280	PF00928	0.440
TRG_ENDOCYTIC_2	50	53	PF00928	0.446
TRG_ER_diArg_1	169	172	PF00400	0.496
TRG_Pf-PMV_PEXEL_1	261	266	PF00026	0.488
TRG_Pf-PMV_PEXEL_1	38	42	PF00026	0.537

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HTH2	Leptomonas seymouri	64%	100%
A0A3S7XA23	Leishmania donovani	88%	100%
A4HNH6	Leishmania braziliensis	77%	100%
A4IC32	Leishmania infantum	88%	100%
E9AFY7	Leishmania major	89%	100%